Class information for:
Level 1: TRABECTEDIN//ET 743//SOFT TISSUE SARCOMA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11645 965 36.3 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
409 3       BERBERINE//ALKALOIDS//RUTACEAE 29426
2345 2             AMARYLLIDACEAE//TRABECTEDIN//AMARYLLIDACEAE ALKALOIDS 4395
11645 1                   TRABECTEDIN//ET 743//SOFT TISSUE SARCOMA 965

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRABECTEDIN authKW 3726314 16% 76% 155
2 ET 743 authKW 1023954 4% 83% 39
3 SOFT TISSUE SARCOMA authKW 972392 24% 13% 234
4 ADVANCED SOFT TISSUE SARCOMA authKW 444955 2% 94% 15
5 YONDELIS authKW 263675 1% 83% 10
6 PM00104 authKW 256293 1% 90% 9
7 ECTEINASCIDIN 743 authKW 238514 1% 54% 14
8 ADULT SARCOMA MED TREATMENT UNIT address 189848 1% 100% 6
9 SARCOMA UNIT address 177973 3% 18% 32
10 METASTATIC SOFT TISSUE SARCOMA authKW 168748 1% 67% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 23524 79% 0% 764
2 Pharmacology & Pharmacy 951 20% 0% 195
3 Health Policy & Services 195 3% 0% 25
4 Health Care Sciences & Services 152 3% 0% 30
5 Hematology 70 3% 0% 33
6 Economics 19 3% 0% 25
7 Obstetrics & Gynecology 2 1% 0% 13
8 Transplantation 2 1% 0% 7
9 Chemistry, Medicinal 2 1% 0% 12
10 Toxicology 2 1% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADULT SARCOMA MED TREATMENT UNIT 189848 1% 100% 6
2 SARCOMA UNIT 177973 3% 18% 32
3 POLIGONO IND LA MINA 79098 1% 50% 5
4 ADULT SARCOMA MED ONCOL UNIT 77875 1% 31% 8
5 CLIN RD 77146 2% 13% 19
6 ADULT SARCOMA MED UNIT 63283 0% 100% 2
7 COMPREHENS CANC MUSCULOSKELETAL TUMORS 63283 0% 100% 2
8 METHODOL CLIN PLATFORM 63283 0% 100% 2
9 MUSCULOSKELETAL TUMOR BOARD EXCELLENCE SEVILLA MU 63283 0% 100% 2
10 SARCOMA DIS SITE GRP 63283 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVESTIGATIONAL NEW DRUGS 11121 3% 1% 30
2 CANCER CHEMOTHERAPY AND PHARMACOLOGY 10734 5% 1% 50
3 EUROPEAN JOURNAL OF CANCER 10270 6% 1% 57
4 PHARMACOECONOMICS 8956 3% 1% 25
5 ANNALS OF ONCOLOGY 8820 5% 1% 48
6 EXPERT REVIEW OF ANTICANCER THERAPY 6219 2% 1% 18
7 CANCER TREATMENT REPORTS 5154 2% 1% 19
8 ANTI-CANCER DRUGS 4661 2% 1% 22
9 CURRENT OPINION IN ONCOLOGY 4424 1% 1% 14
10 JOURNAL OF CLINICAL ONCOLOGY 4262 5% 0% 47

