Class information for:
Level 1: FACTOR XII//FACTOR XI//FACTOR XI DEFICIENCY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3705 1927 36.7 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
315 3       ALLERGY//MAST CELLS//BRADYKININ 39886
1619 2             BRADYKININ//KININS//FACTOR XII 7044
3705 1                   FACTOR XII//FACTOR XI//FACTOR XI DEFICIENCY 1927

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FACTOR XII authKW 1620414 8% 65% 157
2 FACTOR XI authKW 1339849 6% 69% 122
3 FACTOR XI DEFICIENCY authKW 1085787 5% 78% 88
4 PREKALLIKREIN authKW 712111 3% 69% 65
5 HIGH MOLECULAR WEIGHT KININOGEN authKW 641289 3% 69% 59
6 KININOGEN authKW 494575 5% 33% 94
7 SOL SHERRY THROMBOSIS address 439415 6% 26% 106
8 CONTACT SYSTEM authKW 297094 2% 49% 38
9 CONTACT ACTIVATION authKW 257026 2% 43% 38
10 FACTOR XII DEFICIENCY authKW 204428 1% 65% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 36255 42% 0% 805
2 Peripheral Vascular Diseases 10593 22% 0% 426
3 Biochemistry & Molecular Biology 1205 24% 0% 464
4 Medicine, Research & Experimental 640 8% 0% 152
5 Immunology 146 6% 0% 117
6 Medical Laboratory Technology 75 1% 0% 25
7 Biophysics 62 3% 0% 62
8 Pathology 31 2% 0% 36
9 Allergy 23 1% 0% 14
10 Medicine, General & Internal 16 3% 0% 62

