Class information for:
Level 2: CATHEPSIN//CATHEPSIN K//CATHEPSIN B

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1744 6503 37.8 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
427 3       JOURNAL OF THE INSTITUTE OF BREWING//KERATINASE//CYSTATIN 27946
1744 2             CATHEPSIN//CATHEPSIN K//CATHEPSIN B 6503
752 1                   CATHEPSIN B//CYSTATIN//CATHEPSIN L 3104
7726 1                   MANNOSE 6 PHOSPHATE//MANNOSE 6 PHOSPHATE RECEPTOR//I CELL DISEASE 1335
11865 1                   CATHEPSIN K//PYCNODYSOSTOSIS//CATHEPSIN K INHIBITOR 948
14530 1                   CATHEPSIN D//PROCATHEPSIN D//UNITE HORMONES CANC 764
24803 1                   PAPILLON LEFEVRE SYNDROME//CATHEPSIN C//HAIM MUNK SYNDROME 301
37685 1                   CELLULAR REPRESSOR OF E1A STIMULATED GENES//CREG//CELLULAR REPRESSOR OF E1A STIMULATED GENES CREG 51

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CATHEPSIN authKW 631974 5% 40% 340
2 CATHEPSIN K authKW 621557 3% 58% 227
3 CATHEPSIN B authKW 601099 5% 37% 343
4 CATHEPSIN D authKW 485723 5% 33% 315
5 CYSTATIN authKW 439477 3% 41% 227
6 CATHEPSIN L authKW 418114 3% 42% 213
7 PAPILLON LEFEVRE SYNDROME authKW 390391 1% 96% 87
8 CYSTEINE PROTEASE authKW 271065 4% 23% 257
9 CATHEPSIN C authKW 212958 1% 74% 61
10 PYCNODYSOSTOSIS authKW 204032 1% 91% 48

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 15618 42% 0% 2725
2 Cell Biology 3659 14% 0% 900
3 Biophysics 2789 8% 0% 552
4 Oncology 2117 11% 0% 734
5 Chemistry, Medicinal 1044 5% 0% 293
6 Endocrinology & Metabolism 707 5% 0% 343
7 Pathology 426 3% 0% 195
8 Dentistry, Oral Surgery & Medicine 372 2% 0% 160
9 Medicine, Research & Experimental 362 4% 0% 260
10 Genetics & Heredity 280 4% 0% 275

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEM DRUG DESIGN 103677 0% 82% 27
2 BIOCHEM MOL STRUCT BIOL 52679 1% 23% 48
3 PROT BIOCHEM MOL BIOL 45054 0% 80% 12
4 GENET TOXICOL CANC BIOL 35292 0% 24% 32
5 DISCOVERY COMPUTAT ANALYT STRUCT SCI 32856 0% 100% 7
6 WORLD WIDE PHYS PROPERTIES 30036 0% 80% 8
7 GENE EXP S PROT PURIFICAT 28162 0% 100% 6
8 UPPSALA BIOMED VET MED CHEM BOX 575 23468 0% 100% 5
9 UNITE HORMONES CANC 21450 0% 57% 8
10 MOL MED CELL 20464 1% 12% 37

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOLOGICAL CHEMISTRY 21666 2% 4% 122
2 BIOLOGICAL CHEMISTRY HOPPE-SEYLER 21088 1% 5% 83
3 BIOCHEMICAL JOURNAL 4544 3% 1% 173
4 JOURNAL OF BIOLOGICAL CHEMISTRY 4461 6% 0% 403
5 FEBS LETTERS 2003 2% 0% 139
6 BIOMEDICA BIOCHIMICA ACTA 1998 0% 1% 30
7 JOURNAL OF BIOCHEMISTRY 1846 1% 1% 67
8 BONE 1818 1% 1% 52
9 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1692 2% 0% 100
10 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1586 1% 0% 79

