Class information for:
Level 1: P21//P21WAF1 CIP1//P21WAF1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9064 1190 43.5 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
483 2             CYCLIN DEPENDENT KINASE//CELL CYCLE//CDK5 15640
9064 1                   P21//P21WAF1 CIP1//P21WAF1 1190

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P21 authKW 691415 19% 12% 228
2 P21WAF1 CIP1 authKW 542446 8% 23% 93
3 P21WAF1 authKW 259813 6% 15% 66
4 WAF1 authKW 234561 2% 38% 24
5 WAF1 CIP1 authKW 149281 1% 73% 8
6 CIP1 authKW 140789 1% 37% 15
7 P21 GENE authKW 125722 1% 70% 7
8 SEZ PATOL GEN C GOLGI address 104766 1% 58% 7
9 P21CIP1 WAF1 authKW 93532 2% 19% 19
10 SDI1 authKW 80179 0% 63% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7175 41% 0% 483
2 Cell Biology 4263 31% 0% 373
3 Biochemistry & Molecular Biology 1903 35% 0% 419
4 Genetics & Heredity 984 13% 0% 156
5 Pathology 464 6% 0% 74
6 Biophysics 147 5% 0% 61
7 Medicine, Research & Experimental 77 4% 0% 50
8 Gastroenterology & Hepatology 30 2% 0% 28
9 Toxicology 16 2% 0% 23
10 Developmental Biology 15 1% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SEZ PATOL GEN C GOLGI 104766 1% 58% 7
2 ZHANGHAI HOSP 51317 0% 100% 2
3 BIOL CELLULAIRE MOL CONTROLE PROLIFERAT CEL 34210 0% 67% 2
4 MINIST EDUC BREAST CANC PREVENT TREATME 34210 0% 67% 2
5 NEW PROD 4 32986 0% 43% 3
6 BIOL MOL BIOMED BIOTECNOL CANTABRIA I 25658 0% 100% 1
7 CANC HOSP REPROD HERED 25658 0% 100% 1
8 CANC MOL BIOL GRP 25658 0% 100% 1
9 CELL CYCLE GEN STABIL 25658 0% 100% 1
10 CELL MOL BIOL GENE THER Y PROJECT 25658 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR AND CELLULAR DIFFERENTIATION 57139 1% 32% 7
2 ONCOGENE 14439 8% 1% 101
3 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 2262 2% 0% 21
4 UROLOGIC ONCOLOGY 2093 0% 3% 3
5 INTERNATIONAL JOURNAL OF ONCOLOGY 1923 2% 0% 27
6 CANCER RESEARCH 1325 4% 0% 46
7 MOLECULAR CARCINOGENESIS 1313 1% 0% 12
8 CELL GROWTH & DIFFERENTIATION 1152 1% 1% 8
9 MOLECULAR AND CELLULAR BIOLOGY 859 2% 0% 28
10 CLINICAL CANCER RESEARCH 728 2% 0% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 P21 691415 19% 12% 228 Search P21 Search P21
2 P21WAF1 CIP1 542446 8% 23% 93 Search P21WAF1+CIP1 Search P21WAF1+CIP1
3 P21WAF1 259813 6% 15% 66 Search P21WAF1 Search P21WAF1
4 WAF1 234561 2% 38% 24 Search WAF1 Search WAF1
5 WAF1 CIP1 149281 1% 73% 8 Search WAF1+CIP1 Search WAF1+CIP1
6 CIP1 140789 1% 37% 15 Search CIP1 Search CIP1
7 P21 GENE 125722 1% 70% 7 Search P21+GENE Search P21+GENE
8 P21CIP1 WAF1 93532 2% 19% 19 Search P21CIP1+WAF1 Search P21CIP1+WAF1
9 SDI1 80179 0% 63% 5 Search SDI1 Search SDI1