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOL SHERRY THROMBOSIS 439415 6% 26% 106
2 AMALIA BIRON THROMBOSIS HEMOSTASIS 62700 1% 23% 17
3 KENT HAEMOPHILIA 58670 1% 37% 10
4 KONISHI MUSC INFLAMMAT 43870 0% 46% 6
5 BIOENGN ORGAN CHEM 42249 0% 67% 4
6 MED SOL SHERRY THROMBOSIS 35648 0% 75% 3
7 PULM CRIT CARE ASTHMA ALLERGY 35648 0% 75% 3
8 DISCOVERY CHEM CARDIOVASC BIOL 31689 0% 100% 2
9 CHEM UTILIZAT ANIM OURCES 23763 0% 50% 3
10 KAROLINSKA UNIV HOSP SOLNA L1 00 21124 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THROMBOSIS RESEARCH 26073 7% 1% 130
2 THROMBOSIS AND HAEMOSTASIS 25150 7% 1% 126
3 BLOOD COAGULATION & FIBRINOLYSIS 20319 3% 2% 65
4 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 16005 3% 2% 63
5 BLOOD 10800 8% 0% 154
6 IMMUNOPHARMACOLOGY 6825 1% 2% 24
7 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 6584 2% 1% 41
8 HAEMOPHILIA 6249 2% 1% 35
9 SEMINARS IN THROMBOSIS AND HEMOSTASIS 3134 1% 1% 23
10 ACTA PHARMACOLOGICA ET TOXICOLOGICA 3114 1% 1% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FACTOR XII 1620414 8% 65% 157 Search FACTOR+XII Search FACTOR+XII
2 FACTOR XI 1339849 6% 69% 122 Search FACTOR+XI Search FACTOR+XI
3 FACTOR XI DEFICIENCY 1085787 5% 78% 88 Search FACTOR+XI+DEFICIENCY Search FACTOR+XI+DEFICIENCY
4 PREKALLIKREIN 712111 3% 69% 65 Search PREKALLIKREIN Search PREKALLIKREIN
5 HIGH MOLECULAR WEIGHT KININOGEN 641289 3% 69% 59 Search HIGH+MOLECULAR+WEIGHT+KININOGEN Search HIGH+MOLECULAR+WEIGHT+KININOGEN
6 KININOGEN 494575 5% 33% 94 Search KININOGEN Search KININOGEN
7 CONTACT SYSTEM 297094 2% 49% 38 Search CONTACT+SYSTEM Search CONTACT+SYSTEM
8 CONTACT ACTIVATION 257026 2% 43% 38 Search CONTACT+ACTIVATION Search CONTACT+ACTIVATION
9 FACTOR XII DEFICIENCY 204428 1% 65% 20 Search FACTOR+XII+DEFICIENCY Search FACTOR+XII+DEFICIENCY
10 FXI DEFICIENCY 191262 1% 93% 13 Search FXI+DEFICIENCY Search FXI+DEFICIENCY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 COLMAN, RW , SCHMAIER, AH , (1997) CONTACT SYSTEM: A VASCULAR BIOLOGY MODULATOR WITH ANTICOAGULANT, PROFIBRINOLYTIC, ANTIADHESIVE, AND PROINFLAMMATORY ATTRIBUTES.BLOOD. VOL. 90. ISSUE 10. P. 3819 -3843 165 72% 325
2 HE, R , CHEN, D , HE, SL , (2012) FACTOR XI: HEMOSTASIS, THROMBOSIS, AND ANTITHROMBOSIS.THROMBOSIS RESEARCH. VOL. 129. ISSUE 5. P. 541-550 117 83% 17
3 GAILANI, D , BANE, CE , GRUBER, A , (2015) FACTOR XI AND CONTACT ACTIVATION AS TARGETS FOR ANTITHROMBOTIC THERAPY.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 13. ISSUE 8. P. 1383 -1395 77 82% 19
4 JOSEPH, K , KAPLAN, AP , (2005) FORMATION OF BRADYKININ: A MAJOR CONTRIBUTOR TO THE INNATE INFLAMMATORY RESPONSE.ADVANCES IN IMMUNOLOGY, VOL 86. VOL. 86. ISSUE . P. 159 -208 128 73% 82
5 WOODRUFF, RS , SULLENGER, B , BECKER, RC , (2011) THE MANY FACES OF THE CONTACT PATHWAY AND THEIR ROLE IN THROMBOSIS.JOURNAL OF THROMBOSIS AND THROMBOLYSIS. VOL. 32. ISSUE 1. P. 9 -20 96 81% 20
6 DUGA, S , SALOMON, O , (2013) CONGENITAL FACTOR XI DEFICIENCY: AN UPDATE.SEMINARS IN THROMBOSIS AND HEMOSTASIS. VOL. 39. ISSUE 6. P. 621-631 79 86% 28
7 SCHMAIER, AH , (2016) THE CONTACT ACTIVATION AND KALLIKREIN/KININ SYSTEMS: PATHOPHYSIOLOGIC AND PHYSIOLOGIC ACTIVITIES.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 14. ISSUE 1. P. 28 -39 53 63% 13
8 EMSLEY, J , MCEWAN, PA , GAILANI, D , (2010) STRUCTURE AND FUNCTION OF FACTOR XI.BLOOD. VOL. 115. ISSUE 13. P. 2569 -2577 76 79% 42
9 KAPLAN, AP , JOSEPH, K , (2014) PATHOGENIC MECHANISMS OF BRADYKININ MEDIATED DISEASES: DYSREGULATION OF AN INNATE INFLAMMATORY PATHWAY.ADVANCES IN IMMUNOLOGY, VOL 121. VOL. 121. ISSUE . P. 41-89 83 57% 25
10 KAPLAN, AP , JOSEPH, K , SHIBAYAMA, Y , REDDIGARI, S , GHEBREHIWET, B , SILVERBERG, M , (1997) THE INTRINSIC COAGULATION/KININ-FORMING CASCADE: ASSEMBLY IN PLASMA AND CELL SURFACES IN INFLAMMATION.ADVANCES IN IMMUNOLOGY, VOL 66. VOL. 66. ISSUE . P. 225-272 107 77% 58

Classes with closest relation at Level 1


Rank Class id link
1 36613 PROLYLCARBOXYPEPTIDASE//PRCP//ANGIOTENSINASE C
2 3345 HEREDITARY ANGIOEDEMA//C1 INHIBITOR//ANGIOEDEMA
3 17027 FACTOR VII DEFICIENCY//FACTOR X DEFICIENCY//FVII DEFICIENCY
4 5927 KALLISTATIN//KALLIKREIN//TISSUE KALLIKREIN
5 17915 THROMBIN GENERATION//THROMBIN GENERATION ASSAY//ENDOGENOUS THROMBIN POTENTIAL
6 34458 FSAP//FACTOR VII ACTIVATING PROTEASE//PLASMA HYALURONAN BINDING PROTEIN
7 35066 HOTEL DIEU HEMATOL//PYRUVIC AND LACTIC ACIDS//ELECTRODE ADSORPTION
8 25433 HISTIDINE RICH GLYCOPROTEIN//HRG//HISTIDINE PROLINE RICH GLYCOPROTEIN
9 15448 PHYS BIOCHEM BLOOD//THROMBUS GROWTH//DAMPED OSCILLATION RHEOMETER
10 881 BRADYKININ//KININS//B 2 RECEPTOR

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