Class information for:
Level 1: MELPHALAN//CHLORAMBUCIL//PREDNIMUSTINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20094 476 28.7 52%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
2496 2             IFOSFAMIDE//CHEMOSENSITIVITY TEST//MESNA 3914
20094 1                   MELPHALAN//CHLORAMBUCIL//PREDNIMUSTINE 476

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MELPHALAN authKW 261886 11% 8% 54
2 CHLORAMBUCIL authKW 177412 6% 10% 29
3 PREDNIMUSTINE authKW 144328 1% 38% 6
4 LEUKERAN authKW 128298 0% 100% 2
5 MF13 authKW 128298 0% 100% 2
6 NON HAEMATOLOGICAL TOXICITY authKW 128298 0% 100% 2
7 HUMAN MYELOMA CELLS authKW 115466 1% 60% 3
8 CELL CYCLE FLOW authKW 85531 0% 67% 2
9 INT BIOANAL BUSINESS SUPPORT address 85531 0% 67% 2
10 1515 N CAMPBELL AVE address 64149 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 3565 45% 0% 214
2 Pharmacology & Pharmacy 1231 31% 0% 147
3 Chemistry, Analytical 250 11% 0% 53
4 Toxicology 220 7% 0% 34
5 Chemistry, Medicinal 145 6% 0% 28
6 Hematology 123 6% 0% 27
7 Biochemical Research Methods 97 6% 0% 27
8 Chemistry, Multidisciplinary 17 7% 0% 34
9 Genetics & Heredity 9 3% 0% 16
10 Biology 8 2% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INT BIOANAL BUSINESS SUPPORT 85531 0% 67% 2
2 1515 N CAMPBELL AVE 64149 0% 100% 1
3 ANAL BIOELE OCHEM 64149 0% 100% 1
4 CHEM BIOMOL ANALYT MASS SPE OMETRY 64149 0% 100% 1
5 CHEM PL ANALYT ENVIRONM CHEM 64149 0% 100% 1
6 CLIN HAEMATOL STEM CELL TRANSPLANTAT 64149 0% 100% 1
7 COMM CLIN PHARMACOLCANC 64149 0% 100% 1
8 INTERNAL MED HEMATONCOL 64149 0% 100% 1
9 MEDPHD PROGRAM TOXICOL 64149 0% 100% 1
10 MEXICO EU INT ABORAT NETWORK RMAYS 64149 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 21864 11% 1% 50
2 CANCER TREATMENT REPORTS 3506 2% 1% 11
3 CHEMICAL RESEARCH IN TOXICOLOGY 1477 2% 0% 11
4 CANCER RESEARCH 1255 6% 0% 28
5 MUTATION RESEARCH-REVIEWS IN GENETIC TOXICOLOGY 1104 0% 2% 1
6 MEDICAL ONCOLOGY AND TUMOR PHARMACOTHERAPY 790 0% 1% 2
7 BIOCHEMICAL PHARMACOLOGY 660 3% 0% 14
8 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 634 1% 0% 6
9 BLUT 608 1% 0% 3
10 CHEMICO-BIOLOGICAL INTERACTIONS 545 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MELPHALAN 261886 11% 8% 54 Search MELPHALAN Search MELPHALAN
2 CHLORAMBUCIL 177412 6% 10% 29 Search CHLORAMBUCIL Search CHLORAMBUCIL
3 PREDNIMUSTINE 144328 1% 38% 6 Search PREDNIMUSTINE Search PREDNIMUSTINE
4 LEUKERAN 128298 0% 100% 2 Search LEUKERAN Search LEUKERAN
5 MF13 128298 0% 100% 2 Search MF13 Search MF13
6 NON HAEMATOLOGICAL TOXICITY 128298 0% 100% 2 Search NON+HAEMATOLOGICAL+TOXICITY Search NON+HAEMATOLOGICAL+TOXICITY
7 HUMAN MYELOMA CELLS 115466 1% 60% 3 Search HUMAN+MYELOMA+CELLS Search HUMAN+MYELOMA+CELLS
8 CELL CYCLE FLOW 85531 0% 67% 2 Search CELL+CYCLE+FLOW Search CELL+CYCLE+FLOW
9 2 4 2 CHLOROETHYLPIPERAZIN 1 YL 4 6 DIMETHOXY 1 3 5 TRIAZINE 64149 0% 100% 1 Search 2+4+2+CHLOROETHYLPIPERAZIN+1+YL+4+6+DIMETHOXY+1+3+5+TRIAZINE Search 2+4+2+CHLOROETHYLPIPERAZIN+1+YL+4+6+DIMETHOXY+1+3+5+TRIAZINE