10 P21 WAF1 CIP1 SDI1 68420 0% 67% 4 Search P21+WAF1+CIP1+SDI1 Search P21+WAF1+CIP1+SDI1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CAZZALINI, O , SCOVASSI, AI , SAVIO, M , STIVALA, LA , PROSPERI, E , (2010) MULTIPLE ROLES OF THE CELL CYCLE INHIBITOR P21(CDKN1A) IN THE DNA DAMAGE RESPONSE.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 704. ISSUE 1-3. P. 12-20 96 64% 133
2 ABBAS, T , DUTTA, A , (2009) P21 IN CANCER: INTRICATE NETWORKS AND MULTIPLE ACTIVITIES.NATURE REVIEWS CANCER. VOL. 9. ISSUE 6. P. 400 -414 87 39% 794
3 GARTEL, AL , TYNER, AL , (2002) THE ROLE OF THE CYCLIN-DEPENDENT KINASE INHIBITOR P21 IN APOPTOSIS.MOLECULAR CANCER THERAPEUTICS. VOL. 1. ISSUE 8. P. 639-649 91 54% 620
4 KREIS, NN , LOUWEN, F , YUAN, J , (2015) LESS UNDERSTOOD ISSUES: P21(CIP1) IN MITOSIS AND ITS THERAPEUTIC POTENTIAL.ONCOGENE. VOL. 34. ISSUE 14. P. 1758 -1767 84 50% 15
5 STIVALA, LA , CAZZALINI, O , PROSPERI, E , (2012) THE CYCLIN-DEPENDENT KINASE INHIBITOR P21(CDKN1A) AS A TARGET OF ANTI-CANCER DRUGS.CURRENT CANCER DRUG TARGETS. VOL. 12. ISSUE 2. P. 85 -96 77 54% 29
6 DUTTO, I , TILLHON, M , CAZZALINI, O , STIVALA, LA , PROSPERI, E , (2015) BIOLOGY OF THE CELL CYCLE INHIBITOR P21(CDKN1A): MOLECULAR MECHANISMS AND RELEVANCE IN CHEMICAL TOXICOLOGY.ARCHIVES OF TOXICOLOGY. VOL. 89. ISSUE 2. P. 155 -178 97 31% 17
7 ROMANOV, VS , POSPELOV, VA , POSPELOVA, TV , (2012) CYCLIN-DEPENDENT KINASE INHIBITOR P21(WAF1): CONTEMPORARY VIEW ON ITS ROLE IN SENESCENCE AND ONCOGENESIS.BIOCHEMISTRY-MOSCOW. VOL. 77. ISSUE 6. P. 575 -584 63 53% 59
8 WAGNER, M , KLUSSMANN, JP , FANGMANN, R , LINDER, R , ELEWA, ME , EIDT, S , ROSE, VMA , JUNGEHULSING, M , SCHULZE, HJ , (2001) CYCLIN-DEPENDENT KINASE-INHIBITOR 1 (CDKN1A) IN THE SQUAMOUS EPITHELIUM OF THE OROPHARYNX: POSSIBLE IMPLICATIONS OF MOLECULAR BIOLOGY AND COMPARTMENTATION.ANTICANCER RESEARCH. VOL. 21. ISSUE 1A. P. 333-345 100 54% 5
9 WEINBERG, WC , DENNING, MF , (2002) P21(WAF1) CONTROL OF EPITHELIAL CELL CYCLE AND CELL FATE.CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE. VOL. 13. ISSUE 6. P. 453-464 77 57% 104
10 RONINSON, IB , (2002) ONCOGENIC FUNCTIONS OF TUMOUR SUPPRESSOR P21 (WAF1/CIP1/SDI1): ASSOCIATION WITH CELL SENESCENCE AND TUMOUR-PROMOTING ACTIVITIES OF STROMAL FIBROBLASTS.CANCER LETTERS. VOL. 179. ISSUE 1. P. 1-14 63 48% 251

Classes with closest relation at Level 1


Rank Class id link
1 5545 SKP2//P27KIP1//P27
2 1581 P53//P53 GENE//ONCOGENE
3 5472 CYCLIN D1//CCND1//CYCLIN D3
4 19975 GADD45//GADD45A//GADD45 ALPHA
5 23606 CAK//SPY1//CDK ACTIVATING KINASE
6 16830 RAD P53//RECOMBINANT ADENOVIRUS P53//ADENOVIRAL MEDIATED INTERFERON ALPHA
7 4549 P16//CDKN2A//P16INK4A
8 9053 P53 POLYMORPHISM//P53 CODON 72//CODON 72
9 37546 KIAA0101//NS5ATP9//OEATC 1
10 11121 TUMOR FRONT GRADING//ORAL SQUAMOUS CELL CARCINOMA//P53

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