Class information for:
Level 2: ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3150 2232 29.7 50%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
3150 2             ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1 2232
5370 1                   ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1 1632
26087 1                   CYTIDINE DEAMINASE//ANTIBIOTIC FUNGICIDE//BLASTICIDIN S 263
29228 1                   DRUG DESIGN SYNTH//GUANINE DEAMINASE//ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY 190
31866 1                   EHU MED FISIOL POB 699//RABBIT PARIETAL CELLS//ATP ATP ANALOGS 147

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADENOSINE DEAMINASE authKW 416675 8% 18% 169
2 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY authKW 191505 1% 100% 14
3 CECR1 authKW 123110 0% 100% 9
4 ADENOSINE DEAMINASE DEFICIENCY authKW 99267 1% 48% 15
5 CYTIDINE DEAMINASE authKW 85583 2% 17% 36
6 DRUG DESIGN SYNTH address 82726 1% 28% 22
7 SHIFTING SPECIFICITY MODEL authKW 82074 0% 100% 6
8 ADGF authKW 56994 0% 83% 5
9 GUANINE DEAMINASE authKW 55850 0% 58% 7
10 ANTIBIOTIC FUNGICIDE authKW 48850 0% 71% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2351 30% 0% 661
2 Immunology 1154 13% 0% 279
3 Hematology 935 7% 0% 156
4 Medicine, Research & Experimental 580 7% 0% 159
5 Oncology 429 9% 0% 206
6 Pharmacology & Pharmacy 401 10% 0% 231
7 Medical Laboratory Technology 351 2% 0% 52
8 Chemistry, Medicinal 311 4% 0% 95
9 Biophysics 208 5% 0% 103
10 Cell Biology 153 6% 0% 142

