Class information for:
Level 2: CISPLATIN//NEPHROTOXICITY//PLATINUMII COMPLEXES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1065 9996 36.3 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
489 3       CISPLATIN//STABILITY CONSTANTS//JOURNAL OF INORGANIC BIOCHEMISTRY 23107
1065 2             CISPLATIN//NEPHROTOXICITY//PLATINUMII COMPLEXES 9996
879 1                   TRANSPLATIN//TRANSPLATINUM//BBR3464 2991
3335 1                   CISPLATIN//NEPHROTOXICITY//CISPLATIN NEPHROTOXICITY 2005
5887 1                   SATRAPLATIN//JM216//PLATINUM BASED DRUG 1563
10766 1                   ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE 1037
14457 1                   CISPLATIN RESISTANCE//RAT OVARIAN TUMOR CELL LINES//TCRP1 768
20988 1                   LEHRSTUHL PHARMAZEUT CHEM 2//GRP RECH ONCOL ENDOCRINOL MOL//PORPHYRIN PLATINUM CONJUGATES 437
22025 1                   DRUG EFFECT ON BRAIN//PT 191 CISPLATIN//LIPOPLATIN TM 396
22427 1                   CISPLATIN AQUATED SPECIES//MONOHYDRATED CISPLATIN//PLASMA ULTRAFILTRATES 381
27949 1                   COORDINAT CHEM SECT//HNMR UNIT//5 AMINO 1 10 PHENANTHROLINE 217
28723 1                   INTRAMOLECULAR SUBSTITUTION//OXOPLATINUM//THREE DIMENSIONAL LIKE PROLIFERATION PATTERNS 201

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 CISPLATIN authKW 736630 16% 15% 1565
2 NEPHROTOXICITY authKW 172420 4% 13% 432
3 PLATINUMII COMPLEXES authKW 152249 1% 38% 132
4 PLATINUM COMPLEXES authKW 148793 2% 21% 228
5 CARBOPLATIN authKW 86348 3% 10% 271
6 TRANSPLATIN authKW 77371 0% 69% 37
7 CANCER CHEMOTHERAPY AND PHARMACOLOGY journal 71915 4% 6% 417
8 ETOPOSIDE authKW 69733 2% 11% 212
9 CISPLATIN RESISTANCE authKW 69401 1% 23% 97
10 PLATINUM DRUGS authKW 69096 0% 46% 49

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 26067 28% 0% 2751
2 Chemistry, Inorganic & Nuclear 22843 18% 0% 1763
3 Pharmacology & Pharmacy 9906 20% 0% 2025
4 Chemistry, Medicinal 4651 7% 0% 708
5 Toxicology 2773 6% 0% 572
6 Chemistry, Multidisciplinary 1815 12% 0% 1161
7 Biochemistry & Molecular Biology 1735 15% 0% 1529
8 Urology & Nephrology 356 3% 0% 252
9 Biophysics 230 3% 0% 291
10 Chemistry, Analytical 195 4% 0% 351

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PLATINUM BASED DRUG 48845 0% 100% 16
2 LEHRSTUHL PHARMAZEUT CHEM 2 33814 0% 92% 12
3 JIANGSU PROV HITECH BIOMED 29396 0% 28% 35
4 SERV FARMACOL TOSSICOL 24726 0% 90% 9
5 MOE MED CHEM MOL DIAGNOST 22476 0% 82% 9
6 GRP RECH ONCOL ENDOCRINOL MOL 15023 0% 62% 8
7 EXPTL CHEMOTHER Y TOSHIMA KU 12718 0% 83% 5
8 IST ANAL TECNOL FARMACEUT 12211 0% 100% 4
9 PLATFORM TRANSLAT CANC THER Y 11821 0% 26% 15
10 HEAVY MET 11208 0% 12% 30

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 71915 4% 6% 417
2 JOURNAL OF INORGANIC BIOCHEMISTRY 58023 3% 6% 328
3 INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY 21360 1% 9% 79
4 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 12687 1% 5% 92
5 INORGANICA CHIMICA ACTA 10289 2% 1% 243
6 ANTI-CANCER DRUGS 9001 1% 3% 99
7 CANCER TREATMENT REPORTS 7661 1% 3% 75
8 INORGANIC CHEMISTRY 7332 3% 1% 335
9 ARCHIV DER PHARMAZIE 4859 1% 2% 84
10 METALLOMICS 4245 0% 4% 38

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 CISPLATIN 736630 16% 15% 1565 Search CISPLATIN Search CISPLATIN
2 NEPHROTOXICITY 172420 4% 13% 432 Search NEPHROTOXICITY Search NEPHROTOXICITY
3 PLATINUMII COMPLEXES 152249 1% 38% 132 Search PLATINUMII+COMPLEXES Search PLATINUMII+COMPLEXES
4 PLATINUM COMPLEXES 148793 2% 21% 228 Search PLATINUM+COMPLEXES Search PLATINUM+COMPLEXES
5 CARBOPLATIN 86348 3% 10% 271 Search CARBOPLATIN Search CARBOPLATIN
6 TRANSPLATIN 77371 0% 69% 37 Search TRANSPLATIN Search TRANSPLATIN
7 ETOPOSIDE 69733 2% 11% 212 Search ETOPOSIDE Search ETOPOSIDE
8 CISPLATIN RESISTANCE 69401 1% 23% 97 Search CISPLATIN+RESISTANCE Search CISPLATIN+RESISTANCE
9 PLATINUM DRUGS 69096 0% 46% 49 Search PLATINUM+DRUGS Search PLATINUM+DRUGS
10 JM216 67628 0% 92% 24 Search JM216 Search JM216

