Class information for:
Level 1: SABARUBICIN//BARMINOMYCIN//ACTINOMYCIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9157 1182 33.8 53%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
1654 2             DISTAMYCIN//MINOR GROOVE BINDER//PYRROLE IMIDAZOLE POLYAMIDE 6885
9157 1                   SABARUBICIN//BARMINOMYCIN//ACTINOMYCIN 1182

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SABARUBICIN authKW 183693 1% 89% 8
2 BARMINOMYCIN authKW 103328 0% 100% 4
3 ACTINOMYCIN authKW 82350 1% 25% 13
4 DAUNOMYCIN authKW 81788 2% 14% 23
5 DOXOFORM authKW 77496 0% 100% 3
6 FORMALDEHYDE ACTIVATION authKW 58121 0% 75% 3
7 STUDIA BIOPHYSICA journal 55741 5% 3% 64
8 ANTHRACYCLINE DISACCHARIDES authKW 51664 0% 100% 2
9 FORMALDEHYDE RELEASING PRODRUGS authKW 51664 0% 100% 2
10 METAL ACRIDINES authKW 51664 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biophysics 4889 24% 0% 281
2 Biochemistry & Molecular Biology 4194 50% 0% 588
3 Chemistry, Medicinal 783 8% 0% 98
4 Pharmacology & Pharmacy 296 12% 0% 138
5 Chemistry, Multidisciplinary 187 11% 0% 131
6 Chemistry, Physical 112 10% 0% 115
7 Chemistry, Organic 83 5% 0% 65
8 Biochemical Research Methods 61 3% 0% 40
9 Oncology 60 6% 0% 70
10 Spectroscopy 54 3% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOL CHEM CORE TECHNOL 51664 0% 100% 2
2 AEG CREA 25832 0% 100% 1
3 BERBECK 25832 0% 100% 1
4 BIOMOLEC STRUCT UNIT CANC CAMPAIGN 25832 0% 100% 1
5 BIOORGAN UNIT 25832 0% 100% 1
6 BIOSECIENCES BIOMED ENGN 25832 0% 100% 1
7 CINESE SCI 25832 0% 100% 1
8 CLAUDE FREJACQUESDSMDRECAMSCM 25832 0% 100% 1
9 CLIN STUDY ANTICANCER MOL TARGETED DRUGS 25832 0% 100% 1
10 IND ENVIRONM BIOTECHNOL GRP 25832 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STUDIA BIOPHYSICA 55741 5% 3% 64
2 BIOPOLYMERS 15732 5% 1% 63
3 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 14490 4% 1% 42
4 ANTI-CANCER DRUG DESIGN 11874 1% 3% 17
5 BIOCHEMISTRY 5448 9% 0% 107
6 NUCLEIC ACIDS RESEARCH 2677 5% 0% 65
7 MOLECULAR BIOLOGY 1957 2% 0% 19
8 BIOFIZIKA 1758 1% 0% 17
9 ADVANCES IN PHARMACOLOGY AND CHEMOTHERAPY 1433 0% 6% 1
10 BIOPHYSICAL CHEMISTRY 1346 1% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SABARUBICIN 183693 1% 89% 8 Search SABARUBICIN Search SABARUBICIN
2 BARMINOMYCIN 103328 0% 100% 4 Search BARMINOMYCIN Search BARMINOMYCIN
3 ACTINOMYCIN 82350 1% 25% 13 Search ACTINOMYCIN Search ACTINOMYCIN
4 DAUNOMYCIN 81788 2% 14% 23 Search DAUNOMYCIN Search DAUNOMYCIN
5 DOXOFORM 77496 0% 100% 3 Search DOXOFORM Search DOXOFORM
6 FORMALDEHYDE ACTIVATION 58121 0% 75% 3 Search FORMALDEHYDE+ACTIVATION Search FORMALDEHYDE+ACTIVATION
7 ANTHRACYCLINE DISACCHARIDES 51664 0% 100% 2 Search ANTHRACYCLINE+DISACCHARIDES Search ANTHRACYCLINE+DISACCHARIDES
8 FORMALDEHYDE RELEASING PRODRUGS 51664 0% 100% 2 Search FORMALDEHYDE+RELEASING+PRODRUGS Search FORMALDEHYDE+RELEASING+PRODRUGS
9 METAL ACRIDINES 51664 0% 100% 2 Search METAL+ACRIDINES Search METAL+ACRIDINES
10 RESTRICTION INHIBITION ASSAY RIA 51664 0% 100% 2 Search RESTRICTION+INHIBITION+ASSAY+RIA Search RESTRICTION+INHIBITION+ASSAY+RIA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KIMURA, K , SPENCER, DMS , BILARDI, R , SWIFT, LP , BOX, AJ , BROWNLEE, RTC , CUTTS, SM , PHILLIPS, DR , (2010) BARMINOMYCIN, A MODEL FOR THE DEVELOPMENT OF NEW ANTHRACYCLINES.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 1. P. 70-77 35 85% 1
