Class information for:
Level 2: NNRTIS//REVERSE TRANSCRIPTASE//HIV DRUG ISTANCE PROGRAM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2356 4364 42.3 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
29 3       HIV//VIROLOGY//HIV 1 108954
2356 2             NNRTIS//REVERSE TRANSCRIPTASE//HIV DRUG ISTANCE PROGRAM 4364
1509 1                   NNRTIS//REVERSE TRANSCRIPTASE//HIV 1 REVERSE TRANSCRIPTASE 2619
5490 1                   NCP7//RNA DIMERIZATION//NUCLEOCAPSID PROTEIN 1617
33146 1                   3 METHYL 1 6 METHYL 2 METHYLSULFANYLPYRIMIDIN 4 YL 4 PHENYLIMINOMETHYL 1H PYRAZOL 5 OL//5 ALKYL OR ARYLTHIO 6 VINYL URACILS//5 BENZYLPYRIMIDIN 2 4 6 TRIONES 128

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NNRTIS authKW 794278 5% 53% 215
2 REVERSE TRANSCRIPTASE authKW 599364 8% 25% 346
3 HIV DRUG ISTANCE PROGRAM address 360101 4% 30% 173
4 HIV 1 REVERSE TRANSCRIPTASE authKW 267316 2% 45% 85
5 NCP7 authKW 132151 1% 82% 23
6 RNA DIMERIZATION authKW 128532 0% 88% 21
7 NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS authKW 128257 2% 27% 68
8 NUCLEOCAPSID PROTEIN authKW 127497 2% 24% 77
9 HIV 1 authKW 123860 9% 5% 385
10 REGA MED address 122213 5% 8% 232

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Virology 51455 26% 1% 1146
2 Chemistry, Medicinal 11354 16% 0% 681
3 Biochemistry & Molecular Biology 10804 42% 0% 1853
4 Chemistry, Organic 1189 9% 0% 393
5 Pharmacology & Pharmacy 866 11% 0% 468
6 Biophysics 593 5% 0% 232
7 Infectious Diseases 249 3% 0% 133
8 Biochemical Research Methods 120 3% 0% 120
9 Microbiology 106 4% 0% 157
10 Computer Science, Interdisciplinary Applications 62 2% 0% 74

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HIV DRUG ISTANCE PROGRAM 360101 4% 30% 173
2 REGA MED 122213 5% 8% 232
3 MCGILL AIDS 99897 1% 28% 51
4 RT BIOCHEM SECT 78140 0% 62% 18
5 ISTANCE MECH 69535 0% 76% 13
6 AIDS VACCINE PROGRAM 68062 1% 19% 51
7 ORETRO 63773 1% 40% 23
8 REVERSE TRANSCRIPTASE BIOCHEM SECT 51507 0% 82% 9
9 VIROL DRUG DISCOVERY 41971 0% 100% 6
10 PHARMACOCHIM MOL STRUCT 36056 1% 20% 26

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF VIROLOGY 50992 12% 1% 539
2 ANTIVIRAL CHEMISTRY & CHEMOTHERAPY 27279 1% 9% 44
3 JOURNAL OF MEDICINAL CHEMISTRY 11275 4% 1% 188
4 RETROVIROLOGY 10563 1% 4% 43
5 JOURNAL OF MOLECULAR BIOLOGY 8952 4% 1% 175
6 VIROLOGY 6365 3% 1% 132
7 BIOCHEMISTRY 5712 5% 0% 214
8 NUCLEIC ACIDS RESEARCH 5600 4% 0% 182
9 ANTIVIRAL RESEARCH 4380 1% 1% 47
10 BIOORGANIC & MEDICINAL CHEMISTRY 3936 2% 1% 87

