Class information for:
Level 1: IFOSFAMIDE//MESNA//TROFOSFAMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6772 1445 30.1 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
2496 2             IFOSFAMIDE//CHEMOSENSITIVITY TEST//MESNA 3914
6772 1                   IFOSFAMIDE//MESNA//TROFOSFAMIDE 1445

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IFOSFAMIDE authKW 1615886 19% 28% 269
2 MESNA authKW 559028 4% 42% 63
3 TROFOSFAMIDE authKW 432835 2% 79% 26
4 BNP7787 authKW 338081 1% 100% 16
5 OXAZAPHOSPHORINES authKW 327718 2% 57% 27
6 CHLOROACETALDEHYDE authKW 317300 2% 52% 29
7 GLUFOSFAMIDE authKW 300513 1% 89% 16
8 ISOPHOSPHORAMIDE MUSTARD authKW 192090 1% 91% 10
9 4 HYDROXYCYCLOPHOSPHAMIDE authKW 178977 1% 71% 12
10 DIMESNA authKW 147910 0% 100% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 10140 44% 0% 630
2 Pharmacology & Pharmacy 5432 37% 0% 529
3 Chemistry, Medicinal 807 8% 0% 111
4 Chemistry, Analytical 429 9% 0% 127
5 Toxicology 308 5% 0% 74
6 Pediatrics 244 5% 0% 79
7 Biochemical Research Methods 184 5% 0% 68
8 Hematology 145 4% 0% 56
9 Urology & Nephrology 83 3% 0% 43
10 Medical Laboratory Technology 44 1% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NIOMECH 63390 0% 100% 3
2 CIHR GSK CHAIR PAEDIAT CLIN PHARMACOL 48017 0% 45% 5
3 CLIN PHARMACOL BIOANAL 47541 0% 75% 3
4 KRIGO 47541 0% 75% 3
5 CLIN PHARMACOL TOXICOL PHARMACOKINET 42260 0% 100% 2
6 METAB MALAD METAB U820 28172 0% 67% 2
7 SLOTERVAART HOSP 23372 1% 8% 14
8 ALLOGENE STEM CELL TRANSPLANTA 21130 0% 100% 1
9 BRADFORT NHS TRUST BEATSON ONCOL 21130 0% 100% 1
10 CANC 441 KOMATSUSHIMA AOBA KU 21130 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 38710 8% 2% 116
2 SEMINARS IN ONCOLOGY 4644 2% 1% 34
3 CANCER TREATMENT REVIEWS 4319 1% 1% 20
4 ANTI-CANCER DRUGS 3692 2% 1% 24
5 NORTH DAKOTA COOPERATIVE EXTENSION SERVICE CIRCULAR 3520 0% 17% 1
6 DRUG METABOLISM AND DISPOSITION 3203 2% 0% 34
7 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 3164 2% 1% 27
8 INVESTIGATIONAL NEW DRUGS 2957 1% 1% 19
9 MEDICAL AND PEDIATRIC ONCOLOGY 2709 1% 1% 18
10 CANCER TREATMENT REPORTS 2131 1% 1% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IFOSFAMIDE 1615886 19% 28% 269 Search IFOSFAMIDE Search IFOSFAMIDE
2 MESNA 559028 4% 42% 63 Search MESNA Search MESNA
3 TROFOSFAMIDE 432835 2% 79% 26 Search TROFOSFAMIDE Search TROFOSFAMIDE
4 BNP7787 338081 1% 100% 16 Search BNP7787 Search BNP7787
5 OXAZAPHOSPHORINES 327718 2% 57% 27 Search OXAZAPHOSPHORINES Search OXAZAPHOSPHORINES
6 CHLOROACETALDEHYDE 317300 2% 52% 29 Search CHLOROACETALDEHYDE Search CHLOROACETALDEHYDE
7 GLUFOSFAMIDE 300513 1% 89% 16 Search GLUFOSFAMIDE Search GLUFOSFAMIDE
8 ISOPHOSPHORAMIDE MUSTARD 192090 1% 91% 10 Search ISOPHOSPHORAMIDE+MUSTARD Search ISOPHOSPHORAMIDE+MUSTARD
9 4 HYDROXYCYCLOPHOSPHAMIDE 178977 1% 71% 12 Search 4+HYDROXYCYCLOPHOSPHAMIDE Search 4+HYDROXYCYCLOPHOSPHAMIDE
