Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
28818 | 199 | 45.4 | 88% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
537 | 3 | BIOARTIFICIAL LIVER//HEPATOCYTES//HEPATOCYTE TRANSPLANTATION | 19236 |
908 | 2 | BIOARTIFICIAL LIVER//HEPATOCYTES//HEPATOCYTE TRANSPLANTATION | 11255 |
28818 | 1 | HEPARG CELLS//HEPARG//NEOHEPATOCYTES | 199 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | HEPARG CELLS | authKW | 958072 | 8% | 39% | 16 |
2 | HEPARG | authKW | 903903 | 9% | 33% | 18 |
3 | NEOHEPATOCYTES | authKW | 460333 | 2% | 100% | 3 |
4 | IDMOC | authKW | 345248 | 2% | 75% | 3 |
5 | CYP ENGINEERED CELL LINE | authKW | 306889 | 1% | 100% | 2 |
6 | HEPG2 TRANSFORMANTS | authKW | 306889 | 1% | 100% | 2 |
7 | NONCLIN DEV EARLY EXPLANATORY TOXICOL | address | 306889 | 1% | 100% | 2 |
8 | PRIMARY HUMAN HEPATOCYTES | authKW | 214278 | 5% | 16% | 9 |
9 | PROGRAMMABLE CELLS OF MONOCYTIC ORIGIN | authKW | 204591 | 1% | 67% | 2 |
10 | MERCK SERONO | address | 187110 | 5% | 12% | 10 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Toxicology | 5455 | 49% | 0% | 98 |
2 | Pharmacology & Pharmacy | 892 | 40% | 0% | 79 |
3 | Integrative & Complementary Medicine | 47 | 2% | 0% | 4 |
4 | Cell & Tissue Engineering | 47 | 2% | 0% | 3 |
5 | Gastroenterology & Hepatology | 16 | 4% | 0% | 7 |
6 | Medicine, Research & Experimental | 16 | 5% | 0% | 9 |
7 | Biochemistry & Molecular Biology | 15 | 12% | 0% | 24 |
8 | Pathology | 13 | 3% | 0% | 6 |
9 | Cell Biology | 11 | 6% | 0% | 12 |
10 | Transplantation | 6 | 2% | 0% | 3 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | NONCLIN DEV EARLY EXPLANATORY TOXICOL | 306889 | 1% | 100% | 2 |
2 | MERCK SERONO | 187110 | 5% | 12% | 10 |
3 | AIMMS IS MOL TOXICOL | 153444 | 1% | 100% | 1 |
4 | BG CLIN | 153444 | 1% | 100% | 1 |
5 | BIOSTAT MED BIOSTAT C060 | 153444 | 1% | 100% | 1 |
6 | BVT | 153444 | 1% | 100% | 1 |
7 | CN BIO | 153444 | 1% | 100% | 1 |
8 | DR EDUARDO LICEAGA MED | 153444 | 1% | 100% | 1 |
9 | EA MDC U522 | 153444 | 1% | 100% | 1 |
10 | EA MDC U620 | 153444 | 1% | 100% | 1 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | TOXICOLOGY IN VITRO | 27850 | 14% | 1% | 28 |
2 | DRUG METABOLISM AND DISPOSITION | 9017 | 11% | 0% | 21 |
3 | ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN | 7432 | 2% | 1% | 4 |
4 | EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY | 4425 | 3% | 0% | 6 |
5 | VITAE-REVISTA DE LA FACULTAD DE QUIMICA FARMACEUTICA | 3425 | 1% | 1% | 2 |
6 | CHEMICO-BIOLOGICAL INTERACTIONS | 3276 | 6% | 0% | 11 |
7 | TOXICOLOGICAL SCIENCES | 3137 | 5% | 0% | 10 |
8 | CELL BIOLOGY AND TOXICOLOGY | 2092 | 2% | 0% | 4 |
9 | TOXICOLOGY AND APPLIED PHARMACOLOGY | 990 | 4% | 0% | 8 |
10 | XENOBIOTICA | 984 | 3% | 0% | 5 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | HEPARG CELLS | 958072 | 8% | 39% | 16 | Search HEPARG+CELLS | Search HEPARG+CELLS |
2 | HEPARG | 903903 | 9% | 33% | 18 | Search HEPARG | Search HEPARG |
3 | NEOHEPATOCYTES | 460333 | 2% | 100% | 3 | Search NEOHEPATOCYTES | Search NEOHEPATOCYTES |
4 | IDMOC | 345248 | 2% | 75% | 3 | Search IDMOC | Search IDMOC |
5 | CYP ENGINEERED CELL LINE | 306889 | 1% | 100% | 2 | Search CYP+ENGINEERED+CELL+LINE | Search CYP+ENGINEERED+CELL+LINE |
6 | HEPG2 TRANSFORMANTS | 306889 | 1% | 100% | 2 | Search HEPG2+TRANSFORMANTS | Search HEPG2+TRANSFORMANTS |
7 | PRIMARY HUMAN HEPATOCYTES | 214278 | 5% | 16% | 9 | Search PRIMARY+HUMAN+HEPATOCYTES | Search PRIMARY+HUMAN+HEPATOCYTES |
