Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
14478 | 767 | 33.5 | 64% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
275 | 3 | NSAIDS//CYCLOOXYGENASE//CYCLOOXYGENASE 2 | 43399 |
466 | 2 | NSAIDS//NON STEROIDAL ANTI INFLAMMATORY DRUGS//COX 2 INHIBITORS | 15930 |
14478 | 1 | ACYL GLUCURONIDE//ZOMEPIRAC//DRUG PROTEIN ADDUCTS | 767 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | ACYL GLUCURONIDE | authKW | 935893 | 6% | 49% | 48 |
2 | ZOMEPIRAC | authKW | 331747 | 1% | 83% | 10 |
3 | DRUG PROTEIN ADDUCTS | authKW | 159232 | 1% | 50% | 8 |
4 | FENCLOZIC ACID | authKW | 119430 | 0% | 100% | 3 |
5 | GLUCURONATES | authKW | 119424 | 1% | 50% | 6 |
6 | ROMAZARIT | authKW | 89571 | 0% | 75% | 3 |
7 | ACYL MIGRATION REACTIONS | authKW | 79620 | 0% | 100% | 2 |
8 | ASTRAZENECA UK LTD | address | 79620 | 0% | 100% | 2 |
9 | CAS 26171 23 3 | authKW | 79620 | 0% | 100% | 2 |
10 | DICLOFENAC METABOLISM | authKW | 79620 | 0% | 100% | 2 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Pharmacology & Pharmacy | 6532 | 54% | 0% | 411 |
2 | Toxicology | 2251 | 17% | 0% | 128 |
3 | Chemistry, Medicinal | 819 | 10% | 0% | 79 |
4 | Chemistry, Analytical | 345 | 10% | 0% | 80 |
5 | Gastroenterology & Hepatology | 219 | 6% | 0% | 45 |
6 | Medicine, General & Internal | 191 | 9% | 0% | 68 |
7 | Rheumatology | 138 | 3% | 0% | 21 |
8 | Chemistry, Multidisciplinary | 90 | 10% | 0% | 77 |
9 | Biochemical Research Methods | 83 | 4% | 0% | 34 |
10 | Medicine, Research & Experimental | 8 | 2% | 0% | 19 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | ASTRAZENECA UK LTD | 79620 | 0% | 100% | 2 |
2 | PHARMACEUT SCI HLTH MED SCI | 79620 | 0% | 100% | 2 |
3 | ROBERT ROBINSON S | 68349 | 2% | 11% | 15 |
4 | STUDIES DRUG DISPOSIT | 43264 | 1% | 22% | 5 |
5 | ALLERGY UNITAMBULATORIO ALLERGOL | 39810 | 0% | 100% | 1 |
6 | AZM TRIPOLI | 39810 | 0% | 100% | 1 |
7 | BIOANAL METAB | 39810 | 0% | 100% | 1 |
8 | BOX EHSC | 39810 | 0% | 100% | 1 |
9 | BUNDESWEHRZENT KRANKENHAUS KOBLENZ | 39810 | 0% | 100% | 1 |
10 | CENT CHEM BIOCHEM PHARMACOL | 39810 | 0% | 100% | 1 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | DRUG METABOLISM AND DISPOSITION | 48926 | 13% | 1% | 96 |
2 | CHEMICAL RESEARCH IN TOXICOLOGY | 14125 | 6% | 1% | 43 |
3 | XENOBIOTICA | 8030 | 4% | 1% | 28 |
4 | PROGRESS IN DRUG METABOLISM | 3617 | 0% | 9% | 1 |
5 | DRUG METABOLISM REVIEWS | 2547 | 1% | 1% | 8 |
6 | BIOPHARMACEUTICS & DRUG DISPOSITION | 2050 | 1% | 1% | 10 |
7 | BIOCHEMICAL PHARMACOLOGY | 2030 | 4% | 0% | 31 |
8 | CURRENT DRUG METABOLISM | 1769 | 1% | 1% | 7 |
9 | ANNALES DE GASTROENTEROLOGIE ET D HEPATOLOGIE | 1739 | 1% | 1% | 5 |
10 | EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS | 1257 | 1% | 0% | 7 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | ACYL GLUCURONIDE | 935893 | 6% | 49% | 48 | Search ACYL+GLUCURONIDE | Search ACYL+GLUCURONIDE |
2 | ZOMEPIRAC | 331747 | 1% | 83% | 10 | Search ZOMEPIRAC | Search ZOMEPIRAC |
3 | DRUG PROTEIN ADDUCTS | 159232 | 1% | 50% | 8 | Search DRUG+PROTEIN+ADDUCTS | Search DRUG+PROTEIN+ADDUCTS |
4 | FENCLOZIC ACID | 119430 | 0% | 100% | 3 | Search FENCLOZIC+ACID | Search FENCLOZIC+ACID |
