Class information for:
Level 1: PTEN//COWDEN SYNDROME//LHERMITTE DUCLOS DISEASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2908 2116 39.1 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1220 2             PTEN//MTOR//COWDEN SYNDROME 9128
2908 1                   PTEN//COWDEN SYNDROME//LHERMITTE DUCLOS DISEASE 2116

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PTEN authKW 2900418 34% 28% 720
2 COWDEN SYNDROME authKW 1136404 5% 69% 114
3 LHERMITTE DUCLOS DISEASE authKW 940611 3% 88% 74
4 COWDEN DISEASE authKW 754869 3% 76% 69
5 PTEN GENE authKW 406503 2% 78% 36
6 MULTIPLE HAMARTOMA SYNDROME authKW 336338 1% 90% 26
7 PTEN MMAC1 authKW 304801 1% 81% 26
8 DYSPLASTIC GANGLIOCYTOMA authKW 240475 1% 83% 20
9 BANNAYAN RILEY RUVALCABA SYNDROME authKW 232775 1% 73% 22
10 PTEN HAMARTOMA TUMOR SYNDROME authKW 192372 1% 67% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7321 31% 0% 663
2 Cell Biology 2359 19% 0% 392
3 Genetics & Heredity 2217 15% 0% 308
4 Biochemistry & Molecular Biology 1144 23% 0% 482
5 Pathology 1076 7% 0% 148
6 Dermatology 490 4% 0% 88
7 Clinical Neurology 219 6% 0% 127
8 Gastroenterology & Hepatology 155 3% 0% 72
9 Medicine, Research & Experimental 150 4% 0% 92
10 Neuroimaging 87 1% 0% 20

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN CANC GENET PROGRAM 183054 2% 30% 42
2 STANLEY SHALOM ZIELONY NURSING EXCELLENCE 130201 1% 48% 19
3 HUMAN CANC GENET GRP 127700 2% 27% 33
4 CHARLES A DANA HUMAN CANC GENET UNIT 72734 1% 46% 11
5 STANLEY SHALOM ZIELONY NURSING 60119 0% 83% 5
6 HUMAN CANC GENET PROGRAM 49722 2% 8% 46
7 GERMLINE HIGH RISK FOCUS GRP 43287 0% 100% 3
8 CANC UK HUMAN CANC GENET GRP 40066 0% 28% 10
9 CASE COMPREHENS CANC 38190 2% 5% 52
10 CANC BETH ISRAEL DEACONESS CANC 32977 0% 57% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 3706 3% 0% 69
2 CANCER RESEARCH 2550 4% 0% 85
3 HUMAN MOLECULAR GENETICS 1461 2% 0% 32
4 METHODS 1344 1% 1% 17
5 ONCOLOGY REPORTS 1175 1% 0% 29
6 JOURNAL OF MEDICAL GENETICS 1169 1% 0% 22
7 GENES CHROMOSOMES & CANCER 998 1% 0% 15
8 HEREDITARY CANCER IN CLINICAL PRACTICE 708 0% 2% 3
9 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 548 1% 0% 14
10 INTERNATIONAL JOURNAL OF ONCOLOGY 459 1% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PTEN 2900418 34% 28% 720 Search PTEN Search PTEN
2 COWDEN SYNDROME 1136404 5% 69% 114 Search COWDEN+SYNDROME Search COWDEN+SYNDROME
3 LHERMITTE DUCLOS DISEASE 940611 3% 88% 74 Search LHERMITTE+DUCLOS+DISEASE Search LHERMITTE+DUCLOS+DISEASE
4 COWDEN DISEASE 754869 3% 76% 69 Search COWDEN+DISEASE Search COWDEN+DISEASE
5 PTEN GENE 406503 2% 78% 36 Search PTEN+GENE Search PTEN+GENE
6 MULTIPLE HAMARTOMA SYNDROME 336338 1% 90% 26 Search MULTIPLE+HAMARTOMA+SYNDROME Search MULTIPLE+HAMARTOMA+SYNDROME
7 PTEN MMAC1 304801 1% 81% 26 Search PTEN+MMAC1 Search PTEN+MMAC1
8 DYSPLASTIC GANGLIOCYTOMA 240475 1% 83% 20 Search DYSPLASTIC+GANGLIOCYTOMA Search DYSPLASTIC+GANGLIOCYTOMA
9 BANNAYAN RILEY RUVALCABA SYNDROME 232775 1% 73% 22 Search BANNAYAN+RILEY+RUVALCABA+SYNDROME Search BANNAYAN+RILEY+RUVALCABA+SYNDROME
10 PTEN HAMARTOMA TUMOR SYNDROME 192372 1% 67% 20 Search PTEN+HAMARTOMA+TUMOR+SYNDROME Search PTEN+HAMARTOMA+TUMOR+SYNDROME

