Class information for:
Level 1: NADPH OXIDASE//NOX4//NOX1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2397 2259 59.0 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
197 2             ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE 21389
2397 1                   NADPH OXIDASE//NOX4//NOX1 2259

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NADPH OXIDASE authKW 2197064 33% 22% 748
2 NOX4 authKW 859230 5% 55% 115
3 NOX1 authKW 738788 4% 67% 82
4 APOCYNIN authKW 411108 4% 37% 82
5 P22PHOX authKW 309932 2% 46% 50
6 NOX5 authKW 216996 1% 94% 17
7 NOX2 authKW 176734 2% 30% 44
8 NOXA1 authKW 175700 1% 100% 13
9 KARDIOVASKULARE PHYSIOL address 172873 2% 35% 37
10 NOXO1 authKW 162185 1% 100% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Peripheral Vascular Diseases 9449 19% 0% 438
2 Biochemistry & Molecular Biology 3314 34% 0% 767
3 Endocrinology & Metabolism 2977 15% 0% 337
4 Cardiac & Cardiovascular System 2730 15% 0% 331
5 Cell Biology 1641 15% 0% 348
6 Hematology 1542 9% 0% 196
7 Physiology 1051 8% 0% 188
8 Medicine, Research & Experimental 278 5% 0% 120
9 Pharmacology & Pharmacy 257 9% 0% 200
10 Urology & Nephrology 81 3% 0% 57

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KARDIOVASKULARE PHYSIOL 172873 2% 35% 37
2 AUDIE L MURPHY MEM HOSP 50873 0% 47% 8
3 AUDIE LEON MURPHY MEM HOSP 40546 0% 100% 3
4 AUDIE MURPHY MEM VET ADM HOSP 40546 0% 100% 3
5 BIOL AGEING S 40546 0% 100% 3
6 NEPHROL MC 7882 40546 0% 100% 3
7 VET MOL BIOL 38289 1% 11% 27
8 WMB 319 30408 0% 75% 3
9 VASC ENDOTHELIUM MICROCIRCULAT 27567 0% 20% 10
10 BIOCHIM ENZYME PROT DBTP 27031 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIOXIDANTS & REDOX SIGNALING 67388 5% 4% 124
2 FREE RADICAL BIOLOGY AND MEDICINE 31198 6% 2% 141
3 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 10085 3% 1% 75
4 REDOX BIOLOGY 8208 1% 4% 17
5 ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH 6918 1% 4% 13
6 CIRCULATION RESEARCH 6656 3% 1% 71
7 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 3329 2% 0% 56
8 OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2855 1% 1% 19
9 CARDIOVASCULAR RESEARCH 2435 2% 0% 38
10 HYPERTENSION 2312 2% 0% 45