5 | GLUCURONATES | 119424 | 1% | 50% | 6 | Search GLUCURONATES | Search GLUCURONATES |
6 | ROMAZARIT | 89571 | 0% | 75% | 3 | Search ROMAZARIT | Search ROMAZARIT |
7 | ACYL MIGRATION REACTIONS | 79620 | 0% | 100% | 2 | Search ACYL+MIGRATION+REACTIONS | Search ACYL+MIGRATION+REACTIONS |
8 | CAS 26171 23 3 | 79620 | 0% | 100% | 2 | Search CAS+26171+23+3 | Search CAS+26171+23+3 |
9 | DICLOFENAC METABOLISM | 79620 | 0% | 100% | 2 | Search DICLOFENAC+METABOLISM | Search DICLOFENAC+METABOLISM |
10 | CLEARANCE RENAL | 71656 | 0% | 60% | 3 | Search CLEARANCE+RENAL | Search CLEARANCE+RENAL |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | DICKINSON, RG , (2011) ISO-GLUCURONIDES.CURRENT DRUG METABOLISM. VOL. 12. ISSUE 3. P. 222-228 | 50 | 94% | 5 |
2 | SHIPKOVA, M , ARMSTRONG, VW , OELLERICH, M , WIELAND, E , (2003) ACYL GLUCURONIDE DRUG METABOLITES: TOXICOLOGICAL AND ANALYTICAL IMPLICATIONS.THERAPEUTIC DRUG MONITORING. VOL. 25. ISSUE 1. P. 1-16 | 81 | 56% | 156 |
3 | SKONBERG, C , OLSEN, J , MADSEN, KG , HANSEN, SH , GRILLO, MP , (2008) METABOLIC ACTIVATION OF CARBOXYLIC ACIDS.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 4. ISSUE 4. P. 425-438 | 61 | 64% | 55 |
4 | BABA, A , YOSHIOKA, T , (2009) STRUCTURE-ACTIVITY RELATIONSHIPS FOR DEGRADATION REACTION OF 1-BETA-O-ACYL GLUCURONIDES: KINETIC DESCRIPTION AND PREDICTION OF INTRINSIC ELECTROPHILIC REACTIVITY UNDER PHYSIOLOGICAL CONDITIONS.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 22. ISSUE 1. P. 158-172 | 60 | 67% | 15 |
5 | STACHULSKI, AV , HARDING, JR , LINDON, JC , MAGGS, JL , PARK, BK , WILSON, ID , (2006) ACYL GLUCURONIDES: BIOLOGICAL ACTIVITY, CHEMICAL REACTIVITY, AND CHEMICAL SYNTHESIS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 49. ISSUE 24. P. 6931-6945 | 75 | 53% | 50 |
6 | REGAN, SL , MAGGS, JL , HAMMOND, TG , LAMBERT, C , WILLIAMS, DP , PARK, BK , (2010) ACYL GLUCURONIDES: THE GOOD, THE BAD AND THE UGLY.BIOPHARMACEUTICS & DRUG DISPOSITION. VOL. 31. ISSUE 7. P. 367-395 | 74 | 43% | 55 |
7 | BOELSTERLI, UA , (2003) DICLOFENAC-INDUCED LIVER INJURY: A PARADIGM OF IDIOSYNCRATIC DRUG TOXICITY.TOXICOLOGY AND APPLIED PHARMACOLOGY. VOL. 192. ISSUE 3. P. 307-322 | 55 | 60% | 195 |
8 | YANG, XX , HU, ZP , BOELSTERLI, UA , ZHOU, SF , (2006) DRUG ACYL GLUCURONIDES: REACTIVITY AND ANALYTICAL IMPLICATION.CURRENT PHARMACEUTICAL ANALYSIS. VOL. 2. ISSUE 3. P. 259 -277 | 81 | 46% | 10 |
9 | SYED, M , SKONBERG, C , HANSEN, SH , (2016) MITOCHONDRIAL TOXICITY OF DICLOFENAC AND ITS METABOLITES VIA INHIBITION OF OXIDATIVE PHOSPHORYLATION (ATP SYNTHESIS) IN RAT LIVER MITOCHONDRIA: POSSIBLE ROLE IN DRUG INDUCED LIVER INJURY (DILI).TOXICOLOGY IN VITRO. VOL. 31. ISSUE . P. 93 -102 | 32 | 68% | 4 |
10 | JOHNSON, CH , WILSON, ID , HARDING, JR , STACHULSKI, AV , IDDON, L , NICHOLSON, JK , LINDON, JC , (2007) NMR SPECTROSCOPIC STUDIES ON THE IN VITRO ACYL GLUCURONIDE MIGRATION KINETICS OF LBUPROFEN ((+/-)-(R,S)-2-(4-ISOBUTYLPHENYL) PROPANOIC ACID), ITS METABOLITES, AND ANALOGUES.ANALYTICAL CHEMISTRY. VOL. 79. ISSUE 22. P. 8720-8727 | 41 | 77% | 17 |
Classes with closest relation at Level 1 |