Class information for:
Level 1: CAK//SPY1//CDK ACTIVATING KINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23606 340 46.1 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
483 2             CYCLIN DEPENDENT KINASE//CELL CYCLE//CDK5 15640
23606 1                   CAK//SPY1//CDK ACTIVATING KINASE 340

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CAK authKW 1357387 7% 66% 23
2 SPY1 authKW 574776 2% 80% 8
3 CDK ACTIVATING KINASE authKW 571934 3% 58% 11
4 CYCLIN H authKW 427906 3% 53% 9
5 CDKN3 authKW 374204 1% 83% 5
6 SPEEDY authKW 374204 1% 83% 5
7 CDK7 authKW 315411 4% 29% 12
8 RINGO authKW 280650 1% 63% 5
9 CELL CYCLE G1 EXIT authKW 269428 1% 100% 3
10 LM23 authKW 269428 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 2745 46% 0% 156
2 Biochemistry & Molecular Biology 1714 58% 0% 198
3 Oncology 202 14% 0% 49
4 Biophysics 136 8% 0% 28
5 Genetics & Heredity 102 9% 0% 29
6 Medicine, Research & Experimental 62 6% 0% 21
7 Andrology 25 1% 0% 2
8 Biochemical Research Methods 25 4% 0% 13
9 Cell & Tissue Engineering 10 1% 0% 2
10 Developmental Biology 10 1% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EARNEST ORLANDO BERKELEY 179619 1% 100% 2
2 ANGELES SABAN 89809 0% 100% 1
3 BIOMOL MAX MOUSSERON IBMM CNRS UMR 5247 89809 0% 100% 1
4 CRBM ERS155 89809 0% 100% 1
5 CRBM INSERM U249 89809 0% 100% 1
6 DANA FARBER BRIGHAM 89809 0% 100% 1
7 GENET TERATOL BD 89809 0% 100% 1
8 GENT MOL PLANTES 89809 0% 100% 1
9 IMMUNOLBMT 89809 0% 100% 1
10 IUOPAAREA FISIOL 89809 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 M S-MEDECINE SCIENCES 6889 5% 0% 16
2 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 3555 4% 0% 14
3 EMBO JOURNAL 2297 6% 0% 21
4 MOLECULAR AND CELLULAR BIOLOGY 1146 5% 0% 17
5 JOURNAL OF BIOLOGICAL CHEMISTRY 729 11% 0% 36
6 CURRENT OPINION IN CELL BIOLOGY 539 1% 0% 4
7 NATURE STRUCTURAL BIOLOGY 508 1% 0% 3
8 IRANIAN JOURNAL OF BIOTECHNOLOGY 449 0% 1% 1
9 CURRENT OPINION IN GENETICS & DEVELOPMENT 408 1% 0% 3
10 MOLECULAR BIOLOGY OF THE CELL 379 2% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CAK 1357387 7% 66% 23 Search CAK Search CAK
2 SPY1 574776 2% 80% 8 Search SPY1 Search SPY1
3 CDK ACTIVATING KINASE 571934 3% 58% 11 Search CDK+ACTIVATING+KINASE Search CDK+ACTIVATING+KINASE
4 CYCLIN H 427906 3% 53% 9 Search CYCLIN+H Search CYCLIN+H
5 CDKN3 374204 1% 83% 5 Search CDKN3 Search CDKN3
6 SPEEDY 374204 1% 83% 5 Search SPEEDY Search SPEEDY
7 CDK7 315411 4% 29% 12 Search CDK7 Search CDK7
8 RINGO 280650 1% 63% 5 Search RINGO Search RINGO
9 CELL CYCLE G1 EXIT 269428 1% 100% 3 Search CELL+CYCLE+G1+EXIT Search CELL+CYCLE+G1+EXIT
10 LM23 269428 1% 100% 3 Search LM23 Search LM23

