Class information for:
Level 1: GRB7//GRB14//GRB10

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21034 436 46.4 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
269 3       CELL BIOLOGY//CAVEOLIN 1//CAVEOLAE 44007
536 2             X LINKED AGAMMAGLOBULINEMIA//BTK//SH2 DOMAIN 14793
21034 1                   GRB7//GRB14//GRB10 436

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRB7 authKW 2042655 8% 83% 35
2 GRB14 authKW 857917 3% 88% 14
3 GRB10 authKW 687593 4% 55% 18
4 LNK authKW 405192 2% 64% 9
5 SH2B1 authKW 360163 3% 43% 12
6 RAS ASSOCIATING DOMAIN authKW 350171 1% 100% 5
7 SH2 B authKW 291808 1% 83% 5
8 GRB7 FAMILY authKW 210103 1% 100% 3
9 NON PHOSPHORYLATED CYCLIC PEPTIDE authKW 210103 1% 100% 3
10 CELL PERMEANT PEPTIDE authKW 160075 1% 57% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1454 48% 0% 211
2 Cell Biology 1265 28% 0% 124
3 Endocrinology & Metabolism 291 11% 0% 48
4 Oncology 251 14% 0% 62
5 Biophysics 224 9% 0% 40
6 Hematology 115 6% 0% 25
7 Genetics & Heredity 97 8% 0% 33
8 Medicine, Research & Experimental 96 7% 0% 29
9 Cell & Tissue Engineering 35 1% 0% 4
10 Physiology 21 3% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CEDAR SINAI MED 140069 0% 100% 2
2 CELL SIGNALLINGMOL ENDOCRINOL GRP 140069 0% 100% 2
3 ANALYT BIOPHYS CORE 70034 0% 100% 1
4 CLIN GENOMSHIBUYA KU 70034 0% 100% 1
5 CNRSU67UMR 8104 ENDOCRINOL 70034 0% 100% 1
6 DIABET DIABET IMMUNOL 70034 0% 100% 1
7 DYNAMIQUE CYTOSQUELETTE ENZYMOL BIOCHIM S 70034 0% 100% 1
8 EMERGENCY ORGAN TRANSPLANTAT INTERNAL MED 70034 0% 100% 1
9 ENDOCRINOL SECT 111H 70034 0% 100% 1
10 ENVTIRSD 70034 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL COMMUNICATION AND SIGNALING 2972 1% 1% 4
2 JOURNAL OF MOLECULAR RECOGNITION 2804 2% 1% 7
3 MOLECULAR ENDOCRINOLOGY 2088 3% 0% 13
4 JOURNAL OF BIOLOGICAL CHEMISTRY 1450 13% 0% 57
5 MOLECULAR AND CELLULAR BIOLOGY 1362 5% 0% 21
6 ONCOGENE 1098 4% 0% 17
7 PROTEIN & CELL 1034 1% 0% 3
8 VITAMINS AND HORMONES SERIES 785 0% 1% 1
9 CELL METABOLISM 428 1% 0% 3
10 FRONTIERS IN BIOSCIENCE-LANDMARK 307 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GRB7 2042655 8% 83% 35 Search GRB7 Search GRB7
2 GRB14 857917 3% 88% 14 Search GRB14 Search GRB14
3 GRB10 687593 4% 55% 18 Search GRB10 Search GRB10
4 LNK 405192 2% 64% 9 Search LNK Search LNK
5 SH2B1 360163 3% 43% 12 Search SH2B1 Search SH2B1
6 RAS ASSOCIATING DOMAIN 350171 1% 100% 5 Search RAS+ASSOCIATING+DOMAIN Search RAS+ASSOCIATING+DOMAIN
7 SH2 B 291808 1% 83% 5 Search SH2+B Search SH2+B
8 GRB7 FAMILY 210103 1% 100% 3 Search GRB7+FAMILY Search GRB7+FAMILY
9 NON PHOSPHORYLATED CYCLIC PEPTIDE 210103 1% 100% 3 Search NON+PHOSPHORYLATED+CYCLIC+PEPTIDE Search NON+PHOSPHORYLATED+CYCLIC+PEPTIDE
