Class information for:
Level 1: PHLPP1//PHLPP//PHLPP2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
35578 95 40.5 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1220 2             PTEN//MTOR//COWDEN SYNDROME 9128
35578 1                   PHLPP1//PHLPP//PHLPP2 95

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHLPP1 authKW 2892844 13% 75% 12
2 PHLPP authKW 2089267 14% 50% 13
3 PHLPP2 authKW 609013 6% 32% 6
4 1 3 4 2 4 DIAMINO 5 METHYLPHENYLDIAZENYLPHENYLHYDRAZINYLIDENE 6 OXOCYCLOHEXA 1 4 DIENE 1 CARBOXYLIC ACID authKW 321428 1% 100% 1
5 1 AMINO 9 10 DIOXO 4 3 SULFAMOYLANILINOANTHRACENE 2 SULFONIC ACID authKW 321428 1% 100% 1
6 21T CELL LINES authKW 321428 1% 100% 1
7 AKT PHOSPHORYLATION DEUBIQUITINATION authKW 321428 1% 100% 1
8 AKT S6 RIBOSOMAL PROTEIN authKW 321428 1% 100% 1
9 ALPHA AND GAMMA VE5 authKW 321428 1% 100% 1
10 FKBP51 PHLPP AKT SIGNALING authKW 321428 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 482 37% 0% 35
2 Oncology 359 33% 0% 31
3 Biochemistry & Molecular Biology 231 42% 0% 40
4 Medicine, Research & Experimental 27 7% 0% 7
5 Biophysics 13 5% 0% 5
6 Endocrinology & Metabolism 10 5% 0% 5
7 Pharmacology & Pharmacy 6 7% 0% 7
8 Obstetrics & Gynecology 6 3% 0% 3
9 Hematology 6 3% 0% 3
10 Genetics & Heredity 4 4% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NELSON ENVIRON MED 321428 1% 100% 1
2 UMR SIGNALISAT NOYAUX INNOVAT CANCEROL 8126 160713 1% 50% 1
3 ENZE MED 107141 1% 33% 1
4 HIRSHBERG TRANSLAT PANCREAT CANC 107141 1% 33% 1
5 OVERSEA 107141 1% 33% 1
6 ZHONGNAN HOSP HEPATOBILIARY DIS 107141 1% 33% 1
7 NEURAL BIOL 80355 1% 25% 1
8 W CHINA MED PRECLIN FORENS MED 53570 1% 17% 1
9 ZHEJIANG PROV TECHNOL PLICAT MODEL OR 51421 4% 4% 4
10 KOREAN MED HLTH AGING 45917 1% 14% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER PREVENTION RESEARCH 1048 2% 0% 2
2 ONCOTARGET 938 6% 0% 6
3 JOURNAL OF GYNECOLOGIC ONCOLOGY 927 1% 0% 1
4 BIOMEDICINE & PHARMACOTHERAPY 726 3% 0% 3
5 MOLECULAR CELL 526 3% 0% 3
6 CELL DEATH AND DIFFERENTIATION 403 2% 0% 2
7 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 367 1% 0% 1
8 JOURNAL OF DIABETES RESEARCH 354 1% 0% 1
9 INTERNATIONAL JOURNAL OF ENDOCRINOLOGY 296 1% 0% 1
10 ONCOGENE 280 4% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PHLPP1 2892844 13% 75% 12 Search PHLPP1 Search PHLPP1
2 PHLPP 2089267 14% 50% 13 Search PHLPP Search PHLPP
3 PHLPP2 609013 6% 32% 6 Search PHLPP2 Search PHLPP2
4 1 3 4 2 4 DIAMINO 5 METHYLPHENYLDIAZENYLPHENYLHYDRAZINYLIDENE 6 OXOCYCLOHEXA 1 4 DIENE 1 CARBOXYLIC ACID 321428 1% 100% 1 Search 1+3+4+2+4+DIAMINO+5+METHYLPHENYLDIAZENYLPHENYLHYDRAZINYLIDENE+6+OXOCYCLOHEXA+1+4+DIENE+1+CARBOXYLIC+ACID Search 1+3+4+2+4+DIAMINO+5+METHYLPHENYLDIAZENYLPHENYLHYDRAZINYLIDENE+6+OXOCYCLOHEXA+1+4+DIENE+1+CARBOXYLIC+ACID
5 1 AMINO 9 10 DIOXO 4 3 SULFAMOYLANILINOANTHRACENE 2 SULFONIC ACID 321428 1% 100% 1 Search 1+AMINO+9+10+DIOXO+4+3+SULFAMOYLANILINOANTHRACENE+2+SULFONIC+ACID Search 1+AMINO+9+10+DIOXO+4+3+SULFAMOYLANILINOANTHRACENE+2+SULFONIC+ACID
6 21T CELL LINES 321428 1% 100% 1 Search 21T+CELL+LINES Search 21T+CELL+LINES
7 AKT PHOSPHORYLATION DEUBIQUITINATION 321428 1% 100% 1 Search AKT+PHOSPHORYLATION+DEUBIQUITINATION Search AKT+PHOSPHORYLATION+DEUBIQUITINATION
8 AKT S6 RIBOSOMAL PROTEIN 321428 1% 100% 1 Search AKT+S6+RIBOSOMAL+PROTEIN Search AKT+S6+RIBOSOMAL+PROTEIN
9 ALPHA AND GAMMA VE5 321428 1% 100% 1 Search ALPHA+AND+GAMMA+VE5 Search ALPHA+AND+GAMMA+VE5
10 FKBP51 PHLPP AKT SIGNALING 321428 1% 100% 1 Search FKBP51+PHLPP+AKT+SIGNALING Search FKBP51+PHLPP+AKT+SIGNALING

