Class information for:
Level 1: SANSALVAMIDE A//BACKBONE CYCLIZATION//BACKBONE CYCLIC PEPTIDES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21452 418 35.9 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
534 3       PYRIMIDINOPHANES//SOLID PHASE SYNTHESIS//INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 19564
1200 2             PEPTAIBOL//FOLDAMERS//PEPTOIDS 9232
21452 1                   SANSALVAMIDE A//BACKBONE CYCLIZATION//BACKBONE CYCLIC PEPTIDES 418

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SANSALVAMIDE A authKW 657446 3% 75% 12
2 BACKBONE CYCLIZATION authKW 368283 3% 46% 11
3 BACKBONE CYCLIC PEPTIDES authKW 304374 1% 83% 5
4 URUKTHAPELSTATIN A authKW 292201 1% 100% 4
5 BLOCK RELEVANCE ANALYSIS authKW 219151 1% 100% 3
6 N METHYLAMINO ACID authKW 202286 1% 46% 6
7 N METHYLATED PEPTIDES authKW 202286 1% 46% 6
8 AMINO ACID PLATFORM authKW 146100 0% 100% 2
9 BENZHYDRYL ESTERS authKW 146100 0% 100% 2
10 GLOBAL DISCOVERY CHEM ANALYT NMR address 146100 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 2658 24% 0% 100
2 Chemistry, Organic 2479 35% 0% 147
3 Chemistry, Multidisciplinary 293 19% 0% 81
4 Biochemistry & Molecular Biology 250 24% 0% 99
5 Pharmacology & Pharmacy 56 9% 0% 39
6 Biophysics 27 4% 0% 17
7 Biochemical Research Methods 26 4% 0% 15
8 Crystallography 22 3% 0% 11
9 Chemistry, Applied 3 2% 0% 7
10 Computer Science, Interdisciplinary Applications 3 1% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GLOBAL DISCOVERY CHEM ANALYT NMR 146100 0% 100% 2
2 GLOBAL DISCOVERY CHEM CADD 146100 0% 100% 2
3 GLOBAL DISCOVERY CHEM MACROCYCLES 146100 0% 100% 2
4 FAK BIOL PHARMAZEUT 97399 0% 67% 2
5 PL EXPT GENOM 93918 1% 43% 3
6 CHEM LIF PROC 73050 0% 100% 1
7 DIPARTIMENTO CHIM IND ORGAN 73050 0% 100% 1
8 GLOBAL DISCOVERY CHEM ANALYT CRYSTALLOG 73050 0% 100% 1
9 GRP CIBLAGE AUTO ASSEMBLAGES FONCT 73050 0% 100% 1
10 GRP CLIN MOL ONCOHEMATOL 73050 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PEPTIDE RESEARCH 7955 2% 1% 10
2 FUTURE MEDICINAL CHEMISTRY 3911 2% 1% 7
3 JOURNAL OF MEDICINAL CHEMISTRY 2642 7% 0% 28
4 MEDCHEMCOMM 2641 2% 1% 7
5 LETTERS IN PEPTIDE SCIENCE 2353 1% 1% 4
6 INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 2157 1% 1% 4
7 JOURNAL OF PEPTIDE SCIENCE 1978 2% 0% 7
8 ORGANIC LETTERS 1771 6% 0% 25
9 BIOPOLYMERS 1345 3% 0% 11
10 AMINO ACIDS 1298 2% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SANSALVAMIDE A 657446 3% 75% 12 Search SANSALVAMIDE+A Search SANSALVAMIDE+A
2 BACKBONE CYCLIZATION 368283 3% 46% 11 Search BACKBONE+CYCLIZATION Search BACKBONE+CYCLIZATION
3 BACKBONE CYCLIC PEPTIDES 304374 1% 83% 5 Search BACKBONE+CYCLIC+PEPTIDES Search BACKBONE+CYCLIC+PEPTIDES
4 URUKTHAPELSTATIN A 292201 1% 100% 4 Search URUKTHAPELSTATIN+A Search URUKTHAPELSTATIN+A
5 BLOCK RELEVANCE ANALYSIS 219151 1% 100% 3 Search BLOCK+RELEVANCE+ANALYSIS Search BLOCK+RELEVANCE+ANALYSIS
6 N METHYLAMINO ACID 202286 1% 46% 6 Search N+METHYLAMINO+ACID Search N+METHYLAMINO+ACID
7 N METHYLATED PEPTIDES 202286 1% 46% 6 Search N+METHYLATED+PEPTIDES Search N+METHYLATED+PEPTIDES
8 AMINO ACID PLATFORM 146100 0% 100% 2 Search AMINO+ACID+PLATFORM Search AMINO+ACID+PLATFORM
9 BENZHYDRYL ESTERS 146100 0% 100% 2 Search BENZHYDRYL+ESTERS Search BENZHYDRYL+ESTERS
10 N FUNCTIONALIZED DIPEPTIDE BUILDING UNITS 146100 0% 100% 2 Search N+FUNCTIONALIZED+DIPEPTIDE+BUILDING+UNITS Search N+FUNCTIONALIZED+DIPEPTIDE+BUILDING+UNITS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BOCKUS, AT , SCHWOCHERT, JA , PYE, CR , TOWNSEND, CE , SOK, V , BEDNAREK, MA , LOKEY, RS , (2015) GOING OUT ON A LIMB: DELINEATING THE EFFECTS OF BETA-BRANCHING, N-METHYLATION, AND SIDE CHAIN SIZE ON THE PASSIVE PERMEABILITY, SOLUBILITY, AND FLEXIBILITY OF SANGUINAMIDE A ANALOGUES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 18. P. 7409 -7418 30 58% 10