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FISHER, RP , (2005) SECRETS OF A DOUBLE AGENT: CDK7 IN CELL-CYCLE CONTROL AND TRANSCRIPTION.JOURNAL OF CELL SCIENCE. VOL. 118. ISSUE 22. P. 5171-5180 55 48% 132
2 KALDIS, P , SOLOMON, MJ , (2000) ANALYSIS OF CAK ACTIVITIES FROM HUMAN CELLS.EUROPEAN JOURNAL OF BIOCHEMISTRY. VOL. 267. ISSUE 13. P. 4213 -4221 44 65% 38
3 WOHLBOLD, L , LAROCHELLE, S , LIAO, JCF , LIVSHITS, G , SINGER, J , SHOKAT, KM , FISHER, RP , (2006) THE CYCLIN-DEPENDENT KINASE (CDK) FAMILY MEMBER PNQALRE/CCRK SUPPORTS CELL PROLIFERATION BUT HAS NO INTRINSIC CDK-ACTIVATING KINASE (CAK) ACTIVITY.CELL CYCLE. VOL. 5. ISSUE 5. P. 546 -554 34 69% 29
4 CHAO, WS , SERPE, MD , JIA, Y , SHELVER, WLL , ANDERSON, JV , UMEDA, M , (2007) POTENTIAL ROLES FOR AUTOPHOSPHORYLATION, KINASE ACTIVITY, AND ABUNDANCE OF A CDK-ACTIVATING KINASE (EE;CDKF;1) DURING GROWTH IN LEAFY SPURGE.PLANT MOLECULAR BIOLOGY. VOL. 63. ISSUE 3. P. 365 -379 38 62% 2
5 KALDIS, P , (1999) THE CDK-ACTIVATING KINASE (CAK): FROM YEAST TO MAMMALS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 55. ISSUE 2. P. 284-296 57 40% 138
6 TSAKRAKLIDES, V , SOLOMON, MJ , (2002) COMPARISON OF CAK1P-LIKE CYCLIN-DEPENDENT KINASE-ACTIVATING KINASES.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 277. ISSUE 36. P. 33482 -33489 32 71% 26
7 HARPER, JW , ELLEDGE, SJ , (1998) THE ROLE OF CDK7 IN CAK FUNCTION, A RETRO-RETROSPECTIVE.GENES & DEVELOPMENT. VOL. 12. ISSUE 3. P. 285 -289 32 71% 116
8 LAROCHELLE, S , MERRICK, KA , TERRET, ME , WOHLBOLD, L , BARBOZA, NM , ZHANG, C , SHOKAT, KM , JALLEPALLI, PV , FISHER, RP , (2007) REQUIREMENTS FOR CDK7 IN THE ASSEMBLY OF CDK1/CYCLIN B AND ACTIVATION OF CDK2 REVEALED BY CHEMICAL GENETICS IN HUMAN CELLS.MOLECULAR CELL. VOL. 25. ISSUE 6. P. 839 -850 27 63% 84
9 LIU, Y , WU, CW , GALAKTIONOV, K , (2004) P42, A NOVEL CYCLIN-DEPENDENT KINASE-ACTIVATING KINASE IN MAMMALIAN CELLS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 279. ISSUE 6. P. 4507-4514 27 75% 37
10 LOLLI, G , JOHNSON, LN , (2005) CAK-CYCLIN-DEPENDENT ACTIVATING KINASE - A KEY KINASE IN CELL CYCLE CONTROL AND A TARGET FOR DRUGS?.CELL CYCLE. VOL. 4. ISSUE 4. P. 572-577 43 43% 84

Classes with closest relation at Level 1


Rank Class id link
1 7118 FLAVOPIRIDOL//CYCLIN DEPENDENT KINASE//ROSCOVITINE
2 2551 MPF//CDC2//GREATWALL
3 5889 P TEFB//CDK9//RNA POLYMERASE II
4 34552 CCNG2//CYCLIN G2//CYCLIN G
5 36779 CDK11P58//PITSLRE//CDK11
6 8952 ENDOREDUPLICATION//PLANT CELL CYCLE//ENDOPOLYPLOIDY
7 12036 START//MBF//SIC1
8 5545 SKP2//P27KIP1//P27
9 11551 CDK5//P35//CYCLIN DEPENDENT KINASE 5
10 20729 PHO85//P I TRANSPORTER//PHO84

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