Class information for:
Level 1: ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5370 1632 31.6 49%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
3150 2             ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1 2232
5370 1                   ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1 1632

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADENOSINE DEAMINASE authKW 374519 8% 15% 137
2 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY authKW 261921 1% 100% 14
3 CECR1 authKW 168378 1% 100% 9
4 ADENOSINE DEAMINASE DEFICIENCY authKW 135773 1% 48% 15
5 SHIFTING SPECIFICITY MODEL authKW 112252 0% 100% 6
6 ADGF authKW 77951 0% 83% 5
7 2 DEOXYCOFORMYCIN authKW 64663 1% 31% 11
8 INSECT DERIVED GROWTH FACTOR authKW 56126 0% 100% 3
9 NUCLEOSIDE TOXICITY authKW 56126 0% 100% 3
10 ADENOSINE DEAMINASE INHIBITORS authKW 56120 0% 50% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1563 28% 0% 465
2 Immunology 1453 16% 0% 257
3 Hematology 1248 9% 0% 149
4 Medicine, Research & Experimental 685 9% 0% 142
5 Oncology 432 10% 0% 170
6 Chemistry, Medicinal 200 4% 0% 66
7 Pharmacology & Pharmacy 196 9% 0% 147
8 Cell Biology 183 7% 0% 122
9 Medical Laboratory Technology 160 2% 0% 31
10 Allergy 157 2% 0% 27