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRABECTEDIN 3726314 16% 76% 155 Search TRABECTEDIN Search TRABECTEDIN
2 ET 743 1023954 4% 83% 39 Search ET+743 Search ET+743
3 SOFT TISSUE SARCOMA 972392 24% 13% 234 Search SOFT+TISSUE+SARCOMA Search SOFT+TISSUE+SARCOMA
4 ADVANCED SOFT TISSUE SARCOMA 444955 2% 94% 15 Search ADVANCED+SOFT+TISSUE+SARCOMA Search ADVANCED+SOFT+TISSUE+SARCOMA
5 YONDELIS 263675 1% 83% 10 Search YONDELIS Search YONDELIS
6 PM00104 256293 1% 90% 9 Search PM00104 Search PM00104
7 ECTEINASCIDIN 743 238514 1% 54% 14 Search ECTEINASCIDIN+743 Search ECTEINASCIDIN+743
8 METASTATIC SOFT TISSUE SARCOMA 168748 1% 67% 8 Search METASTATIC+SOFT+TISSUE+SARCOMA Search METASTATIC+SOFT+TISSUE+SARCOMA
9 ZALYPSIS 158207 1% 100% 5 Search ZALYPSIS Search ZALYPSIS
10 HIGH DOSE IFOSFAMIDE 158197 1% 50% 10 Search HIGH+DOSE+IFOSFAMIDE Search HIGH+DOSE+IFOSFAMIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VINCENZI, B , NAPOLITANO, A , FREZZA, AM , SCHIAVON, G , SANTINI, D , TONINI, G , (2010) WIDE-SPECTRUM CHARACTERIZATION OF TRABECTEDIN: BIOLOGY, CLINICAL ACTIVITY AND FUTURE PERSPECTIVES.PHARMACOGENOMICS. VOL. 11. ISSUE 6. P. 865-878 102 77% 14
2 DEMETRI, GD , VON MEHREN, M , JONES, RL , HENSLEY, ML , SCHUETZE, SM , STADDON, A , MILHEM, M , ELIAS, A , GANJOO, K , TAWBI, H , ET AL (2016) EFFICACY AND SAFETY OF TRABECTEDIN OR DACARBAZINE FOR METASTATIC LIPOSARCOMA OR LEIOMYOSARCOMA AFTER FAILURE OF CONVENTIONAL CHEMOTHERAPY: RESULTS OF A PHASE III RANDOMIZED MULTICENTER CLINICAL TRIAL.JOURNAL OF CLINICAL ONCOLOGY. VOL. 34. ISSUE 8. P. 786 -+ 30 91% 33
3 LARSEN, AK , GALMARINI, CM , D'INCALCI, M , (2016) UNIQUE FEATURES OF TRABECTEDIN MECHANISM OF ACTION.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 77. ISSUE 4. P. 663 -671 50 75% 6
4 SAPONARA, M , STACCHIOTTI, S , GRONCHI, A , (2016) THE SAFETY AND EFFICACY OF TRABECTEDIN FOR THE TREATMENT OF LIPOSARCOMA OR LEIOMYOSARCOMA.EXPERT REVIEW OF ANTICANCER THERAPY. VOL. 16. ISSUE 5. P. 473 -484 57 81% 1
5 DUFFAUD, F , MAKI, RG , JONES, RL , (2016) TREATMENT OF ADVANCED SOFT TISSUE SARCOMA: EFFICACY AND SAFETY OF TRABECTEDIN, A MULTITARGET AGENT, AND UPDATE ON OTHER SYSTEMIC THERAPEUTIC OPTIONS.EXPERT REVIEW OF CLINICAL PHARMACOLOGY. VOL. 9. ISSUE 4. P. 501 -512 55 89% 0
6 D'INCALCI, M , ZAMBELLI, A , (2016) TRABECTEDIN FOR THE TREATMENT OF BREAST CANCER.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 25. ISSUE 1. P. 105 -115 54 81% 1
7 PETEK, BJ , LOGGERS, ET , POLLACK, SM , JONES, RL , (2015) TRABECTEDIN IN SOFT TISSUE SARCOMAS.MARINE DRUGS. VOL. 13. ISSUE 2. P. 974 -983 43 96% 5
8 CESNE, A , DOMONT, J , CIOFFI, A , BONVALOT, S , TERRIER, P , RAY-COQUARD, I , ALFARO, V , LEBEDINSKY, C , SANTABARBARA, P , BLAY, JY , (2009) MAPPING THE LITERATURE: ROLE OF TRABECTEDIN AS A NEW CHEMOTHERAPY OPTION IN ADVANCED PRETREATED SOFT TISSUE SARCOMA.DRUGS OF TODAY. VOL. 45. ISSUE 6. P. 403-421 74 68% 0
9 SHARMA, S , TAKYAR, S , MANSON, SC , POWELL, S , PENEL, N , (2013) EFFICACY AND SAFETY OF PHARMACOLOGICAL INTERVENTIONS IN SECOND- OR LATER-LINE TREATMENT OF PATIENTS WITH ADVANCED SOFT TISSUE SARCOMA: A SYSTEMATIC REVIEW.BMC CANCER. VOL. 13. ISSUE . P. - 53 79% 13
10 LEPORINI, C , PATANE, M , SAULLO, F , RENDE, P , GALLELLI, L , DI PAOLA, ED , TOSCANO, R , LUCIA, M , ROSSI, M , DE SARRO, G , ET AL (2014) A COMPREHENSIVE SAFETY EVALUATION OF TRABECTEDIN AND DRUG-DRUG INTERACTIONS OF TRABECTEDIN-BASED COMBINATIONS.BIODRUGS. VOL. 28. ISSUE 6. P. 499 -511 56 74% 4

Classes with closest relation at Level 1


Rank Class id link
1 19544 RENIERAMYCIN//QUINOCARCIN//SAFRAMYCIN
2 2039 SOFT TISSUE SARCOMA//RETROPERITONEAL SARCOMA//SARCOMA
3 6772 IFOSFAMIDE//MESNA//TROFOSFAMIDE
4 2378 ENDOMETRIAL STROMAL SARCOMA//UTERINE SARCOMA//UTERINE LEIOMYOSARCOMA
5 14510 DOLASTATIN 10//DIDEMNIN B//CRYPTOPHYCIN
6 22812 ALVEOLAR SOFT PART SARCOMA//ALVEOLAR SOFT PART//ALVEOLAR SOFT PART SARCOMA ASPS
7 22418 DESMOPLASTIC SMALL ROUND CELL TUMOR//DSRCT//DESMOPLASTIC SMALL CELL TUMOR
8 8546 SYNOVIAL SARCOMA//SYT SSX//SYT
9 3651 ANGIOSARCOMA//EPITHELIOID ANGIOSARCOMA//CUTANEOUS ANGIOSARCOMA
10 37538 HETEROCYCLIC TRIOXIRANES//TEROXIRONE//HUMAN NON SMALL CELL LUNG CANCER CELLS

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