Class information for:
Level 1: DOLASTATIN 10//DIDEMNIN B//CRYPTOPHYCIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14510 765 39.0 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
354 3       MICROCYSTIN//HARMFUL ALGAE//MICROCYSTIN LR 34996
1803 2             LANTIBIOTIC//OXAZOLE//DOLASTATIN 10 6283
14510 1                   DOLASTATIN 10//DIDEMNIN B//CRYPTOPHYCIN 765

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DOLASTATIN 10 authKW 1143846 4% 87% 33
2 DIDEMNIN B authKW 1048987 4% 91% 29
3 CRYPTOPHYCIN authKW 920363 4% 82% 28
4 TZT 1027 authKW 899391 3% 87% 26
5 PLITIDEPSIN authKW 704078 3% 84% 21
6 DOLASTATIN authKW 676178 3% 71% 24
7 APLIDIN authKW 528271 2% 88% 15
8 APLIDINE authKW 524319 2% 77% 17
9 KAHALALIDE F authKW 427643 2% 71% 15
10 DIDEMNINS authKW 307027 1% 77% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 2352 30% 0% 227
2 Chemistry, Medicinal 2156 16% 0% 124
3 Chemistry, Organic 2037 24% 0% 185
4 Pharmacology & Pharmacy 1156 24% 0% 186
5 Biochemical Research Methods 50 4% 0% 28
6 Chemistry, Multidisciplinary 44 8% 0% 62
7 Biochemistry & Molecular Biology 26 10% 0% 75
8 Integrative & Complementary Medicine 13 1% 0% 5
9 Plant Sciences 11 3% 0% 26
10 Chemistry, Analytical 11 3% 0% 25

