Class information for:
Level 1: MOL CARDIOBIOL PROGRAM//CARDIOVASC HYPERTENS//ENDOTHELIAL NITRIC OXIDE SYNTHASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20641 451 45.9 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
197 2             ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE 21389
20641 1                   MOL CARDIOBIOL PROGRAM//CARDIOVASC HYPERTENS//ENDOTHELIAL NITRIC OXIDE SYNTHASE 451

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL CARDIOBIOL PROGRAM address 248237 2% 33% 11
2 CARDIOVASC HYPERTENS address 203103 2% 33% 9
3 ENDOTHELIAL NITRIC OXIDE SYNTHASE authKW 179500 13% 4% 60
4 ENOS authKW 174922 12% 5% 54
5 DAVIS HEART LUNG 605 address 135410 0% 100% 2
6 ENOS MUTANTS authKW 135410 0% 100% 2
7 PEDIAT SURG PHARMACOL TOXICOL address 135410 0% 100% 2
8 PHOSPHORYLATION OF ENOS authKW 135410 0% 100% 2
9 DIS GRP CARDIOVASC AGENTS address 101554 1% 50% 3
10 NEPHROL HYPERTENS CARDIOVASC address 101554 1% 50% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 1607 18% 0% 81
2 Physiology 1207 18% 0% 83
3 Biochemistry & Molecular Biology 640 33% 0% 151
4 Cardiac & Cardiovascular System 600 15% 0% 69
5 Cell Biology 455 18% 0% 80
6 Hematology 224 8% 0% 34
7 Pharmacology & Pharmacy 146 13% 0% 58
8 Biophysics 61 5% 0% 24
9 Endocrinology & Metabolism 50 5% 0% 24
10 Medicine, Research & Experimental 44 5% 0% 22

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL CARDIOBIOL PROGRAM 248237 2% 33% 11
2 CARDIOVASC HYPERTENS 203103 2% 33% 9
3 DAVIS HEART LUNG 605 135410 0% 100% 2
4 PEDIAT SURG PHARMACOL TOXICOL 135410 0% 100% 2
5 DIS GRP CARDIOVASC AGENTS 101554 1% 50% 3
6 NEPHROL HYPERTENS CARDIOVASC 101554 1% 50% 3
7 VASC CELL SIGNALING THER EUT PROGRAM 101554 1% 50% 3
8 BOYER MOL MED PHARMACOL 90272 0% 67% 2
9 ADDENBROOKES HOSP CLIN MED MED 67705 0% 100% 1
10 ADDENBROOKES HOSP CLIN MED PATHOL 67705 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VASCULAR PHARMACOLOGY 5982 2% 1% 10
2 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 2861 5% 0% 23
3 NITRIC OXIDE-BIOLOGY AND CHEMISTRY 2425 2% 1% 7
4 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 1830 3% 0% 14
5 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 1758 3% 0% 14
6 CIRCULATION RESEARCH 1490 3% 0% 15
7 CARDIOVASCULAR RESEARCH 1230 3% 0% 12
8 JOURNAL OF BIOLOGICAL CHEMISTRY 1155 12% 0% 52
9 FREE RADICAL BIOLOGY AND MEDICINE 938 2% 0% 11
10 JOURNAL OF VASCULAR RESEARCH 893 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTHELIAL NITRIC OXIDE SYNTHASE 179500 13% 4% 60 Search ENDOTHELIAL+NITRIC+OXIDE+SYNTHASE Search ENDOTHELIAL+NITRIC+OXIDE+SYNTHASE
2 ENOS 174922 12% 5% 54 Search ENOS Search ENOS
3 ENOS MUTANTS 135410 0% 100% 2 Search ENOS+MUTANTS Search ENOS+MUTANTS
4 PHOSPHORYLATION OF ENOS 135410 0% 100% 2 Search PHOSPHORYLATION+OF+ENOS Search PHOSPHORYLATION+OF+ENOS
5 HELA TETOFF CELLS 90272 0% 67% 2 Search HELA+TETOFF+CELLS Search HELA+TETOFF+CELLS
6 NITRIC OXIDE CHEMILUMINESCENCE 90272 0% 67% 2 Search NITRIC+OXIDE+CHEMILUMINESCENCE Search NITRIC+OXIDE+CHEMILUMINESCENCE
7 6 STYRYL 2 PYRONE 67705 0% 100% 1 Search 6+STYRYL+2+PYRONE Search 6+STYRYL+2+PYRONE
8 ACYLATION CYCLE 67705 0% 100% 1 Search ACYLATION+CYCLE Search ACYLATION+CYCLE
9 ANIBA PANURENSIS 67705 0% 100% 1 Search ANIBA+PANURENSIS Search ANIBA+PANURENSIS
10 APHRODISIAC COMPOUND 67705 0% 100% 1 Search APHRODISIAC+COMPOUND Search APHRODISIAC+COMPOUND