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JOHNSTONE, TC , SUNTHARALINGAM, K , LIPPARD, SJ , (2016) THE NEXT GENERATION OF PLATINUM DRUGS: TARGETED PT(II) AGENTS, NANOPARTICLE DELIVERY, AND PT(IV) PRODRUGS.CHEMICAL REVIEWS. VOL. 116. ISSUE 5. P. 3436 -3486 302 62% 56
2 WILSON, JJ , LIPPARD, SJ , (2014) SYNTHETIC METHODS FOR THE PREPARATION OF PLATINUM ANTICANCER COMPLEXES.CHEMICAL REVIEWS. VOL. 114. ISSUE 8. P. 4470 -4495 244 77% 100
3 OUN, R , WHEATE, NJ , WALKER, S , CRAIG, GE , (2010) THE STATUS OF PLATINUM ANTICANCER DRUGS IN THE CLINIC AND IN CLINICAL TRIALS.DALTON TRANSACTIONS. VOL. 39. ISSUE 35. P. 8113 -8127 136 74% 474
4 WONG, E , GIANDOMENICO, CM , (1999) CURRENT STATUS OF PLATINUM-BASED ANTITUMOR DRUGS.CHEMICAL REVIEWS. VOL. 99. ISSUE 9. P. 2451 -2466 138 87% 1303
5 JAKUPEC, MA , GALANSKI, M , KEPPLER, BK , (2003) TUMOUR-INHIBITING PLATINUM COMPLEXES-STATE OF THE ART AND FUTURE PERSPECTIVES.REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY, VOL 146. VOL. 146. ISSUE . P. 1 -53 214 72% 311
6 JAMIESON, ER , LIPPARD, SJ , (1999) STRUCTURE, RECOGNITION, AND PROCESSING OF CISPLATIN-DNA ADDUCTS.CHEMICAL REVIEWS. VOL. 99. ISSUE 9. P. 2467-2498 163 55% 1671
7 MONTANA, AM , BATALLA, C , (2009) THE RATIONAL DESIGN OF ANTICANCER PLATINUM COMPLEXES: THE IMPORTANCE OF THE STRUCTURE-ACTIVITY RELATIONSHIP.CURRENT MEDICINAL CHEMISTRY. VOL. 16. ISSUE 18. P. 2235 -2260 198 74% 69
8 GALANSKI, M , JAKUPEC, MA , KEPPLER, BK , (2005) UPDATE OF THE PRECLINICAL SITUATION OF ANTICANCER PLATINUM COMPLEXES: NOVEL DESIGN STRATEGIES AND INNOVATIVE ANALYTICAL APPROACHES.CURRENT MEDICINAL CHEMISTRY. VOL. 12. ISSUE 18. P. 2075-2094 131 81% 340
9 PABLA, N , DONG, Z , (2008) CISPLATIN NEPHROTOXICITY: MECHANISMS AND RENOPROTECTIVE STRATEGIES.KIDNEY INTERNATIONAL. VOL. 73. ISSUE 9. P. 994-1007 103 72% 504
10 BERNERS-PRICE, SJ , RONCONI, L , SADLER, PJ , (2006) INSIGHTS INTO THE MECHANISM OF ACTION OF PLATINUM ANTICANCER DRUGS FROM MULTINUCLEAR NMR SPECTROSCOPY.PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY. VOL. 49. ISSUE 1. P. 65-98 133 89% 89

Classes with closest relation at Level 2


Rank Class id link
1 3605 COCONUT WATER//VIRGIN COCONUT OIL//KINETIN RIBOSIDE
2 1439 DNA BINDING//RESONANCE LIGHT SCATTERING//RESONANCE RAYLEIGH SCATTERING
3 3163 MX CHAIN//MMX CHAIN//ONE DIMENSIONAL METAL COMPLEX
4 2496 IFOSFAMIDE//CHEMOSENSITIVITY TEST//MESNA
5 1225 CYCLOMETALLATION//CHEMISTRY, INORGANIC & NUCLEAR//JOURNAL OF ORGANOMETALLIC CHEMISTRY
6 1422 XRCC1//GEMCITABINE//ERCC1
7 3533 TITANOCENE DICHLORIDE//ORGANOTIN POLYMERS//VANADOCENE DICHLORIDE
8 3289 GENTAMICIN//NEPHROTOXICITY//GENTAMICIN INDUCED NEPHROTOXICITY
9 4037 ARSONOLIPIDS//ARSONIC ACIDS//ARSONOLIPOSOMES
10 1102 PACLITAXEL//TAXANES//EPOTHILONES

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