Class information for:
Level 1: DISCODERMOLIDE//LAULIMALIDE//ELEUTHEROBIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17351 604 40.7 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
1 3       CHEMISTRY, ORGANIC//TETRAHEDRON LETTERS//JOURNAL OF ORGANIC CHEMISTRY 237069
288 2             CHEMISTRY, ORGANIC//ALLYLATION//TETRAHEDRON LETTERS 18901
17351 1                   DISCODERMOLIDE//LAULIMALIDE//ELEUTHEROBIN 604

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DISCODERMOLIDE authKW 1376177 6% 78% 35
2 LAULIMALIDE authKW 1166617 5% 77% 30
3 ELEUTHEROBIN authKW 862077 3% 95% 18
4 PELORUSIDE A authKW 730500 3% 85% 17
5 TACCACEAE authKW 657202 2% 100% 13
6 TACCA PLANTAGINEA authKW 505540 2% 100% 10
7 PELORUSIDE authKW 485314 2% 80% 12
8 TACCALONOLIDES authKW 459580 2% 91% 10
9 ELEUTHESIDES authKW 404432 1% 100% 8
10 TACCA CHANTRIERI authKW 372258 1% 82% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 6731 48% 0% 287
2 Chemistry, Medicinal 1780 17% 0% 100
3 Chemistry, Multidisciplinary 640 23% 0% 139
4 Pharmacology & Pharmacy 211 13% 0% 80
5 Plant Sciences 50 6% 0% 34
6 Oncology 41 6% 0% 39
7 Biochemistry & Molecular Biology 23 10% 0% 61
8 Integrative & Complementary Medicine 11 1% 0% 4
9 Chemistry, Applied 7 2% 0% 11
10 Medical Laboratory Technology 0 0% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIODISCOVERY 181209 4% 16% 22
2 BIODISCOVERY CHEM PHYS SCI 101108 0% 100% 2
3 ECCELLENZA CISI 55140 1% 18% 6
4 BIOMED MARINE 53839 1% 15% 7
5 CANC THER UET 50554 0% 100% 1
6 CHEM OCEANOG EOS 50554 0% 100% 1
7 CHEM PHYS SCI PTN 50554 0% 100% 1
8 CHIANGMAI UNIV 50554 0% 100% 1
9 CISI ECCELLENZA 50554 0% 100% 1
10 CNR UMR 8015 50554 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ORGANIC LETTERS 8916 11% 0% 67
2 TETRAHEDRON LETTERS 3145 11% 0% 68
3 RUSSIAN JOURNAL OF ORGANIC CHEMISTRY 2633 3% 0% 17
4 JOURNAL OF NATURAL PRODUCTS 1496 3% 0% 19
5 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 1299 1% 1% 4
6 CHEMISTRY & BIOLOGY 1201 1% 0% 8
7 ORGANIC PROCESS RESEARCH & DEVELOPMENT 1045 1% 0% 8
8 NATURAL PRODUCT REPORTS 888 1% 0% 5
9 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 780 4% 0% 25
10 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 671 2% 0% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DISCODERMOLIDE 1376177 6% 78% 35 Search DISCODERMOLIDE Search DISCODERMOLIDE
2 LAULIMALIDE 1166617 5% 77% 30 Search LAULIMALIDE Search LAULIMALIDE
3 ELEUTHEROBIN 862077 3% 95% 18 Search ELEUTHEROBIN Search ELEUTHEROBIN
4 PELORUSIDE A 730500 3% 85% 17 Search PELORUSIDE+A Search PELORUSIDE+A
5 TACCACEAE 657202 2% 100% 13 Search TACCACEAE Search TACCACEAE
6 TACCA PLANTAGINEA 505540 2% 100% 10 Search TACCA+PLANTAGINEA Search TACCA+PLANTAGINEA
7 PELORUSIDE 485314 2% 80% 12 Search PELORUSIDE Search PELORUSIDE
8 TACCALONOLIDES 459580 2% 91% 10 Search TACCALONOLIDES Search TACCALONOLIDES
9 ELEUTHESIDES 404432 1% 100% 8 Search ELEUTHESIDES Search ELEUTHESIDES
10 TACCA CHANTRIERI 372258 1% 82% 9 Search TACCA+CHANTRIERI Search TACCA+CHANTRIERI