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOCIEDAD UNIPERSONAL 119742 0% 100% 3
2 CANC CANC CHEMOTHER Y TOSHIMA KU 79828 0% 100% 2
3 SOC UNIPERSONAL 79828 0% 100% 2
4 COLMENAR VIEJO 76752 1% 38% 5
5 POLIGONO IND LA MINA 63858 1% 40% 4
6 NDDO 59868 0% 50% 3
7 PHARMA MAR 53217 0% 67% 2
8 BIOMED SPECIAL SURG SCI SURG EXPT MED 39914 0% 100% 1
9 BIOPHARMACEUT SHANDONG 39914 0% 100% 1
10 BIOPHYS 1 39914 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVESTIGATIONAL NEW DRUGS 14045 4% 1% 30
2 MARINE DRUGS 9940 3% 1% 22
3 CANCER CHEMOTHERAPY AND PHARMACOLOGY 3367 3% 0% 25
4 ANTI-CANCER DRUGS 1462 1% 0% 11
5 JOURNAL OF NATURAL PRODUCTS 1438 3% 0% 21
6 JOURNAL OF ORGANIC CHEMISTRY 1195 5% 0% 40
7 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 953 3% 0% 25
8 TETRAHEDRON 805 4% 0% 28
9 JOURNAL OF CARBOHYDRATES-NUCLEOSIDES-NUCLEOTIDES 686 0% 2% 1
10 CLINICAL CANCER RESEARCH 663 2% 0% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DOLASTATIN 10 1143846 4% 87% 33 Search DOLASTATIN+10 Search DOLASTATIN+10
2 DIDEMNIN B 1048987 4% 91% 29 Search DIDEMNIN+B Search DIDEMNIN+B
3 CRYPTOPHYCIN 920363 4% 82% 28 Search CRYPTOPHYCIN Search CRYPTOPHYCIN
4 TZT 1027 899391 3% 87% 26 Search TZT+1027 Search TZT+1027
5 PLITIDEPSIN 704078 3% 84% 21 Search PLITIDEPSIN Search PLITIDEPSIN
6 DOLASTATIN 676178 3% 71% 24 Search DOLASTATIN Search DOLASTATIN
7 APLIDIN 528271 2% 88% 15 Search APLIDIN Search APLIDIN
8 APLIDINE 524319 2% 77% 17 Search APLIDINE Search APLIDINE
9 KAHALALIDE F 427643 2% 71% 15 Search KAHALALIDE+F Search KAHALALIDE+F
10 DIDEMNINS 307027 1% 77% 10 Search DIDEMNINS Search DIDEMNINS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MOLINSKI, TF , DALISAY, DS , LIEVENS, SL , SALUDES, JP , (2009) DRUG DEVELOPMENT FROM MARINE NATURAL PRODUCTS.NATURE REVIEWS DRUG DISCOVERY. VOL. 8. ISSUE 1. P. 69 -85 110 44% 400
2 LEE, J , CURRANO, JN , CARROLL, PJ , JOULLIE, MM , (2012) DIDEMNINS, TAMANDARINS AND RELATED NATURAL PRODUCTS.NATURAL PRODUCT REPORTS. VOL. 29. ISSUE 3. P. 404 -424 81 84% 27
3 VERA, MD , JOULLIE, MM , (2002) NATURAL PRODUCTS AS PROBES OF CELL BIOLOGY: 20 YEARS OF DIDEMNIN RESEARCH.MEDICINAL RESEARCH REVIEWS. VOL. 22. ISSUE 2. P. 102 -145 91 78% 84
4 EISSLER, S , STONCIUS, A , NAHRWOLD, M , SEWALD, N , (2006) THE SYNTHESIS OF CRYPTOPHYCINS.SYNTHESIS-STUTTGART. VOL. . ISSUE 22. P. 3747-3789 74 84% 12
5 KITAGAKI, J , SHI, GB , MIYAUCHI, S , MURAKAMI, S , YANG, YL , (2015) CYCLIC DEPSIPEPTIDES AS POTENTIAL CANCER THERAPEUTICS.ANTI-CANCER DRUGS. VOL. 26. ISSUE 3. P. 259 -271 70 58% 5
6 WEISS, C , SAMMET, B , SEWALD, N , (2013) RECENT APPROACHES FOR THE SYNTHESIS OF MODIFIED CRYPTOPHYCINS.NATURAL PRODUCT REPORTS. VOL. 30. ISSUE 7. P. 924 -940 54 81% 9
7 DANU, A , WILLEKENS, C , RIBRAG, V , (2013) PLITIDEPSIN: AN ORPHAN DRUG.EXPERT OPINION ON ORPHAN DRUGS. VOL. 1. ISSUE 7. P. 569 -580 42 100% 1
8 NAHRWOLD, M , EISSLER, S , SEWALD, N , (2008) CRYPTOPHYCINS - HIGHLY CYTOTOXIC DEPSIPEPTIDES - HIGHLIGHTS, CHALLENGES, AND RECENT ADVANCES.CHIMICA OGGI-CHEMISTRY TODAY. VOL. 26. ISSUE 4. P. 13-16 52 91% 0
9 ALONSO-ALVAREZ, S , PARDAL, E , SANCHEZ-NIETO, D , NAVARRO, M , CABALLERO, MD , MATEOS, MV , MARTIN, A , (2017) PLITIDEPSIN: DESIGN, DEVELOPMENT, AND POTENTIAL PLACE IN THERAPY.DRUG DESIGN DEVELOPMENT AND THERAPY. VOL. 11. ISSUE . P. 253 -264 35 90% 0
10 PILARD, F , MEZRAI, A , DRICI, W , LESUR, D , MULENGI, JK , WADOUACHI, A , (2014) THE SYNTHESIS OF AN AZIRIDINYL ANALOGUE OF UNIT A OF CRYPTOPHYCIN-1.LETTERS IN ORGANIC CHEMISTRY. VOL. 11. ISSUE 4. P. 259 -267 41 79% 0

Classes with closest relation at Level 1


Rank Class id link
1 8321 MARINE CYANOBACTERIA//AERUGINOSIN//LYNGBYA MAJUSCULA
2 17826 BRYOSTATIN//BRYOSTATIN 1//APLYSIATOXIN
3 33929 TUBULYSIN//PYRROLO 1 5 BENZOXAZEPINES//PBOX
4 13664 APLYRONINE A//JASPAMIDE//THEONELLA SWINHOEI
5 5476 COMBRETASTATIN//COMBRETASTATIN A 4//VASCULAR DISRUPTING AGENTS
6 21452 SANSALVAMIDE A//BACKBONE CYCLIZATION//BACKBONE CYCLIC PEPTIDES
7 17351 DISCODERMOLIDE//LAULIMALIDE//ELEUTHEROBIN
8 25912 USTILAGINOIDEA VIRENS//RICE FALSE SMUT//VILLOSICLAVA VIRENS
9 11645 TRABECTEDIN//ET 743//SOFT TISSUE SARCOMA
10 19264 ERIBULIN//ERIBULIN MESYLATE//HALICHONDRIN B

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