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DUDZINSKI, DM , MICHEL, T , (2007) LIFE HISTORY OF ENOS: PARTNERS AND PATHWAYS.CARDIOVASCULAR RESEARCH. VOL. 75. ISSUE 2. P. 247-260 49 37% 216
2 MOUNT, PF , KEMP, BE , POWER, DA , (2007) REGULATION OF ENDOTHELIAL AND MYOCARDIAL NO SYNTHESIS BY MULTI-SITE ENOS PHOSPHORYLATION.JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. VOL. 42. ISSUE 2. P. 271 -279 34 49% 260
3 QIAN, J , FULTON, D , (2013) POST-TRANSLATIONAL REGULATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN VASCULAR ENDOTHELIUM.FRONTIERS IN PHYSIOLOGY. VOL. 4. ISSUE . P. - 55 31% 26
4 FLEMING, I , BUSSE, R , (2003) MOLECULAR MECHANISMS INVOLVED IN THE REGULATION OF THE ENDOTHELIAL NITRIC OXIDE SYNTHASE.AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. VOL. 284. ISSUE 1. P. R1-R12 43 32% 526
5 RAMADOSS, J , PASTORE, MB , MAGNESS, RR , (2013) ENDOTHELIAL CAVEOLAR SUBCELLULAR DOMAIN REGULATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE.CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. VOL. 40. ISSUE 11. P. 753-764 33 37% 6
6 HEISS, EH , DIRSCH, VM , (2014) REGULATION OF ENOS ENZYME ACTIVITY BY POSTTRANSLATIONAL MODIFICATION.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 22. P. 3503 -3513 33 32% 14
7 RUAN, L , TORRES, CM , BUFFETT, RJ , KENNARD, S , FULTON, D , VENEMA, RC , (2013) CALCINEURIN-MEDIATED DEPHOSPHORYLATION OF ENOS AT SERINE 116 AFFECTS ENOS ENZYMATIC ACTIVITY INDIRECTLY BY FACILITATING C-SRC BINDING AND TYROSINE 83 PHOSPHORYLATION.VASCULAR PHARMACOLOGY. VOL. 59. ISSUE 1-2. P. 27-35 19 63% 2
8 BAUER, PM , FULTON, D , BOO, YC , SORESCU, GP , KEMP, BE , JO, H , SESSA, WC , (2003) COMPENSATORY PHOSPHORYLATION AND PROTEIN-PROTEIN INTERACTIONS REVEALED BY LOSS OF FUNCTION AND GAIN OF FUNCTION MUTANTS OF MULTIPLE-SERINE PHOSPHORYLATION SITES IN ENDOTHELIAL NITRIC-OXIDE SYNTHASE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 278. ISSUE 17. P. 14841-14849 20 65% 143
9 HAINES, RJ , CORBIN, KD , PENDLETON, LC , EICHLER, DC , (2012) PROTEIN KINASE C ALPHA PHOSPHORYLATES A NOVEL ARGININOSUCCINATE SYNTHASE SITE AT SERINE 328 DURING CALCIUM-DEPENDENT STIMULATION OF ENDOTHELIAL NITRIC-OXIDE SYNTHASE IN VASCULAR ENDOTHELIAL CELLS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 31. P. 26168-26176 19 61% 4
10 TAYLOR, SY , DIXON, HM , YOGANAYAGAM, S , PRICE, N , LANG, D , (2013) FOLIC ACID MODULATES ENOS ACTIVITY VIA EFFECTS ON POSTTRANSLATIONAL MODIFICATIONS AND PROTEIN-PROTEIN INTERACTIONS.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 714. ISSUE 1-3. P. 193-201 24 45% 7

Classes with closest relation at Level 1


Rank Class id link
1 3477 NITRIC OXIDE SYNTHASE//MOL INNOVAT DRUG DISCOVERY//HEME REDUCTION
2 31160 VB 111//MOL VASC MED//ADV STUDIES PHARMACOBIOL
3 3782 SHEAR STRESS//HEMODYNAMIC FORCES//CYCLIC STRAIN
4 1830 CAVEOLIN 1//CAVEOLAE//CAVEOLIN
5 11184 NOS3//ENOS GENE//ENDOTHELIAL NITRIC OXIDE SYNTHASE
6 10907 NUTRITIVE FLOW//NON NUTRITIVE FLOW//INSULIN TRANSPORT
7 37211 EDF 1//MBF1//MULTIPROTEIN BRIDGING FACTOR 1 MBF1
8 15403 POLYASPARTOYL L ARGININE//BEIJING S HYDRONE PEPTIDES//PLATELETS
9 20328 REYNOLDS OKLAHOMA AGING//VASCULAR AGING//DONALD W REYNOLDS GERIATR MED
10 31719 ST EUGENIO CTO A ALESINI HOSP//MASSACHUSETTS GEN HOSPSHRINERS HOSP CHILDREN//ABLUMINAL MEMBRANE

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