Class information for:
Level 1: CRE RECOMBINASE//TET SYSTEM//RTTA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8740 1222 37.8 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
1115 2             GENOME EDITING//CRISPR CAS9//CRISPR 9706
8740 1                   CRE RECOMBINASE//TET SYSTEM//RTTA 1222

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CRE RECOMBINASE authKW 489998 9% 19% 105
2 TET SYSTEM authKW 212627 2% 43% 20
3 RTTA authKW 195881 1% 56% 14
4 TET ON authKW 188795 2% 33% 23
5 GENESIS journal 185975 9% 7% 106
6 LOXP authKW 178429 2% 24% 30
7 TET ON SYSTEM authKW 153618 1% 36% 17
8 CRE TOXICITY authKW 128500 0% 86% 6
9 ICRE RECOMBINASE authKW 124932 0% 100% 5
10 ROSA26 authKW 106444 1% 30% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Genetics & Heredity 5478 28% 0% 347
2 Developmental Biology 5308 14% 0% 165
3 Biochemistry & Molecular Biology 2502 39% 0% 478
4 Biotechnology & Applied Microbiology 2234 19% 0% 233
5 Medicine, Research & Experimental 1394 14% 0% 165
6 Cell Biology 1236 18% 0% 217
7 Biochemical Research Methods 997 10% 0% 126
8 Neurosciences 129 9% 0% 105
9 Biophysics 117 5% 0% 57
10 Cell & Tissue Engineering 94 1% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOL MOUSE GENET 56218 0% 75% 3
2 ACUICULTURA TORRELASAL 49973 0% 100% 2
3 FRANCEINSERM 49973 0% 100% 2
4 FEDERAT 02 44973 0% 60% 3
5 AUSTRALIAN REGENERAT MED EMBL AUSTRALIA 33314 0% 67% 2
6 SECT BIOL CHEM PHARM 33314 0% 67% 2
7 GENET BIOL MOL CELLULAIRE FRANCE 32122 0% 43% 3
8 AIDS DISPARIT 24986 0% 100% 1
9 ANIN OURCES 24986 0% 100% 1
10 ANN ARBOR VET ADM MED GRECC 24986 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENESIS 185975 9% 7% 106
2 TRANSGENIC RESEARCH 13447 2% 2% 30
3 JOURNAL OF GENE MEDICINE 8570 2% 2% 22
4 GENE THERAPY 4962 2% 1% 28
5 MOLECULAR THERAPY 4023 2% 1% 24
6 HUMAN GENE THERAPY 3927 2% 1% 23
7 BIOTECHNIQUES 3189 2% 0% 28
8 NUCLEIC ACIDS RESEARCH 2751 5% 0% 67
9 BMC BIOTECHNOLOGY 1349 1% 1% 8
10 PHYSIOLOGICAL GENOMICS 848 1% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CRE RECOMBINASE 489998 9% 19% 105 Search CRE+RECOMBINASE Search CRE+RECOMBINASE
2 TET SYSTEM 212627 2% 43% 20 Search TET+SYSTEM Search TET+SYSTEM
3 RTTA 195881 1% 56% 14 Search RTTA Search RTTA
4 TET ON 188795 2% 33% 23 Search TET+ON Search TET+ON
5 LOXP 178429 2% 24% 30 Search LOXP Search LOXP
6 TET ON SYSTEM 153618 1% 36% 17 Search TET+ON+SYSTEM Search TET+ON+SYSTEM
7 CRE TOXICITY 128500 0% 86% 6 Search CRE+TOXICITY Search CRE+TOXICITY
8 ICRE RECOMBINASE 124932 0% 100% 5 Search ICRE+RECOMBINASE Search ICRE+RECOMBINASE
9 ROSA26 106444 1% 30% 14 Search ROSA26 Search ROSA26
