Class information for:
Level 1: MOL PATHOL ULTRASTRUCT//ENDOTHELIN AXIS//ZIBOTENTAN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16384 656 40.4 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
668 3       ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
1078 2             ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
16384 1                   MOL PATHOL ULTRASTRUCT//ENDOTHELIN AXIS//ZIBOTENTAN 656

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL PATHOL ULTRASTRUCT address 1163653 5% 83% 30
2 ENDOTHELIN AXIS authKW 523641 2% 75% 15
3 ZIBOTENTAN authKW 455336 2% 65% 15
4 ATRASENTAN authKW 447666 4% 42% 23
5 ZD4054 authKW 394269 2% 71% 12
6 ENDOTHELIN A RECEPTOR authKW 362417 4% 27% 29
7 MOL NEUROBIOL PAIN address 285096 1% 88% 7
8 BMS182874 5 DIMETHYLAMINO N 3 4 DIMETHYL 5 ISOXAZOLYD 1 NAPHTHALENESULFONAMIDE authKW 279279 1% 100% 6
9 ETAR authKW 211564 2% 45% 10
10 ENDOTHELIN 1 authKW 203747 20% 3% 133

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 2305 32% 0% 207
2 Pharmacology & Pharmacy 663 20% 0% 134
3 Medicine, Research & Experimental 386 10% 0% 66
4 Neurosciences 169 12% 0% 77
5 Urology & Nephrology 123 5% 0% 31
6 Anesthesiology 120 3% 0% 19
7 Pathology 88 4% 0% 26
8 Endocrinology & Metabolism 74 5% 0% 35
9 Cell Biology 49 7% 0% 43
10 Clinical Neurology 40 5% 0% 33

