Class information for:
Level 1: ADAPTIVE DESIGN//INTERIM ANALYSIS//GROUP SEQUENTIAL TEST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1949 2411 22.9 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
9 4 COMPUTER SCIENCE, THEORY & METHODS//COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE//COMPUTER SCIENCE, INFORMATION SYSTEMS 1247339
34 3       STATISTICS & PROBABILITY//STAT//COMMUNICATIONS IN STATISTICS-THEORY AND METHODS 105938
1075 2             ADAPTIVE DESIGN//STATISTICS IN MEDICINE//STATISTICS & PROBABILITY 9928
1949 1                   ADAPTIVE DESIGN//INTERIM ANALYSIS//GROUP SEQUENTIAL TEST 2411

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADAPTIVE DESIGN authKW 1533562 10% 48% 250
2 INTERIM ANALYSIS authKW 1285928 6% 73% 140
3 GROUP SEQUENTIAL TEST authKW 918953 3% 92% 79
4 CONDITIONAL POWER authKW 911727 3% 86% 84
5 SAMPLE SIZE RE ESTIMATION authKW 900477 3% 89% 80
6 GROUP SEQUENTIAL DESIGN authKW 840731 3% 84% 79
7 INTERIM ANALYSES authKW 515285 2% 88% 46
8 STATISTICS IN MEDICINE journal 399385 20% 7% 475
9 TWO STAGE DESIGN authKW 388387 3% 46% 66
10 DATA MONITORING COMMITTEE authKW 370379 2% 75% 39

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Statistics & Probability 154171 61% 1% 1477
2 Mathematical & Computational Biology 96472 37% 1% 884
3 Medical Informatics 85890 23% 1% 562
4 Medicine, Research & Experimental 12683 27% 0% 663
5 Public, Environmental & Occupational Health 7005 23% 0% 549
6 Pharmacology & Pharmacy 3446 24% 0% 572
7 Biology 2399 9% 0% 229
8 Health Care Sciences & Services 1892 6% 0% 154
9 Oncology 181 7% 0% 161
10 Computer Science, Interdisciplinary Applications 50 2% 0% 46

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MED PHARMACEUT STAT UNIT 269555 2% 41% 52
2 MED BIOMETRY UNIT 109442 0% 79% 11
3 BIOMETR 1 91521 1% 34% 21
4 OB CDER 37990 0% 100% 3
5 COMPETENCE CLIN TRIALS 35171 0% 56% 5
6 BIOMETRY MATH STAT BRANCH 32904 1% 20% 13
7 STAT DRUG DEV 32556 0% 43% 6
8 OTS CDER 31653 0% 50% 5
9 BIOMETR ADV ANALYT 25326 0% 100% 2
10 BIOTX STAT 25326 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STATISTICS IN MEDICINE 399385 20% 7% 475
2 JOURNAL OF BIOPHARMACEUTICAL STATISTICS 279127 6% 16% 142
3 PHARMACEUTICAL STATISTICS 222137 4% 18% 96
4 CONTROLLED CLINICAL TRIALS 213669 5% 13% 128
5 CLINICAL TRIALS 114608 3% 11% 82
6 STATISTICS IN BIOPHARMACEUTICAL RESEARCH 80305 2% 14% 44
7 BIOMETRICS 79171 7% 4% 168
8 BIOMETRICAL JOURNAL 46112 4% 4% 93
9 DRUG INFORMATION JOURNAL 45697 3% 6% 63
10 CONTEMPORARY CLINICAL TRIALS 31351 2% 4% 59