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 G KH BUNYATYAN BIOCHEM 24944 0% 67% 2
2 SCI WOMEN CHILD HLTH 24944 0% 67% 2
3 UNITA FISIOL GEN 24944 0% 67% 2
4 1ST INTERNAL MED 18709 0% 100% 1
5 ADOLESCENT PEDIAT RHEUMATOL 18709 0% 100% 1
6 AIDS UNITHIVACATHOSP CLIN 18709 0% 100% 1
7 ARYAN MED 18709 0% 100% 1
8 BEHAV SCI MOL IMMUNOL UNIT 18709 0% 100% 1
9 BIOCHEM MOL BIOLIBUB 18709 0% 100% 1
10 BIOENGN THER UT SCI 18709 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 2323 3% 0% 46
2 VOPROSY MEDITSINSKOI KHIMII 1350 1% 1% 13
3 LEUKEMIA RESEARCH 1330 1% 0% 21
4 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 1287 2% 0% 26
5 CELLULAR IMMUNOLOGY 1230 1% 0% 23
6 CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 1225 1% 0% 15
7 THYMUS 1145 0% 1% 6
8 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 1130 1% 0% 17
9 CLINICAL AND EXPERIMENTAL IMMUNOLOGY 1083 2% 0% 26
10 BIOCHEMICAL PHARMACOLOGY 922 2% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADENOSINE DEAMINASE 374519 8% 15% 137 Search ADENOSINE+DEAMINASE Search ADENOSINE+DEAMINASE
2 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY 261921 1% 100% 14 Search PURINE+NUCLEOSIDE+PHOSPHORYLASE+DEFICIENCY Search PURINE+NUCLEOSIDE+PHOSPHORYLASE+DEFICIENCY
3 CECR1 168378 1% 100% 9 Search CECR1 Search CECR1
4 ADENOSINE DEAMINASE DEFICIENCY 135773 1% 48% 15 Search ADENOSINE+DEAMINASE+DEFICIENCY Search ADENOSINE+DEAMINASE+DEFICIENCY
5 SHIFTING SPECIFICITY MODEL 112252 0% 100% 6 Search SHIFTING+SPECIFICITY+MODEL Search SHIFTING+SPECIFICITY+MODEL
6 ADGF 77951 0% 83% 5 Search ADGF Search ADGF
7 2 DEOXYCOFORMYCIN 64663 1% 31% 11 Search 2+DEOXYCOFORMYCIN Search 2+DEOXYCOFORMYCIN
8 INSECT DERIVED GROWTH FACTOR 56126 0% 100% 3 Search INSECT+DERIVED+GROWTH+FACTOR Search INSECT+DERIVED+GROWTH+FACTOR
9 NUCLEOSIDE TOXICITY 56126 0% 100% 3 Search NUCLEOSIDE+TOXICITY Search NUCLEOSIDE+TOXICITY
10 ADENOSINE DEAMINASE INHIBITORS 56120 0% 50% 6 Search ADENOSINE+DEAMINASE+INHIBITORS Search ADENOSINE+DEAMINASE+INHIBITORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CRISTALLI, G , COSTANZI, S , LAMBERTUCCI, C , LUPIDI, G , VITTORI, S , VOLPINI, R , CAMAIONI, E , (2001) ADENOSINE DEAMINASE: FUNCTIONAL IMPLICATIONS AND DIFFERENT CLASSES OF INHIBITORS.MEDICINAL RESEARCH REVIEWS. VOL. 21. ISSUE 2. P. 105 -128 107 64% 150
2 CORTES, A , GRACIA, E , MORENO, E , MALLOL, J , LLUIS, C , CANELA, EI , CASADO, V , (2015) MOONLIGHTING ADENOSINE DEAMINASE: A TARGET PROTEIN FOR DRUG DEVELOPMENT.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 1. P. 85 -125 97 28% 7
3 ANTONIOLI, L , COLUCCI, R , LA MOTTA, C , TUCCORI, M , AWWAD, O , DA SETTIMO, F , BLANDIZZI, C , FORNAI, M , (2012) ADENOSINE DEAMINASE IN THE MODULATION OF IMMUNE SYSTEM AND ITS POTENTIAL AS A NOVEL TARGET FOR TREATMENT OF INFLAMMATORY DISORDERS.CURRENT DRUG TARGETS. VOL. 13. ISSUE 6. P. 842 -862 75 38% 21
4 GRUNEBAUM, E , COHEN, A , ROIFMAN, CM , (2013) RECENT ADVANCES IN UNDERSTANDING AND MANAGING ADENOSINE DEAMINASE AND PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCIES.CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. VOL. 13. ISSUE 6. P. 630-638 41 64% 16
5 KLOHS, WD , KRAKER, AJ , (1992) PENTOSTATIN - FUTURE-DIRECTIONS.PHARMACOLOGICAL REVIEWS. VOL. 44. ISSUE 4. P. 459-477 81 66% 21
6 ARREDONDO-VEGA, FX , SANTISTEBAN, I , DANIELS, S , TOUTAIN, S , HERSHFIELD, MS , (1998) ADENOSINE DEAMINASE DEFICIENCY: GENOTYPE-PHENOTYPE CORRELATIONS BASED ON EXPRESSED ACTIVITY OF 29 MUTANT ALLELES.AMERICAN JOURNAL OF HUMAN GENETICS. VOL. 63. ISSUE 4. P. 1049-1059 42 93% 49
7 HIRSCHHORN, R , (1995) ADENOSINE-DEAMINASE DEFICIENCY - MOLECULAR-BASIS AND RECENT DEVELOPMENTS.CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. VOL. 76. ISSUE 3. P. S219-S227 44 94% 37
8 BOSE, R , NANDAGOPAL, K , (2013) GENETIC AND BIOCHEMICAL CONSEQUENCES OF ADENOSINE DEAMINASE DEFICIENCY IN HUMANS.INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS. VOL. 50. ISSUE 5. P. 345-356 26 96% 1
9 TERASAKA, T , (2005) NON-NUCLEOSIDE ADENOSINE DEAMINASE INHIBITORS: 2000-2004.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 15. ISSUE 7. P. 817-828 38 68% 2
10 WHITMORE, KV , GASPAR, HB , (2016) ADENOSINE DEAMINASE DEFICIENCY - MORE THAN JUST AN IMMUNODEFICIENCY.FRONTIERS IN IMMUNOLOGY. VOL. 7. ISSUE . P. - 33 59% 0

Classes with closest relation at Level 1


Rank Class id link
1 31866 EHU MED FISIOL POB 699//RABBIT PARIETAL CELLS//ATP ATP ANALOGS
2 13855 5 NUCLEOTIDASE//CN II//PYRIMIDINE 5 NUCLEOTIDASE
3 29228 DRUG DESIGN SYNTH//GUANINE DEAMINASE//ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY
4 13135 CLOFARABINE//CLADRIBINE//2 CHLORODEOXYADENOSINE
5 12297 SEVERE COMBINED IMMUNODEFICIENCY//OMENN SYNDROME//PRIMARY IMMUNODEFICIENCY
6 26087 CYTIDINE DEAMINASE//ANTIBIOTIC FUNGICIDE//BLASTICIDIN S
7 9868 PURINE NUCLEOSIDE PHOSPHORYLASE//CARBOHYDRATE CHEM TEAM//NUCLEOSIDE HYDROLASE
8 37055 NUCLEOSIDE OXIDASE//ANGER C REACTIVE PROTEIN CRP//ANTI INFLAMMATORY ANTI VIRAL AND ANTI LEUKAEMIC AGENTS
9 11361 PLEURAL EFFUSION//TRANSUDATE//TUBERCULOUS PLEURAL EFFUSION
10 4306 CD73//ADENOSINE RECEPTORS//ADENOSINE

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