Class information for:
Level 2: PACLITAXEL//TAXANES//EPOTHILONES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1102 9807 34.4 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
216 3       NON SMALL CELL LUNG CANCER//LUNG CANCER//THORAC SURG 51214
1102 2             PACLITAXEL//TAXANES//EPOTHILONES 9807
2951 1                   TAXACEAE//TAXOIDS//TAXUS CUSPIDATA 2104
2966 1                   METASTATIC BREAST CANCER//VINORELBINE//DOCETAXEL 2101
6731 1                   CHEMOTHERAPY INDUCED PERIPHERAL NEUROPATHY//GOSHAJINKIGAN//CIPN 1450
7277 1                   PACLITAXEL//CREMOPHOR EL//DOCETAXEL 1386
10628 1                   EPOTHILONES//IXABEPILONE//PATUPILONE 1047
14245 1                   VINFLUNINE//VINCA ALKALOIDS//VINCRISTINE 782
15859 1                   TAXOL//PACLITAXEL//BCL 2 PHOSPHORYLATION 688
26652 1                   NOSCAPINE//NOSCAPINOIDS//AMINO NOSCAPINE 249

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 PACLITAXEL authKW 874065 13% 21% 1310
2 TAXANES authKW 571998 5% 40% 461
3 EPOTHILONES authKW 553048 2% 78% 229
4 TAXOL authKW 519320 5% 36% 463
5 METASTATIC BREAST CANCER authKW 496650 5% 32% 503
6 TAXACEAE authKW 400241 2% 79% 162
7 TAXOIDS authKW 366977 2% 72% 164
8 DOCETAXEL authKW 338341 6% 18% 621
9 IXABEPILONE authKW 248162 1% 77% 103
10 VINORELBINE authKW 230335 3% 28% 264

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 73615 45% 1% 4414
2 Pharmacology & Pharmacy 10234 21% 0% 2031
3 Chemistry, Medicinal 5232 8% 0% 738
4 Chemistry, Organic 1801 8% 0% 758
5 Biochemical Research Methods 357 3% 0% 295
6 Chemistry, Analytical 320 4% 0% 397
7 Plant Sciences 318 4% 0% 410
8 Integrative & Complementary Medicine 265 1% 0% 76
9 Biotechnology & Applied Microbiology 156 3% 0% 322
10 Chemistry, Multidisciplinary 142 6% 0% 573

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PL BIOORGAN CHEMAOBA KU 42855 0% 42% 33
2 MED ONCOL 34282 7% 2% 725
3 ANTINEOPLAST PHARMACOL 31097 0% 50% 20
4 UNIT NEUROONCOL 28994 0% 55% 17
5 NEW MAT BIOL 21782 0% 100% 7
6 NO ALBERTA BREAST CANC PROGRAM 21782 0% 100% 7
7 BIOMED MASS SPE OMETRY UNIT 20552 0% 37% 18
8 NEUROSCI BIOMED TECHNOL 16024 0% 15% 35
9 BREAST CANC MED SERV 15812 0% 18% 29
10 PRECLIN PHARMACOL CORE IL 15313 0% 62% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 43844 3% 4% 323
2 SEMINARS IN ONCOLOGY 39151 3% 5% 257
3 ANTI-CANCER DRUGS 22673 2% 5% 155
4 ANNALS OF ONCOLOGY 17827 2% 3% 219
5 CLINICAL BREAST CANCER 12170 1% 7% 55
6 JOURNAL OF CLINICAL ONCOLOGY 11918 3% 2% 253
7 INVESTIGATIONAL NEW DRUGS 8663 1% 3% 85
8 BREAST CANCER RESEARCH AND TREATMENT 8314 1% 2% 141
9 ONCOLOGY 6834 1% 2% 94
10 EUROPEAN JOURNAL OF CANCER 6060 1% 1% 142