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADAPTIVE DESIGN 1533562 10% 48% 250 Search ADAPTIVE+DESIGN Search ADAPTIVE+DESIGN
2 INTERIM ANALYSIS 1285928 6% 73% 140 Search INTERIM+ANALYSIS Search INTERIM+ANALYSIS
3 GROUP SEQUENTIAL TEST 918953 3% 92% 79 Search GROUP+SEQUENTIAL+TEST Search GROUP+SEQUENTIAL+TEST
4 CONDITIONAL POWER 911727 3% 86% 84 Search CONDITIONAL+POWER Search CONDITIONAL+POWER
5 SAMPLE SIZE RE ESTIMATION 900477 3% 89% 80 Search SAMPLE+SIZE+RE+ESTIMATION Search SAMPLE+SIZE+RE+ESTIMATION
6 GROUP SEQUENTIAL DESIGN 840731 3% 84% 79 Search GROUP+SEQUENTIAL+DESIGN Search GROUP+SEQUENTIAL+DESIGN
7 INTERIM ANALYSES 515285 2% 88% 46 Search INTERIM+ANALYSES Search INTERIM+ANALYSES
8 TWO STAGE DESIGN 388387 3% 46% 66 Search TWO+STAGE+DESIGN Search TWO+STAGE+DESIGN
9 DATA MONITORING COMMITTEE 370379 2% 75% 39 Search DATA+MONITORING+COMMITTEE Search DATA+MONITORING+COMMITTEE
10 GROUP SEQUENTIAL 323157 1% 73% 35 Search GROUP+SEQUENTIAL Search GROUP+SEQUENTIAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BAUER, P , BRETZ, F , DRAGALIN, V , KONIG, F , WASSMER, G , (2016) TWENTY-FIVE YEARS OF CONFIRMATORY ADAPTIVE DESIGNS: OPPORTUNITIES AND PITFALLS.STATISTICS IN MEDICINE. VOL. 35. ISSUE 3. P. 325 -347 114 86% 7
2 VANDEMEULEBROECKE, M , (2008) GROUP SEQUENTIAL AND ADAPTIVE DESIGNS - A REVIEW OF BASIC CONCEPTS AND POINTS OF DISCUSSION.BIOMETRICAL JOURNAL. VOL. 50. ISSUE 4. P. 541 -557 76 100% 12
3 TODD, S , (2007) A 25-YEAR REVIEW OF SEQUENTIAL METHODOLOGY IN CLINICAL STUDIES.STATISTICS IN MEDICINE. VOL. 26. ISSUE 2. P. 237-252 70 83% 19
4 BRETZ, F , KOENIG, F , BRANNATH, W , GLIMM, E , POSCH, M , (2009) ADAPTIVE DESIGNS FOR CONFIRMATORY CLINICAL TRIALS.STATISTICS IN MEDICINE. VOL. 28. ISSUE 8. P. 1181 -1217 51 91% 60
5 PRITCHETT, YL , MENON, S , MARCHENKO, O , ANTONIJEVIC, Z , MILLER, E , SANCHEZ-KAM, M , MORGAN-BOUNIOL, CC , NGUYEN, H , PRUCKA, WR , (2015) SAMPLE SIZE RE-ESTIMATION DESIGNS IN CONFIRMATORY CLINICAL TRIALS-CURRENT STATE, STATISTICAL CONSIDERATIONS, AND PRACTICAL GUIDANCE.STATISTICS IN BIOPHARMACEUTICAL RESEARCH. VOL. 7. ISSUE 4. P. 309 -321 47 96% 0
6 GRANT, AM , ALTMAN, DG , BABIKER, AB , CAMPBELL, MK , CLEMENS, FJ , DARBYSHIRE, JH , ELBOURNE, DR , MCLEER, SK , PARMAR, MKB , POCOCK, SJ , ET AL (2005) ISSUES IN DATA MONITORING AND INTERIM ANALYSIS OF TRIALS.HEALTH TECHNOLOGY ASSESSMENT. VOL. 9. ISSUE 7. P. 1-+ 88 58% 54
7 HAMPSON, LV , JENNISON, C , (2013) GROUP SEQUENTIAL TESTS FOR DELAYED RESPONSES.JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY. VOL. 75. ISSUE 1. P. 3 -39 39 93% 10
8 DRAGALIN, V , (2006) ADAPTIVE DESIGNS: TERMINOLOGY AND CLASSIFICATION.DRUG INFORMATION JOURNAL. VOL. 40. ISSUE 4. P. 425-435 53 77% 62
9 JENNISON, C , TURNBULL, BW , (2007) ADAPTIVE SEAMLESS DESIGNS: SELECTION AND PROSPECTIVE TESTING OF HYPOTHESES.JOURNAL OF BIOPHARMACEUTICAL STATISTICS. VOL. 17. ISSUE 6. P. 1135-1161 48 86% 24
10 WASSMER, G , (2000) BASIC CONCEPTS OF GROUP SEQUENTIAL AND ADAPTIVE GROUP SEQUENTIAL TEST PROCEDURES.STATISTICAL PAPERS. VOL. 41. ISSUE 3. P. 253 -279 52 100% 17

Classes with closest relation at Level 1


Rank Class id link
1 16116 SUBGROUP ANALYSIS//MULTIREGIONAL CLINICAL TRIAL//MULTIREGIONAL TRIAL
2 35726 DESIGN TRIALS STAT GRP//332 N LAUDERDALE POB 318//ADAPTATION AND SELF CARE IN ADOLESCENTS WITH CANCER
3 15440 RESPONSE ADAPTIVE DESIGN//URN MODEL//BIASED COIN DESIGN
4 22251 NONINFERIORITY MARGIN//NON INFERIORITY//THREE ARM DESIGN
5 13262 CONTINUAL REASSESSMENT METHOD//DOSE FINDING//PHASE I TRIAL
6 5338 FALSE DISCOVERY RATE//MULTIPLE TESTING//FAMILYWISE ERROR RATE
7 30020 BENEFIT RISK//BENEFIT RISK ASSESSMENT//BENEFIT RISK COMMUNICATION
8 18139 SURROGATE ENDPOINT//SURROGATE OUTCOME//PRENTICE CRITERION
9 29602 PLUG IN POWER ESTIMATION//EXACT P VALUES//28 DAY REPEATED TOXICITY STUDY
10 9848 UNCONDITIONAL TEST//2 X 2 TABLES//FISHERS EXACT TEST

Go to start page