Class information for:
Level 1: LAC REPRESSOR//TRP REPRESSOR//LACTOSE REPRESSOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6241 1509 38.5 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
804 2             JOURNAL OF BACTERIOLOGY//PHOSPHOTRANSFERASE SYSTEM//PERIPLASMIC BINDING PROTEIN 12049
6241 1                   LAC REPRESSOR//TRP REPRESSOR//LACTOSE REPRESSOR 1509

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LAC REPRESSOR authKW 475447 3% 50% 47
2 TRP REPRESSOR authKW 459896 2% 78% 29
3 LACTOSE REPRESSOR authKW 222572 1% 100% 11
4 TRP OPERATOR authKW 129493 1% 80% 8
5 DNA LOOPING authKW 121863 2% 22% 27
6 LAMBDA REPRESSOR authKW 111020 1% 37% 15
7 LAC OPERATOR authKW 100457 1% 41% 12
8 INTEGRAT BIOL MODELING address 99141 0% 70% 7
9 LACTOSE REPRESSOR PROTEIN authKW 80935 0% 100% 4
10 GAL REPRESSOR authKW 64747 0% 80% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 14039 77% 0% 1164
2 Biophysics 1698 13% 0% 196
3 Biochemical Research Methods 645 8% 0% 117
4 Cell Biology 511 11% 0% 170
5 Biology 417 5% 0% 81
6 Microbiology 240 7% 0% 101
7 Genetics & Heredity 232 7% 0% 99
8 Mathematical & Computational Biology 45 1% 0% 20
9 Developmental Biology 11 1% 0% 14
10 Chemistry, Analytical 2 2% 0% 32

