Class information for:
Level 1: P16//CDKN2A//P16INK4A

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4549 1767 40.0 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
304 3       P53//RETINOBLASTOMA//MDM2 40663
483 2             CYCLIN DEPENDENT KINASE//CELL CYCLE//CDK5 15640
4549 1                   P16//CDKN2A//P16INK4A 1767

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P16 authKW 769298 15% 16% 273
2 CDKN2A authKW 676486 6% 36% 110
3 P16INK4A authKW 439396 8% 18% 144
4 FAMILIAL MELANOMA authKW 387761 2% 61% 37
5 CDKN2 authKW 338861 2% 63% 31
6 P16 GENE authKW 258094 2% 43% 35
7 P14ARF authKW 222066 3% 21% 60
8 P15 authKW 173645 2% 30% 34
9 MTS1 authKW 173162 1% 48% 21
10 P16INK4 authKW 153090 1% 37% 24

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 20006 55% 0% 967
2 Dermatology 2756 10% 0% 175
3 Genetics & Heredity 2706 17% 0% 305
4 Pathology 1131 8% 0% 137
5 Cell Biology 1130 15% 0% 258
6 Hematology 761 7% 0% 125
7 Biochemistry & Molecular Biology 499 18% 0% 318
8 Medicine, Research & Experimental 351 6% 0% 113
9 Gastroenterology & Hepatology 69 3% 0% 48
10 Biophysics 27 3% 0% 46

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENET RARE HEREDITARY CANC 61428 0% 44% 8
2 JOINT EXPT ONCOL PROGRAM 50807 1% 29% 10
3 MUTAT DETECT IL 40309 0% 33% 7
4 GENET EPIDEMIOL BRANCH 38844 2% 6% 35
5 INTERNAL MED CMOL CELL BIOL 34558 0% 100% 2
6 WESTMEAD CANC 28829 1% 7% 25
7 ABDOMINAL VASC TRANSPLANTAT SURG 2 23038 0% 67% 2
8 MELANOMA GENET PROGRAM 23038 0% 67% 2
9 ONCOL BIOL GENET 19996 1% 6% 20
10 AETIOLCANC HOSP 17279 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MELANOMA RESEARCH 21670 3% 3% 47
2 ONCOGENE 11266 6% 1% 109
3 GENES CHROMOSOMES & CANCER 7821 2% 1% 38
4 CANCER RESEARCH 5428 6% 0% 112
5 INTERNATIONAL JOURNAL OF CANCER 3872 4% 0% 68
6 INTERNATIONAL JOURNAL OF ONCOLOGY 3291 2% 0% 43
7 MOLECULAR CARCINOGENESIS 2715 1% 1% 21
8 LEUKEMIA 2150 2% 0% 31
9 JAPANESE JOURNAL OF CANCER RESEARCH 1728 1% 1% 19
10 JOURNAL OF INVESTIGATIVE DERMATOLOGY 1525 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 P16 769298 15% 16% 273 Search P16 Search P16
2 CDKN2A 676486 6% 36% 110 Search CDKN2A Search CDKN2A
3 P16INK4A 439396 8% 18% 144 Search P16INK4A Search P16INK4A
4 FAMILIAL MELANOMA 387761 2% 61% 37 Search FAMILIAL+MELANOMA Search FAMILIAL+MELANOMA
5 CDKN2 338861 2% 63% 31 Search CDKN2 Search CDKN2
6 P16 GENE 258094 2% 43% 35 Search P16+GENE Search P16+GENE
7 P14ARF 222066 3% 21% 60 Search P14ARF Search P14ARF
8 P15 173645 2% 30% 34 Search P15 Search P15
9 MTS1 173162 1% 48% 21 Search MTS1 Search MTS1
10 P16INK4 153090 1% 37% 24 Search P16INK4 Search P16INK4