2 BIRON, E , KESSLER, H , (2005) CONVENIENT SYNTHESIS OF N-METHYLAMINO ACIDS COMPATIBLE WITH FMOC SOLID-PHASE PEPTIDE SYNTHESIS.JOURNAL OF ORGANIC CHEMISTRY. VOL. 70. ISSUE 13. P. 5183 -5189 35 63% 61
3 FERNANDEZ-LLAMAZARES, AI , SPENGLER, J , ALBERICIO, F , (2015) BACKBONE N-MODIFIED PEPTIDES: HOW TO MEET THE CHALLENGE OF SECONDARY AMINE ACYLATION.BIOPOLYMERS. VOL. 104. ISSUE 5. P. 435 -452 48 36% 2
4 DI GIOIA, ML , LEGGIO, A , MALAGRINO, F , ROMIO, E , SICILIANO, C , LIGUORI, A , (2016) N-METHYLATED ALPHA-AMINO ACIDS AND PEPTIDES: SYNTHESIS AND BIOLOGICAL ACTIVITY.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 16. ISSUE 9. P. 683 -690 33 48% 1
5 KOAY, YC , RICHARDSON, NL , ZAITER, SS , TRAN, DH , KHO, J , NGUYEN, SY , LEE, KW , BUCKTON, LK , MCALPINE, SR , (2016) HITTING A MOVING TARGET: HOW DOES AN N-METHYL GROUP IMPACT BIOLOGICAL ACTIVITY?.CHEMMEDCHEM. VOL. 11. ISSUE 8. P. 881 -892 23 64% 1
6 LEGGIO, A , BELSITO, EL , DE MARCO, R , LIGUORI, A , PERRI, F , VISCOMI, MC , (2010) AN EFFICIENT PREPARATION OF N-METHYL-ALPHA-AMINO ACIDS FROM N-NOSYL-ALPHA-AMINO ACID PHENACYL ESTERS.JOURNAL OF ORGANIC CHEMISTRY. VOL. 75. ISSUE 5. P. 1386 -1392 20 83% 2
7 BOCKUS, AT , LEXA, KW , PYE, CR , KALGUTKAR, AS , GARDNER, JW , HUND, KCR , HEWITT, WM , SCHWOCHERT, JA , GLASSEY, E , PRICE, DA , ET AL (2015) PROBING THE PHYSICOCHEMICAL BOUNDARIES OF CELL PERMEABILITY AND ORAL BIOAVAILABILITY IN LIPOPHILIC MACROCYCLES INSPIRED BY NATURAL PRODUCTS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 11. P. 4581 -4589 28 42% 14
8 PAN, PS , VASKO, RC , LAPERA, SA , JOHNSON, VA , SELLERS, RP , LIN, CC , PAN, CM , DAVIS, MR , ARDI, VC , MCALPINE, SR , (2009) A COMPREHENSIVE STUDY OF SANSALVAMIDE A DERIVATIVES: THE STRUCTURE-ACTIVITY RELATIONSHIPS OF 78 DERIVATIVES IN TWO PANCREATIC CANCER CELL LINES.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 17. ISSUE 16. P. 5806 -5825 21 70% 15
9 OTRUBOVA, K , LUSHINGTON, G , VELDE, DV , MCGUIRE, KL , MCALPINE, SR , (2008) COMPREHENSIVE STUDY OF SANSALVAMIDE A DERIVATIVES AND THEIR STRUCTURE-ACTIVITY RELATIONSHIPS AGAINST DRUG-RESISTANT COLON CANCER CELL LINES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 51. ISSUE 3. P. 530 -544 20 74% 24
10 SCHWOCHERT, J , LAO, YT , PYE, CR , NAYLOR, MR , DESAI, PV , VALCARCEL, ICG , BARRETT, JA , SAWADA, G , BLANCO, MJ , LOKEY, RS , (2016) STEREOCHEMISTRY BALANCES CELL PERMEABILITY AND SOLUBILITY IN THE NATURALLY DERIVED PHEPROPEPTIN CYCLIC PEPTIDES.ACS MEDICINAL CHEMISTRY LETTERS. VOL. 7. ISSUE 8. P. 757 -761 22 52% 0

Classes with closest relation at Level 1


Rank Class id link
1 13640 COUPLING REAGENTS//RACEMIZATION FREE COUPLING//PEPTIDE COUPLING REAGENTS
2 18612 PEPTOIDS//LACTOSOME//PROTEIN MIMETIC MATERIALS
3 15710 ALPHA HELIX MIMETICS//STAPLED PEPTIDES//PROTEOMIMETICS
4 19065 AZAPEPTIDES//N BOC PROTECTION//BOC2O
5 14510 DOLASTATIN 10//DIDEMNIN B//CRYPTOPHYCIN
6 18420 BEAUVERICIN//ENNIATINS//FUSAPROLIFERIN
7 19395 ECHINOMYCIN//STREPTOMYCES ALBOFLAVUS 313//PIPERAZIC ACID
8 21496 CYCLOLINOPEPTIDE A//CYCLOLINOPEPTIDE//C2 SYMMETRICAL CONFORMATION
9 19202 VACCARIA SEGETALIS//CYCLOPEPTIDE//DIANTHUS SUPERBUS
10 14625 RIBOSOME DISPLAY//MRNA DISPLAY//FOUR BASE CODON

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