2 BARTHWAL, R , SHARMA, U , SNIVASTAVA, N , JAIN, M , AWASTHI, P , KAUR, M , BARTHWAL, SK , GOVIL, G , (2006) STRUCTURE OF DAUNOMYCIN COMPLEXED TO D-TGATCA BY TWO-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 41. ISSUE 1. P. 27-39 33 85% 6
3 CUTTS, SM , REPHAELI, A , NUDELMAN, A , UGARENKO, M , PHILLIPS, DR , (2015) POTENTIAL THERAPEUTIC ADVANTAGES OF DOXORUBICIN WHEN ACTIVATED BY FORMALDEHYDE TO FUNCTION AS A DNA ADDUCT-FORMING AGENT.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 14. P. 1409 -1422 45 49% 0
4 AGRAWAL, P , BARTHWAL, SK , GOVIL, G , BARTHWAL, R , (2009) STUDIES ON THE INTERACTION OF ADRIAMYCIN WITH D-(TGATCA)(2) BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, TIME-RESOLVED FLUORESCENCE MEASUREMENT, DIFFUSION ORDERED SPECTROSCOPY FOLLOWED BY STRUCTURAL REFINEMENT USING RESTRAINED MOLECULAR DYNAMICS APPROACH.JOURNAL OF MOLECULAR STRUCTURE. VOL. 932. ISSUE 1-3. P. 67-83 26 81% 1
5 CUTTS, SM , NUDELMAN, A , REPHAELI, A , PHILLIPS, DR , (2005) THE POWER AND POTENTIAL OF DOXORUBICIN-DNA ADDUCTS.IUBMB LIFE. VOL. 57. ISSUE 2. P. 73 -81 29 67% 72
6 BIVER, T , VENTURINI, M , JARES-ERIJMAN, EA , JOVIN, TM , SECCO, F , (2009) 7-AMINOACTINOMYCIN BINDING TO DNA SEQUENCES LACKING GPC SITES: A THERMODYNAMIC AND KINETIC STUDY.BIOCHEMISTRY. VOL. 48. ISSUE 1. P. 173-179 22 88% 3
7 DOUGHTY, B , RAO, Y , KAZER, SW , KWOK, SJJ , TURRO, NJ , EISENTHAL, KB , (2013) BINDING OF THE ANTI-CANCER DRUG DAUNOMYCIN TO DNA PROBED BY SECOND HARMONIC GENERATION.JOURNAL OF PHYSICAL CHEMISTRY B. VOL. 117. ISSUE 49. P. 15285-15289 31 53% 10
8 AGRAWAL, P , BARTHWAL, SK , GOVIL, G , BARTHWAL, R , (2009) SOLUTION STUDIES ON THE COMPLEX OF 4 '-EPIADRIAMYCIN-D-(CGATCG)(2) FOLLOWED BY TIME-RESOLVED FLUORESCENCE MEASUREMENT, DIFFUSION ORDERED SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS SIMULATIONS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 17. ISSUE 7. P. 2793-2811 24 75% 0
9 MUKHERJEE, A , SASIKALA, WD , (2013) DRUG-DNA INTERCALATION: FROM DISCOVERY TO THE MOLECULAR MECHANISM.DYNAMICS OF PROTEINS AND NUCLEIC ACIDS. VOL. 92. ISSUE . P. 1 -62 40 35% 14
10 ZHU, SH , YAN, LM , JI, XB , LU, WC , (2010) CONFORMATIONAL DIVERSITY OF ANTHRACYCLINE ANTICANCER ANTIBIOTICS: A DENSITY FUNCTIONAL THEORY CALCULATION.JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM. VOL. 951. ISSUE 1-3. P. 60 -68 34 47% 3

Classes with closest relation at Level 1


Rank Class id link
1 19395 ECHINOMYCIN//STREPTOMYCES ALBOFLAVUS 313//PIPERAZIC ACID
2 36153 ACTINOCIN//A2780 HUMAN OVARIAN CANCER//ACTINOCINE MONOAMIDES
3 21187 HETERO ASSOCIATION//NOVATRONE//STACKING COMPLEXES
4 15583 METHOXYMORPHOLINO DOXORUBICIN//AD 198//MORPHOLINYLANTHRACYCLINES
5 3208 MINOR GROOVE BINDER//DISTAMYCIN//PYRROLE IMIDAZOLE POLYAMIDE
6 27930 FLUOROVISUALIZATION//FLASH WAVE LIGHT//MOUSE OSTEOSARCOMA
7 28228 METAL COMPLEXES OF NUCLEIC ACIDS//ISING PROBLEM//INTERACTION OF LIGANDS WITH DNA
8 34581 MENOGARIL//DNA UNWINDING ACTIVITY//N O O TRIANGULAR PHARMACOPHORE
9 10232 MITOXANTRONE//PIXANTRONE//PIROXANTRONE
10 7272 ACRIDINE//C 1311//PYRAZOLOACRIDINE

Go to start page