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NADPH OXIDASE 2197064 33% 22% 748 Search NADPH+OXIDASE Search NADPH+OXIDASE
2 NOX4 859230 5% 55% 115 Search NOX4 Search NOX4
3 NOX1 738788 4% 67% 82 Search NOX1 Search NOX1
4 APOCYNIN 411108 4% 37% 82 Search APOCYNIN Search APOCYNIN
5 P22PHOX 309932 2% 46% 50 Search P22PHOX Search P22PHOX
6 NOX5 216996 1% 94% 17 Search NOX5 Search NOX5
7 NOX2 176734 2% 30% 44 Search NOX2 Search NOX2
8 NOXA1 175700 1% 100% 13 Search NOXA1 Search NOXA1
9 NOXO1 162185 1% 100% 12 Search NOXO1 Search NOXO1
10 REACTIVE OXYGEN SPECIES 136451 20% 2% 457 Search REACTIVE+OXYGEN+SPECIES Search REACTIVE+OXYGEN+SPECIES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LASSEGUE, B , SAN MARTIN, A , GRIENDLING, KK , (2012) BIOCHEMISTRY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OF NADPH OXIDASES IN THE CARDIOVASCULAR SYSTEM.CIRCULATION RESEARCH. VOL. 110. ISSUE 10. P. 1364 -1390 249 66% 250
2 BEDARD, K , KRAUSE, KH , (2007) THE NOX FAMILY OF ROS-GENERATING NADPH OXIDASES: PHYSIOLOGY AND PATHOPHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 87. ISSUE 1. P. 245-313 241 26% 2431
3 BROWN, DI , GRIENDLING, KK , (2009) NOX PROTEINS IN SIGNAL TRANSDUCTION.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 47. ISSUE 9. P. 1239 -1253 136 68% 359
4 KONIOR, A , SCHRAMM, A , CZESNIKIEWICZ-GUZIK, M , GUZIK, TJ , (2014) NADPH OXIDASES IN VASCULAR PATHOLOGY.ANTIOXIDANTS & REDOX SIGNALING. VOL. 20. ISSUE 17. P. 2794 -2814 140 68% 66
5 ALTENHOFER, S , KLEIKERS, PWM , RADERMACHER, KA , SCHEURER, P , HERMANS, JJR , SCHIFFERS, P , HO, HD , WINGLER, K , SCHMIDT, HHHW , (2012) THE NOX TOOLBOX: VALIDATING THE ROLE OF NADPH OXIDASES IN PHYSIOLOGY AND DISEASE.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 69. ISSUE 14. P. 2327 -2343 129 71% 115
6 DRUMMOND, GR , SELEMIDIS, S , GRIENDLING, KK , SOBEY, CG , (2011) COMBATING OXIDATIVE STRESS IN VASCULAR DISEASE: NADPH OXIDASES AS THERAPEUTIC TARGETS.NATURE REVIEWS DRUG DISCOVERY. VOL. 10. ISSUE 6. P. 453 -471 124 57% 306
7 CHEN, F , HAIGH, S , BARMAN, S , FULTON, DJR , (2012) FROM FORM TO FUNCTION: THE ROLE OF NOX4 IN THE CARDIOVASCULAR SYSTEM.FRONTIERS IN PHYSIOLOGY. VOL. 3. ISSUE . P. - 121 82% 35
8 BRANDES, RP , WEISSMANN, N , SCHRODER, K , (2010) NADPH OXIDASES IN CARDIOVASCULAR DISEASE.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 49. ISSUE 5. P. 687 -706 172 51% 110
9 ALTENHOFER, S , RADERMACHER, KA , KLEIKERS, PWM , WINGLER, K , SCHMIDT, HHHW , (2015) EVOLUTION OF NADPH OXIDASE INHIBITORS: SELECTIVITY AND MECHANISMS FOR TARGET ENGAGEMENT.ANTIOXIDANTS & REDOX SIGNALING. VOL. 23. ISSUE 5. P. 406 -427 104 58% 37
10 LASSEGUE, B , CLEMPUS, RE , (2003) VASCULAR NAD(P)H OXIDASES: SPECIFIC FEATURES, EXPRESSION, AND REGULATION.AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. VOL. 285. ISSUE 2. P. R277-R297 123 57% 603

Classes with closest relation at Level 1


Rank Class id link
1 26023 3 4 DIHYDROXY L PHENYL ALANINE//4 HYDROXYNNONENAL//5 HT2B SEROTONIN RECEPTOR AGONIST
2 20881 ENDOTHELIUM DEPENDENT CONTRACTION//ENDOTHELIUM DERIVED CONTRACTING FACTOR//THROMBOXANE PROSTANOID RECEPTOR
3 35392 RED FISIOPATOL ENFERMEDADES HEPAT//ANTI APOPTOTIC SIGNALLING//BIOQUIM BIOL MOL MIXTO
4 31376 ROMO1//MAP17//FREE RAD REGULAT
5 20328 REYNOLDS OKLAHOMA AGING//VASCULAR AGING//DONALD W REYNOLDS GERIATR MED
6 1210 CYTOCHROME B558//NADPH OXIDASE//P47PHOX
7 14232 THYROID DYSGENESIS//THYROID HEMIAGENESIS//BENIGN HEREDITARY CHOREA
8 18943 EXTRACELLULAR SUPEROXIDE DISMUTASE//EC SOD//EXTRACELLULAR SUPEROXIDE DISMUTASE EC SOD
9 16892 GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II
10 29432 ANTITUMOR IMMUN//ABT VIROL//NN BLOKCHIN CANC

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