Class information for:
Level 1: ENDOTHELIN//ENDOTHELIN RECEPTORS//SARAFOTOXIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
463 3406 32.8 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
668 3       ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
1078 2             ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS 9913
463 1                   ENDOTHELIN//ENDOTHELIN RECEPTORS//SARAFOTOXIN 3406

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOTHELIN authKW 1305200 25% 17% 841
2 ENDOTHELIN RECEPTORS authKW 603683 6% 31% 215
3 SARAFOTOXIN authKW 470950 2% 77% 68
4 ENDOTHELIN 1 authKW 456945 13% 11% 454
5 ETB RECEPTOR authKW 407619 3% 43% 106
6 BQ 123 authKW 378071 3% 38% 111
7 ETA RECEPTOR authKW 317954 3% 38% 94
8 ENDOTHELIN 3 authKW 289977 2% 41% 78
9 ENDOTHELIN RECEPTOR SUBTYPES authKW 196046 1% 63% 35
10 IRL 1620 authKW 190305 1% 56% 38

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 13053 37% 0% 1258
2 Cardiac & Cardiovascular System 2460 12% 0% 397
3 Physiology 2017 9% 0% 315
4 Endocrinology & Metabolism 1725 10% 0% 333
5 Biophysics 1233 8% 0% 269
6 Biochemistry & Molecular Biology 1108 19% 0% 644
7 Neurosciences 673 11% 0% 363
8 Chemistry, Medicinal 551 5% 0% 154
9 Medicine, Research & Experimental 477 6% 0% 190
10 Peripheral Vascular Diseases 438 4% 0% 139

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CATEDRA FISIOPATOL 16624 0% 14% 13
2 DIGEST SCI 13032 0% 36% 4
3 DRUG DISCOVERY CHEM PRECLIN 11950 0% 67% 2
4 MARY KAY ASH CANC 11950 0% 67% 2
5 METAB DIS DRUG ANAL 11950 0% 67% 2
6 PARKE DAVIS PHARMACEUT PHARMACOL 11521 0% 43% 3
7 A FIORINI HOSP TERRACINA LT 8963 0% 100% 1
8 ABT NMR UNTERSTUTZTE STRUKTURBIOL 8963 0% 100% 1
9 ABT PEPTIDCHEM 8963 0% 100% 1
10 AGING DEV BIOL NEUROVASC BIOL 8963 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 92533 10% 3% 337
2 BRITISH JOURNAL OF PHARMACOLOGY 10594 4% 1% 146
3 EUROPEAN JOURNAL OF PHARMACOLOGY 9010 5% 1% 170
4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 3920 5% 0% 177
5 LIFE SCIENCES 2788 2% 0% 81
6 REGULATORY PEPTIDES 2677 1% 1% 38
7 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2597 2% 0% 80
8 EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION 2115 0% 1% 16
9 RECEPTORS & SIGNAL TRANSDUCTION 2011 0% 8% 3
10 AMERICAN JOURNAL OF PHYSIOLOGY 1920 2% 0% 75

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENDOTHELIN 1305200 25% 17% 841 Search ENDOTHELIN Search ENDOTHELIN
2 ENDOTHELIN RECEPTORS 603683 6% 31% 215 Search ENDOTHELIN+RECEPTORS Search ENDOTHELIN+RECEPTORS
3 SARAFOTOXIN 470950 2% 77% 68 Search SARAFOTOXIN Search SARAFOTOXIN
4 ENDOTHELIN 1 456945 13% 11% 454 Search ENDOTHELIN+1 Search ENDOTHELIN+1
5 ETB RECEPTOR 407619 3% 43% 106 Search ETB+RECEPTOR Search ETB+RECEPTOR
6 BQ 123 378071 3% 38% 111 Search BQ+123 Search BQ+123
7 ETA RECEPTOR 317954 3% 38% 94 Search ETA+RECEPTOR Search ETA+RECEPTOR
8 ENDOTHELIN 3 289977 2% 41% 78 Search ENDOTHELIN+3 Search ENDOTHELIN+3
9 ENDOTHELIN RECEPTOR SUBTYPES 196046 1% 63% 35 Search ENDOTHELIN+RECEPTOR+SUBTYPES Search ENDOTHELIN+RECEPTOR+SUBTYPES
10 IRL 1620 190305 1% 56% 38 Search IRL+1620 Search IRL+1620

