Class information for:
Level 1: ENDOTHELIUM DEPENDENT CONTRACTION//ENDOTHELIUM DERIVED CONTRACTING FACTOR//THROMBOXANE PROSTANOID RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20881 442 48.0 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
197 2             ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE 21389
20881 1                   ENDOTHELIUM DEPENDENT CONTRACTION//ENDOTHELIUM DERIVED CONTRACTING FACTOR//THROMBOXANE PROSTANOID RECEPTOR 442

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOTHELIUM DEPENDENT CONTRACTION authKW 1351614 7% 65% 30
2 ENDOTHELIUM DERIVED CONTRACTING FACTOR authKW 469281 6% 27% 25
3 THROMBOXANE PROSTANOID RECEPTOR authKW 452173 3% 55% 12
4 TP RECEPTORS authKW 207239 2% 33% 9
5 PROSTAGLANDIN H 2 authKW 159866 2% 26% 9
6 DIABETE MALAD METAB address 155437 1% 75% 3
7 EDCF authKW 146971 2% 21% 10
8 CAROTID BALLOON INJURY authKW 138167 0% 100% 2
9 CONTRALATERAL CAROTID authKW 138167 0% 100% 2
10 ENDOTHELIUM DERIVED COX 1 METABOLITES authKW 138167 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 3344 26% 0% 114
2 Pharmacology & Pharmacy 2433 44% 0% 193
3 Physiology 1644 21% 0% 95
4 Cardiac & Cardiovascular System 1149 21% 0% 92
5 Endocrinology & Metabolism 58 6% 0% 25
6 Medicine, Research & Experimental 52 5% 0% 23
7 Hematology 13 2% 0% 11
8 Biochemistry & Molecular Biology 11 9% 0% 41
9 Cell Biology 9 5% 0% 20
10 Integrative & Complementary Medicine 9 1% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABETE MALAD METAB 155437 1% 75% 3
2 CLIN ATHEROSCLEROSIS 77715 1% 38% 3
3 JIANGSU PROVINCE HOSP 77715 1% 38% 3
4 ANAT PATHOL 1 69084 0% 100% 1
5 BIOINGNINSIBIO 69084 0% 100% 1
6 CLIN IMMUNOL IMMUNOL MICROBIOL 69084 0% 100% 1
7 HLTH LA PAZ UNIV HOSP IDIPAZ 69084 0% 100% 1
8 INSERMESPRI EA 3745 69084 0% 100% 1
9 INTEGRAT PHYSIOL ANAT OBSTET GYNECOL 69084 0% 100% 1
10 INTERNALIZAT 69084 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRITISH JOURNAL OF PHARMACOLOGY 8970 11% 0% 48
2 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 7195 8% 0% 36
3 HYPERTENSION 3738 6% 0% 25
4 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 2490 5% 0% 20
5 EUROPEAN JOURNAL OF PHARMACOLOGY 2489 7% 0% 32
6 JOURNAL OF HYPERTENSION 1810 4% 0% 16
7 FREE RADICAL BIOLOGY AND MEDICINE 1558 3% 0% 14
8 VASCULAR PHARMACOLOGY 972 1% 0% 4
9 ACTA PHARMACOLOGICA SINICA 772 2% 0% 8
10 BLOOD VESSELS 685 0% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTHELIUM DEPENDENT CONTRACTION 1351614 7% 65% 30 Search ENDOTHELIUM+DEPENDENT+CONTRACTION Search ENDOTHELIUM+DEPENDENT+CONTRACTION
2 ENDOTHELIUM DERIVED CONTRACTING FACTOR 469281 6% 27% 25 Search ENDOTHELIUM+DERIVED+CONTRACTING+FACTOR Search ENDOTHELIUM+DERIVED+CONTRACTING+FACTOR
3 THROMBOXANE PROSTANOID RECEPTOR 452173 3% 55% 12 Search THROMBOXANE+PROSTANOID+RECEPTOR Search THROMBOXANE+PROSTANOID+RECEPTOR
4 TP RECEPTORS 207239 2% 33% 9 Search TP+RECEPTORS Search TP+RECEPTORS
5 PROSTAGLANDIN H 2 159866 2% 26% 9 Search PROSTAGLANDIN+H+2 Search PROSTAGLANDIN+H+2
6 EDCF 146971 2% 21% 10 Search EDCF Search EDCF
7 CAROTID BALLOON INJURY 138167 0% 100% 2 Search CAROTID+BALLOON+INJURY Search CAROTID+BALLOON+INJURY
8 CONTRALATERAL CAROTID 138167 0% 100% 2 Search CONTRALATERAL+CAROTID Search CONTRALATERAL+CAROTID
