Class information for:
Level 1: CXCR4//CXCL12//CXCR7

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1531 2610 48.3 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
578 3       CHEMOKINES//CXCR4//MACROPHAGE MIGRATION INHIBITORY FACTOR 16225
546 2             CHEMOKINES//CXCR4//CHEMOKINE RECEPTOR 14674
1531 1                   CXCR4//CXCL12//CXCR7 2610

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CXCR4 authKW 3278737 28% 39% 720
2 CXCL12 authKW 1590921 11% 49% 276
3 CXCR7 authKW 1217179 5% 82% 127
4 SDF 1 authKW 860872 7% 38% 193
5 CHEMOKINE RECEPTOR authKW 295601 8% 12% 205
6 STROMAL CELL DERIVED FACTOR 1 authKW 294276 3% 35% 72
7 CHEMOKINES authKW 203666 16% 4% 414
8 SDF 1 ALPHA authKW 197870 2% 32% 53
9 CXCR4 ANTAGONIST authKW 185590 1% 55% 29
10 AMD3100 authKW 174145 2% 34% 44

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 11805 35% 0% 926
2 Hematology 2734 11% 0% 275
3 Cell Biology 1829 15% 0% 396
4 Medicine, Research & Experimental 1082 9% 0% 226
5 Immunology 880 10% 0% 274
6 Cell & Tissue Engineering 816 2% 0% 45
7 Biochemistry & Molecular Biology 407 15% 0% 386
8 Pathology 372 4% 0% 106
9 Chemistry, Medicinal 154 3% 0% 80
10 Neurosciences 85 6% 0% 159

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNITE IMMUNOL VIRALE 33292 1% 19% 15
2 PHARMACEUT RADIOCHEM 24354 0% 21% 10
3 GASTROINTESTINAL CANC SECT 23395 0% 100% 2
4 INVEST NEUROQUIM IUIN 23395 0% 100% 2
5 NEUROSCI PHARMA AB MOL PHARMACOL 23395 0% 100% 2
6 GOLDYNE SAVAD GENE THER Y 21820 1% 9% 21
7 OROMAXILLO IAL HEAD NECK SURG 21252 0% 18% 10
8 MED SYST CONTROL 18300 0% 26% 6
9 SERV INMUNOONCOL 17543 0% 50% 3
10 SERV PHARMACOL NEUROSCI 17543 0% 50% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOR BIOLOGY 2686 1% 1% 38
2 ONCOLOGY REPORTS 2111 2% 0% 43
3 CLINICAL & EXPERIMENTAL METASTASIS 2082 1% 1% 19
4 MOLECULAR CANCER RESEARCH 1998 1% 1% 18
5 BLOOD 1848 3% 0% 76
6 THERANOSTICS 1599 0% 2% 9
7 STEM CELLS AND DEVELOPMENT 1304 1% 1% 16
8 MOLECULAR CANCER 1271 1% 1% 14
9 STEM CELLS 1163 1% 0% 21
10 CLINICAL CANCER RESEARCH 1133 1% 0% 39

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CXCR4 3278737 28% 39% 720 Search CXCR4 Search CXCR4
2 CXCL12 1590921 11% 49% 276 Search CXCL12 Search CXCL12
3 CXCR7 1217179 5% 82% 127 Search CXCR7 Search CXCR7
4 SDF 1 860872 7% 38% 193 Search SDF+1 Search SDF+1
5 CHEMOKINE RECEPTOR 295601 8% 12% 205 Search CHEMOKINE+RECEPTOR Search CHEMOKINE+RECEPTOR
6 STROMAL CELL DERIVED FACTOR 1 294276 3% 35% 72 Search STROMAL+CELL+DERIVED+FACTOR+1 Search STROMAL+CELL+DERIVED+FACTOR+1
7 CHEMOKINES 203666 16% 4% 414 Search CHEMOKINES Search CHEMOKINES
8 SDF 1 ALPHA 197870 2% 32% 53 Search SDF+1+ALPHA Search SDF+1+ALPHA
9 CXCR4 ANTAGONIST 185590 1% 55% 29 Search CXCR4+ANTAGONIST Search CXCR4+ANTAGONIST
10 AMD3100 174145 2% 34% 44 Search AMD3100 Search AMD3100