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RUBANYI, GM , POLOKOFF, MA , (1994) ENDOTHELINS - MOLECULAR-BIOLOGY, BIOCHEMISTRY, PHARMACOLOGY, PHYSIOLOGY, AND PATHOPHYSIOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 46. ISSUE 3. P. 325 -415 479 50% 1468
2 KUWAKI, T , KURIHARA, H , CAO, WH , KURIHARA, Y , UNEKAWA, M , YAZAKI, Y , KUMADA, M , (1997) PHYSIOLOGICAL ROLE OF BRAIN ENDOTHELIN IN THE CENTRAL AUTONOMIC CONTROL: FROM NEURON TO KNOCKOUT MOUSE.PROGRESS IN NEUROBIOLOGY. VOL. 51. ISSUE 5. P. 545 -579 202 72% 80
3 HUGGINS, JP , PELTON, JT , MILLER, RC , (1993) THE STRUCTURE AND SPECIFICITY OF ENDOTHELIN RECEPTORS - THEIR IMPORTANCE IN PHYSIOLOGY AND MEDICINE.PHARMACOLOGY & THERAPEUTICS. VOL. 59. ISSUE 1. P. 55-123 235 60% 173
4 VAN DEN BUUSE, M , WEBBER, KM , (2000) ENDOTHELIN AND DOPAMINE RELEASE.PROGRESS IN NEUROBIOLOGY. VOL. 60. ISSUE 4. P. 385 -405 159 80% 45
5 IQBAL, J , SANGHI, R , DAS, SK , (2005) ENDOTHELIN RECEPTOR ANTAGONISTS: AN OVERVIEW OF THEIR SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 5. ISSUE 4. P. 381-408 102 80% 14
6 RAE, GA , CALIXTO, JB , DORLEANSJUSTE, P , (1995) EFFECTS AND MECHANISMS OF ACTION OF ENDOTHELINS ON NONVASCULAR SMOOTH-MUSCLE OF THE RESPIRATORY, GASTROINTESTINAL AND UROGENITAL TRACTS.REGULATORY PEPTIDES. VOL. 55. ISSUE 1. P. 1-46 196 57% 25
7 SCHINELLI, S , (2006) PHARMACOLOGY AND PHYSIOPATHOLOGY OF THE BRAIN ENDOTHELIN SYSTEM: AN OVERVIEW.CURRENT MEDICINAL CHEMISTRY. VOL. 13. ISSUE 6. P. 627-638 112 62% 49
8 GULATI, A , SRIMAL, RC , (1992) ENDOTHELIN MECHANISMS IN THE CENTRAL-NERVOUS-SYSTEM - A TARGET FOR DRUG DEVELOPMENT.DRUG DEVELOPMENT RESEARCH. VOL. 26. ISSUE 4. P. 361 -387 140 79% 42
9 STOJILKOVIC, SS , CATT, KJ , (1996) EXPRESSION AND SIGNAL TRANSDUCTION PATHWAYS OF ENDOTHELIN RECEPTORS IN NEUROENDOCRINE CELLS.FRONTIERS IN NEUROENDOCRINOLOGY. VOL. 17. ISSUE 3. P. 327-369 135 66% 57
10 WEBB, ML , MEEK, TD , (1997) INHIBITORS OF ENDOTHELIN.MEDICINAL RESEARCH REVIEWS. VOL. 17. ISSUE 1. P. 17 -67 145 58% 67

Classes with closest relation at Level 1


Rank Class id link
1 10613 ENDOTHELIN 1//ENDOTHELIN//BQ 123
2 496 ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS
3 16384 MOL PATHOL ULTRASTRUCT//ENDOTHELIN AXIS//ZIBOTENTAN
4 14477 ENDOTHELIN CONVERTING ENZYME//NEPRILYSIN//PHOSPHORAMIDON
5 27763 EXPT VASC//WNC//CLIN EXPT
6 24870 LONGEV SCI//OSTEOBLAST//HOSP GERIATR MED
7 36439 CIHR GRP IMMUNOCARDIOVASC INTERACT//R TYPE CA2 CHANNEL//ENDOCARDIAL ENDOTHELIAL CELLS
8 26062 LOE 908//G ALPHA12//VOLTAGE INDEPENDENT CALCIUM CHANNEL
9 6547 PORTAL HYPERTENSION//HEPAT HEMODYNAM//HYPERDYNAMIC CIRCULATION
10 3828 ENDOTHELIUM DERIVED RELAXING FACTOR//EDRF//N G NITRO L ARGININE

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