10 2 4 6 TRIS4 2 CHLOROETHYLPIPERAZIN 1 YL 1 3 5 TRIAZINE 64149 0% 100% 1 Search 2+4+6+TRIS4+2+CHLOROETHYLPIPERAZIN+1+YL+1+3+5+TRIAZINE Search 2+4+6+TRIS4+2+CHLOROETHYLPIPERAZIN+1+YL+1+3+5+TRIAZINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 NATH, CE , ZENG, L , ESLICK, A , TROTMAN, J , EARL, JW , (2008) AN ISOCRATIC UV HPLC ASSAY FOR ANALYSIS OF TOTAL AND FREE MELPHALAN CONCENTRATIONS IN HUMAN PLASMA.ACTA CHROMATOGRAPHICA. VOL. 20. ISSUE 3. P. 383-398 21 91% 2
2 SINGH, AK , SINGH, M , (2015) QCM SENSING OF MELPHALAN VIA ELECTROPOLYMERIZED MOLECULARLY IMPRINTED POLYTHIOPHENE FILMS.BIOSENSORS & BIOELECTRONICS. VOL. 74. ISSUE . P. 711 -717 18 75% 2
3 NATH, CE , SHAW, PJ , MONTGOMERY, K , EARL, JW , (2005) MELPHALAN PHARMACOKINETICS IN CHILDREN WITH MALIGNANT DISEASE: INFLUENCE OF BODY WEIGHT, RENAL FUNCTION, CARBOPLATIN THERAPY AND TOTAL BODY IRRADIATION.BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. VOL. 59. ISSUE 3. P. 314-324 19 76% 6
4 MOHAMED, D , LINSCHEID, M , (2008) SEPARATION AND IDENTIFICATION OF TRINUCLEOTIDE-MELPHALAN ADDUCTS FROM ENZYMATICALLY DIGESTED DNA USING HPLC-ESI-MS.ANALYTICAL AND BIOANALYTICAL CHEMISTRY. VOL. 392. ISSUE 5. P. 805-817 19 61% 9
5 MOUGENOT, P , PINGUET, F , FABBRO, M , CULINE, S , POUJOL, S , ASTRE, C , BRESSOLLE, F , (2004) POPULATION PHARMACOKINETICS OF MELPHALAN, INFUSED OVER A 24-HOUR PERIOD, IN PATIENTS WITH ADVANCED MALIGNANCIES.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 53. ISSUE 6. P. 503-512 17 74% 8
6 PINGUET, F , MARTEL, P , FABBRO, M , PETIT, I , CANAL, P , CULINE, S , ASTRE, C , BRESSOLLE, F , (1997) PHARMACOKINETICS OF HIGH-DOSE INTRAVENOUS MELPHALAN IN PATIENTS UNDERGOING PERIPHERAL BLOOD HEMATOPOIETIC PROGENITOR-CELL TRANSPLANTATION.ANTICANCER RESEARCH. VOL. 17. ISSUE 1B. P. 605-611 17 89% 23
7 SHAW, PJ , NATH, CE , LAZARUS, HM , (2014) NOT TOO LITTLE, NOT TOO MUCH-JUST RIGHT! (BETTER WAYS TO GIVE HIGH DOSE MELPHALAN).BONE MARROW TRANSPLANTATION. VOL. 49. ISSUE 12. P. 1457 -1465 26 32% 5
8 SPARIDANS, RW , SILVERTAND, L , DOST, F , ROTHBARTH, J , MULDER, GJ , SCHELLENS, JHM , BEIJNEN, JH , (2003) SIMPLE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC ASSAY FOR MELPHALAN IN PERFUSATE, IN RAT LIVER AND TUMOUR TISSUE.BIOMEDICAL CHROMATOGRAPHY. VOL. 17. ISSUE 7. P. 458-464 16 70% 7
9 MOHAMED, D , MOWAKA, S , THOMALE, J , LINSCHEID, MW , (2009) CHLORAMBUCIL-ADDUCTS IN DNA ANALYZED AT THE OLIGONUCLEOTIDE LEVEL USING HPLC-ESI MS.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 22. ISSUE 8. P. 1435-1446 17 53% 19
10 LIND, MJ , ARDIET, C , (1993) PHARMACOKINETICS OF ALKYLATING-AGENTS.CANCER SURVEYS. VOL. 17. ISSUE . P. 157-188 38 38% 44

Classes with closest relation at Level 1


Rank Class id link
1 37538 HETEROCYCLIC TRIOXIRANES//TEROXIRONE//HUMAN NON SMALL CELL LUNG CANCER CELLS
2 27087 HOMO AZA STEROIDAL ESTERS//STEROIDAL ESTERS//HOMO AZA STEROIDS
3 14435 BUTHIONINE SULFOXIMINE//L 2 OXOTHIAZOLIDINE 4 CARBOXYLATE//5 OXO L PROLINASE
4 10003 ISOLATED LIMB PERFUSION//ISOLATED LIMB INFUSION//MELPHALAN
5 26758 BENDAMUSTINE//TREANDA//BENDAMUSTIN
6 31462 CELL MED//H1 CELLS//L15F10 MEDIUM
7 6772 IFOSFAMIDE//MESNA//TROFOSFAMIDE
8 23595 4 THIOTHYMIDINE//ORGAN BIOMIMET CHEM//2 DEOXY 6 THIOGUANOSINE
9 16078 S 2250 KAWAGISHI//TAUROMUSTINE//SARCNU
10 14457 CISPLATIN RESISTANCE//RAT OVARIAN TUMOR CELL LINES//TCRP1

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