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RUAS, M , PETERS, G , (1998) THE P16(INK4A)/CDKN2A TUMOR SUPPRESSOR AND ITS RELATIVES.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1378. ISSUE 2. P. F115 -F177 344 65% 528
2 ROCCO, JW , SIDRANSKY, D , (2001) P16(MTS-1/CDKN2/INK4A) IN CANCER PROGRESSION.EXPERIMENTAL CELL RESEARCH. VOL. 264. ISSUE 1. P. 42 -55 170 69% 297
3 PIEPKORN, M , (2000) MELANOMA GENETICS: AN UPDATE WITH FOCUS ON THE CDKN2A(P16)/ARF TUMOR SUPPRESSORS.JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. VOL. 42. ISSUE 5. P. 705-722 118 73% 86
4 LIGGETT, WH , SIDRANSKY, D , (1998) ROLE OF THE P16 TUMOR SUPPRESSOR GENE IN CANCER.JOURNAL OF CLINICAL ONCOLOGY. VOL. 16. ISSUE 3. P. 1197 -1206 85 70% 377
5 DREXLER, HG , (1998) REVIEW OF ALTERATIONS OF THE CYCLIN-DEPENDENT KINASE INHIBITOR INK4 FAMILY GENES P15, P16, P18 AND P19 IN HUMAN LEUKEMIA-LYMPHOMA CELLS.LEUKEMIA. VOL. 12. ISSUE 6. P. 845 -859 86 72% 298
6 LEACHMAN, SA , CARUCCI, J , KOHLMANN, W , BANKS, KC , ASGARI, MM , BERGMAN, W , BIANCHI-SCARRA, G , BRENTNALL, T , BRESSAC-DE PAILLERETS, B , BRUNO, W , ET AL (2009) SELECTION CRITERIA FOR GENETIC ASSESSMENT OF PATIENTS WITH FAMILIAL MELANOMA.JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. VOL. 61. ISSUE 4. P. 677 -684 63 82% 27
7 FOULKES, WD , FLANDERS, TY , POLLOCK, PM , HAYWARD, NK , (1997) THE CDKN2A (P16) GENE AND HUMAN CANCER.MOLECULAR MEDICINE. VOL. 3. ISSUE 1. P. 5-20 67 83% 118
8 GOLDSTEIN, AM , CHAN, M , HARLAND, M , GILLANDERS, EM , HAYWARD, NK , AVRIL, MF , AZIZI, E , BIANCHI-SCARRA, G , BISHOP, DT , BRESSAC-DE PAILLERETS, B , ET AL (2006) HIGH-RISK MELANOMA SUSCEPTIBILITY GENES AND PANCREATIC CANCER, NEURAL SYSTEM TUMORS, AND UVEAL MELANOMA ACROSS GENOMEL.CANCER RESEARCH. VOL. 66. ISSUE 20. P. 9818-9828 47 85% 122
9 KANNENGIESSER, C , BROOKES, S , DEL ARROYO, AG , PHAM, D , BOMBLED, J , BARROIS, M , MAUFFRET, O , AVRIL, MF , CHOMPRET, A , LENOIR, GM , ET AL (2009) FUNCTIONAL, STRUCTURAL, AND GENETIC EVALUATION OF 20 CDKN2A GERM LINE MUTATIONS IDENTIFIED IN MELANOMA-PRONE FAMILIES OR PATIENTS.HUMAN MUTATION. VOL. 30. ISSUE 4. P. 564-574 50 83% 15
10 GOLDSTEIN, AM , (2004) FAMILIAL MELANOMA, PANCREATIC CANCER AND GERMLINE CDKN2A MUTATIONS.HUMAN MUTATION. VOL. 23. ISSUE 6. P. 630-+ 54 81% 53

Classes with closest relation at Level 1


Rank Class id link
1 23426 CELLULAR HEMOSTASIS//NEVOCELLULAR NEVI//SKIN DIS PROGRAM
2 13568 NUCLEOPHOSMIN//B23//NUCLEOPHOSMIN B23
3 15761 LUNG CANC PROGRAM//HYPERMETHYLATION//MILTON J DANCE HEAD NECK
4 5472 CYCLIN D1//CCND1//CYCLIN D3
5 22214 MTAP//METHYLTHIOADENOSINE PHOSPHORYLASE//METHIONINE SALVAGE PATHWAY
6 27163 MOL DIAGNOST RD//P16INK4A METHYLATION//TRIPLE COMBINATION ARRAY
7 9064 P21//P21WAF1 CIP1//P21WAF1
8 10356 METHYLTRANSFERASE ACTIVITY//DNA METHYLATION//METHYL BINDING DOMAIN PROTEIN
9 1026 MELANOMA//SKIN SELF EXAMINATION//DYSPLASTIC NEVUS
10 16041 P16INK4A//PROEX C//CERVICAL INTRAEPITHELIAL NEOPLASIA

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