Class information for:
Level 1: ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR//EDHF//ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4694 1742 43.4 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
197 2             ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE 21389
4694 1                   ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR//EDHF//ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF 1742

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR authKW 1786723 12% 48% 213
2 EDHF authKW 1477369 9% 54% 155
3 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF authKW 313602 2% 62% 29
4 HYPERPOLARIZATION authKW 221625 5% 14% 89
5 ENDOTHELIUM authKW 143502 19% 2% 337
6 ENDOTHELIUM DEPENDENT HYPERPOLARIZATION authKW 128775 1% 57% 13
7 CONDUCTED VASODILATION authKW 125188 1% 71% 10
8 POTASSIUM CHANNELS authKW 109392 9% 4% 164
9 CONDUCTED RESPONSE authKW 102127 1% 45% 13
10 CALCIUM ACTIVATED POTASSIUM CHANNELS authKW 98140 2% 14% 41

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 16797 34% 0% 591
2 Peripheral Vascular Diseases 14783 27% 0% 475
3 Cardiac & Cardiovascular System 5889 24% 0% 410
4 Pharmacology & Pharmacy 5504 34% 0% 589
5 Hematology 862 8% 0% 131
6 Cell Biology 145 7% 0% 118
7 Neurosciences 126 8% 0% 133
8 Biophysics 41 3% 0% 51
9 Medicine, Research & Experimental 28 3% 0% 48
10 Biochemistry & Molecular Biology 13 8% 0% 132

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SMOOTH MUSCLE GRP 62046 2% 11% 32
2 JOHN B PIERCE 39237 1% 13% 17
3 MEDBIOHLTH PROD 35054 0% 100% 2
4 PANUM 10 5 35054 0% 100% 2
5 PHARMACOL GRPQUEENS MED 35054 0% 100% 2
6 DIABET MALAD METAB 28039 0% 40% 4
7 HOTCHKISS BRAIN LIBIN CARDIOVASC 26288 0% 50% 3
8 AC BURTON 23368 0% 67% 2
9 PHYSIOL PHYSIOPATHOL 22072 1% 11% 11
10 WALES HEART 21327 1% 6% 22

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRITISH JOURNAL OF PHARMACOLOGY 43192 12% 1% 209
2 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 41746 10% 1% 172
3 MICROCIRCULATION 21199 2% 3% 36
4 JOURNAL OF VASCULAR RESEARCH 18828 2% 3% 36
5 JOURNAL OF PHYSIOLOGY-LONDON 9854 6% 1% 102
6 CIRCULATION RESEARCH 6175 3% 1% 60
7 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 4745 3% 1% 55
8 VASCULAR PHARMACOLOGY 4457 1% 2% 17
9 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 4245 3% 1% 45
10 EUROPEAN JOURNAL OF PHARMACOLOGY 2624 4% 0% 66