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 AZAD, BB , NIMMAGADDA, S , CHATTERJEE, S , (2014) THE INTRICATE ROLE OF CXCR4 IN CANCER.EMERGING APPLICATIONS OF MOLECULAR IMAGING TO ONCOLOGY. VOL. 124. ISSUE . P. 31 -82 190 72% 39
2 GUO, F , WANG, Y , LIU, J , MOK, SC , XUE, F , ZHANG, W , (2016) CXCL12/CXCR4: A SYMBIOTIC BRIDGE LINKING CANCER CELLS AND THEIR STROMAL NEIGHBORS IN ONCOGENIC COMMUNICATION NETWORKS.ONCOGENE. VOL. 35. ISSUE 7. P. 816 -826 98 60% 16
3 FURUSATO, B , MOHAMED, A , UHLEN, M , RHIM, JS , (2010) CXCR4 AND CANCER.PATHOLOGY INTERNATIONAL. VOL. 60. ISSUE 7. P. 497 -505 110 75% 126
4 PUCHERT, M , ENGELE, J , (2014) THE PECULIARITIES OF THE SDF-1/CXCL12 SYSTEM: IN SOME CELLS, CXCR4 AND CXCR7 SING SOLOS, IN OTHERS, THEY SING DUETS.CELL AND TISSUE RESEARCH. VOL. 355. ISSUE 2. P. 239 -253 121 74% 13
5 MISHAN, MA , AHMADIANKIA, N , BAHRAMI, AR , (2016) CXCR4 AND CCR7: TWO ELIGIBLE TARGETS IN TARGETED CANCER THERAPY.CELL BIOLOGY INTERNATIONAL. VOL. 40. ISSUE 9. P. 955 -967 114 79% 0
6 SHIM, H , OISHI, S , FUJII, N , (2009) CHEMOKINE RECEPTOR CXCR4 AS A THERAPEUTIC TARGET FOR NEUROECTODERMAL TUMORS.SEMINARS IN CANCER BIOLOGY. VOL. 19. ISSUE 2. P. 123 -134 155 63% 16
7 SUN, XQ , CHENG, GC , HAO, MG , ZHENG, JH , ZHOU, XM , ZHANG, JA , TAICHMAN, RS , PIENTA, KJ , WANG, JH , (2010) CXCL12/CXCR4/CXCR7 CHEMOKINE AXIS AND CANCER PROGRESSION.CANCER AND METASTASIS REVIEWS. VOL. 29. ISSUE 4. P. 709 -722 88 68% 256
8 LIEKENS, S , SCHOLS, D , HATSE, S , (2010) CXCL12-CXCR4 AXIS IN ANGIOGENESIS, METASTASIS AND STEM CELL MOBILIZATION.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 35. P. 3903-3920 135 59% 69
9 KUIL, J , BUCKLE, T , VAN LEEUWEN, FWB , (2012) IMAGING AGENTS FOR THE CHEMOKINE RECEPTOR 4 (CXCR4).CHEMICAL SOCIETY REVIEWS. VOL. 41. ISSUE 15. P. 5239-5261 131 62% 24
10 ZHAO, HL , GUO, LY , ZHAO, H , ZHAO, JX , WENG, H , ZHAO, B , (2015) CXCR4 OVER-EXPRESSION AND SURVIVAL IN CANCER: A SYSTEM REVIEW AND META-ANALYSIS.ONCOTARGET. VOL. 6. ISSUE 7. P. 5022 -5040 78 80% 22

Classes with closest relation at Level 1


Rank Class id link
1 32925 MYELOKATHEXIS//WHIM SYNDROME//INSERM UMR S996
2 16547 CCL20//CCR6//CCL21
3 18490 CHEMOKINE STRUCTURE//LYMPHOTACTIN//CYTOKINE RECEPTOR INTERACTIONS
4 32453 CXCL14//DBC2//BRAK
5 14765 CXCR2//INTERLEUKIN 8//CXCL5
6 28577 CXCL16//CXCR6//SR PSOX
7 21780 DARC//DUFFY BLOOD GROUP//DUFFY ANTIGEN
8 7432 BB 10010//CCL2//LEUKOTACTIN 1
9 14960 CHEMOKINES//CHEMOKINE RECEPTOR//EXPT CLIN NEUROL
10 772 CCR5//CCR5 ANTAGONIST//MARAVIROC

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