Class information for:
Level 1: ACROLEIN//AMINE PHARMA//PROTEIN CONJUGATED ACROLEIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18310 557 45.2 75%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
456 3       VIRGIN OLIVE OIL//OLIVE OIL//HYDROXYTYROSOL 25234
1344 2             4 HYDROXYNONENAL//ACROLEIN//LIPID OXIDATION 8319
18310 1                   ACROLEIN//AMINE PHARMA//PROTEIN CONJUGATED ACROLEIN 557

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACROLEIN authKW 2901752 38% 25% 211
2 AMINE PHARMA address 595753 4% 45% 24
3 PROTEIN CONJUGATED ACROLEIN authKW 274100 1% 100% 5
4 3 HYDROXYPROPYLMERCAPTURIC ACID authKW 228415 1% 83% 5
5 BIOFUNCT SYNTHET CHEM address 221093 2% 37% 11
6 BEIJING WORK STN address 219280 1% 100% 4
7 PROALGESIC authKW 164460 1% 100% 3
8 FOOD BIODYNAM address 131734 4% 10% 25
9 A BUTLEROV CHEM address 125291 1% 29% 8
10 2 PROPENAL authKW 123343 1% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 7290 34% 0% 191
2 Pharmacology & Pharmacy 414 18% 0% 100
3 Biochemistry & Molecular Biology 334 24% 0% 132
4 Chemistry, Medicinal 149 6% 0% 31
5 Neurosciences 59 9% 0% 48
6 Food Science & Technology 47 4% 0% 25
7 Peripheral Vascular Diseases 39 3% 0% 18
8 Biophysics 38 4% 0% 23
9 Medical Laboratory Technology 37 2% 0% 9
10 Respiratory System 35 3% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMINE PHARMA 595753 4% 45% 24
2 BIOFUNCT SYNTHET CHEM 221093 2% 37% 11
3 BEIJING WORK STN 219280 1% 100% 4
4 FOOD BIODYNAM 131734 4% 10% 25
5 A BUTLEROV CHEM 125291 1% 29% 8
6 CFGBC 109640 0% 100% 2
7 PARALYSIS 93559 2% 13% 13
8 PHARMACOL ANAESTHESIOL UNIT 73992 2% 15% 9
9 BIOFUCT CHEM 54820 0% 100% 1
10 CANC PHARMACEUT SCI 54820 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEMICAL RESEARCH IN TOXICOLOGY 5553 4% 0% 23
2 TOXICOLOGY 3781 4% 0% 22
3 MOLECULAR NUTRITION & FOOD RESEARCH 3534 2% 1% 12
4 MOLECULAR & CELLULAR TOXICOLOGY 3391 1% 1% 6
5 BIOCHIP JOURNAL 3036 1% 1% 5
6 TOXICOLOGY LETTERS 2604 4% 0% 20
7 TOXICOLOGY AND APPLIED PHARMACOLOGY 2436 4% 0% 21
8 FREE RADICAL BIOLOGY AND MEDICINE 1415 3% 0% 15
9 CHEMICO-BIOLOGICAL INTERACTIONS 1157 2% 0% 11
10 ANNALES DE L ANESTHESIOLOGIE FRANCAISE 1117 0% 2% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ACROLEIN 2901752 38% 25% 211 Search ACROLEIN Search ACROLEIN
2 PROTEIN CONJUGATED ACROLEIN 274100 1% 100% 5 Search PROTEIN+CONJUGATED+ACROLEIN Search PROTEIN+CONJUGATED+ACROLEIN
3 3 HYDROXYPROPYLMERCAPTURIC ACID 228415 1% 83% 5 Search 3+HYDROXYPROPYLMERCAPTURIC+ACID Search 3+HYDROXYPROPYLMERCAPTURIC+ACID
4 PROALGESIC 164460 1% 100% 3 Search PROALGESIC Search PROALGESIC
5 2 PROPENAL 123343 1% 75% 3 Search 2+PROPENAL Search 2+PROPENAL
6 ACROLEIN LYSINE ADDUCT 123343 1% 75% 3 Search ACROLEIN+LYSINE+ADDUCT Search ACROLEIN+LYSINE+ADDUCT
7 ACROLEIN TOXICITY DECREASING CELLS 109640 0% 100% 2 Search ACROLEIN+TOXICITY+DECREASING+CELLS Search ACROLEIN+TOXICITY+DECREASING+CELLS
8 ALDEHYDE LOAD 109640 0% 100% 2 Search ALDEHYDE+LOAD Search ALDEHYDE+LOAD
9 CARBOXYL STRESS 109640 0% 100% 2 Search CARBOXYL+STRESS Search CARBOXYL+STRESS