8 | PROGRAMMABLE CELLS OF MONOCYTIC ORIGIN | 204591 | 1% | 67% | 2 | Search PROGRAMMABLE+CELLS+OF+MONOCYTIC+ORIGIN | Search PROGRAMMABLE+CELLS+OF+MONOCYTIC+ORIGIN |
9 | 1 AMINOBENZOTRIZOLE | 153444 | 1% | 100% | 1 | Search 1+AMINOBENZOTRIZOLE | Search 1+AMINOBENZOTRIZOLE |
10 | 3D MICRO SCAFFOLD | 153444 | 1% | 100% | 1 | Search 3D+MICRO+SCAFFOLD | Search 3D+MICRO+SCAFFOLD |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | JETTEN, MJA , KLEINJANS, JCS , CLAESSEN, SM , CHESNE, C , VAN DELFT, JHM , (2013) BASELINE AND GENOTOXIC COMPOUND INDUCED GENE EXPRESSION PROFILES IN HEPG2 AND HEPARG COMPARED TO PRIMARY HUMAN HEPATOCYTES.TOXICOLOGY IN VITRO. VOL. 27. ISSUE 7. P. 2031-2040 | 21 | 40% | 15 |
2 | HERZOG, N , HANSEN, M , MIETHBAUER, S , SCHMIDTKE, KU , ANDERER, U , LUPP, A , SPERLING, S , SEEHOFER, D , DAMM, G , SCHEIBNER, K , ET AL (2016) PRIMARY-LIKE HUMAN HEPATOCYTES GENETICALLY ENGINEERED TO OBTAIN PROLIFERATION COMPETENCE DISPLAY HEPATIC DIFFERENTIATION CHARACTERISTICS IN MONOLAYER AND ORGANOTYPICAL SPHEROID CULTURES.CELL BIOLOGY INTERNATIONAL. VOL. 40. ISSUE 3. P. 341 -353 | 19 | 40% | 0 |
3 | HUANG, LZ , ZOU, SX , DENG, JF , DAI, TM , JIANG, JW , JIA, Y , DAI, RK , XIE, SL , (2016) DEVELOPMENT OF AN OPTIMIZED CYTOTOXICITY ASSAY SYSTEM FOR CYP3A4-MEDIATED METABOLIC ACTIVATION VIA MODIFIED PIGGYBAC TRANSPOSITION.TOXICOLOGY IN VITRO. VOL. 32. ISSUE . P. 132 -137 | 12 | 55% | 1 |
4 | ANDERSSON, TB , KANEBRATT, KP , KENNA, JG , (2012) THE HEPARG CELL LINE: A UNIQUE IN VITRO TOOL FOR UNDERSTANDING DRUG METABOLISM AND TOXICOLOGY IN HUMAN.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 8. ISSUE 7. P. 909 -920 | 17 | 39% | 39 |
5 | ANTHERIEU, S , CHESNE, C , LI, RY , GUGUEN-GUILLOUZO, C , GUILLOUZO, A , (2012) OPTIMIZATION OF THE HEPARG CELL MODEL FOR DRUG METABOLISM AND TOXICITY STUDIES.TOXICOLOGY IN VITRO. VOL. 26. ISSUE 8. P. 1278-1285 | 19 | 35% | 33 |
6 | SAVARY, CC , JIANG, XQ , AUBRY, M , JOSSE, R , KOPP-SCHNEIDER, A , HEWITT, P , GUILLOUZO, A , (2015) TRANSCRIPTOMIC ANALYSIS OF UNTREATED AND DRUG-TREATED DIFFERENTIATED HEPARG CELLS OVER A 2-WEEK PERIOD.TOXICOLOGY IN VITRO. VOL. 30. ISSUE 1. P. 27 -35 | 13 | 46% | 2 |
7 | FERREIRA, A , RODRIGUES, M , SILVESTRE, S , FALCAO, A , ALVES, G , (2014) HEPARG CELL LINE AS AN IN VITRO MODEL FOR SCREENING DRUG-DRUG INTERACTIONS MEDIATED BY METABOLIC INDUCTION: AMIODARONE USED AS A MODEL SUBSTANCE.TOXICOLOGY IN VITRO. VOL. 28. ISSUE 8. P. 1531 -1535 | 15 | 38% | 0 |
8 | ROGUE, A , LAMBERT, C , SPIRE, C , CLAUDE, N , GUILLOUZO, A , (2012) INTERINDIVIDUAL VARIABILITY IN GENE EXPRESSION PROFILES IN HUMAN HEPATOCYTES AND COMPARISON WITH HEPARG CELLS.DRUG METABOLISM AND DISPOSITION. VOL. 40. ISSUE 1. P. 151-158 | 12 | 46% | 12 |
9 | GOMEZ-LECHON, MJ , TOLOSA, L , CONDE, I , DONATO, MT , (2014) COMPETENCY OF DIFFERENT CELL MODELS TO PREDICT HUMAN HEPATOTOXIC DRUGS.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 10. ISSUE 11. P. 1553 -1568 | 24 | 21% | 14 |
10 | GERETS, HHJ , TILMANT, K , GERIN, B , CHANTEUX, H , DEPELCHIN, BO , DHALLUIN, S , ATIENZAR, FA , (2012) CHARACTERIZATION OF PRIMARY HUMAN HEPATOCYTES, HEPG2 CELLS, AND HEPARG CELLS AT THE MRNA LEVEL AND CYP ACTIVITY IN RESPONSE TO INDUCERS AND THEIR PREDICTIVITY FOR THE DETECTION OF HUMAN HEPATOTOXINS.CELL BIOLOGY AND TOXICOLOGY. VOL. 28. ISSUE 2. P. 69-87 | 12 | 30% | 111 |
Classes with closest relation at Level 1 |