Class information for:
Level 2: ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1078 9913 35.8 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
668 3       ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
1078 2             ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
463 1                   ENDOTHELIN//ENDOTHELIN RECEPTORS//SARAFOTOXIN 3406
496 1                   ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 3371
10613 1                   ENDOTHELIN 1//ENDOTHELIN//BQ 123 1048
14477 1                   ENDOTHELIN CONVERTING ENZYME//NEPRILYSIN//PHOSPHORAMIDON 767
16384 1                   MOL PATHOL ULTRASTRUCT//ENDOTHELIN AXIS//ZIBOTENTAN 656
24870 1                   LONGEV SCI//OSTEOBLAST//HOSP GERIATR MED 299
27763 1                   EXPT VASC//WNC//CLIN EXPT 222
32051 1                   CD10//CD10 EXPRESSION//BIOPATHOLUMR 599 144

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ENDOTHELIN authKW 3573294 24% 49% 2374
2 ENDOTHELIN 1 authKW 1882930 16% 39% 1572
3 ENDOTHELIN RECEPTORS authKW 1007927 5% 69% 474
4 BQ 123 authKW 538362 2% 77% 226
5 ETB RECEPTOR authKW 503446 2% 81% 201
6 ENDOTHELIN CONVERTING ENZYME authKW 499186 2% 75% 215
7 ETA RECEPTOR authKW 423028 2% 74% 185
8 ENDOTHELIN RECEPTOR ANTAGONIST authKW 255467 2% 41% 204
9 ENDOTHELIN 3 authKW 239651 1% 64% 121
10 SARAFOTOXIN S6C authKW 224398 1% 90% 81

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 23942 30% 0% 2968
2 Cardiac & Cardiovascular System 16959 17% 0% 1701
3 Peripheral Vascular Diseases 10257 10% 0% 997
4 Physiology 7227 10% 0% 1005
5 Medicine, Research & Experimental 2828 7% 0% 734
6 Endocrinology & Metabolism 2105 7% 0% 676
7 Urology & Nephrology 1657 5% 0% 447
8 Biophysics 1302 5% 0% 520
9 Biochemistry & Molecular Biology 1158 14% 0% 1342
10 Respiratory System 959 3% 0% 314

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPT VASC 133838 1% 49% 88
2 MOL PATHOL ULTRASTRUCT 76950 0% 83% 30
3 MOL NEUROBIOL PAIN 18853 0% 88% 7
4 STRUCT BIOINFORMAT UNIT 14285 0% 39% 12
5 CLIN EXPT 13943 0% 11% 43
6 WNC 13850 0% 75% 6
7 TRANSLAT FUNCT AREA 12825 0% 83% 5
8 PROTEOLYT NEUROSCI 12417 0% 16% 26
9 BIOENGN NEUROL REHABIL MED 12314 0% 100% 4
10 LONGEV SCI 11323 0% 12% 32

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 210233 9% 8% 867
2 BRITISH JOURNAL OF PHARMACOLOGY 17441 3% 2% 321
3 EUROPEAN JOURNAL OF PHARMACOLOGY 12998 4% 1% 351
4 HYPERTENSION 10413 2% 2% 200
5 LIFE SCIENCES 6456 2% 1% 211
6 CLINICAL SCIENCE 5660 1% 2% 111
7 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 4692 3% 1% 338
8 EXPERIMENTAL BIOLOGY AND MEDICINE 4115 1% 2% 60
9 PULMONARY PHARMACOLOGY & THERAPEUTICS 3431 0% 3% 41
10 JOURNAL OF HYPERTENSION 3330 1% 1% 105

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 ENDOTHELIN 3573294 24% 49% 2374 Search ENDOTHELIN Search ENDOTHELIN
2 ENDOTHELIN 1 1882930 16% 39% 1572 Search ENDOTHELIN+1 Search ENDOTHELIN+1
3 ENDOTHELIN RECEPTORS 1007927 5% 69% 474 Search ENDOTHELIN+RECEPTORS Search ENDOTHELIN+RECEPTORS
4 BQ 123 538362 2% 77% 226 Search BQ+123 Search BQ+123
5 ETB RECEPTOR 503446 2% 81% 201 Search ETB+RECEPTOR Search ETB+RECEPTOR
6 ENDOTHELIN CONVERTING ENZYME 499186 2% 75% 215 Search ENDOTHELIN+CONVERTING+ENZYME Search ENDOTHELIN+CONVERTING+ENZYME
7 ETA RECEPTOR 423028 2% 74% 185 Search ETA+RECEPTOR Search ETA+RECEPTOR
8 ENDOTHELIN RECEPTOR ANTAGONIST 255467 2% 41% 204 Search ENDOTHELIN+RECEPTOR+ANTAGONIST Search ENDOTHELIN+RECEPTOR+ANTAGONIST
9 ENDOTHELIN 3 239651 1% 64% 121 Search ENDOTHELIN+3 Search ENDOTHELIN+3
10 SARAFOTOXIN S6C 224398 1% 90% 81 Search SARAFOTOXIN+S6C Search SARAFOTOXIN+S6C