10 FDP LYSINE 109640 0% 100% 2 Search FDP+LYSINE Search FDP+LYSINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MOGHE, A , GHARE, S , LAMOREAU, B , MOHAMMAD, M , BARVE, S , MCCLAIN, C , JOSHI-BARVE, S , (2015) MOLECULAR MECHANISMS OF ACROLEIN TOXICITY: RELEVANCE TO HUMAN DISEASE.TOXICOLOGICAL SCIENCES. VOL. 143. ISSUE 2. P. 242 -255 80 57% 21
2 ALDINI, G , ORIOLI, M , CARINI, M , (2011) PROTEIN MODIFICATION BY ACROLEIN: RELEVANCE TO PATHOLOGICAL CONDITIONS AND INHIBITION BY ALDEHYDE SEQUESTERING AGENTS.MOLECULAR NUTRITION & FOOD RESEARCH. VOL. 55. ISSUE 9. P. 1301 -1319 71 56% 30
3 HIGASHI, K , IGARASHI, K , TOIDA, T , (2016) RECENT PROGRESS IN ANALYTICAL METHODS FOR DETERMINATION OF URINARY 3-HYDROXYPROPYLMERCAPTURIC ACID, A MAJOR METABOLITE OF ACROLEIN.BIOLOGICAL & PHARMACEUTICAL BULLETIN. VOL. 39. ISSUE 6. P. 915 -919 32 82% 0
4 TANEL, A , PALLEPATI, P , BETTAIEB, A , MORIN, P , AVERILL-BATES, DA , (2014) ACROLEIN ACTIVATES CELL SURVIVAL AND APOPTOTIC DEATH RESPONSES INVOLVING THE ENDOPLASMIC RETICULUM IN A549 LUNG CELLS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1843. ISSUE 5. P. 827 -835 38 62% 7
5 YEAGER, RP , KUSHMAN, M , CHEMERYNSKI, S , WEIL, R , FU, X , WHITE, M , CALLAHAN-LYON, P , ROSENFELDT, H , (2016) PROPOSED MODE OF ACTION FOR ACROLEIN RESPIRATORY TOXICITY ASSOCIATED WITH INHALED TOBACCO SMOKE.TOXICOLOGICAL SCIENCES. VOL. 151. ISSUE 2. P. 347 -364 52 41% 1
6 TAKAMATSU, M , FUKASE, K , OKA, R , KITAZUME, S , TANIGUCHI, N , TANAKA, K , (2016) A REDUCTION-BASED SENSOR FOR ACROLEIN CONJUGATES WITH THE INEXPENSIVE NITROBENZENE AS AN ALTERNATIVE TO MONOCLONAL ANTIBODY.SCIENTIFIC REPORTS. VOL. 6. ISSUE . P. - 33 63% 0
7 ZHU, Q , SUN, Z , JIANG, Y , CHEN, F , WANG, MF , (2011) ACROLEIN SCAVENGERS: REACTIVITY, MECHANISM AND IMPACT ON HEALTH.MOLECULAR NUTRITION & FOOD RESEARCH. VOL. 55. ISSUE 9. P. 1375-1390 50 38% 18
8 TULLY, M , ZHENG, LX , SHI, RY , (2014) ACROLEIN DETECTION: POTENTIAL THERANOSTIC UTILITY IN MULTIPLE SCLEROSIS AND SPINAL CORD INJURY.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 14. ISSUE 6. P. 679-685 27 66% 2
9 ABRAHAM, K , ANDRES, S , PALAVINSKAS, R , BERG, K , APPEL, KE , LAMPEN, A , (2011) TOXICOLOGY AND RISK ASSESSMENT OF ACROLEIN IN FOOD.MOLECULAR NUTRITION & FOOD RESEARCH. VOL. 55. ISSUE 9. P. 1277 -1290 38 44% 22
10 HAMANN, K , SHI, RY , (2009) ACROLEIN SCAVENGING: A POTENTIAL NOVEL MECHANISM OF ATTENUATING OXIDATIVE STRESS FOLLOWING SPINAL CORD INJURY.JOURNAL OF NEUROCHEMISTRY. VOL. 111. ISSUE 6. P. 1348 -1356 34 50% 36

Classes with closest relation at Level 1


Rank Class id link
1 12584 ETHENO DNA ADDUCTS//ETHENO ADDUCTS//TOXICOL CANC RISK TORS
2 7185 4 HYDROXYNONENAL//4 HYDROXY 2 NONENAL//HNE
3 6772 IFOSFAMIDE//MESNA//TROFOSFAMIDE
4 23812 SENSORY IRRITATION//CHEMOSENSORY PERCEPT//NASAL PUNGENCY
5 2297 CIGARETTE SMOKE//EMPHYSEMA//CHRONIC OBSTRUCTIVE PULMONARY DISEASE
6 18428 PARALYSIS//MEMBRANE SEALING//CRAYFISH MEDIAL GIANT AXON
7 5612 FORMALDEHYDE//2 4 DINITROPHENYLHYDRAZINE//FORMALDEHYDE DETERMINATION
8 27448 8 HYDROXRGUANIN//APEL REF1//ARTERIAL CHANGE
9 19918 SESBANIA GRANDIFLORA//CIGARETTE SMOKE//OXIDATIVE DAMAGE OF PROTEINS
10 15943 TRICHLOROMETHYLPEROXYL//TRICHLOROMETHYL//CELL SURFACE BLEBS

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