Class information for:
Level 2: ADAPTIVE DESIGN//STATISTICS IN MEDICINE//STATISTICS & PROBABILITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1075 9928 22.7 55%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
9 4 COMPUTER SCIENCE, THEORY & METHODS//COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE//COMPUTER SCIENCE, INFORMATION SYSTEMS 1247339
34 3       STATISTICS & PROBABILITY//STAT//COMMUNICATIONS IN STATISTICS-THEORY AND METHODS 105938
1075 2             ADAPTIVE DESIGN//STATISTICS IN MEDICINE//STATISTICS & PROBABILITY 9928
1949 1                   ADAPTIVE DESIGN//INTERIM ANALYSIS//GROUP SEQUENTIAL TEST 2411
5338 1                   FALSE DISCOVERY RATE//MULTIPLE TESTING//FAMILYWISE ERROR RATE 1638
9848 1                   UNCONDITIONAL TEST//2 X 2 TABLES//FISHERS EXACT TEST 1115
11983 1                   CLUSTER RANDOMIZED TRIAL//CLUSTER RANDOMIZATION//GROUP RANDOMIZED TRIAL 939
13520 1                   BIOEQUIVALENCE//INDIVIDUAL BIOEQUIVALENCE//HIGHLY VARIABLE DRUGS 831
15440 1                   RESPONSE ADAPTIVE DESIGN//URN MODEL//BIASED COIN DESIGN 713
16116 1                   SUBGROUP ANALYSIS//MULTIREGIONAL CLINICAL TRIAL//MULTIREGIONAL TRIAL 672
21983 1                   ESTIMATION AFTER SELECTION//PROBABILITY OF CORRECT SELECTION//SUBSET SELECTION 398
22251 1                   NONINFERIORITY MARGIN//NON INFERIORITY//THREE ARM DESIGN 389
27428 1                   COVARIATE ADJUSTMENT//LINEAR MODELS EQUATING COVARIATE MEANS//RANDOMIZATION BASED NONPARAMETRIC COVARIANCE ADJUSTMENT 230
29602 1                   PLUG IN POWER ESTIMATION//EXACT P VALUES//28 DAY REPEATED TOXICITY STUDY 183
30357 1                   COMPOSITE ENDPOINTS//WIN RATIO//WORST RANK SCORES 170
31893 1                   CORONARY ANGIOGRAPHY AND INTERVENTION//DOSE ADVERSE EVENT RELATIONSHIP//DOSE LIMITING ADVERSE EFFECTS 146
35726 1                   DESIGN TRIALS STAT GRP//332 N LAUDERDALE POB 318//ADAPTATION AND SELF CARE IN ADOLESCENTS WITH CANCER 93

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ADAPTIVE DESIGN authKW 696505 3% 66% 342
2 STATISTICS IN MEDICINE journal 680488 13% 18% 1259
3 STATISTICS & PROBABILITY WoSSC 565614 58% 3% 5744
4 JOURNAL OF BIOPHARMACEUTICAL STATISTICS journal 445138 4% 40% 364
5 MULTIPLE TESTING authKW 432187 3% 52% 271
6 FALSE DISCOVERY RATE authKW 400000 3% 47% 280
7 FAMILYWISE ERROR RATE authKW 397604 2% 74% 174
8 INTERIM ANALYSIS authKW 363064 2% 78% 151
9 SAMPLE SIZE authKW 330173 5% 24% 452
10 PHARMACEUTICAL STATISTICS journal 314866 2% 44% 232

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Statistics & Probability 565614 58% 3% 5744
2 Mathematical & Computational Biology 228223 28% 3% 2767
3 Medical Informatics 154173 15% 3% 1533
4 Medicine, Research & Experimental 19413 17% 0% 1715
5 Public, Environmental & Occupational Health 14103 16% 0% 1627
6 Pharmacology & Pharmacy 7233 18% 0% 1767
7 Health Care Sciences & Services 6118 6% 0% 567
8 Biology 3485 6% 0% 591
9 Psychology, Mathematical 3106 1% 1% 133
10 Computer Science, Interdisciplinary Applications 962 3% 0% 328

