Class information for:
Level 1: TET REPRESSOR//TETRACYCLINE H ANTIPORTER//TETRACYCLINE RESISTANCE PROTEIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20819 444 32.9 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
804 2             JOURNAL OF BACTERIOLOGY//PHOSPHOTRANSFERASE SYSTEM//PERIPLASMIC BINDING PROTEIN 12049
20819 1                   TET REPRESSOR//TETRACYCLINE H ANTIPORTER//TETRACYCLINE RESISTANCE PROTEIN 444

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TET REPRESSOR authKW 976859 6% 57% 25
2 TETRACYCLINE H ANTIPORTER authKW 625202 2% 91% 10
3 TETRACYCLINE RESISTANCE PROTEIN authKW 412634 1% 100% 6
4 LEHRSTUHL MIKROBIOL BIOCHEM GENET address 286550 1% 83% 5
5 MIKROBIOL BIOCHEM GENET address 282093 4% 22% 19
6 TET OPERATOR authKW 214910 1% 63% 5
7 MIKROBIOL BIOCHEM address 190440 1% 46% 6
8 TETRACYCLINE REPRESSOR authKW 145628 1% 35% 6
9 ALPHA HELIX TURN ALPHA HELIX authKW 137545 0% 100% 2
10 RECOGNITION SPECIFICITIES authKW 137545 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Microbiology 4107 40% 0% 179
2 Biochemistry & Molecular Biology 1273 45% 0% 201
3 Biophysics 171 8% 0% 36
4 Genetics & Heredity 152 9% 0% 40
5 Pharmacology & Pharmacy 118 12% 0% 53
6 Cell Biology 41 7% 0% 31
7 Biotechnology & Applied Microbiology 33 5% 0% 23
8 Biochemical Research Methods 19 3% 0% 14
9 Infectious Diseases 10 2% 0% 10
10 Chemistry, Medicinal 7 2% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEHRSTUHL MIKROBIOL BIOCHEM GENET 286550 1% 83% 5
2 MIKROBIOL BIOCHEM GENET 282093 4% 22% 19
3 MIKROBIOL BIOCHEM 190440 1% 46% 6
4 CELL MEMBRANE BIOL 127856 3% 12% 15
5 LEHRSTUHL MIKROBIOL 105691 9% 4% 39
6 AGR BIOL OURCES 68772 0% 100% 1
7 LEHRSTUHL MIKROBIOL BIOCHIM GENET 68772 0% 100% 1
8 YA OVCHINNIKOV BIOORGAN CHEM 68772 0% 100% 1
9 ONDEK PTY LTD 45846 0% 33% 2
10 LEHRBEREICH MIKROBIELLE GENET 41259 1% 20% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BACTERIOLOGY 8483 14% 0% 64
2 PLASMID 5722 3% 1% 13
3 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 3332 8% 0% 34
4 JOURNAL OF MOLECULAR BIOLOGY 1816 6% 0% 25
5 ANTIBIOTIKI I MEDITSINSKAYA BIOTEKHNOLOGIYA 1598 1% 1% 3
6 IZVESTIYA AKADEMII NAUK SSSR SERIYA BIOLOGICHESKAYA 1412 1% 0% 5
7 METHODS IN MOLECULAR AND CELLULAR BIOLOGY 1107 0% 2% 1
8 GENE 777 3% 0% 15
9 JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY 765 1% 0% 3
10 JOURNAL OF PROTEIN CHEMISTRY 729 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TET REPRESSOR 976859 6% 57% 25 Search TET+REPRESSOR Search TET+REPRESSOR
2 TETRACYCLINE H ANTIPORTER 625202 2% 91% 10 Search TETRACYCLINE+H+ANTIPORTER Search TETRACYCLINE+H+ANTIPORTER
3 TETRACYCLINE RESISTANCE PROTEIN 412634 1% 100% 6 Search TETRACYCLINE+RESISTANCE+PROTEIN Search TETRACYCLINE+RESISTANCE+PROTEIN
4 TET OPERATOR 214910 1% 63% 5 Search TET+OPERATOR Search TET+OPERATOR
5 TETRACYCLINE REPRESSOR 145628 1% 35% 6 Search TETRACYCLINE+REPRESSOR Search TETRACYCLINE+REPRESSOR
6 ALPHA HELIX TURN ALPHA HELIX 137545 0% 100% 2 Search ALPHA+HELIX+TURN+ALPHA+HELIX Search ALPHA+HELIX+TURN+ALPHA+HELIX
7 RECOGNITION SPECIFICITIES 137545 0% 100% 2 Search RECOGNITION+SPECIFICITIES Search RECOGNITION+SPECIFICITIES
8 REVERSE TETR 137545 0% 100% 2 Search REVERSE+TETR Search REVERSE+TETR
9 TETR INDUCING PEPTIDES 137545 0% 100% 2 Search TETR+INDUCING+PEPTIDES Search TETR+INDUCING+PEPTIDES
10 TETRACYCLINE BINDING 137545 0% 100% 2 Search TETRACYCLINE+BINDING Search TETRACYCLINE+BINDING

