Class information for:
Level 1: WIP1//PPM1D//CELL CYCLE CONTROL TUMORIGENESIS GRP

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23185 355 42.0 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1220 2             PTEN//MTOR//COWDEN SYNDROME 9128
23185 1                   WIP1//PPM1D//CELL CYCLE CONTROL TUMORIGENESIS GRP 355

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WIP1 authKW 3355729 15% 74% 53
2 PPM1D authKW 2634183 10% 88% 35
3 CELL CYCLE CONTROL TUMORIGENESIS GRP address 774130 3% 100% 9
4 PROTEIN PHOSPHATASE 2C authKW 449469 5% 29% 18
5 WIP1 PHOSPHATASE authKW 430072 1% 100% 5
6 BIOL CHEM KITA KU address 275245 1% 80% 4
7 PP2C GAMMA authKW 258043 1% 100% 3
8 WILD TYPE P53 INDUCED PHOSPHATASE 1 authKW 258043 1% 100% 3
9 WIP1 PPM1D authKW 258043 1% 100% 3
10 PROTEIN PHOSPHATASE TYPE 2C authKW 215031 1% 50% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1391 33% 0% 116
2 Biochemistry & Molecular Biology 1171 48% 0% 171
3 Oncology 831 26% 0% 93
4 Genetics & Heredity 207 11% 0% 40
5 Biophysics 139 8% 0% 29
6 Mycology 72 2% 0% 7
7 Cell & Tissue Engineering 45 1% 0% 4
8 Medicine, Research & Experimental 23 4% 0% 15
9 Developmental Biology 15 2% 0% 6
10 Chemistry, Medicinal 8 2% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL CYCLE CONTROL TUMORIGENESIS GRP 774130 3% 100% 9
2 BIOL CHEM KITA KU 275245 1% 80% 4
3 ABERDEEN N SCOTLAND CLIN GENET SERV 86014 0% 100% 1
4 ANAESTHESIOLMOL BIOL 86014 0% 100% 1
5 ANTOINE LACASSAGNEUMR CNRS U1081 7284 86014 0% 100% 1
6 ASAN MED SCI 86014 0% 100% 1
7 DEV AGING CANC BIOCHEM 86014 0% 100% 1
8 DEV AGING CANCMEGURO KU 86014 0% 100% 1
9 EXCELLENCE ARC 86014 0% 100% 1
10 GENOME SCICHOU KU 86014 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 APOPTOSIS 2545 1% 1% 2
2 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 1731 3% 0% 10
3 ONCOGENE 1053 4% 0% 15
4 CELL CYCLE 520 1% 0% 2
5 YEAST 478 1% 0% 4
6 CELLULAR & MOLECULAR BIOLOGY RESEARCH 430 0% 1% 1
7 FRONTIERS OF MEDICINE 384 0% 0% 1
8 JAMA ONCOLOGY 380 0% 0% 1
9 TUMOR BIOLOGY 342 1% 0% 5
10 ONCOTARGET 332 2% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 WIP1 3355729 15% 74% 53 Search WIP1 Search WIP1
2 PPM1D 2634183 10% 88% 35 Search PPM1D Search PPM1D
3 PROTEIN PHOSPHATASE 2C 449469 5% 29% 18 Search PROTEIN+PHOSPHATASE+2C Search PROTEIN+PHOSPHATASE+2C
4 WIP1 PHOSPHATASE 430072 1% 100% 5 Search WIP1+PHOSPHATASE Search WIP1+PHOSPHATASE
5 PP2C GAMMA 258043 1% 100% 3 Search PP2C+GAMMA Search PP2C+GAMMA
6 WILD TYPE P53 INDUCED PHOSPHATASE 1 258043 1% 100% 3 Search WILD+TYPE+P53+INDUCED+PHOSPHATASE+1 Search WILD+TYPE+P53+INDUCED+PHOSPHATASE+1
7 WIP1 PPM1D 258043 1% 100% 3 Search WIP1+PPM1D Search WIP1+PPM1D
8 PROTEIN PHOSPHATASE TYPE 2C 215031 1% 50% 5 Search PROTEIN+PHOSPHATASE+TYPE+2C Search PROTEIN+PHOSPHATASE+TYPE+2C
9 ONCOGENIC SUSCEPTIBILITY 172029 1% 100% 2 Search ONCOGENIC+SUSCEPTIBILITY Search ONCOGENIC+SUSCEPTIBILITY
