Class information for:
Level 1: DRUG INDUCED LIVER INJURY//HEPATOTOXICITY//HERB INDUCED LIVER INJURY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5104 1672 38.6 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
547 3       ACETAMINOPHEN//CARBON MONOXIDE POISONING//POISONING 18371
1613 2             ACETAMINOPHEN//DRUG INDUCED LIVER INJURY//HEPATOTOXICITY 7077
5104 1                   DRUG INDUCED LIVER INJURY//HEPATOTOXICITY//HERB INDUCED LIVER INJURY 1672

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG INDUCED LIVER INJURY authKW 1543435 12% 41% 206
2 HEPATOTOXICITY authKW 396046 17% 8% 284
3 HERB INDUCED LIVER INJURY authKW 332016 1% 91% 20
4 DILI authKW 277723 2% 45% 34
5 CAUSALITY ASSESSMENT authKW 247671 2% 47% 29
6 HERBAL HEPATOTOXICITY authKW 204006 1% 62% 18
7 HYS LAW authKW 169965 1% 85% 11
8 DRUG INDUCED HEPATITIS authKW 163964 2% 29% 31
9 IDIOSYNCRATIC HEPATOTOXICITY authKW 130430 1% 71% 10
10 IND ENVIRONM SOCIAL MED address 129855 0% 89% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Gastroenterology & Hepatology 27521 39% 0% 649
2 Pharmacology & Pharmacy 3182 27% 0% 450
3 Toxicology 1612 10% 0% 166
4 Medicine, General & Internal 1373 15% 0% 243
5 Integrative & Complementary Medicine 382 2% 0% 33
6 Medicine, Legal 138 1% 0% 18
7 Public, Environmental & Occupational Health 78 4% 0% 71
8 Chemistry, Medicinal 56 3% 0% 42
9 Psychiatry 29 3% 0% 45
10 Transplantation 9 1% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IND ENVIRONM SOCIAL MED 129855 0% 89% 8
2 KLINIKUM HANAU 125208 1% 57% 12
3 HOSP UNIV VIRGEN VICTORIA 82994 1% 45% 10
4 CLIN SAFETY SYST 54783 0% 100% 3
5 FARMACOLCOORDINATING 54783 0% 100% 3
6 GRP ESTUDIO HEPATOPATIAS ASOCIADAS MEDICAMENTOS 54783 0% 100% 3
7 KLINIKUM HANAU GASTROENTEROL HEPATOL 54783 0% 100% 3
8 HOSP UNIV VIRGEN DE LA VICTORIA 54771 1% 33% 9
9 UNIDAD HEPATOL 47397 1% 13% 20
10 DIAG TREATMENT NONINFECT DIS 41086 0% 75% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 12914 3% 1% 56
2 SEMINARS IN LIVER DISEASE 12188 2% 2% 30
3 CLINICS IN LIVER DISEASE 11490 1% 4% 17
4 DRUG SAFETY 8914 2% 2% 32
5 JOURNAL OF HEPATOLOGY 6446 3% 1% 52
6 ANNALS OF HEPATOLOGY 5493 1% 2% 15
7 PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 5302 2% 1% 26
8 EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY 4717 1% 1% 18
9 EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY 3993 2% 1% 35
10 ANNALS OF PHARMACOTHERAPY 3875 2% 1% 34

