Class information for:
Level 1: THIOTEPA//THIOTEPA MERCAPTURATE//N N N TRIETHYLENEPHOSPHORAMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
27547 227 25.1 41%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
2496 2             IFOSFAMIDE//CHEMOSENSITIVITY TEST//MESNA 3914
27547 1                   THIOTEPA//THIOTEPA MERCAPTURATE//N N N TRIETHYLENEPHOSPHORAMIDE 227

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THIOTEPA authKW 510818 11% 15% 26
2 THIOTEPA MERCAPTURATE authKW 403551 1% 100% 3
3 N N N TRIETHYLENEPHOSPHORAMIDE authKW 302662 1% 75% 3
4 MONOCHLOROTEPA authKW 269034 1% 100% 2
5 RARE TAUTOMERIC FORMS authKW 269034 1% 100% 2
6 SODIUM CHLORIDE CATALYZED DEGRADATION authKW 269034 1% 100% 2
7 THIOTEPA AND TEPA authKW 269034 1% 100% 2
8 N N N TRIETHYLENETHIOPHOSPHORAMIDE authKW 242128 1% 60% 3
9 TEPA authKW 210540 3% 26% 6
10 SPECTROFLUORIMETRIC METHODS authKW 179355 1% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 522 26% 0% 59
2 Pharmacology & Pharmacy 261 22% 0% 49
3 Biophysics 94 8% 0% 19
4 Virology 91 5% 0% 12
5 Toxicology 52 5% 0% 12
6 Biochemistry & Molecular Biology 34 15% 0% 33
7 Spectroscopy 33 4% 0% 9
8 Chemistry, Analytical 32 7% 0% 15
9 Chemistry, Multidisciplinary 31 11% 0% 24
10 Chemistry, Organic 18 6% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HOSP ITALIANO CORDOBA 134517 0% 100% 1
2 PHARM PHARAMCOL 134517 0% 100% 1
3 PEDIAT EMATOL ONCOL 4 67258 0% 50% 1
4 PUBL HLTH DANA FARBER CANC 33628 0% 25% 1
5 REPROD MED DEV 33628 0% 25% 1
6 SLOTERVAART HOSP 27348 3% 3% 6
7 SAIC FREDRICK INC 26902 0% 20% 1
8 STUDY LIVER GASTROINTESTINAL DIS CIBEREHD 26902 0% 20% 1
9 VIRAL PROD METHODS DEV 19215 0% 14% 1
10 MOL GENET RADIOBIOL 14539 1% 5% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARBOHYDRATES-NUCLEOSIDES-NUCLEOTIDES 9273 1% 3% 2
2 KHIMIKO-FARMATSEVTICHESKII ZHURNAL 7566 5% 0% 12
3 CANCER BIOTHERAPY 5660 1% 2% 2
4 UKRAINSKII FIZICHESKII ZHURNAL 4079 4% 0% 10
5 CANCER CHEMOTHERAPY AND PHARMACOLOGY 3583 6% 0% 14
6 BIOFIZIKA 2597 4% 0% 9
7 BIOORGANICHESKAYA KHIMIYA 2014 3% 0% 7
8 MOLECULAR BIOLOGY 1024 3% 0% 6
9 CANCER TREATMENT REPORTS 970 2% 0% 4
10 BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY 736 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 THIOTEPA 510818 11% 15% 26 Search THIOTEPA Search THIOTEPA
2 THIOTEPA MERCAPTURATE 403551 1% 100% 3 Search THIOTEPA+MERCAPTURATE Search THIOTEPA+MERCAPTURATE
3 N N N TRIETHYLENEPHOSPHORAMIDE 302662 1% 75% 3 Search N+N+N+TRIETHYLENEPHOSPHORAMIDE Search N+N+N+TRIETHYLENEPHOSPHORAMIDE
4 MONOCHLOROTEPA 269034 1% 100% 2 Search MONOCHLOROTEPA Search MONOCHLOROTEPA
5 RARE TAUTOMERIC FORMS 269034 1% 100% 2 Search RARE+TAUTOMERIC+FORMS Search RARE+TAUTOMERIC+FORMS
6 SODIUM CHLORIDE CATALYZED DEGRADATION 269034 1% 100% 2 Search SODIUM+CHLORIDE+CATALYZED+DEGRADATION Search SODIUM+CHLORIDE+CATALYZED+DEGRADATION
7 THIOTEPA AND TEPA 269034 1% 100% 2 Search THIOTEPA+AND+TEPA Search THIOTEPA+AND+TEPA
8 N N N TRIETHYLENETHIOPHOSPHORAMIDE 242128 1% 60% 3 Search N+N+N+TRIETHYLENETHIOPHOSPHORAMIDE Search N+N+N+TRIETHYLENETHIOPHOSPHORAMIDE
9 TEPA 210540 3% 26% 6 Search TEPA Search TEPA
10 SPECTROFLUORIMETRIC METHODS 179355 1% 67% 2 Search SPECTROFLUORIMETRIC+METHODS Search SPECTROFLUORIMETRIC+METHODS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VAN MAANEN, MJ , SMEETS, CJM , BEIJNEN, JH , (2000) CHEMISTRY, PHARMACOLOGY AND PHARMACOKINETICS OF N,N ',N ''-TRIETHYLENETHIOPHOSPHORAMIDE (THIOTEPA).CANCER TREATMENT REVIEWS. VOL. 26. ISSUE 4. P. 257 -268 49 64% 18