10 RAT INSULIN PROMOTER RIP 99946 0% 100% 4 Search RAT+INSULIN+PROMOTER+RIP Search RAT+INSULIN+PROMOTER+RIP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LEWANDOSKI, M , (2001) CONDITIONAL CONTROL OF GENE EXPRESSION IN THE MOUSE.NATURE REVIEWS GENETICS. VOL. 2. ISSUE 10. P. 743 -755 66 46% 443
2 STIEGER, K , BELBELLAA, B , LE GUINER, C , MOULLIER, P , ROLLING, F , (2009) IN VIVO GENE REGULATION USING TETRACYCLINE-REGULATABLE SYSTEMS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 61. ISSUE 7-8. P. 527-541 63 48% 56
3 XIAO, D , SUN, Y , GU, WW , CHEN, XG , (2007) TETRACYCLINE-CONTROLLED TRANSCRIPTIONAL REGULATION SYSTEMS: COUNTERMEASURES TO ELIMINATE BASAL TRANSGENE LEAKS IN TET-BASED SYSTEMS.PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL. VOL. 17. ISSUE 1. P. 11-19 45 73% 6
4 GARCIA-OTIN, AL , GUILLOU, F , (2006) MAMMALIAN GENOME TARGETING USING SITE-SPECIFIC RECOMBINASES.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 11. ISSUE . P. 1108-1136 90 33% 49
5 MAY, T , HAUSER, H , WIRTH, D , (2006) CURRENT STATUS OF TRANSCRIPTIONAL REGULATION SYSTEMS.CYTOTECHNOLOGY. VOL. 50. ISSUE 1-3. P. 109-119 48 62% 4
6 BOCKAMP, E , MARINGER, M , SPANGENBERG, C , FEES, S , FRASER, S , ESHKIND, L , OESCH, F , ZABEL, B , (2002) OF MICE AND MODELS: IMPROVED ANIMAL MODELS FOR BIOMEDICAL RESEARCH.PHYSIOLOGICAL GENOMICS. VOL. 11. ISSUE 3. P. 115-132 65 42% 97
7 MALLO, M , (2006) CONTROLLED GENE ACTIVATION AND INACTIVATION IN THE MOUSE.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 11. ISSUE . P. 313-327 53 49% 23
8 BRANDA, CS , DYMECKI, SM , (2004) TALKING ABOUT A REVOLUTION: THE IMPACT OF SITE-SPECIFIC RECOMBINASES ON GENETIC ANALYSES IN MICE.DEVELOPMENTAL CELL. VOL. 6. ISSUE 1. P. 7 -28 53 30% 460
9 HEINZ, N , HENNIG, K , LOEW, R , (2013) GRADED OR THRESHOLD RESPONSE OF THE TET-CONTROLLED GENE EXPRESSION: ALL DEPENDS ON THE CONCENTRATION OF THE TRANSACTIVATOR.BMC BIOTECHNOLOGY. VOL. 13. ISSUE . P. - 29 67% 5
10 RYDING, ADS , SHARP, MGF , MULLINS, JJ , (2001) CONDITIONAL TRANSGENIC TECHNOLOGIES.JOURNAL OF ENDOCRINOLOGY. VOL. 171. ISSUE 1. P. 1-14 55 45% 86

Classes with closest relation at Level 1


Rank Class id link
1 7535 SITE SPECIFIC RECOMBINATION//SERINE RECOMBINASE//PHIC31 INTEGRASE
2 30989 CHEMICALLY INDUCIBLE GENE EXPRESSION//ALC SWITCH//ALC SYSTEM
3 25676 GENE TRAP//GENE TRAPPING//SPLICING AROUND
4 22210 PROTEIN KNOCKDOWN//PROTACS//CHEMICAL INDUCERS OF DIMERIZATION
5 20819 TET REPRESSOR//TETRACYCLINE H ANTIPORTER//TETRACYCLINE RESISTANCE PROTEIN
6 12165 GENE TARGETING//SOMATIC CELL AND MOLECULAR GENETICS//HOMOLOGOUS RECOMBINATION
7 16858 MAMMALIAN GENET UNIT//ENU MUTAGENESIS//PHENOTYPE DRIVEN SCREEN
8 28833 GENETIC RADIOTHERAPY//TNFERADE//CARG ELEMENTS
9 25514 HERPES SIMPLEX VIRUS VECTOR//W ROXBURY VA HOSP//HELPER VIRUS FREE PACKAGING
10 30077 2A PEPTIDE//FMDV 2A//2A

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