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 BIOMETR 1 116076 0% 79% 48
2 MED PHARMACEUT STAT UNIT 84186 1% 46% 59
3 STAT 56424 11% 2% 1112
4 OFF BIOSTAT 54815 1% 14% 132
5 BIOSTAT 40902 11% 1% 1084
6 MED BIOMETRY UNIT 31612 0% 86% 12
7 OTS CDER 30737 0% 100% 10
8 BIOMETR 4 28818 0% 45% 21
9 BIOSTAT PROGRAMMING 24409 0% 31% 26
10 CDER 23873 1% 14% 54

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 STATISTICS IN MEDICINE 680488 13% 18% 1259
2 JOURNAL OF BIOPHARMACEUTICAL STATISTICS 445138 4% 40% 364
3 PHARMACEUTICAL STATISTICS 314866 2% 44% 232
4 BIOMETRICAL JOURNAL 194927 4% 16% 388
5 CONTROLLED CLINICAL TRIALS 180645 2% 25% 239
6 STATISTICS IN BIOPHARMACEUTICAL RESEARCH 167556 1% 42% 129
7 BIOMETRICS 109204 4% 9% 401
8 CLINICAL TRIALS 105797 2% 22% 160
9 DRUG INFORMATION JOURNAL 84539 2% 16% 174
10 STATISTICAL METHODS IN MEDICAL RESEARCH 52126 1% 15% 112

