Class information for:
Level 1: EFFLUX PUMP INHIBITOR//EFFLUX PUMPS//EMRE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3970 1872 44.7 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
73 3       MICROBIOLOGY//INFECTIOUS DISEASES//STAPHYLOCOCCUS AUREUS 82747
233 2             ACINETOBACTER BAUMANNII//EXTENDED SPECTRUM BETA LACTAMASE//ESBL 20247
3970 1                   EFFLUX PUMP INHIBITOR//EFFLUX PUMPS//EMRE 1872

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EFFLUX PUMP INHIBITOR authKW 708721 4% 61% 71
2 EFFLUX PUMPS authKW 514034 7% 23% 138
3 EMRE authKW 334534 2% 71% 29
4 MULTIDRUG EFFLUX PUMP authKW 301696 2% 50% 37
5 MULTIDRUG EFFLUX authKW 283074 1% 64% 27
6 ACRB authKW 268237 1% 66% 25
7 CELL MEMBRANE BIOL address 260902 2% 36% 44
8 TOLC authKW 250699 1% 55% 28
9 AD TAT GENET DRUG ISTANCE address 219194 2% 40% 34
10 RND TRANSPORTERS authKW 193137 1% 79% 15

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Microbiology 27191 50% 0% 938
2 Biochemistry & Molecular Biology 3036 35% 0% 663
3 Pharmacology & Pharmacy 2688 24% 0% 445
4 Infectious Diseases 2020 10% 0% 195
5 Biophysics 1004 9% 0% 175
6 Chemistry, Medicinal 567 6% 0% 110
7 Biotechnology & Applied Microbiology 116 5% 0% 91
8 Cell Biology 82 6% 0% 104
9 Biochemical Research Methods 30 2% 0% 44
10 Crystallography 7 1% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL MEMBRANE BIOL 260902 2% 36% 44
2 AD TAT GENET DRUG ISTANCE 219194 2% 40% 34
3 ANTIMICROBIAL AGENTS GRP 135767 2% 29% 29
4 GENOME PL MICROBIOL 123337 1% 69% 11
5 BIOINFORMAT COMPUTAT BIOL INTER PROGRA 120097 0% 82% 9
6 UMR MD1 105665 1% 36% 18
7 UMR MD 1 98428 1% 46% 13
8 UNIT MYCOBACTERIOL 89877 1% 26% 21
9 EA2197 89693 1% 50% 11
10 UPMM 83945 1% 23% 22

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 21499 9% 1% 177
2 JOURNAL OF BACTERIOLOGY 13085 9% 1% 164
3 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 9118 4% 1% 84
4 INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS 7109 2% 1% 41
5 ACS INFECTIOUS DISEASES 4772 0% 4% 7
6 JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY 4541 1% 2% 15
7 MICROBIAL DRUG RESISTANCE 2743 1% 1% 14
8 MOLECULAR MICROBIOLOGY 2710 2% 0% 45
9 FRONTIERS IN MICROBIOLOGY 1961 1% 0% 26
10 FEMS MICROBIOLOGY LETTERS 1347 2% 0% 37

