Class information for:
Level 1: TRANSCRIPTION FACTOR DECOY//DECOY//NF KAPPA B DECOY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24918 297 41.3 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
389 2             NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//OLIGONUCLEOTIDES//PEPTIDE NUCLEIC ACID 16949
24918 1                   TRANSCRIPTION FACTOR DECOY//DECOY//NF KAPPA B DECOY 297

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRANSCRIPTION FACTOR DECOY authKW 1060417 6% 54% 19
2 DECOY authKW 914188 11% 26% 34
3 NF KAPPA B DECOY authKW 541108 3% 53% 10
4 CLIN GENE THER Y MED address 308437 1% 100% 3
5 TRANSCRIPTION FACTOR DECOY TFD authKW 308437 1% 100% 3
6 PNA DNA CHIMERAS authKW 246742 2% 40% 6
7 GENE THER Y SCI address 237488 10% 8% 29
8 CRYBP1 authKW 205624 1% 100% 2
9 SYNTHETIC DOUBLE STRANDED OLIGODEOXYNUCLEOTIDE authKW 205624 1% 100% 2
10 CLIN GENE THER Y address 198211 7% 9% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medicine, Research & Experimental 573 17% 0% 51
2 Biochemistry & Molecular Biology 359 31% 0% 93
3 Biotechnology & Applied Microbiology 250 13% 0% 40
4 Peripheral Vascular Diseases 208 8% 0% 25
5 Genetics & Heredity 168 11% 0% 33
6 Cardiac & Cardiovascular System 154 10% 0% 30
7 Pharmacology & Pharmacy 108 13% 0% 40
8 Cell Biology 90 11% 0% 32
9 Biophysics 82 7% 0% 21
10 Chemistry, Medicinal 73 5% 0% 16