10 CELL PERMEANT PEPTIDE 160075 1% 57% 4 Search CELL+PERMEANT+PEPTIDE Search CELL+PERMEANT+PEPTIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DESBUQUOIS, B , CARRE, N , BURNOL, AF , (2013) REGULATION OF INSULIN AND TYPE 1 INSULIN-LIKE GROWTH FACTOR SIGNALING AND ACTION BY THE GRB10/14 AND SH2B1/B2 ADAPTOR PROTEINS.FEBS JOURNAL. VOL. 280. ISSUE 3. P. 794-816 116 75% 12
2 HOLT, LJ , SIDDLE, K , (2005) GRB10 AND GRB14: ENIGMATIC REGULATORS OF INSULIN ACTION - AND MORE?.BIOCHEMICAL JOURNAL. VOL. 388. ISSUE . P. 393-406 82 68% 91
3 VELAZQUEZ, L , (2012) THE LNK ADAPTOR PROTEIN: A KEY REGULATOR OF NORMAL AND PATHOLOGICAL HEMATOPOIESIS.ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS. VOL. 60. ISSUE 6. P. 415-429 66 70% 1
4 DENG, YP , ZHANG, MC , RIEDEL, H , (2008) MITOGENIC ROLES OF GAB 1 AND GRB 10 AS DIRECT CELLULAR PARTNERS IN THE REGULATION OF MAP KINASE SIGNALING.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 105. ISSUE 5. P. 1172-1182 60 73% 11
5 KABIR, NN , KAZI, JU , (2014) GRB10 IS A DUAL REGULATOR OF RECEPTOR TYROSINE KINASE SIGNALING.MOLECULAR BIOLOGY REPORTS. VOL. 41. ISSUE 4. P. 1985-1992 50 72% 3
6 CARIOU, B , BEREZIAT, V , MONCOQ, K , KASUS-JACOBI, A , PERDEREAU, D , LE MARCIS, V , BURNOL, AF , (2004) REGULATION AND FUNCTIONAL ROLES OF GRB14.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 9. ISSUE . P. 1626-1636 60 73% 24
7 ZHANG, MC , DENG, YP , TANDON, R , BAI, C , RIEDEL, H , (2008) ESSENTIAL ROLE OF PSM/SH2-B VARIANTS IN INSULIN RECEPTOR CATALYTIC ACTIVATION AND THE RESULTING CELLULAR RESPONSES.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 103. ISSUE 1. P. 162 -181 50 76% 7
8 KAZI, JU , RONNSTRAND, L , (2013) FLT3 SIGNALS VIA THE ADAPTER PROTEIN GRB10 AND OVEREXPRESSION OF GRB10 LEADS TO ABERRANT CELL PROLIFERATION IN ACUTE MYELOID LEUKEMIA.MOLECULAR ONCOLOGY. VOL. 7. ISSUE 3. P. 402-418 49 66% 7
9 ZHANG, MC , DENG, YP , RIEDEL, H , (2008) PSM/SH2B1 SPLICE VARIANTS: CRITICAL ROLE IN SRC CATALYTIC ACTIVATION AND THE RESULTING STAT3-MEDIATED MITOGENIC RESPONSE.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 104. ISSUE 1. P. 105 -118 47 69% 4
10 DING, LW , SUN, QY , LIN, DC , CHIEN, W , HATTORI, N , DONG, XM , GERY, S , GARG, M , DOAN, NB , SAID, JW , ET AL (2015) LNK (SH2B3): PARADOXICAL EFFECTS IN OVARIAN CANCER.ONCOGENE. VOL. 34. ISSUE 11. P. 1463 -1474 32 76% 5

Classes with closest relation at Level 1


Rank Class id link
1 12290 SH3 DOMAIN//SH2 DOMAIN//GRB2
2 9406 INSULIN RECEPTOR SUBSTRATE//INSULIN RECEPTOR SUBSTRATE 1//IRS 1
3 14390 CBL//CBL B//C CBL
4 35578 PHLPP1//PHLPP//PHLPP2
5 22610 WWP1//WW DOMAIN//CKIP 1
6 31664 TANKYRASE//TANKYRASE 1//TANKYRASE INHIBITORS
7 8755 FTO//FTO GENE//FAT MASS AND OBESITY ASSOCIATED GENE
8 17831 P66SHC//SHC//SHC FAMILY
9 1594 INSULIN RECEPTOR//LEPRECHAUNISM//DONOHUE SYNDROME
10 20035 ELOVL4//ROD OUTER SEGMENTS//STGD3

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