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADAPTIVE DESIGN 696505 3% 66% 342 Search ADAPTIVE+DESIGN Search ADAPTIVE+DESIGN
2 MULTIPLE TESTING 432187 3% 52% 271 Search MULTIPLE+TESTING Search MULTIPLE+TESTING
3 FALSE DISCOVERY RATE 400000 3% 47% 280 Search FALSE+DISCOVERY+RATE Search FALSE+DISCOVERY+RATE
4 FAMILYWISE ERROR RATE 397604 2% 74% 174 Search FAMILYWISE+ERROR+RATE Search FAMILYWISE+ERROR+RATE
5 INTERIM ANALYSIS 363064 2% 78% 151 Search INTERIM+ANALYSIS Search INTERIM+ANALYSIS
6 SAMPLE SIZE 330173 5% 24% 452 Search SAMPLE+SIZE Search SAMPLE+SIZE
7 MULTIPLE COMPARISONS 264966 2% 43% 199 Search MULTIPLE+COMPARISONS Search MULTIPLE+COMPARISONS
8 GROUP SEQUENTIAL DESIGN 264856 1% 96% 90 Search GROUP+SEQUENTIAL+DESIGN Search GROUP+SEQUENTIAL+DESIGN
9 SAMPLE SIZE RE ESTIMATION 264473 1% 98% 88 Search SAMPLE+SIZE+RE+ESTIMATION Search SAMPLE+SIZE+RE+ESTIMATION
10 CONDITIONAL POWER 254038 1% 92% 90 Search CONDITIONAL+POWER Search CONDITIONAL+POWER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BAUER, P , BRETZ, F , DRAGALIN, V , KONIG, F , WASSMER, G , (2016) TWENTY-FIVE YEARS OF CONFIRMATORY ADAPTIVE DESIGNS: OPPORTUNITIES AND PITFALLS.STATISTICS IN MEDICINE. VOL. 35. ISSUE 3. P. 325 -347 124 94% 7
2 ANTONIOU, M , JORGENSEN, AL , KOLAMUNNAGE-DONA, R , (2016) BIOMARKER-GUIDED ADAPTIVE TRIAL DESIGNS IN PHASE II AND PHASE III: A METHODOLOGICAL REVIEW.PLOS ONE. VOL. 11. ISSUE 2. P. - 99 86% 2
3 RUTTERFORD, C , COPAS, A , ELDRIDGE, S , (2015) METHODS FOR SAMPLE SIZE DETERMINATION IN CLUSTER RANDOMIZED TRIALS.INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. VOL. 44. ISSUE 3. P. 1051 -1067 81 84% 2
4 ONDRA, T , DMITRIENKO, A , FRIEDE, T , GRAF, A , MILLER, F , STALLARD, N , POSCH, M , (2016) METHODS FOR IDENTIFICATION AND CONFIRMATION OF TARGETED SUBGROUPS IN CLINICAL TRIALS: A SYSTEMATIC REVIEW.JOURNAL OF BIOPHARMACEUTICAL STATISTICS. VOL. 26. ISSUE 1. P. 99 -119 65 90% 2
5 VANDEMEULEBROECKE, M , (2008) GROUP SEQUENTIAL AND ADAPTIVE DESIGNS - A REVIEW OF BASIC CONCEPTS AND POINTS OF DISCUSSION.BIOMETRICAL JOURNAL. VOL. 50. ISSUE 4. P. 541 -557 76 100% 12
6 ROSENBERGER, WF , SVERDLOV, O , HU, FF , (2012) ADAPTIVE RANDOMIZATION FOR CLINICAL TRIALS.JOURNAL OF BIOPHARMACEUTICAL STATISTICS. VOL. 22. ISSUE 4. P. 719 -736 69 96% 10
7 TANNIOU, J , VAN DER TWEEL, I , TEERENSTRA, S , ROES, KCB , (2016) SUBGROUP ANALYSES IN CONFIRMATORY CLINICAL TRIALS: TIME TO BE SPECIFIC ABOUT THEIR PURPOSES.BMC MEDICAL RESEARCH METHODOLOGY. VOL. 16. ISSUE . P. - 65 97% 0
8 GOEMAN, JJ , SOLARI, A , (2014) MULTIPLE HYPOTHESIS TESTING IN GENOMICS.STATISTICS IN MEDICINE. VOL. 33. ISSUE 11. P. 1946-1978 59 81% 22
9 BRETZ, F , KOENIG, F , BRANNATH, W , GLIMM, E , POSCH, M , (2009) ADAPTIVE DESIGNS FOR CONFIRMATORY CLINICAL TRIALS.STATISTICS IN MEDICINE. VOL. 28. ISSUE 8. P. 1181 -1217 54 96% 60
10 ALOSH, M , BRETZ, F , HUQUE, M , (2014) ADVANCED MULTIPLICITY ADJUSTMENT METHODS IN CLINICAL TRIALS.STATISTICS IN MEDICINE. VOL. 33. ISSUE 4. P. 693-713 50 100% 7

Classes with closest relation at Level 2


Rank Class id link
1 2331 STATISTICS & PROBABILITY//ORDER RESTRICTED INFERENCE//ORDERED ALTERNATIVES
2 3420 CONTINUAL REASSESSMENT METHOD//DOSE FINDING//PHASE I TRIAL
3 3097 EFFECT SIZE//NULL HYPOTHESIS SIGNIFICANCE TESTING//NHST
4 319 STATISTICS & PROBABILITY//STATISTICS IN MEDICINE//BIOMETRICS
5 3220 AMERICAN STATISTICIAN//STATISTICAL EDUCATION//STATISTICS EDUCATION
6 1009 EVIDENCE BASED MEDICINE//PUBLICATION BIAS//RESEARCH SYNTHESIS METHODS
7 2582 ROC CURVE//VERIFICATION BIAS//DIAGNOSTIC TESTS
8 970 STATISTICS & PROBABILITY//COMMUNICATIONS IN STATISTICS-THEORY AND METHODS//LOCAL INFLUENCE
9 1916 DIRICHLET PROCESS//BAYESIAN NONPARAMETRICS//STATISTICS & PROBABILITY
10 1716 D OPTIMALITY//STATISTICS & PROBABILITY//JOURNAL OF STATISTICAL PLANNING AND INFERENCE

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