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EFFLUX PUMP INHIBITOR 708721 4% 61% 71 Search EFFLUX+PUMP+INHIBITOR Search EFFLUX+PUMP+INHIBITOR
2 EFFLUX PUMPS 514034 7% 23% 138 Search EFFLUX+PUMPS Search EFFLUX+PUMPS
3 EMRE 334534 2% 71% 29 Search EMRE Search EMRE
4 MULTIDRUG EFFLUX PUMP 301696 2% 50% 37 Search MULTIDRUG+EFFLUX+PUMP Search MULTIDRUG+EFFLUX+PUMP
5 MULTIDRUG EFFLUX 283074 1% 64% 27 Search MULTIDRUG+EFFLUX Search MULTIDRUG+EFFLUX
6 ACRB 268237 1% 66% 25 Search ACRB Search ACRB
7 TOLC 250699 1% 55% 28 Search TOLC Search TOLC
8 RND TRANSPORTERS 193137 1% 79% 15 Search RND+TRANSPORTERS Search RND+TRANSPORTERS
9 RESISTANCE NODULATION CELL DIVISION 179409 1% 100% 11 Search RESISTANCE+NODULATION+CELL+DIVISION Search RESISTANCE+NODULATION+CELL+DIVISION
10 DRUG EFFLUX PUMP 161077 1% 45% 22 Search DRUG+EFFLUX+PUMP Search DRUG+EFFLUX+PUMP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LI, XZ , PLESIAT, P , NIKAIDO, H , (2015) THE CHALLENGE OF EFFLUX-MEDIATED ANTIBIOTIC RESISTANCE IN GRAM-NEGATIVE BACTERIA.CLINICAL MICROBIOLOGY REVIEWS. VOL. 28. ISSUE 2. P. 337 -418 294 30% 78
2 LI, XZ , NIKAIDO, H , (2009) EFFLUX-MEDIATED DRUG RESISTANCE IN BACTERIA AN UPDATE.DRUGS. VOL. 69. ISSUE 12. P. 1555 -1623 283 38% 244
3 RUGGERONE, P , MURAKAMI, S , POS, KM , VARGIU, AV , (2013) RND EFFLUX PUMPS: STRUCTURAL INFORMATION TRANSLATED INTO FUNCTION AND INHIBITION MECHANISMS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 24. P. 3079 -3100 127 73% 23
4 ANES, J , MCCUSKER, MP , FANNING, S , MARTINS, M , (2015) THE INS AND OUTS OF RND EFFLUX PUMPS IN ESCHERICHIA COLI.FRONTIERS IN MICROBIOLOGY. VOL. 6. ISSUE . P. - 108 73% 8
5 OPPERMAN, TJ , NGUYEN, S , (2015) RECENT ADVANCES TOWARD A MOLECULAR MECHANISM OF EFFLUX PUMP INHIBITION.FRONTIERS IN MICROBIOLOGY. VOL. 6. ISSUE . P. - 72 86% 28
6 SYMMONS, MF , MARSHALL, RL , BAVRO, VN , (2015) ARCHITECTURE AND ROLES OF PERIPLASMIC ADAPTOR PROTEINS IN TRIPARTITE EFFLUX ASSEMBLIES.FRONTIERS IN MICROBIOLOGY. VOL. 6. ISSUE . P. - 111 76% 3
7 SUN, JJ , DENG, ZQ , YAN, AX , (2014) BACTERIAL MULTIDRUG EFFLUX PUMPS: MECHANISMS, PHYSIOLOGY AND PHARMACOLOGICAL EXPLOITATIONS.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 453. ISSUE 2. P. 254 -267 101 61% 58
8 PIDDOCK, LJV , (2006) CLINICALLY RELEVANT CHROMOSOMALLY ENCODED MULTIDRUG RESISTANCE EFFLUX PUMPS IN BACTERIA.CLINICAL MICROBIOLOGY REVIEWS. VOL. 19. ISSUE 2. P. 382-+ 115 53% 387
9 WANG, YH , VENTER, H , MA, ST , (2016) EFFLUX PUMP INHIBITORS: A NOVEL APPROACH TO COMBAT EFFLUX-MEDIATED DRUG RESISTANCE IN BACTERIA.CURRENT DRUG TARGETS. VOL. 17. ISSUE 6. P. 702 -719 82 79% 2
10 LI, XZ , NIKAIDO, H , (2004) EFFLUX-MEDIATED DRUG RESISTANCE IN BACTERIA.DRUGS. VOL. 64. ISSUE 2. P. 159-204 173 39% 355

Classes with closest relation at Level 1


Rank Class id link
1 9318 OPRD//PSEUDOMONAS AERUGINOSA//MEXXY
2 20819 TET REPRESSOR//TETRACYCLINE H ANTIPORTER//TETRACYCLINE RESISTANCE PROTEIN
3 13951 ANTISEPTIC RESISTANCE//BIOCIDE RESISTANCE//BIOCIDES
4 14430 QNR//AAC6 IB CR//PLASMID MEDIATED QUINOLONE RESISTANCE
5 23437 MODIFYING ANTIBIOTIC ACTIVITY//MODIFICATION OF RESISTANCE//GENET MICRORGANISMS
6 10698 OXYR//SOXRS REGULON//SOXR
7 10521 LACTOSE PERMEASE//PHYSIOL MICROBIOL//MACDONALD S 5 748
8 15045 BENZOAPHENOTHIAZINES//NON ANTIBIOTICS//AZAPHENOTHIAZINES
9 30741 OFF RISK ASSESSMENT COORDINAT//ANTIOXIDANTS REDOX BIOL TOXICOL//VITAS PHARMA PRIVATE LTD
10 13320 STYRENE MONOOXYGENASE//SOLVENT TOLERANCE//ORGANIC SOLVENT TOLERANCE

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