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CATHEPSIN 631974 5% 40% 340 Search CATHEPSIN Search CATHEPSIN
2 CATHEPSIN K 621557 3% 58% 227 Search CATHEPSIN+K Search CATHEPSIN+K
3 CATHEPSIN B 601099 5% 37% 343 Search CATHEPSIN+B Search CATHEPSIN+B
4 CATHEPSIN D 485723 5% 33% 315 Search CATHEPSIN+D Search CATHEPSIN+D
5 CYSTATIN 439477 3% 41% 227 Search CYSTATIN Search CYSTATIN
6 CATHEPSIN L 418114 3% 42% 213 Search CATHEPSIN+L Search CATHEPSIN+L
7 PAPILLON LEFEVRE SYNDROME 390391 1% 96% 87 Search PAPILLON+LEFEVRE+SYNDROME Search PAPILLON+LEFEVRE+SYNDROME
8 CYSTEINE PROTEASE 271065 4% 23% 257 Search CYSTEINE+PROTEASE Search CYSTEINE+PROTEASE
9 CATHEPSIN C 212958 1% 74% 61 Search CATHEPSIN+C Search CATHEPSIN+C
10 PYCNODYSOSTOSIS 204032 1% 91% 48 Search PYCNODYSOSTOSIS Search PYCNODYSOSTOSIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TURK, V , STOKA, V , VASILJEVA, O , RENKO, M , SUN, T , TURK, B , TURK, D , (2012) CYSTEINE CATHEPSINS: FROM STRUCTURE, FUNCTION AND REGULATION TO NEW FRONTIERS.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1824. ISSUE 1. P. 68 -88 251 75% 218
2 KIRSCHKE, H , BARRETT, AJ , RAWLINGS, ND , (1995) PROTEINASES .1. LYSOSOMAL CYSTEINE PROTEINASES.PROTEIN PROFILE. VOL. 2. ISSUE 14. P. 1587 -1643 593 61% 101
3 FONOVIC, M , TURK, B , (2014) CYSTEINE CATHEPSINS AND EXTRACELLULAR MATRIX DEGRADATION.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1840. ISSUE 8. P. 2560 -2570 157 74% 44
4 LECAILLE, F , BROMME, D , LALMANACH, G , (2008) BIOCHEMICAL PROPERTIES AND REGULATION OF CATHEPSIN K ACTIVITY.BIOCHIMIE. VOL. 90. ISSUE 2. P. 208 -226 181 69% 68
5 DAHMS, NM , HANCOCK, MK , (2002) P-TYPE LECTINS.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. VOL. 1572. ISSUE 2-3. P. 317-340 199 67% 123
6 BERDOWSKA, I , (2004) CYSTEINE PROTEASES AS DISEASE MARKERS.CLINICA CHIMICA ACTA. VOL. 342. ISSUE 1-2. P. 41-69 164 72% 109
7 VASILJEVA, O , REINHECKEL, T , PETERS, C , TURK, D , TURK, V , TURK, B , (2007) EMERGING ROLES OF CYSTEINE CATHEPSINS IN DISEASE AND THEIR POTENTIAL AS DRUG TARGETS.CURRENT PHARMACEUTICAL DESIGN. VOL. 13. ISSUE 4. P. 387-403 136 66% 196
8 BROMME, D , PANWAR, P , TURAN, S , (2016) CATHEPSIN K OSTEOPOROSIS TRIALS, PYCNODYSOSTOSIS AND MOUSE DEFICIENCY MODELS: COMMONALITIES AND DIFFERENCES.EXPERT OPINION ON DRUG DISCOVERY. VOL. 11. ISSUE 5. P. 457 -472 119 83% 0
9 FRIZLER, M , STIRNBERG, M , SISAY, MT , GUTSCHOW, M , (2010) DEVELOPMENT OF NITRILE-BASED PEPTIDIC INHIBITORS OF CYSTEINE CATHEPSINS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 3. P. 294-322 128 71% 42
10 NICOTRA, G , CASTINO, R , FOLLO, C , PERACCHIO, C , VALENTE, G , ISIDORO, C , (2010) THE DILEMMA: DOES TISSUE EXPRESSION OF CATHEPSIN D REFLECT TUMOR MALIGNANCY? THE QUESTION: DOES THE ASSAY TRULY MIRROR CATHEPSIN D MIS-FUNCTION IN THE TUMOR?.CANCER BIOMARKERS. VOL. 7. ISSUE 1. P. 47 -64 136 72% 13

Classes with closest relation at Level 2


Rank Class id link
1 2572 UROKINASE RECEPTOR//UPAR//UPA
2 2592 JOURNAL OF THE INSTITUTE OF BREWING//MALTING//BROMELAIN
3 3012 MANNOSE RECEPTOR//ENDO180//ASIALOGLYCOPROTEIN RECEPTOR
4 2896 CALPAIN//CALPASTATIN//CALPAIN INHIBITOR
5 1128 AUTOPHAGY//BECLIN 1//LC3
6 491 GAUCHER DISEASE//LYSOSOMAL STORAGE DISEASE//MUCOPOLYSACCHARIDOSIS
7 1524 OSTEOCLAST//OSTEOPETROSIS//RANKL
8 1549 CYCLOTIDES//BOWMAN BIRK INHIBITOR//TRYPSIN INHIBITOR
9 1906 ALPHA 1 ANTITRYPSIN DEFICIENCY//ALPHA 1 ANTITRYPSIN//ALPHA1 ANTITRYPSIN DEFICIENCY
10 1547 KERATINASE//ALKALINE PROTEASE//ASPARTIC PROTEINASE

Go to start page