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SALMENA, L , CARRACEDO, A , PANDOLFI, PP , (2008) TENETS OF PTEN TUMOR SUPPRESSION.CELL. VOL. 133. ISSUE 3. P. 403 -414 88 75% 541
2 PULIDO, R , (2015) PTEN: A YIN-YANG MASTER REGULATOR PROTEIN IN HEALTH AND DISEASE.METHODS. VOL. 77-78. ISSUE . P. 3 -10 123 65% 3
3 LESLIE, NR , LONGY, M , (2016) INHERITED PTEN MUTATIONS AND THE PREDICTION OF PHENOTYPE.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 52. ISSUE . P. 30 -38 78 68% 7
4 ENG, C , (2003) PTEN: ONE GENE, MANY SYNDROMES.HUMAN MUTATION. VOL. 22. ISSUE 3. P. 183-198 89 77% 432
5 HOLLANDER, MC , BLUMENTHAL, GM , DENNIS, PA , (2011) PTEN LOSS IN THE CONTINUUM OF COMMON CANCERS, RARE SYNDROMES AND MOUSE MODELS.NATURE REVIEWS CANCER. VOL. 11. ISSUE 4. P. 289 -301 90 47% 308
6 LESLIE, NR , DOWNES, CP , (2004) PTEN FUNCTION: HOW NORMAL CELLS CONTROL IT AND TUMOUR CELLS LOSE IT.BIOCHEMICAL JOURNAL. VOL. 382. ISSUE . P. 1-11 88 69% 243
7 HOPKINS, BD , HODAKOSKI, C , BARROWS, D , MENSE, SM , PARSONS, RE , (2014) PTEN FUNCTION: THE LONG AND THE SHORT OF IT.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 39. ISSUE 4. P. 183-190 63 75% 38
8 KREIS, P , LEONDARITIS, G , LIEBERAM, I , EICKHOLT, BJ , (2014) SUBCELLULAR TARGETING AND DYNAMIC REGULATION OF PTEN: IMPLICATIONS FOR NEURONAL CELLS AND NEUROLOGICAL DISORDERS.FRONTIERS IN MOLECULAR NEUROSCIENCE. VOL. 7. ISSUE . P. - 94 57% 18
9 PILARSKI, R , BURT, R , KOHLMAN, W , PHO, L , SHANNON, KM , SWISHER, E , (2013) COWDEN SYNDROME AND THE PTEN HAMARTOMA TUMOR SYNDROME: SYSTEMATIC REVIEW AND REVISED DIAGNOSTIC CRITERIA.JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 105. ISSUE 21. P. 1607-1616 63 72% 68
10 YIN, Y , SHEN, WH , (2008) PTEN: A NEW GUARDIAN OF THE GENOME.ONCOGENE. VOL. 27. ISSUE 41. P. 5443 -5453 79 68% 146

Classes with closest relation at Level 1


Rank Class id link
1 6528 PDK1//AKT//AKT2
2 1300 MTOR//PIK3CA//PI3K INHIBITOR
3 9462 PEUTZ JEGHERS SYNDROME//LKB1//JUVENILE POLYPOSIS
4 14683 SHIP2//SHIP1//DOK
5 35578 PHLPP1//PHLPP//PHLPP2
6 14681 PROTEUS SYNDROME//MACRODACTYLY//ENCEPHALOCRANIOCUTANEOUS LIPOMATOSIS
7 6545 EGFRVIII//EGFR AMPLIFICATION//GLIOBLASTOMA
8 5678 PI3K GAMMA//PHOSPHOINOSITIDE 3 KINASE//P110 DELTA
9 22610 WWP1//WW DOMAIN//CKIP 1
10 6394 UTERINE PAPILLARY SEROUS CARCINOMA//UTERINE SEROUS CARCINOMA//ENDOMETRIAL CARCINOMA

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