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR 1786723 12% 48% 213 Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR
2 EDHF 1477369 9% 54% 155 Search EDHF Search EDHF
3 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF 313602 2% 62% 29 Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR+EDHF Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR+EDHF
4 HYPERPOLARIZATION 221625 5% 14% 89 Search HYPERPOLARIZATION Search HYPERPOLARIZATION
5 ENDOTHELIUM 143502 19% 2% 337 Search ENDOTHELIUM Search ENDOTHELIUM
6 ENDOTHELIUM DEPENDENT HYPERPOLARIZATION 128775 1% 57% 13 Search ENDOTHELIUM+DEPENDENT+HYPERPOLARIZATION Search ENDOTHELIUM+DEPENDENT+HYPERPOLARIZATION
7 CONDUCTED VASODILATION 125188 1% 71% 10 Search CONDUCTED+VASODILATION Search CONDUCTED+VASODILATION
8 POTASSIUM CHANNELS 109392 9% 4% 164 Search POTASSIUM+CHANNELS Search POTASSIUM+CHANNELS
9 CONDUCTED RESPONSE 102127 1% 45% 13 Search CONDUCTED+RESPONSE Search CONDUCTED+RESPONSE
10 CALCIUM ACTIVATED POTASSIUM CHANNELS 98140 2% 14% 41 Search CALCIUM+ACTIVATED+POTASSIUM+CHANNELS Search CALCIUM+ACTIVATED+POTASSIUM+CHANNELS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GARLAND, CJ , DORA, KA , (2017) EDH: ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION AND MICROVASCULAR SIGNALLING.ACTA PHYSIOLOGICA. VOL. 219. ISSUE 1. P. 152 -161 65 87% 7
2 GRIFFITH, TM , (2004) ENDOTHELIUM-DEPENDENT SMOOTH MUSCLE HYPERPOLARIZATION: DO GAP JUNCTIONS PROVIDE A UNIFYING HYPOTHESIS?.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 141. ISSUE 6. P. 881-903 179 63% 156
3 DE WIT, C , GRIFFITH, TM , (2010) CONNEXINS AND GAP JUNCTIONS IN THE EDHF PHENOMENON AND CONDUCTED VASOMOTOR RESPONSES.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 459. ISSUE 6. P. 897 -914 134 64% 70
4 DE WIT, C , WOLFLE, SE , (2007) EDHF AND GAP JUNCTIONS: IMPORTANT REGULATORS OF VASCULAR TONE WITHIN THE MICROCIRCULATION.CURRENT PHARMACEUTICAL BIOTECHNOLOGY. VOL. 8. ISSUE 1. P. 11 -25 149 68% 36
5 BRYAN, RM , YOU, JP , GOLDING, EM , MARRELLI, SP , (2005) ENDOTHELIUM-DERIVED HYPERPOLARIZING FACTOR - A COUSIN TO NITRIC OXIDE AND PROSTACYCLIN.ANESTHESIOLOGY. VOL. 102. ISSUE 6. P. 1261-1277 142 57% 73
6 FELETOU, M , VANHOUTTE, PM , (2007) ENDOTHELIUM-DEPENDENT HYPERPOLARIZATIONS: PAST BELIEFS AND PRESENT FACTS.ANNALS OF MEDICINE. VOL. 39. ISSUE 7. P. 495-516 127 59% 68
7 FELETOU, M , (2016) ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION AND ENDOTHELIAL DYSFUNCTION.JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. VOL. 67. ISSUE 5. P. 373 -387 116 52% 1
8 BUSSE, R , EDWARDS, G , FELETOU, M , FLEMING, I , VANHOUTTE, PM , WESTON, AH , (2002) EDHF: BRINGING THE CONCEPTS TOGETHER.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 23. ISSUE 8. P. 374 -380 64 84% 518
9 LEUNG, SWS , VANHOUTTE, PM , (2017) ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION: AGE, GENDER AND BLOOD PRESSURE, DO THEY MATTER?.ACTA PHYSIOLOGICA. VOL. 219. ISSUE 1. P. 108 -123 76 47% 1
10 LUKSHA, L , AGEWALL, S , KUBLICKIENE, K , (2009) ENDOTHELIUM-DERIVED HYPERPOLARIZING FACTOR IN VASCULAR PHYSIOLOGY AND CARDIOVASCULAR DISEASE.ATHEROSCLEROSIS. VOL. 202. ISSUE 2. P. 330-344 104 57% 67

Classes with closest relation at Level 1


Rank Class id link
1 20881 ENDOTHELIUM DEPENDENT CONTRACTION//ENDOTHELIUM DERIVED CONTRACTING FACTOR//THROMBOXANE PROSTANOID RECEPTOR
2 3828 ENDOTHELIUM DERIVED RELAXING FACTOR//EDRF//N G NITRO L ARGININE
3 26242 VASOMOTION//RHYTHMIC CONTRACTIONS//VASOMOTION PATTERNS
4 8162 EXERCISE HYPEREMIA//MUSCLE BLOOD FLOW//HUMAN CARDIOVASC PHYSIOL
5 12971 MYOGENIC RESPONSE//MYOGENIC TONE//MICROVASC BIOL GRP
6 13424 HYPOXIC PULMONARY VASOCONSTRICTION//VOLTAGE DEPENDENT K CHANNEL//OXIDATIVE DNA MODIFICATIONS
7 9930 PHYSIOL MORPHOL//RAT AORTAE//DIABETES
8 2000 EPOXYEICOSATRIENOIC ACIDS//SOLUBLE EPOXIDE HYDROLASE//20 HYDROXYEICOSATETRAENOIC ACID
9 12462 SK CHANNELS//APAMIN//AFTERHYPERPOLARIZATION
10 28494 RODENT MODELS OF OBESITY//RODENT MODELS OF METABOLIC SYNDROME//REGULATION OF SKELETAL MUSCLE BLOOD FLOW

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