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HILLEN, W , BERENS, C , (1994) MECHANISMS UNDERLYING EXPRESSION OF TN10 ENCODED TETRACYCLINE RESISTANCE.ANNUAL REVIEW OF MICROBIOLOGY. VOL. 48. ISSUE . P. 345-369 54 64% 301
2 SCHNAPPINGER, D , HILLEN, W , (1996) TETRACYCLINES: ANTIBIOTIC ACTION, UPTAKE, AND RESISTANCE MECHANISMS.ARCHIVES OF MICROBIOLOGY. VOL. 165. ISSUE 6. P. 359-369 53 51% 166
3 JIN, H , KRULWICH, TA , (2002) SITE-DIRECTED MUTAGENESIS STUDIES OF SELECTED MOTIF AND CHARGED RESIDUES AND OF CYSTEINES OF THE MULTIFUNCTIONAL TETRACYCLINE EFFLUX PROTEIN TET(L).JOURNAL OF BACTERIOLOGY. VOL. 184. ISSUE 6. P. 1796 -1800 29 88% 3
4 WERTEN, S , SCHNEIDER, J , PALM, GJ , HINRICHS, W , (2016) MODULAR ORGANISATION OF INDUCER RECOGNITION AND ALLOSTERY IN THE TETRACYCLINE REPRESSOR.FEBS JOURNAL. VOL. 283. ISSUE 11. P. 2102 -2114 22 71% 0
5 KRULWICH, TA , JIN, J , GUFFANTI, AA , BECHHOFER, DH , (2001) FUNCTIONS OF TETRACYCLINE EFFLUX PROTEINS THAT DO NOT INVOLVE TETRACYCLINE.JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 3. ISSUE 2. P. 237-246 39 57% 18
6 POOK, E , GRIMM, S , BONIN, A , WINKLER, T , HILLEN, W , (1998) AFFINITIES OF MABS TO TET REPRESSOR COMPLEXED WITH OPERATOR OR TETRACYCLINE SUGGEST CONFORMATIONAL CHANGES ASSOCIATED WITH INDUCTION.EUROPEAN JOURNAL OF BIOCHEMISTRY. VOL. 258. ISSUE 3. P. 915-922 25 96% 3
7 GUAY, GG , ROTHSTEIN, DM , (1993) EXPRESSION OF THE TETK GENE FROM STAPHYLOCOCCUS-AUREUS IN ESCHERICHIA-COLI - COMPARISON OF SUBSTRATE SPECIFICITIES OF TETA(B), TETA(C), AND TETK EFFLUX PROTEINS.ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. VOL. 37. ISSUE 2. P. 191-198 33 83% 25
8 MCNICHOLAS, P , CHOPRA, I , ROTHSTEIN, DM , (1992) GENETIC-ANALYSIS OF THE TETA(C) GENE ON PLASMID PBR322.JOURNAL OF BACTERIOLOGY. VOL. 174. ISSUE 24. P. 7926-7933 32 86% 33
9 MCMURRY, LM , ALDEMA-RAMOS, ML , LEVY, SB , (2002) FE2+-TETRACYCLINE-MEDIATED CLEAVAGE OF THE TN10 TETRACYCLINE EFFLUX PROTEIN TETA REVEALS A SUBSTRATE BINDING SITE NEAR GLUTAMINE 225 IN TRANSMEMBRANE HELIX 7.JOURNAL OF BACTERIOLOGY. VOL. 184. ISSUE 18. P. 5113 -5120 31 63% 4
10 SARACENI-RICHARDS, CA , LEVY, SB , (2000) EVIDENCE FOR INTERACTIONS BETWEEN HELICES 5 AND 8 AND A ROLE FOR THE INTERDOMAIN LOOP IN TETRACYCLINE RESISTANCE MEDIATED BY HYBRID TET PROTEINS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 275. ISSUE 9. P. 6101-6106 26 79% 6

Classes with closest relation at Level 1


Rank Class id link
1 28777 TETRACYCLINE DERIVATIVES//5A 6 ANHYDROTETRACYCLINE//ACETYLCUPREINE
2 30447 5 N N DIMETHYLAMILORIDE//BASELINE MIC CREEP//BENZAMIL HCL
3 10521 LACTOSE PERMEASE//PHYSIOL MICROBIOL//MACDONALD S 5 748
4 30989 CHEMICALLY INDUCIBLE GENE EXPRESSION//ALC SWITCH//ALC SYSTEM
5 3970 EFFLUX PUMP INHIBITOR//EFFLUX PUMPS//EMRE
6 18319 TN916//CONJUGATIVE TRANSPOSON//NWFIII MIKROBIOL
7 15552 TIGECYCLINE//GLYCYLCYCLINE//GAR 936
8 12264 PLASMID//ROLLING CIRCLE REPLICATION//CRYPTIC PLASMID
9 8740 CRE RECOMBINASE//TET SYSTEM//RTTA
10 25273 CMLA//CAPTURE ELEMENT//CATB7

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