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL PATHOL ULTRASTRUCT 1163653 5% 83% 30
2 MOL NEUROBIOL PAIN 285096 1% 88% 7
3 TRANSLAT FUNCT AREA 193942 1% 83% 5
4 BIOENGN NEUROL REHABIL MED 186186 1% 100% 4
5 SENSORY NEUROPHYSIOL 145454 1% 63% 5
6 CANC INFECT DISCOVERY MED 104728 0% 75% 3
7 MOL PATHOL A 104728 0% 75% 3
8 42R 46547 0% 100% 1
9 ANESTHESIOL PERIOPERAT PAIN MEDSTAT SUPPO 46547 0% 100% 1
10 ANESTHESIOLOGIST 46547 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXPERIMENTAL BIOLOGY AND MEDICINE 3456 2% 1% 14
2 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 2613 4% 0% 25
3 JOURNAL OF PAIN 2531 2% 1% 10
4 EUROPEAN UROLOGY SUPPLEMENTS 1976 1% 1% 5
5 INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS 821 1% 0% 4
6 CANCER RESEARCH 769 4% 0% 26
7 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 663 2% 0% 10
8 PAIN 578 2% 0% 10
9 CLINICAL SCIENCE 566 1% 0% 9
10 MOLECULAR CANCER THERAPEUTICS 549 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTHELIN AXIS 523641 2% 75% 15 Search ENDOTHELIN+AXIS Search ENDOTHELIN+AXIS
2 ZIBOTENTAN 455336 2% 65% 15 Search ZIBOTENTAN Search ZIBOTENTAN
3 ATRASENTAN 447666 4% 42% 23 Search ATRASENTAN Search ATRASENTAN
4 ZD4054 394269 2% 71% 12 Search ZD4054 Search ZD4054
5 ENDOTHELIN A RECEPTOR 362417 4% 27% 29 Search ENDOTHELIN+A+RECEPTOR Search ENDOTHELIN+A+RECEPTOR
6 BMS182874 5 DIMETHYLAMINO N 3 4 DIMETHYL 5 ISOXAZOLYD 1 NAPHTHALENESULFONAMIDE 279279 1% 100% 6 Search BMS182874+5+DIMETHYLAMINO+N+3+4+DIMETHYL+5+ISOXAZOLYD+1+NAPHTHALENESULFONAMIDE Search BMS182874+5+DIMETHYLAMINO+N+3+4+DIMETHYL+5+ISOXAZOLYD+1+NAPHTHALENESULFONAMIDE
7 ETAR 211564 2% 45% 10 Search ETAR Search ETAR
8 ENDOTHELIN 1 203747 20% 3% 133 Search ENDOTHELIN+1 Search ENDOTHELIN+1
9 ENDOTHELIN 187756 21% 3% 140 Search ENDOTHELIN Search ENDOTHELIN
10 ENDOTHELIN B RECEPTOR 181645 3% 18% 22 Search ENDOTHELIN+B+RECEPTOR Search ENDOTHELIN+B+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ROSANO, L , SPINELLA, F , BAGNATO, A , (2013) ENDOTHELIN 1 IN CANCER: BIOLOGICAL IMPLICATIONS AND THERAPEUTIC OPPORTUNITIES.NATURE REVIEWS CANCER. VOL. 13. ISSUE 9. P. 637 -651 104 74% 61
2 BAGNATO, A , (2012) THE ENDOTHELIN AXIS AS THERAPEUTIC TARGET IN HUMAN MALIGNANCIES: PRESENT AND FUTURE.CURRENT PHARMACEUTICAL DESIGN. VOL. 18. ISSUE 19. P. 2720-2733 88 68% 5
3 SMITH, TP , HAYMOND, T , SMITH, SN , SWEITZER, SM , (2014) EVIDENCE FOR THE ENDOTHELIN SYSTEM AS AN EMERGING THERAPEUTIC TARGET FOR THE TREATMENT OF CHRONIC PAIN.JOURNAL OF PAIN RESEARCH. VOL. 7. ISSUE . P. 531 -545 80 57% 7
4 BAGNATO, A , LOIZIDOU, M , PFLUG, BR , CURWEN, J , GROWCOTT, J , (2011) ROLE OF THE ENDOTHELIN AXIS AND ITS ANTAGONISTS IN THE TREATMENT OF CANCER.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 163. ISSUE 2. P. 220-233 67 61% 57
5 BAGNATO, A , SPINELLA, F , ROSANO, L , (2008) THE ENDOTHELIN AXIS IN CANCER: THE PROMISE AND THE CHALLENGES OF MOLECULARLY TARGETED THERAPY.CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. VOL. 86. ISSUE 8. P. 473 -484 62 76% 50
6 SAID, N , THEODORESCU, D , (2012) PERMISSIVE ROLE OF ENDOTHELIN RECEPTORS IN TUMOR METASTASIS.LIFE SCIENCES. VOL. 91. ISSUE 13-14. P. 522-527 56 79% 11
7 IRANI, S , SALAJEGHEH, A , SMITH, RA , LAM, AKY , (2014) A REVIEW OF THE PROFILE OF ENDOTHELIN AXIS IN CANCER AND ITS MANAGEMENT.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 89. ISSUE 2. P. 314-321 55 56% 6
8 NELSON, J , BAGNATO, A , BATTISTINI, B , NISEN, P , (2003) THE ENDOTHELIN AXIS: EMERGING ROLE IN CANCER.NATURE REVIEWS CANCER. VOL. 3. ISSUE 2. P. 110-116 42 69% 353
9 SMOLLICH, M , WULFING, P , (2008) TARGETING THE ENDOTHELIN SYSTEM: NOVEL THERAPEUTIC OPTIONS IN GYNECOLOGICAL, UROLOGICAL AND BREAST CANCERS.EXPERT REVIEW OF ANTICANCER THERAPY. VOL. 8. ISSUE 9. P. 1481-1493 67 53% 14
10 BAZAN, V , GEBBIA, N , DI GAUDIO, F , FANALE, D , RIZZO, S , BRONTE, G , RUSSO, A , (2010) ANTI-ENDOTHELIN DRUGS IN SOLID TUMORS.EXPERT OPINION ON EMERGING DRUGS. VOL. 15. ISSUE 1. P. 27 -40 51 64% 9

Classes with closest relation at Level 1


Rank Class id link
1 32051 CD10//CD10 EXPRESSION//BIOPATHOLUMR 599
2 463 ENDOTHELIN//ENDOTHELIN RECEPTORS//SARAFOTOXIN
3 24870 LONGEV SCI//OSTEOBLAST//HOSP GERIATR MED
4 10613 ENDOTHELIN 1//ENDOTHELIN//BQ 123
5 14477 ENDOTHELIN CONVERTING ENZYME//NEPRILYSIN//PHOSPHORAMIDON
6 496 ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS
7 1969 CABAZITAXEL//ABIRATERONE//CASTRATION RESISTANT PROSTATE CANCER
8 26062 LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL
9 35752 CENTHAQUIN//INFRARED SPECTRAL BAND ASSIGNMENTS//2 HYDROXYPENTYLPHOSPHONATES
10 31089 OSTEOBLASTIC METASTASIS//HUMAN BONE MARROW ENDOTHELIAL CELLS//CATTEDRA PATOL GEN

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