2 HUITEMA, ADR , MATHOT, RAA , TIBBEN, MM , SCHELLENS, JHM , RODENHUIS, S , BEIJNEN, JH , (2001) POPULATION PHARMACOKINETICS OF THIOTEPA AND ITS ACTIVE METABOLITE TEPA IN PATIENTS UNDERGOING HIGH-DOSE CHEMOTHERAPY.BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 51. ISSUE 1. P. 61 -70 22 73% 9
3 VAN MAANEN, MJ , TIJHOF, IM , DAMEN, JMA , VERSLUIS, C , VAN DEN BOSCH, JJK , HECK, AJR , RODENHUIS, S , BEIJNEN, JH , (1999) A SEARCH FOR NEW METABOLITES OF N,N ',N ''-TRIETHYLENETHIOPHOSPHORAMIDE.CANCER RESEARCH. VOL. 59. ISSUE 18. P. 4720-4724 17 77% 8
4 VAN MAANEN, RJ , TIJHOF, IM , DAMEN, JMA , ZWIKKER, JW , BEIJNEN, JH , (2000) THE DEGRADATION OF N,N ',N ''-TRIETHYLENEPHOSPHORAMIDE IN AQUEOUS SOLUTIONS: A QUALITATIVE AND KINETIC STUDY.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 196. ISSUE 1. P. 85-94 12 92% 1
5 VAN MAANEN, RJ , VAN OOIJEN, RD , ZWIKKER, JW , HUITEMA, ADR , RODENHUIS, S , BEIJNEN, JH , (1998) DETERMINATION OF N,N ',N ''-TRIETHYLENETHIOPHOSPHORAMIDE AND ITS ACTIVE METABOLITE N,N ',N ''-TRIETHYLENEPHOSPHORAMIDE IN PLASMA AND URINE USING CAPILLARY GAS CHROMATOGRAPHY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 719. ISSUE 1-2. P. 103-112 15 79% 2
6 LI, F , PATTERSON, AD , HOFER, CC , KRAUSZ, KW , GONZALEZ, FJ , IDLE, JR , (2011) A COMPREHENSIVE UNDERSTANDING OF THIOTEPA METABOLISM IN THE MOUSE USING UPLC-ESI-QTOFMS-BASED METABOLOMICS.BIOCHEMICAL PHARMACOLOGY. VOL. 81. ISSUE 8. P. 1043 -1053 17 46% 8
7 GREBNEVA, EA , TOLPYGO, KB , (1997) VIBRATIONS OF A HYDROGEN-BONDED BASE PAIR POLY(DG)-POLY(DC).ZHURNAL FIZICHESKOI KHIMII. VOL. 71. ISSUE 5. P. 920-925 12 92% 0
8 PRZEPIORKA, D , MADDEN, T , IPPOLITI, C , ESTROV, Z , DIMOPOULOS, M , (1995) DOSING OF THIOTEPA FOR MYELOABLATIVE THERAPY.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 37. ISSUE 1-2. P. 155-160 15 63% 27
9 JACOBSON, PA , GREEN, K , BIRNBAUM, A , REMMEL, RP , (2002) CYTOCHROME P450 ISOZYMES 3A4 AND 2B6 ARE INVOLVED IN THE IN VITRO HUMAN METABOLISM OF THIOTEPA TO TEPA.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 49. ISSUE 6. P. 461-467 17 43% 33
10 VAN MAANEN, MJ , SMITS, KD , BEIJNEN, JH , (2000) SIMULTANEOUS DETERMINATION OF THIOTEPA, TEPA AND A NOVEL, RECENTLY IDENTIFIED THIOTEPA METABOLITE, MONOCHLOROTEPA, IN URINE USING CAPILLARY GAS CHROMATOGRAPHY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 742. ISSUE 2. P. 335-343 9 90% 0

Classes with closest relation at Level 1


Rank Class id link
1 6772 IFOSFAMIDE//MESNA//TROFOSFAMIDE
2 4558 HIGH DOSE CHEMOTHERAPY//DOSE INTENSITY//HIGH RISK BREAST CANCER
3 35771 MACOM//NVPVID400//R 2 AMINO 1 PHENYL 1 C 14ETHANOL
4 31462 CELL MED//H1 CELLS//L15F10 MEDIUM
5 21187 HETERO ASSOCIATION//NOVATRONE//STACKING COMPLEXES
6 13850 BUSULFAN//TREOSULFAN//BU
7 35043 ALKYLPHENOL ETHYLENE OXIDE SURFACTANTS//CHLORHEXIDINE PHOSPHATIDYLCHOLINE NONIONIC TENZIDE COMPLEX//CYCLODEXTRIN INTERACTION
8 36249 AITIMUTAGENICITY//AUTOTROPHIC AND HETEROTROPHIC ORGANISMS//BULGARIA PLANT PHYSIOL GENET
9 37618 NBD GLUCOSAMINE//TUMOR SPECIFIC DOSE//MED HARVARD STUDY KIDNEY DIS
10 20094 MELPHALAN//CHLORAMBUCIL//PREDNIMUSTINE

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