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 PACLITAXEL 874065 13% 21% 1310 Search PACLITAXEL Search PACLITAXEL
2 TAXANES 571998 5% 40% 461 Search TAXANES Search TAXANES
3 EPOTHILONES 553048 2% 78% 229 Search EPOTHILONES Search EPOTHILONES
4 TAXOL 519320 5% 36% 463 Search TAXOL Search TAXOL
5 METASTATIC BREAST CANCER 496650 5% 32% 503 Search METASTATIC+BREAST+CANCER Search METASTATIC+BREAST+CANCER
6 TAXACEAE 400241 2% 79% 162 Search TAXACEAE Search TAXACEAE
7 TAXOIDS 366977 2% 72% 164 Search TAXOIDS Search TAXOIDS
8 DOCETAXEL 338341 6% 18% 621 Search DOCETAXEL Search DOCETAXEL
9 IXABEPILONE 248162 1% 77% 103 Search IXABEPILONE Search IXABEPILONE
10 VINORELBINE 230335 3% 28% 264 Search VINORELBINE Search VINORELBINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, YF , SHI, QW , DONG, M , KIYOTA, H , GU, YC , CONG, B , (2011) NATURAL TAXANES: DEVELOPMENTS SINCE 1828.CHEMICAL REVIEWS. VOL. 111. ISSUE 12. P. 7652-7709 341 87% 43
2 FEHRENBACHER, JC , (2015) CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY.MOLECULAR AND CELL BIOLOGY OF PAIN. VOL. 131. ISSUE . P. 471 -508 184 69% 7
3 HERSHMAN, DL , LACCHETTI, C , DWORKIN, RH , SMITH, EML , BLEEKER, J , CAVALETTI, G , CHAUHAN, C , GAVIN, P , LAVINO, A , LUSTBERG, MB , ET AL (2014) PREVENTION AND MANAGEMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY IN SURVIVORS OF ADULT CANCERS: AMERICAN SOCIETY OF CLINICAL ONCOLOGY CLINICAL PRACTICE GUIDELINE.JOURNAL OF CLINICAL ONCOLOGY. VOL. 32. ISSUE 18. P. 1941 -+ 75 88% 107
4 PARMAR, VS , JHA, A , BISHT, KS , TANEJA, P , SINGH, SK , KUMAR, A , POONAM , JAIN, R , OLSEN, CE , (1999) CONSTITUENTS OF THE YEW TREES.PHYTOCHEMISTRY. VOL. 50. ISSUE 8. P. 1267 -1304 139 96% 127
5 PARK, SB , GOLDSTEIN, D , KRISHNAN, AV , LIN, CSY , FRIEDLANDER, ML , CASSIDY, J , KOLTZENBURG, M , KIERNAN, MC , (2013) CHEMOTHERAPY-INDUCED PERIPHERAL NEUROTOXICITY: A CRITICAL ANALYSIS.CA-A CANCER JOURNAL FOR CLINICIANS. VOL. 63. ISSUE 6. P. 419-437 121 61% 55
6 HAN, YQ , SMITH, MT , (2013) PATHOBIOLOGY OF CANCER CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (CIPN).FRONTIERS IN PHARMACOLOGY. VOL. 4. ISSUE . P. - 120 70% 25
7 ALTMANN, KH , PFEIFFER, B , ARSENIYADIS, S , PRATT, BA , NICOLAOU, KC , (2007) THE CHEMISTRY AND BIOLOGY OF EPOTHILONES - THE WHEEL KEEPS TURNING.CHEMMEDCHEM. VOL. 2. ISSUE 4. P. 396 -423 119 83% 65
8 ARGYRIOU, AA , BRUNA, J , MARMIROLI, P , CAVALETTI, G , (2012) CHEMOTHERAPY-INDUCED PERIPHERAL NEUROTOXICITY (CIPN): AN UPDATE.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 82. ISSUE 1. P. 51 -77 124 57% 95
9 AVAN, A , POSTMA, TJ , CERESA, C , AVAN, A , CAVALETTI, G , GIOVANNETTI, E , PETERS, GJ , (2015) PLATINUM-INDUCED NEUROTOXICITY AND PREVENTIVE STRATEGIES: PAST, PRESENT, AND FUTURE.ONCOLOGIST. VOL. 20. ISSUE 4. P. 411 -432 109 58% 27
10 KAISER, S , MULLER, JJ , FROEHLICH, PE , GNOATTO, SCB , BERGOLD, AM , (2013) FROM BACTERIA TO ANTINEOPLASTIC: EPOTHILONES A SUCCESSFUL HISTORY.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 7. P. 1057-1068 103 88% 6

Classes with closest relation at Level 2


Rank Class id link
1 2644 COMBRETASTATIN//COMBRETASTATIN A 4//VASCULAR DISRUPTING AGENTS
2 1422 XRCC1//GEMCITABINE//ERCC1
3 3290 HAND FOOT SYNDROME//HYPERSENSITIVITY REACTION//RADIATION RECALL
4 994 BREAST CANCER//BREAST CONSERVING THERAPY//BREAST CONSERVING SURGERY
5 1176 THYMIDYLATE SYNTHASE//THYMIDINE PHOSPHORYLASE//5 FLUOROURACIL
6 1567 KINESIN//MICROTUBULES//STATHMIN
7 747 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1
8 2496 IFOSFAMIDE//CHEMOSENSITIVITY TEST//MESNA
9 1065 CISPLATIN//NEPHROTOXICITY//PLATINUMII COMPLEXES
10 1905 AGROBACTERIUM RHIZOGENES//HAIRY ROOTS//CATHARANTHUS ROSEUS

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