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GALLAGHER, BM , (2007) MICROTUBULE-STABILIZING NATURAL PRODUCTS AS PROMISING CANCER THERAPEUTICS.CURRENT MEDICINAL CHEMISTRY. VOL. 14. ISSUE 28. P. 2959-2967 100 68% 34
2 BALLATORE, C , BRUNDEN, KR , HURYN, DM , TROJANOWSKI, JQ , LEE, VMY , SMITH, AB , (2012) MICROTUBULE STABILIZING AGENTS AS POTENTIAL TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED NEURODEGENERATIVE TAUOPATHIES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 55. ISSUE 21. P. 8979 -8996 93 44% 50
3 SMITH, AB , FREEZE, BS , (2008) (+)-DISCODERMOLIDE: TOTAL SYNTHESIS, CONSTRUCTION OF NOVEL ANALOGUES, AND BIOLOGICAL EVALUATION.TETRAHEDRON. VOL. 64. ISSUE 2. P. 261 -298 81 60% 34
4 BRACKOVIC, A , HARVEY, JE , (2015) SYNTHETIC, SEMISYNTHETIC AND NATURAL ANALOGUES OF PELORUSIDE A.CHEMICAL COMMUNICATIONS. VOL. 51. ISSUE 23. P. 4750 -4765 42 100% 3
5 ROHENA, CC , MOOBERRY, SL , (2014) RECENT PROGRESS WITH MICROTUBULE STABILIZERS: NEW COMPOUNDS, BINDING MODES AND CELLULAR ACTIVITIES.NATURAL PRODUCT REPORTS. VOL. 31. ISSUE 3. P. 335 -355 76 48% 21
6 MINEEVA, IV , (2016) CYCLOPROPANOL INTERMEDIATES IN THE SYNTHESIS OF THE C-5-C-14 FRAGMENT OF LAULIMALIDES.RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. VOL. 52. ISSUE 3. P. 355 -367 56 71% 0
7 PATERSON, I , DELGADO, O , FLORENCE, GJ , LYOTHIER, I , O'BRIEN, M , SCOTT, JP , SEREINIG, N , (2005) A SECOND-GENERATION TOTAL SYNTHESIS OF (+)-DISCODERMOLIDE: THE DEVELOPMENT OF A PRACTICAL ROUTE USING SOLELY SUBSTRATE-BASED STEREOCONTROL.JOURNAL OF ORGANIC CHEMISTRY. VOL. 70. ISSUE 1. P. 150 -160 64 72% 50
8 SHAW, SJ , (2008) THE STRUCTURE ACTIVITY RELATIONSHIP OF DISCODERMOLIDE ANALOGUES.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 8. ISSUE 3. P. 276-284 42 100% 26
9 ZHAO, Y , MU, X , DU, GH , (2016) MICROTUBULE-STABILIZING AGENTS: NEW DRUG DISCOVERY AND CANCER THERAPY.PHARMACOLOGY & THERAPEUTICS. VOL. 162. ISSUE . P. 134 -143 58 45% 6
10 PFEIFFER, B , KUZNIEWSKI, CN , WULLSCHLEGER, C , ALTMANN, KH , (2009) MACROLIDE-BASED MICROTUBULE-STABILIZING AGENTS - CHEMISTRY AND STRUCTURE-ACTIVITY RELATIONSHIPS.TUBULIN-BINDING AGENTS: SYNTHETIC, STRUCTURAL AND MECHANISTIC INSIGHTS. VOL. 286. ISSUE . P. 1 -72 93 45% 5

Classes with closest relation at Level 1


Rank Class id link
1 10628 EPOTHILONES//IXABEPILONE//PATUPILONE
2 13664 APLYRONINE A//JASPAMIDE//THEONELLA SWINHOEI
3 18927 AMPHIDINOLIDES//AMPHIDINIUM SP//AMPHIDINOL
4 14510 DOLASTATIN 10//DIDEMNIN B//CRYPTOPHYCIN
5 6873 TITANIUM ENOLATES//THIAZOLIDINETHIONES//NON CROSS LINKED POLYSTYRENE
6 5476 COMBRETASTATIN//COMBRETASTATIN A 4//VASCULAR DISRUPTING AGENTS
7 19264 ERIBULIN//ERIBULIN MESYLATE//HALICHONDRIN B
8 25513 TRANSANNULAR DIELS ALDER REACTION//TRANSANNULAR//14 BETA HYDROXYSTEROIDS
9 22187 RMN P 31//HORNER WADSWORTH EMMONS REACTION//RMN C 13
10 29565 OLIGOMYCIN A//APOPTOLIDIN//OSSAMYCIN

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