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RUBANYI, GM , POLOKOFF, MA , (1994) ENDOTHELINS - MOLECULAR-BIOLOGY, BIOCHEMISTRY, PHARMACOLOGY, PHYSIOLOGY, AND PATHOPHYSIOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 46. ISSUE 3. P. 325 -415 806 84% 1468
2 DAVENPORT, AP , HYNDMAN, KA , DHAUN, N , SOUTHAN, C , KOHAN, DE , POLLOCK, JS , POLLOCK, DM , WEBB, DJ , MAGUIRE, JJ , (2016) ENDOTHELIN.PHARMACOLOGICAL REVIEWS. VOL. 68. ISSUE 2. P. 357 -418 435 73% 11
3 KOHAN, DE , ROSSI, NF , INSCHO, EW , POLLOCK, DM , (2011) REGULATION OF BLOOD PRESSURE AND SALT HOMEOSTASIS BY ENDOTHELIN.PHYSIOLOGICAL REVIEWS. VOL. 91. ISSUE 1. P. 1 -77 581 69% 119
4 SIMONSON, MS , (1993) ENDOTHELINS - MULTIFUNCTIONAL RENAL PEPTIDES.PHYSIOLOGICAL REVIEWS. VOL. 73. ISSUE 2. P. 375-411 356 81% 262
5 MOTTE, S , MCENTEE, K , NAEIJE, R , (2006) ENDOTHELIN RECEPTOR ANTAGONISTS.PHARMACOLOGY & THERAPEUTICS. VOL. 110. ISSUE 3. P. 386-414 280 76% 102
6 GRAY, GA , WEBB, DJ , (1996) THE ENDOTHELIN SYSTEM AND ITS POTENTIAL AS A THERAPEUTIC TARGET IN CARDIOVASCULAR DISEASE.PHARMACOLOGY & THERAPEUTICS. VOL. 72. ISSUE 2. P. 109 -148 338 84% 99
7 HUGGINS, JP , PELTON, JT , MILLER, RC , (1993) THE STRUCTURE AND SPECIFICITY OF ENDOTHELIN RECEPTORS - THEIR IMPORTANCE IN PHYSIOLOGY AND MEDICINE.PHARMACOLOGY & THERAPEUTICS. VOL. 59. ISSUE 1. P. 55-123 336 86% 173
8 KOHAN, DE , INSCHO, EW , WESSON, D , POLLOCK, DM , (2011) PHYSIOLOGY OF ENDOTHELIN AND THE KIDNEY.COMPREHENSIVE PHYSIOLOGY. VOL. 1. ISSUE 2. P. 883 -919 311 63% 13
9 BATTISTINI, B , DORLEANSJUSTE, P , SIROIS, P , (1993) ENDOTHELINS - CIRCULATING PLASMA-LEVELS AND PRESENCE IN OTHER BIOLOGIC FLUIDS.LABORATORY INVESTIGATION. VOL. 68. ISSUE 6. P. 600-628 313 88% 206
10 MICHAEL, JR , MARKEWITZ, BA , (1996) ENDOTHELINS AND THE LUNG.AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. VOL. 154. ISSUE 3. P. 555-581 326 77% 151

Classes with closest relation at Level 2


Rank Class id link
1 197 ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE
2 484 PULMONARY HYPERTENSION//PULMONARY ARTERIAL HYPERTENSION//CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
3 2182 SUBARACHNOID HEMORRHAGE//CEREBRAL VASOSPASM//VASOSPASM
4 1611 HEPATOPULMONARY SYNDROME//SPONTANEOUS BACTERIAL PERITONITIS//CIRRHOSIS
5 1415 DIPEPTIDYL PEPTIDASE IV//CD26//AMINOPEPTIDASE
6 2998 RGS PROTEINS//GIRDIN//RGS
7 934 NATRIURETIC PEPTIDES//ATRIAL NATRIURETIC PEPTIDE//BRAIN NATRIURETIC PEPTIDE
8 3735 UROTENSIN II//GPR14//UT RECEPTOR
9 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
10 938 CARDIAC HYPERTROPHY//HYPERTROPHY//CARDIOTROPHIN 1

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