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN GENE THER Y MED 308437 1% 100% 3
2 GENE THER Y SCI 237488 10% 8% 29
3 CLIN GENE THER Y 198211 7% 9% 22
4 ER GENTECH 197700 3% 19% 10
5 KOREAN MINIST SCI TECHNOL 115660 1% 38% 3
6 BIOL MOL CELLULARIE CANC 102812 0% 100% 1
7 BRINDAVAN 102812 0% 100% 1
8 DEV PHARMACOL PHARMACOGEN TREATMENT THALASS 102812 0% 100% 1
9 DEV PHARMACOL PHARMACOGENOM TREATMENT THALA 102812 0% 100% 1
10 DIPARTIMENTO BIOMED TER IE AVANZATE 102812 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE THERAPY 5896 5% 0% 15
2 JOURNAL OF GENE MEDICINE 3574 2% 0% 7
3 CURRENT DRUG TARGETS 2750 2% 0% 7
4 CURRENT OPINION IN MOLECULAR THERAPEUTICS 1876 1% 0% 4
5 MINERVA BIOTECNOLOGICA 1733 1% 1% 3
6 CURRENT GENE THERAPY 746 1% 0% 2
7 EXPERIMENTAL NEPHROLOGY 742 1% 0% 2
8 JOURNAL OF CELL COMMUNICATION AND SIGNALING 434 0% 0% 1
9 CIRCULATION RESEARCH 357 2% 0% 6
10 ONCOLOGY RESEARCH 339 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRANSCRIPTION FACTOR DECOY 1060417 6% 54% 19 Search TRANSCRIPTION+FACTOR+DECOY Search TRANSCRIPTION+FACTOR+DECOY
2 DECOY 914188 11% 26% 34 Search DECOY Search DECOY
3 NF KAPPA B DECOY 541108 3% 53% 10 Search NF+KAPPA+B+DECOY Search NF+KAPPA+B+DECOY
4 TRANSCRIPTION FACTOR DECOY TFD 308437 1% 100% 3 Search TRANSCRIPTION+FACTOR+DECOY+TFD Search TRANSCRIPTION+FACTOR+DECOY+TFD
5 PNA DNA CHIMERAS 246742 2% 40% 6 Search PNA+DNA+CHIMERAS Search PNA+DNA+CHIMERAS
6 CRYBP1 205624 1% 100% 2 Search CRYBP1 Search CRYBP1
7 SYNTHETIC DOUBLE STRANDED OLIGODEOXYNUCLEOTIDE 205624 1% 100% 2 Search SYNTHETIC+DOUBLE+STRANDED+OLIGODEOXYNUCLEOTIDE Search SYNTHETIC+DOUBLE+STRANDED+OLIGODEOXYNUCLEOTIDE
8 DECOY OLIGODEOXYNUCLEOTIDE 194794 2% 32% 6 Search DECOY+OLIGODEOXYNUCLEOTIDE Search DECOY+OLIGODEOXYNUCLEOTIDE
9 DECOY STRATEGY 185060 1% 60% 3 Search DECOY+STRATEGY Search DECOY+STRATEGY
10 CIS ELEMENT DECOY 182773 1% 44% 4 Search CIS+ELEMENT+DECOY Search CIS+ELEMENT+DECOY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GAMBARI, R , (2004) NEW TRENDS IN THE DEVELOPMENT OF TRANSCRIPTION FACTOR DECOY (TFD) PHARMACOTHERAPY.CURRENT DRUG TARGETS. VOL. 5. ISSUE 5. P. 419-430 49 34% 22
2 BORGATTI, M , BEZZERRI, V , NICOLIS, E , LAMPRONTI, I , DECHECCHI, MC , MANCINI, I , TAMANINI, A , CABRINI, G , GAMBARI, R , (2010) DECOY OLIGODEOXYRIBONUCLEOTIDES AND PEPTIDE NUCLEIC ACIDS-DNA CHIMERAS TARGETING NUCLEAR FACTOR KAPPA-B: INHIBITION OF IL-8 GENE EXPRESSION IN CYSTIC FIBROSIS CELLS INFECTED WITH PSEUDOMONAS AERUGINOSA.BIOCHEMICAL PHARMACOLOGY. VOL. 80. ISSUE 12. P. 1887 -1894 29 36% 14
3 DE STEFANO, D , (2011) OLIGONUCLEOTIDES DECOY TO NF-KAPPAB: BECOMING A REALITY?.DISCOVERY MEDICINE. VOL. 12. ISSUE 63. P. 97 -105 28 37% 9
4 MANN, MJ , (2005) TRANSCRIPTION FACTOR DECOYS - A NEW MODEL FOR DISEASE INTERVENTION.THERAPEUTIC OLIGONUCLEOTIDES: TRANSCRIPTIONAL AND TRANSLATIONAL STRATEGIES FOR SILENCING GENE EXPRESSION. VOL. 1058. ISSUE . P. 128 -139 24 49% 15
5 METELEV, VG , KUBAREVA, EA , ORETSKAYA, TS , (2013) REGULATION OF ACTIVITY OF TRANSCRIPTION FACTOR NF-KAPPA B BY SYNTHETIC OLIGONUCLEOTIDES.BIOCHEMISTRY-MOSCOW. VOL. 78. ISSUE 8. P. 867-878 26 36% 2
6 MORISHITA, R , TOMITA, N , KANEDA, Y , OGIHARA, T , (2004) MOLECULAR THERAPY TO INHIBIT NF KAPPA B ACTIVATION BY TRANSCRIPTION FACTOR DECOY OLIGONUCLEOTIDES.CURRENT OPINION IN PHARMACOLOGY. VOL. 4. ISSUE 2. P. 139-146 19 48% 67
7 PENOLAZZI, L , BORGATTI, M , LAMBERTINI, E , MISCHIAT, C , FINOTTI, A , ROMANELLI, A , SAVIANO, M , PEDONE, C , PIVA, R , GAMBARI, R , (2004) PEPTIDE NUCLEIC ACID-DNA DECOY CHIMERAS TARGETING NF-KAPPA B TRANSCRIPTION FACTORS: INDUCTION OF APOPTOSIS IN HUMAN PRIMARY OSTEOCLASTS.INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. VOL. 14. ISSUE 2. P. 145-152 22 44% 15
8 OSAKO, MK , NAKAGAMI, H , MORISHITA, R , (2012) DEVELOPMENT AND MODIFICATION OF DECOY OLIGODEOXYNUCLEOTIDES FOR CLINICAL APPLICATION.NUCLEIC ACID DRUGS. VOL. 249. ISSUE . P. 49 -59 14 56% 1
9 DE STEFANO, D , DE ROSA, G , CARNUCCIO, R , (2010) NF KAPPA B DECOY OLIGONUCLEOTIDES.CURRENT OPINION IN MOLECULAR THERAPEUTICS. VOL. 12. ISSUE 2. P. 203 -213 32 24% 13
10 BENE, A , KURTEN, RC , CHAMBERS, TC , (2004) SUBCELLULAR LOCALIZATION AS A LIMITING FACTOR FOR UTILIZATION OF DECOY OLIGONUCLEOTIDES.NUCLEIC ACIDS RESEARCH. VOL. 32. ISSUE 19. P. - 12 67% 13

Classes with closest relation at Level 1


Rank Class id link
1 9238 RESTENOSIS//GENE THERAPY//LOCAL DRUG DELIVERY
2 28042 CROSS LINKED DNA DUPLEXES//OLIGONUCLEOTIDE 3 PHOSPHOROTHIOATES//OLIGONUCLEOTIDE MODIFICATION
3 500 NF KAPPA B//IKK//I KAPPA B
4 6706 PEPTIDE NUCLEIC ACID//PNA//BIOMOL RECOGNIT
5 2407 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT//ANTISENSE OLIGONUCLEOTIDES//ANTISENSE RESEARCH AND DEVELOPMENT
6 36415 VACCINE NANOTECHNOL//NANOPARTICULATE VACCINE//WHOLE CELL LYSATE
7 32849 TRANSCRIPTION FACTOR DETECTION//MOL IMAGING PROBES//CELL NUCLEAR EXTRACTS
8 11241 CYSTIC FIBROSIS//INFECT CYST FIBROSIS UNIT//ANTI INFLAMMATORY AGENTS ADMINISTRATION DOSAGE ADVERSE EFFECTS
9 19664 NF KAPPA B//SECT ZOOL CYTOL//1 C V
10 36785 GRAPTOPETALUM PARAGUAYENSE E WALTHER//GRAPTOPETALUM PARAGUAYENSE//3 HYDROXYL 3 METHYLGLUTAROYL HMG

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