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HRIBAL, ML , MANCUSO, E , SPIGA, R , MANNINO, GC , FIORENTINO, TV , ANDREOZZI, F , SESTI, G , (2016) PHLPP PHOSPHATASES AS A THERAPEUTIC TARGET IN INSULIN RESISTANCE-RELATED DISEASES.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 20. ISSUE 6. P. 663 -675 33 41% 0
2 WARFEL, NA , NEWTON, AC , (2012) PLECKSTRIN HOMOLOGY DOMAIN LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE (PHLPP): A NEW PLAYER IN CELL SIGNALING.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 6. P. 3610-3616 19 45% 26
3 GRZECHNIK, AT , NEWTON, AC , (2016) PHLPPING THROUGH HISTORY: A DECADE IN THE LIFE OF PHLPP PHOSPHATASES.BIOCHEMICAL SOCIETY TRANSACTIONS. VOL. 44. ISSUE . P. 1675 -1682 20 38% 0
4 HOU, YC , DENG, JY , ZHANG, L , XIE, XM , GUO, XF , SUN, CY , ZHANG, RP , LIANG, H , (2015) LOWER EXPRESSION OF PH DOMAIN LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE 1 (PHLPP1) ASSOCIATION WITH POOR PROGNOSIS OF GASTRIC CANCER.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE. VOL. 8. ISSUE 11. P. 20481 -20489 12 60% 0
5 O'NEILL, AK , NIEDERST, MJ , NEWTON, AC , (2013) SUPPRESSION OF SURVIVAL SIGNALLING PATHWAYS BY THE PHOSPHATASE PHLPP.FEBS JOURNAL. VOL. 280. ISSUE 2. P. 572-583 22 28% 31
6 JACKSON, TC , BAYIR, H , IKONOMOVIC, MD , JANESKO-FELDMAN, K , MI, ZC , GAO, TY , JACKSON, EK , KOCHANEK, PM , (2015) DETECTION OF PHLPP1 ALPHA/BETA IN HUMAN AND MOUSE BRAIN BY DIFFERENT ANTI-PHLPP1 ANTIBODIES.SCIENTIFIC REPORTS. VOL. 5. ISSUE . P. - 10 67% 1
7 LI, X , STEVENS, PD , YANG, H , GULHATI, P , WANG, W , EVERS, BM , GAO, T , (2013) THE DEUBIQUITINATION ENZYME USP46 FUNCTIONS AS A TUMOR SUPPRESSOR BY CONTROLLING PHLPP-DEPENDENT ATTENUATION OF AKT SIGNALING IN COLON CANCER.ONCOGENE. VOL. 32. ISSUE 4. P. 471-478 11 46% 25
8 WANG, ZX , SHU, HH , WANG, Z , LI, GH , CUI, J , WU, H , CAI, SR , HE, WL , HE, YL , ZHAN, WH , (2013) LOSS EXPRESSION OF PHLPP1 CORRELATES WITH LYMPH NODE METASTASIS AND EXHIBITS A POOR PROGNOSIS IN PATIENTS WITH GASTRIC CANCER.JOURNAL OF SURGICAL ONCOLOGY. VOL. 108. ISSUE 7. P. 427 -432 11 48% 6
9 REYES, G , NIEDERST, M , COHEN-KATSENELSON, K , STENDER, JD , KUNKEL, MT , CHEN, MH , BROGNARD, J , SIERECKI, E , GAO, TY , NOWAK, DG , ET AL (2014) PLECKSTRIN HOMOLOGY DOMAIN LEUCINE-RICH REPEAT PROTEIN PHOSPHATASES SET THE AMPLITUDE OF RECEPTOR TYROSINE KINASE OUTPUT.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 111. ISSUE 38. P. E3957 -E3965 17 31% 1
10 ZHOU, JY , YU, XM , WANG, J , LI, T , JIN, T , LEI, DP , PAN, XL , (2015) ABERRANT EXPRESSION OF PHLPP1 AND PHLPP2 CORRELATES WITH POOR PROGNOSIS IN PATIENTS WITH HYPOPHARYNGEAL SQUAMOUS CELL CARCINOMA.PLOS ONE. VOL. 10. ISSUE 3. P. - 13 36% 4

Classes with closest relation at Level 1


Rank Class id link
1 23185 WIP1//PPM1D//CELL CYCLE CONTROL TUMORIGENESIS GRP
2 6528 PDK1//AKT//AKT2
3 33666 GIRDIN//GIV//GROWTH FACTOR RECEPTOR TYROSINE KINASE
4 6422 RHEB//RICTOR//REDD1
5 12604 MIR 133A//MICRORNA//MIR 99A
6 21034 GRB7//GRB14//GRB10
7 9167 CIP2A//PP2A//PROTEIN PHOSPHATASE 2A
8 88 MICRORNA//MIR 21//MIRNA
9 20409 MIR 506//MICRORNA 130B//MIR 200C
10 28947 DICER//DROSHA//AGO2

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