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG DESIGN SYNTH 82726 1% 28% 22
2 DIPARTIMENTO BIOL MCA 35795 1% 22% 12
3 EHU MED FISIOL POB 699 27358 0% 100% 2
4 G KH BUNYATYAN BIOCHEM 18237 0% 67% 2
5 SCI WOMEN CHILD HLTH 18237 0% 67% 2
6 UNITA FISIOL GEN 18237 0% 67% 2
7 1ST INTERNAL MED 13679 0% 100% 1
8 ADOLESCENT PEDIAT RHEUMATOL 13679 0% 100% 1
9 AIDS UNITHIVACATHOSP CLIN 13679 0% 100% 1
10 ARYAN MED 13679 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 3140 1% 1% 33
2 NUCLEOSIDES & NUCLEOTIDES 2939 1% 2% 12
3 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 1906 2% 0% 49
4 CANCER RESEARCH THERAPY & CONTROL 1676 0% 3% 4
5 ENZYME 1452 0% 1% 9
6 LEUKEMIA RESEARCH 1157 1% 0% 23
7 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 1079 1% 0% 28
8 BIOCHEMISTRY 1078 3% 0% 68
9 VOPROSY MEDITSINSKOI KHIMII 980 1% 1% 13
10 REVISTA ESPANOLA DE FISIOLOGIA 968 0% 1% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADENOSINE DEAMINASE 416675 8% 18% 169 Search ADENOSINE+DEAMINASE Search ADENOSINE+DEAMINASE
2 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY 191505 1% 100% 14 Search PURINE+NUCLEOSIDE+PHOSPHORYLASE+DEFICIENCY Search PURINE+NUCLEOSIDE+PHOSPHORYLASE+DEFICIENCY
3 CECR1 123110 0% 100% 9 Search CECR1 Search CECR1
4 ADENOSINE DEAMINASE DEFICIENCY 99267 1% 48% 15 Search ADENOSINE+DEAMINASE+DEFICIENCY Search ADENOSINE+DEAMINASE+DEFICIENCY
5 CYTIDINE DEAMINASE 85583 2% 17% 36 Search CYTIDINE+DEAMINASE Search CYTIDINE+DEAMINASE
6 SHIFTING SPECIFICITY MODEL 82074 0% 100% 6 Search SHIFTING+SPECIFICITY+MODEL Search SHIFTING+SPECIFICITY+MODEL
7 ADGF 56994 0% 83% 5 Search ADGF Search ADGF
8 GUANINE DEAMINASE 55850 0% 58% 7 Search GUANINE+DEAMINASE Search GUANINE+DEAMINASE
9 ANTIBIOTIC FUNGICIDE 48850 0% 71% 5 Search ANTIBIOTIC+FUNGICIDE Search ANTIBIOTIC+FUNGICIDE
10 2 DEOXYCOFORMYCIN 47275 0% 31% 11 Search 2+DEOXYCOFORMYCIN Search 2+DEOXYCOFORMYCIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CRISTALLI, G , COSTANZI, S , LAMBERTUCCI, C , LUPIDI, G , VITTORI, S , VOLPINI, R , CAMAIONI, E , (2001) ADENOSINE DEAMINASE: FUNCTIONAL IMPLICATIONS AND DIFFERENT CLASSES OF INHIBITORS.MEDICINAL RESEARCH REVIEWS. VOL. 21. ISSUE 2. P. 105 -128 111 66% 150
2 CORTES, A , GRACIA, E , MORENO, E , MALLOL, J , LLUIS, C , CANELA, EI , CASADO, V , (2015) MOONLIGHTING ADENOSINE DEAMINASE: A TARGET PROTEIN FOR DRUG DEVELOPMENT.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 1. P. 85 -125 102 29% 7
3 ANTONIOLI, L , COLUCCI, R , LA MOTTA, C , TUCCORI, M , AWWAD, O , DA SETTIMO, F , BLANDIZZI, C , FORNAI, M , (2012) ADENOSINE DEAMINASE IN THE MODULATION OF IMMUNE SYSTEM AND ITS POTENTIAL AS A NOVEL TARGET FOR TREATMENT OF INFLAMMATORY DISORDERS.CURRENT DRUG TARGETS. VOL. 13. ISSUE 6. P. 842 -862 76 38% 21
4 GRUNEBAUM, E , COHEN, A , ROIFMAN, CM , (2013) RECENT ADVANCES IN UNDERSTANDING AND MANAGING ADENOSINE DEAMINASE AND PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCIES.CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. VOL. 13. ISSUE 6. P. 630-638 41 64% 16
5 KLOHS, WD , KRAKER, AJ , (1992) PENTOSTATIN - FUTURE-DIRECTIONS.PHARMACOLOGICAL REVIEWS. VOL. 44. ISSUE 4. P. 459-477 81 66% 21
6 ARREDONDO-VEGA, FX , SANTISTEBAN, I , DANIELS, S , TOUTAIN, S , HERSHFIELD, MS , (1998) ADENOSINE DEAMINASE DEFICIENCY: GENOTYPE-PHENOTYPE CORRELATIONS BASED ON EXPRESSED ACTIVITY OF 29 MUTANT ALLELES.AMERICAN JOURNAL OF HUMAN GENETICS. VOL. 63. ISSUE 4. P. 1049-1059 42 93% 49
7 HIRSCHHORN, R , (1995) ADENOSINE-DEAMINASE DEFICIENCY - MOLECULAR-BASIS AND RECENT DEVELOPMENTS.CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. VOL. 76. ISSUE 3. P. S219-S227 44 94% 37
8 BOSE, R , NANDAGOPAL, K , (2013) GENETIC AND BIOCHEMICAL CONSEQUENCES OF ADENOSINE DEAMINASE DEFICIENCY IN HUMANS.INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS. VOL. 50. ISSUE 5. P. 345-356 26 96% 1
9 TERASAKA, T , (2005) NON-NUCLEOSIDE ADENOSINE DEAMINASE INHIBITORS: 2000-2004.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 15. ISSUE 7. P. 817-828 38 68% 2
10 WHITMORE, KV , GASPAR, HB , (2016) ADENOSINE DEAMINASE DEFICIENCY - MORE THAN JUST AN IMMUNODEFICIENCY.FRONTIERS IN IMMUNOLOGY. VOL. 7. ISSUE . P. - 33 59% 0

Classes with closest relation at Level 2


Rank Class id link
1 3291 PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//METHIONINE DEPENDENCE
2 1752 LESCH NYHAN SYNDROME//AMP DEAMINASE//LESCH NYHAN DISEASE
3 2245 HAIRY CELL LEUKEMIA//CLADRIBINE//2 CHLORODEOXYADENOSINE
4 2341 RIBONUCLEOTIDE REDUCTASE//POLG//HYDROXYUREA
5 409 ADENOSINE//ADENOSINE RECEPTORS//ATP
6 1704 COMMON VARIABLE IMMUNODEFICIENCY//PRIMARY IMMUNODEFICIENCY//INTRAVENOUS IMMUNOGLOBULIN
7 2314 PLEURAL EFFUSION//EMPYEMA//MALIGNANT PLEURAL EFFUSION
8 2798 LEFLUNOMIDE//MIZORIBINE//DIHYDROOROTATE DEHYDROGENASE
9 3554 CU GNRH//DNA COUPLED COLUMN//STREPTOVERTICILLIUM RIMOFACIENS
10 3950 KURLOFF CELL//ALPHA NAPHTHYL ACETATE ESTERASE//ANAE

Go to start page