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTEGRAT BIOL MODELING 99141 0% 70% 7
2 WM KECK INTERDISCIPLINARY BIOSCI TRAINING 60701 0% 100% 3
3 MODELS LIFE 26026 1% 12% 11
4 BIO MET SCI 20234 0% 100% 1
5 BIOL SCI COOKE HALL N CAMPUS 20234 0% 100% 1
6 CHEM CURRICULUM PL MAT SCI 20234 0% 100% 1
7 EQUIPE INTERACT DISTANCE 20234 0% 100% 1
8 ESC SUPER FIS MATEMAT 20234 0% 100% 1
9 GRP BIO SUPRAMOL STRUCT FUNCT 20234 0% 100% 1
10 INSERM U129 UNITE RECH GENET PATHOL MOLEC 20234 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF MOLECULAR BIOLOGY 28407 12% 1% 181
2 BIOCHEMISTRY 8762 10% 0% 153
3 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 4323 2% 1% 26
4 PROTEIN ENGINEERING 2869 1% 1% 18
5 NATURE STRUCTURAL BIOLOGY 2492 1% 1% 14
6 NUCLEIC ACIDS RESEARCH 1941 4% 0% 63
7 EMBO JOURNAL 1832 3% 0% 40
8 PROTEIN SCIENCE 1668 2% 0% 23
9 JOURNAL OF BACTERIOLOGY 1448 3% 0% 50
10 MOLECULAR MICROBIOLOGY 1289 2% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LAC REPRESSOR 475447 3% 50% 47 Search LAC+REPRESSOR Search LAC+REPRESSOR
2 TRP REPRESSOR 459896 2% 78% 29 Search TRP+REPRESSOR Search TRP+REPRESSOR
3 LACTOSE REPRESSOR 222572 1% 100% 11 Search LACTOSE+REPRESSOR Search LACTOSE+REPRESSOR
4 TRP OPERATOR 129493 1% 80% 8 Search TRP+OPERATOR Search TRP+OPERATOR
5 DNA LOOPING 121863 2% 22% 27 Search DNA+LOOPING Search DNA+LOOPING
6 LAMBDA REPRESSOR 111020 1% 37% 15 Search LAMBDA+REPRESSOR Search LAMBDA+REPRESSOR
7 LAC OPERATOR 100457 1% 41% 12 Search LAC+OPERATOR Search LAC+OPERATOR
8 LACTOSE REPRESSOR PROTEIN 80935 0% 100% 4 Search LACTOSE+REPRESSOR+PROTEIN Search LACTOSE+REPRESSOR+PROTEIN
9 GAL REPRESSOR 64747 0% 80% 4 Search GAL+REPRESSOR Search GAL+REPRESSOR
10 LAC HEADPIECE 60701 0% 100% 3 Search LAC+HEADPIECE Search LAC+HEADPIECE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MATTHEWS, KS , NICHOLS, JC , (1998) LACTOSE REPRESSOR PROTEIN: FUNCTIONAL PROPERTIES AND STRUCTURE.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 58. VOL. 58. ISSUE . P. 127 -164 118 78% 42
2 WILSON, CJ , ZHAN, H , SWINT-KRUSE, L , MATTHEWS, KS , (2007) THE LACTOSE REPRESSOR SYSTEM: PARADIGMS FOR REGULATION, ALLOSTERIC BEHAVIOR AND PROTEIN FOLDING.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 64. ISSUE 1. P. 3-16 68 70% 73
3 TABAKA, M , CYBULSKI, O , HOLYST, R , (2008) ACCURATE GENETIC SWITCH IN ESCHERICHIA COLI: NOVEL MECHANISM OF REGULATION BY CO-REPRESSOR.JOURNAL OF MOLECULAR BIOLOGY. VOL. 377. ISSUE 4. P. 1002 -1014 52 85% 6
4 TARABAN, M , ZHAN, H , WHITTEN, AE , LANGLEY, DB , MATTHEWS, KS , SWINT-KRUSE, L , TREWHELLA, J , (2008) LIGAND-INDUCED CONFORMATIONAL CHANGES AND CONFORMATIONAL DYNAMICS IN THE SOLUTION STRUCTURE OF THE LACTOSE REPRESSOR PROTEIN.JOURNAL OF MOLECULAR BIOLOGY. VOL. 376. ISSUE 2. P. 466-481 46 78% 21
5 SWINT-KRUSE, L , ZHAN, HL , MATTHEWS, KS , (2005) INTEGRATED INSIGHTS FROM SIMULATION, EXPERIMENT, AND MUTATIONAL ANALYSIS YIELD NEW DETAILS OF LACI FUNCTION.BIOCHEMISTRY. VOL. 44. ISSUE 33. P. 11201-11213 41 95% 22
6 SWINT-KRUSE, L , MATTHEWS, KS , (2009) ALLOSTERY IN THE LACL/GAIR FAMILY: VARIATIONS ON A THEME.CURRENT OPINION IN MICROBIOLOGY. VOL. 12. ISSUE 2. P. 129 -137 44 67% 47
7 FALCON, CM , MATTHEWS, KS , (2000) OPERATOR DNA SEQUENCE VARIATION ENHANCES HIGH AFFINITY BINDING BY HINGE HELIX MUTANTS OF LACTOSE REPRESSOR PROTEIN.BIOCHEMISTRY. VOL. 39. ISSUE 36. P. 11074 -11083 59 67% 37
8 SWINT-KRUSE, L , LARSON, C , PETTITT, BM , MATTHEWS, KS , (2002) FINE-TUNING FUNCTION: CORRELATION OF HINGE DOMAIN INTERACTIONS WITH FUNCTIONAL DISTINCTIONS BETWEEN LACI AND PURR.PROTEIN SCIENCE. VOL. 11. ISSUE 4. P. 778-794 48 79% 21
9 SWINT-KRUSE, L , (2004) USING NETWORKS TO IDENTIFY FINE STRUCTURAL DIFFERENCES BETWEEN FUNCTIONALLY DISTINCT PROTEIN STATES.BIOCHEMISTRY. VOL. 43. ISSUE 34. P. 10886-10895 42 82% 22
10 MEINHARDT, S , MANLEY, MW , BECKER, NA , HESSMAN, JA , MAHER, LJ , SWINT-KRUSE, L , (2012) NOVEL INSIGHTS FROM HYBRID LACI/GALR PROTEINS: FAMILY-WIDE FUNCTIONAL ATTRIBUTES AND BIOLOGICALLY SIGNIFICANT VARIATION IN TRANSCRIPTION REPRESSION.NUCLEIC ACIDS RESEARCH. VOL. 40. ISSUE 21. P. 11139-11154 45 56% 10

Classes with closest relation at Level 1


Rank Class id link
1 18765 CYCLIC AMP RECEPTOR PROTEIN//CATABOLITE ACTIVATOR PROTEIN CAP//CAMP RECEPTOR PROTEIN
2 27495 UM SYLVESTER BRAMAN FAMILY BREAST CANC//GCN4P//DNA PROMOTER ELEMENTS TRE AND CRE
3 24120 ARAC PROTEIN//ARAC//ARAC XYLS FAMILY
4 19752 NARROW ESCAPE//NONSPECIFIC PROTEIN DNA INTERACTIONS//TARGET SEARCH PROCESS
5 5558 RNA POLYMERASE//ESCHERICHIA COLI RNA POLYMERASE//SIGMA70
6 34853 TRIVALINE//TRIPLE RINGS//4 4 SULFONYLDIANILINE
7 20819 TET REPRESSOR//TETRACYCLINE H ANTIPORTER//TETRACYCLINE RESISTANCE PROTEIN
8 32849 TRANSCRIPTION FACTOR DETECTION//MOL IMAGING PROBES//CELL NUCLEAR EXTRACTS
9 18221 SKIRBALL PROGRAM MOL PATHOGENESIS//RETRON//MSDNA
10 16509 TYRR//LONG ACCURATE PCR//BACILLUS SUBTILIS GENOME SEQUENCING

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