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NNRTIS 794278 5% 53% 215 Search NNRTIS Search NNRTIS
2 REVERSE TRANSCRIPTASE 599364 8% 25% 346 Search REVERSE+TRANSCRIPTASE Search REVERSE+TRANSCRIPTASE
3 HIV 1 REVERSE TRANSCRIPTASE 267316 2% 45% 85 Search HIV+1+REVERSE+TRANSCRIPTASE Search HIV+1+REVERSE+TRANSCRIPTASE
4 NCP7 132151 1% 82% 23 Search NCP7 Search NCP7
5 RNA DIMERIZATION 128532 0% 88% 21 Search RNA+DIMERIZATION Search RNA+DIMERIZATION
6 NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS 128257 2% 27% 68 Search NON+NUCLEOSIDE+REVERSE+TRANSCRIPTASE+INHIBITORS Search NON+NUCLEOSIDE+REVERSE+TRANSCRIPTASE+INHIBITORS
7 NUCLEOCAPSID PROTEIN 127497 2% 24% 77 Search NUCLEOCAPSID+PROTEIN Search NUCLEOCAPSID+PROTEIN
8 HIV 1 123860 9% 5% 385 Search HIV+1 Search HIV+1
9 REVERSE TRANSCRIPTION 120984 2% 17% 101 Search REVERSE+TRANSCRIPTION Search REVERSE+TRANSCRIPTION
10 S DABOS 111923 0% 100% 16 Search S+DABOS Search S+DABOS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LEVIN, JG , GUO, JH , ROUZINA, I , MUSIER-FORSYTH, K , (2005) NUCLEIC ACID CHAPERONE ACTIVITY OF HIV-1 NUCLEOCAPSID PROTEIN: CRITICAL ROLE IN REVERSE TRANSCRIPTION AND MOLECULAR MECHANISM.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 80. VOL. 80. ISSUE . P. 217 -286 308 83% 228
2 ZHAN, P , CHEN, XW , LI, DY , FANG, ZJ , DE CLERCQ, E , LIU, XY , (2013) HIV-1 NNRTIS: STRUCTURAL DIVERSITY, PHARMACOPHORE SIMILARITY, AND IMPLIATIONS FOR DRUG DESIGN.MEDICINAL RESEARCH REVIEWS. VOL. 33. ISSUE . P. E1-E72 216 67% 32
3 LU, K , HENG, X , SUMMERS, MF , (2011) STRUCTURAL DETERMINANTS AND MECHANISM OF HIV-1 GENOME PACKAGING.JOURNAL OF MOLECULAR BIOLOGY. VOL. 410. ISSUE 4. P. 609-633 185 73% 89
4 LEVIN, JG , MITRA, M , MASCARENHAS, A , MUSIER-FORSYTH, K , (2010) ROLE OF HIV-1 NUCLEOCAPSID PROTEIN IN HIV-1 REVERSE TRANSCRIPTION.RNA BIOLOGY. VOL. 7. ISSUE 6. P. 754 -774 178 75% 49
5 BASU, VP , SONG, M , GAO, L , RIGBY, ST , HANSON, MN , BAMBARA, RA , (2008) STRAND TRANSFER EVENTS DURING HIV-1 REVERSE TRANSCRIPTION.VIRUS RESEARCH. VOL. 134. ISSUE 1-2. P. 19-38 148 94% 61
6 DARLIX, JL , DE ROCQUIGNY, H , MAUFFRET, O , MELY, Y , (2014) RETROSPECTIVE ON THE ALL-IN-ONE RETROVIRAL NUCLEOCAPSID PROTEIN.VIRUS RESEARCH. VOL. 193. ISSUE . P. 2 -15 176 68% 6
7 MORI, M , KOVALENKO, L , LYONNAIS, S , ANTAKI, D , TORBETT, BE , BOTTA, M , MIRAMBEAU, G , MELY, Y , (2015) NUCLEOCAPSID PROTEIN: A DESIRABLE TARGET FOR FUTURE THERAPIES AGAINST HIV-1.FUTURE OF HIV-1 THERAPEUTICS: RESISTANCE IS FUTILE?. VOL. 389. ISSUE . P. 53 -92 134 78% 8
8 D'SOUZA, V , SUMMERS, MF , (2005) HOW RETROVIRUSES SELECT THEIR GENOMES.NATURE REVIEWS MICROBIOLOGY. VOL. 3. ISSUE 8. P. 643-655 133 86% 180
9 ALI, LM , RIZVI, TA , MUSTAFA, F , (2016) CROSS- AND CO-PACKAGING OF RETROVIRAL RNAS AND THEIR CONSEQUENCES.VIRUSES-BASEL. VOL. 8. ISSUE 10. P. - 150 71% 0
10 SCHULTZ, SJ , CHAMPOUX, JJ , (2008) RNASE H ACTIVITY: STRUCTURE, SPECIFICITY, AND FUNCTION IN REVERSE TRANSCRIPTION.VIRUS RESEARCH. VOL. 134. ISSUE 1-2. P. 86-103 131 86% 53

Classes with closest relation at Level 2


Rank Class id link
1 773 EFAVIRENZ//NEVIRAPINE//RALTEGRAVIR
2 1825 INTEGRASE//VPR//APOBEC3G
3 636 ENDOGENOUS RETROVIRUS//RETROVIRUS//RETROVIRAL VECTOR
4 793 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//NUCLEOSIDES//CARBOCYCLIC NUCLEOSIDES
5 10 AIDS RESEARCH AND HUMAN RETROVIRUSES//VIROLOGY//HIV 1
6 1185 RIBOZYME//RNASE P//CATALYTIC RNA
7 1269 JOURNAL OF CHEMICAL INFORMATION AND MODELING//LIFE SCI INFORMAT//B IT
8 160 WERNER SYNDROME//DNA POLYMERASE//DNA REPAIR
9 2105 QUINOXALINE//1 5 BENZODIAZEPINES//1 5 BENZOTHIAZEPINE
10 1068 WIENER INDEX//QSAR//MATCH-COMMUNICATIONS IN MATHEMATICAL AND IN COMPUTER CHEMISTRY

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