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DRUG INDUCED LIVER INJURY 1543435 12% 41% 206 Search DRUG+INDUCED+LIVER+INJURY Search DRUG+INDUCED+LIVER+INJURY
2 HEPATOTOXICITY 396046 17% 8% 284 Search HEPATOTOXICITY Search HEPATOTOXICITY
3 HERB INDUCED LIVER INJURY 332016 1% 91% 20 Search HERB+INDUCED+LIVER+INJURY Search HERB+INDUCED+LIVER+INJURY
4 DILI 277723 2% 45% 34 Search DILI Search DILI
5 CAUSALITY ASSESSMENT 247671 2% 47% 29 Search CAUSALITY+ASSESSMENT Search CAUSALITY+ASSESSMENT
6 HERBAL HEPATOTOXICITY 204006 1% 62% 18 Search HERBAL+HEPATOTOXICITY Search HERBAL+HEPATOTOXICITY
7 HYS LAW 169965 1% 85% 11 Search HYS+LAW Search HYS+LAW
8 DRUG INDUCED HEPATITIS 163964 2% 29% 31 Search DRUG+INDUCED+HEPATITIS Search DRUG+INDUCED+HEPATITIS
9 IDIOSYNCRATIC HEPATOTOXICITY 130430 1% 71% 10 Search IDIOSYNCRATIC+HEPATOTOXICITY Search IDIOSYNCRATIC+HEPATOTOXICITY
10 DRUG INDUCED LIVER DISEASE 114001 1% 39% 16 Search DRUG+INDUCED+LIVER+DISEASE Search DRUG+INDUCED+LIVER+DISEASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DANAN, G , TESCHKE, R , (2016) RUCAM IN DRUG AND HERB INDUCED LIVER INJURY: THE UPDATE.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 17. ISSUE 1. P. - 85 79% 7
2 LEWIS, JH , (2015) THE ART AND SCIENCE OF DIAGNOSING AND MANAGING DRUG-INDUCED LIVER INJURY IN 2015 AND BEYOND.CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. VOL. 13. ISSUE 12. P. 2173 -+ 112 62% 9
3 TESCHKE, R , EICKHOFF, A , (2015) HERBAL HEPATOTOXICITY IN TRADITIONAL AND MODERN MEDICINE: ACTUAL KEY ISSUES AND NEW ENCOURAGING STEPS.FRONTIERS IN PHARMACOLOGY. VOL. 6. ISSUE . P. - 110 64% 6
4 FRENZEL, C , TESCHKE, R , (2016) HERBAL HEPATOTOXICITY: CLINICAL CHARACTERISTICS AND LISTING COMPILATION.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 17. ISSUE 5. P. - 100 59% 4
5 BUNCHORNTAVAKUL, C , REDDY, KR , (2013) REVIEW ARTICLE: HERBAL AND DIETARY SUPPLEMENT HEPATOTOXICITY.ALIMENTARY PHARMACOLOGY & THERAPEUTICS. VOL. 37. ISSUE 1. P. 3-17 70 54% 81
6 SERRANTI, D , MONTAGNANI, C , INDOLFI, G , CHIAPPINI, E , GALLI, L , DE MARTINO, M , (2013) ANTIBIOTIC INDUCED LIVER INJURY: WHAT ABOUT CHILDREN?.JOURNAL OF CHEMOTHERAPY. VOL. 25. ISSUE 5. P. 255-272 77 69% 2
7 TESCHKE, R , FRENZEL, C , SCHULZE, J , EICKHOFF, A , (2013) HERBAL HEPATOTOXICITY: CHALLENGES AND PITFALLS OF CAUSALITY ASSESSMENT METHODS.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 19. ISSUE 19. P. 2864 -2882 57 79% 19
8 TESCHKE, R , WOLFF, A , FRENZEL, C , SCHULZE, J , EICKHOFF, A , (2012) HERBAL HEPATOTOXICITY: A TABULAR COMPILATION OF REPORTED CASES.LIVER INTERNATIONAL. VOL. 32. ISSUE 10. P. 1543 -1556 67 64% 35
9 VOICAN, CS , CORRUBLE, E , NAVEAU, S , PERLEMUTER, G , (2014) ANTIDEPRESSANT-INDUCED LIVER INJURY: A REVIEW FOR CLINICIANS.AMERICAN JOURNAL OF PSYCHIATRY. VOL. 171. ISSUE 4. P. 404-415 57 60% 41
10 SCHWARZENBOECK, A , EICKHOFF, A , FRENZEL, C , WOLFF, A , SCHULZE, J , TESCHKE, R , (2013) CLINICAL AND CAUSALITY ASSESSMENT IN HERBAL HEPATOTOXICITY.EXPERT OPINION ON DRUG SAFETY. VOL. 12. ISSUE 3. P. 339 -366 52 78% 11

Classes with closest relation at Level 1


Rank Class id link
1 16470 ISONIAZID//ANTITUBERCULOSIS DRUG INDUCED HEPATOTOXICITY//DRUG REASSESSMENT
2 25846 IDIOSYNCRATIC DRUG INDUCED LIVER INJURY//PHAGOCYTOSIS BLOCKADE//ALPHA NAPHTHYLISOTHIOCYANATE
3 14478 ACYL GLUCURONIDE//ZOMEPIRAC//DRUG PROTEIN ADDUCTS
4 21628 KAVA//PIPER METHYSTICUM//KAVALACTONES
5 27145 NITROFURANTOIN//DOSE ADMINISTRATION AIDS//MONITORED DOSAGE SYSTEM
6 28818 HEPARG CELLS//HEPARG//NEOHEPATOCYTES
7 31820 ALVERINE//THERAPIE//ASSOC FRANCAISE REGIONAUX PHARMACOVIGILANCE
8 29519 EXTRACELLULAR FLUX//COMPOUND SAFETY PREDICT//UAB MITOCHONDRIAL MED
9 35955 GIANT CELL HEPATITIS//SYNCYTIAL GIANT CELL HEPATITIS//POSTINFANTILE GIANT CELL HEPATITIS
10 12378 DRESS SYNDROME//DRUG INDUCED HYPERSENSITIVITY SYNDROME//HYPERSENSITIVITY SYNDROME

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