10 DIMESNA 147910 0% 100% 7 Search DIMESNA Search DIMESNA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KERBUSCH, T , DE KRAKER, J , KEIZER, HJ , VAN PUTTEN, JWG , GROEN, HJM , JANSEN, RLH , SCHELLENS, JHM , BEIJNEN, JH , (2001) CLINICAL PHARMACOKINETICS AND PHARMACODYNAMICS OF IFOSFAMIDE AND ITS METABOLITES.CLINICAL PHARMACOKINETICS. VOL. 40. ISSUE 1. P. 41 -62 132 81% 62
2 GIRAUD, B , HEBERT, G , DEROUSSENT, A , VEAL, GJ , VASSAL, G , PACI, A , (2010) OXAZAPHOSPHORINES: NEW THERAPEUTIC STRATEGIES FOR AN OLD CLASS OF DRUGS.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 6. ISSUE 8. P. 919 -938 96 73% 24
3 ZHANG, J , TIAN, Q , CHAN, SY , LI, SC , ZHOU, SF , DUAN, W , ZHU, YZ , (2005) METABOLISM AND TRANSPORT OF OXAZAPHOSPHORINES AND THE CLINICAL IMPLICATIONS.DRUG METABOLISM REVIEWS. VOL. 37. ISSUE 4. P. 611 -703 196 36% 95
4 DE JONGE, ME , HUITEMA, ADR , RODENHUIS, S , BEIJNEN, JH , (2005) CLINICAL PHARMACOKINETICS OF CYCLOPHOSPHAMIDE.CLINICAL PHARMACOKINETICS. VOL. 44. ISSUE 11. P. 1135-1164 104 64% 116
5 BAUMANN, F , PREISS, R , (2001) CYCLOPHOSPHAMIDE AND RELATED ANTICANCER DRUGS.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 764. ISSUE 1-2. P. 173 -192 93 73% 57
6 WAGNER, T , (1994) IFOSFAMIDE CLINICAL PHARMACOKINETICS.CLINICAL PHARMACOKINETICS. VOL. 26. ISSUE 6. P. 439-456 77 88% 69
7 BODDY, AV , YULE, SM , (2000) METABOLISM AND PHARMACOKINETICS OF OXAZAPHOSPHORINES.CLINICAL PHARMACOKINETICS. VOL. 38. ISSUE 4. P. 291 -304 72 67% 105
8 ZHANG, J , TIAN, Q , ZHU, YZ , XU, AL , ZHOU, SF , (2006) REVERSAL OF RESISTANCE TO OXAZAPHOSPHORINES.CURRENT CANCER DRUG TARGETS. VOL. 6. ISSUE 5. P. 385-407 112 41% 6
9 HANLY, L , CHEN, N , RIEDER, M , KOREN, G , (2009) IFOSFAMIDE NEPHROTOXICITY IN CHILDREN: A MECHANISTIC BASE FOR PHARMACOLOGICAL PREVENTION.EXPERT OPINION ON DRUG SAFETY. VOL. 8. ISSUE 2. P. 155-168 59 68% 15
10 AJITHKUMAR, T , PARKINSON, C , SHAMSHAD, F , MURRAY, P , (2007) IFOSFAMIDE ENCEPHALOPATHY.CLINICAL ONCOLOGY. VOL. 19. ISSUE 2. P. 108-114 41 95% 32

Classes with closest relation at Level 1


Rank Class id link
1 27547 THIOTEPA//THIOTEPA MERCAPTURATE//N N N TRIETHYLENEPHOSPHORAMIDE
2 11645 TRABECTEDIN//ET 743//SOFT TISSUE SARCOMA
3 20094 MELPHALAN//CHLORAMBUCIL//PREDNIMUSTINE
4 10766 ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE
5 18310 ACROLEIN//AMINE PHARMA//PROTEIN CONJUGATED ACROLEIN
6 29622 CLIN PHARMACOL PHARMACO EPIDEMIOL//METHYLTHIONINIUM CHLORIDE//FUNCT LIPID BRANCH
7 37538 HETEROCYCLIC TRIOXIRANES//TEROXIRONE//HUMAN NON SMALL CELL LUNG CANCER CELLS
8 3335 CISPLATIN//NEPHROTOXICITY//CISPLATIN NEPHROTOXICITY
9 13800 ANTINEOPLASTIC DRUGS//HAZARDOUS DRUGS//TOXICITY ENVIRONMENTAL
10 4703 BK VIRUS//HEMORRHAGIC CYSTITIS//POLYOMAVIRUS

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