9 ENDOTHELIUM DERIVED COX 1 METABOLITES 138167 0% 100% 2 Search ENDOTHELIUM+DERIVED+COX+1+METABOLITES Search ENDOTHELIUM+DERIVED+COX+1+METABOLITES
10 CONTRALATERAL CAROTID ARTERY 92110 0% 67% 2 Search CONTRALATERAL+CAROTID+ARTERY Search CONTRALATERAL+CAROTID+ARTERY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VANHOUTTE, PM , (2011) ENDOTHELIUM-DEPENDENT CONTRACTIONS IN HYPERTENSION WHEN PROSTACYCLIN BECOMES UGLY.HYPERTENSION. VOL. 57. ISSUE 3. P. 526 -531 45 48% 30
2 TANG, EHC , VANHOUTTE, PM , (2009) PROSTANOIDS AND REACTIVE OXYGEN SPECIES: TEAM PLAYERS IN ENDOTHELIUM-DEPENDENT CONTRACTIONS.PHARMACOLOGY & THERAPEUTICS. VOL. 122. ISSUE 2. P. 140-149 45 49% 45
3 VANHOUTTE, PM , SHIMOKAWA, H , FELETOU, M , TANG, EHC , (2017) ENDOTHELIAL DYSFUNCTION AND VASCULAR DISEASE - A 30TH ANNIVERSARY UPDATE.ACTA PHYSIOLOGICA. VOL. 219. ISSUE 1. P. 22 -96 76 8% 6
4 LUO, WH , LIU, B , ZHOU, YB , (2016) THE ENDOTHELIAL CYCLOOXYGENASE PATHWAY: INSIGHTS FROM MOUSE ARTERIES.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 780. ISSUE . P. 148 -158 42 39% 2
5 VANHOUTTE, PM , TANG, EHC , (2008) ENDOTHELIUM-DEPENDENT CONTRACTIONS: WHEN A GOOD GUY TURNS BAD!.JOURNAL OF PHYSIOLOGY-LONDON. VOL. 586. ISSUE 22. P. 5295 -5304 45 44% 61
6 LIU, B , LI, ZH , ZHANG, YZ , LUO, WH , ZHANG, JL , LI, H , ZHOU, YB , (2015) VASOMOTOR REACTION TO CYCLOOXYGENASE-1-MEDIATED PROSTACYCLIN SYNTHESIS IN CAROTID ARTERIES FROM TWO-KIDNEY-ONE-CLIP HYPERTENSIVE MICE.PLOS ONE. VOL. 10. ISSUE 8. P. - 29 62% 1
7 LI, ZH , ZHANG, YZ , LIU, B , LUO, WH , LI, H , ZHOU, YB , (2017) ROLE OF E-TYPE PROSTAGLANDIN RECEPTOR EP3 IN THE VASOCONSTRICTOR ACTIVITY EVOKED BY PROSTACYCLIN IN THROMBOXANE-PROSTANOID RECEPTOR DEFICIENT MICE.SCIENTIFIC REPORTS. VOL. 7. ISSUE . P. - 29 58% 0
8 TANG, EHC , VANHOUTTE, PM , (2010) ENDOTHELIAL DYSFUNCTION: A STRATEGIC TARGET IN THE TREATMENT OF HYPERTENSION?.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 459. ISSUE 6. P. 995 -1004 39 43% 59
9 WONG, MSK , VANHOUTTE, PM , (2010) COX-MEDIATED ENDOTHELIUM-DEPENDENT CONTRACTIONS: FROM THE PAST TO RECENT DISCOVERIES.ACTA PHARMACOLOGICA SINICA. VOL. 31. ISSUE 9. P. 1095-1102 39 42% 35
10 LI, SS , LIU, B , LUO, WH , ZHANG, YZ , LI, H , HUANG, DY , ZHOU, YB , (2016) ROLE OF CYCLOOXYGENASE-1 AND-2 IN ENDOTHELIUM-DEPENDENT CONTRACTION OF ATHEROSCLEROTIC MOUSE ABDOMINAL AORTAS.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. VOL. 43. ISSUE 1. P. 67 -74 25 51% 1

Classes with closest relation at Level 1


Rank Class id link
1 4694 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR//EDHF//ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF
2 3828 ENDOTHELIUM DERIVED RELAXING FACTOR//EDRF//N G NITRO L ARGININE
3 9930 PHYSIOL MORPHOL//RAT AORTAE//DIABETES
4 28494 RODENT MODELS OF OBESITY//RODENT MODELS OF METABOLIC SYNDROME//REGULATION OF SKELETAL MUSCLE BLOOD FLOW
5 35753 NA DEPENDENT CA2 UPTAKE//TISSUE INHIBITOR OF METALLOPROTEASE 2//GIALPHA
6 18382 HUMAN FOREARM VASCULATURE//CGP 48369//ENDOTHELIUM
7 13424 HYPOXIC PULMONARY VASOCONSTRICTION//VOLTAGE DEPENDENT K CHANNEL//OXIDATIVE DNA MODIFICATIONS
8 20328 REYNOLDS OKLAHOMA AGING//VASCULAR AGING//DONALD W REYNOLDS GERIATR MED
9 19004 AGGREGATED PROTEIN//FRANCE HELLEN BIOMED//N 6 N 3 POLYUNSATURATED FATTY ACIDS
10 2397 NADPH OXIDASE//NOX4//NOX1

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