10 PPM PHOSPHATASE 172029 1% 100% 2 Search PPM+PHOSPHATASE Search PPM+PHOSPHATASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PECHACKOVA, S , BURDOVA, K , BENADA, J , KLEIBLOVA, P , JENIKOVA, G , MACUREK, L , (2016) INHIBITION OF WIP1 PHOSPHATASE SENSITIZES BREAST CANCER CELLS TO GENOTOXIC STRESS AND TO MDM2 ANTAGONIST NUTLIN-3.ONCOTARGET. VOL. 7. ISSUE 12. P. 14458 -14475 48 55% 4
2 LOWE, J , CHA, H , LEE, MO , MAZUR, SJ , APPELLA, E , FORNACE, AJ , (2012) REGULATION OF THE WIP1 PHOSPHATASE AND ITS EFFECTS ON THE STRESS RESPONSE.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 17. ISSUE . P. 1480-1498 51 52% 33
3 GILMARTIN, AG , FAITG, TH , RICHTER, M , GROY, A , SEEFELD, MA , DARCY, MG , PENG, X , FEDEROWICZ, K , YANG, JS , ZHANG, SY , ET AL (2014) ALLOSTERIC WIP1 PHOSPHATASE INHIBITION THROUGH FLAP-SUBDOMAIN INTERACTION.NATURE CHEMICAL BIOLOGY. VOL. 10. ISSUE 3. P. 181-+ 25 81% 47
4 PARK, JY , SONG, JY , KIM, HM , HAN, HS , SEOL, HS , JANG, SJ , CHOI, J , (2012) P53-INDEPENDENT EXPRESSION OF WILD-TYPE P53-INDUCED PHOSPHATASE 1 (WIP1) IN METHYLMETHANE SULFONATE-TREATED CANCER CELL LINES AND HUMAN TUMORS.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 44. ISSUE 6. P. 896-904 31 74% 9
5 GOLOUDINA, AR , KOCHETKOVA, EY , POSPELOVA, TV , DEMIDOV, ON , (2016) WIP1 PHOSPHATASE: BETWEEN P53 AND MAPK KINASES PATHWAYS.ONCOTARGET. VOL. 7. ISSUE 21. P. 31563 -31571 37 54% 1
6 ALI, AY , KIM, JY , PELLETIER, JF , VANDERHYDEN, BC , BACHVAROV, DR , TSANG, BK , (2015) AKT CONFERS CISPLATIN CHEMORESISTANCE IN HUMAN GYNECOLOGICAL CARCINOMA CELLS BY MODULATING PPM1D STABILITY.MOLECULAR CARCINOGENESIS. VOL. 54. ISSUE 11. P. 1301 -1314 35 58% 4
7 LE GUEZENNEC, X , BULAVIN, DV , (2010) WIP1 PHOSPHATASE AT THE CROSSROADS OF CANCER AND AGING.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 35. ISSUE 2. P. 109 -114 36 56% 61
8 YAGI, H , CHUMAN, Y , KOZAKAI, Y , IMAGAWA, T , TAKAHASHI, Y , YOSHIMURA, F , TANINO, K , SAKAGUCHI, K , (2012) A SMALL MOLECULE INHIBITOR OF P53-INDUCIBLE PROTEIN PHOSPHATASE PPM1D.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 22. ISSUE 1. P. 729-732 24 89% 12
9 ZHANG, YQ , SUN, H , HE, GX , LIU, A , WANG, FJ , WANG, L , (2014) WIP1 REGULATES THE PROLIFERATION AND INVASION OF NASOPHARYNGEAL CARCINOMA IN VITRO.TUMOR BIOLOGY. VOL. 35. ISSUE 8. P. 7651 -7657 28 76% 1
10 RICHTER, M , DAYARAM, T , GILMARTIN, AG , GANJI, G , PEMMASANI, SK , VAN DER KEY, H , SHOHET, JM , DONEHOWER, LA , KUMAR, R , (2015) WIP1 PHOSPHATASE AS A POTENTIAL THERAPEUTIC TARGET IN NEUROBLASTOMA.PLOS ONE. VOL. 10. ISSUE 2. P. - 29 59% 9

Classes with closest relation at Level 1


Rank Class id link
1 35578 PHLPP1//PHLPP//PHLPP2
2 4501 PROTEIN PHOSPHATASE 1//INHIBITOR 2//GLYCOGEN SYNTHASE
3 17383 BY KINASE//BACTERIAL PROTEIN KINASES//BACTERIAL PROTEIN PHOSPHORYLATION
4 35756 UFM1//UBA5//UBE1DC1
5 22276 SIGNALING SYST//INTRACELLULAR DYNAMIC//NF KAPPA B SIGNAL TRANSDUCTION NETWORK
6 9167 CIP2A//PP2A//PROTEIN PHOSPHATASE 2A
7 24258 TAK1//TAB1//TGF BETA ACTIVATED KINASE 1
8 15199 CHEK2//PALB2//CHK2
9 1860 MDM2//MDMX//MDM4
10 22795 ASK1//PP5//PROTEIN PHOSPHATASE 5

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