Class information for:
Level 1: METHOXYMORPHOLINO DOXORUBICIN//AD 198//MORPHOLINYLANTHRACYCLINES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15583 703 25.0 49%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
346 3       CARDIOTOXICITY//ANTHRACYCLINES//CAMPTOTHECIN 36072
2252 2             ANGUCYCLINE//IDARUBICIN//ANGUCYCLINONE 4694
15583 1                   METHOXYMORPHOLINO DOXORUBICIN//AD 198//MORPHOLINYLANTHRACYCLINES 703

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METHOXYMORPHOLINO DOXORUBICIN authKW 260607 1% 100% 6
2 AD 198 authKW 212825 1% 70% 7
3 MORPHOLINYLANTHRACYCLINES authKW 130303 0% 100% 3
4 RHODOMYCIN authKW 130303 0% 100% 3
5 STREPTOMYCES PURPURASCENS authKW 130303 0% 100% 3
6 ANNAMYCIN authKW 115823 1% 67% 4
7 AKLAVINONE authKW 97726 0% 75% 3
8 11 HYDROXYACLACINOMYCIN X ID 6105 authKW 86869 0% 100% 2
9 ANTHRACYCLINE ANALOGS authKW 86869 0% 100% 2
10 BIOACT MOLEC SHINJUKU KU address 86869 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 2793 38% 0% 264
2 Oncology 2261 30% 0% 213
3 Microbiology 1994 23% 0% 162
4 Biotechnology & Applied Microbiology 1284 19% 0% 134
5 Immunology 591 15% 0% 108
6 Chemistry, Medicinal 361 7% 0% 52
7 Chemistry, Organic 121 8% 0% 53
8 Biochemistry & Molecular Biology 30 10% 0% 73
9 Hematology 19 2% 0% 17
10 Chemistry, Applied 8 2% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOACT MOLEC SHINJUKU KU 86869 0% 100% 2
2 MD ANDERSON CANC CLIN INVEST 48860 0% 38% 3
3 CELLULAIRE MOL PHARMACOL 43434 0% 100% 1
4 HIGH MOL WEIGHT COMPOUNDS 43434 0% 100% 1
5 MD ANDERSON CANC VET MED 43434 0% 100% 1
6 MED PHARMACOL VIA ROME 55 43434 0% 100% 1
7 ONCOL ASTURIAS PRINCIPATE IUOPA 43434 0% 100% 1
8 SCI BIOL YUSUNG GU 43434 0% 100% 1
9 UT CANC 43432 0% 50% 2
10 CBITRCBIOTECHNOL 21716 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ANTIBIOTICS 62782 14% 1% 98
2 ANTIBIOTIKI 38872 3% 5% 19
3 CANCER TREATMENT REPORTS 7858 3% 1% 20
4 CANCER CHEMOTHERAPY AND PHARMACOLOGY 7638 5% 0% 36
5 ANTIBIOTIKI I MEDITSINSKAYA BIOTEKHNOLOGIYA 5500 1% 2% 7
6 CANADIAN JOURNAL OF MEDICAL TECHNOLOGY 2713 0% 6% 1
7 ANTIBIOTIKI I KHIMIOTERAPIYA 2656 1% 1% 6
8 RECENT RESULTS IN CANCER RESEARCH 2062 1% 1% 5
9 ZEITSCHRIFT FUR ALLGEMEINE MIKROBIOLOGIE 1855 1% 1% 4
10 JOURNAL OF BASIC MICROBIOLOGY 1834 1% 0% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METHOXYMORPHOLINO DOXORUBICIN 260607 1% 100% 6 Search METHOXYMORPHOLINO+DOXORUBICIN Search METHOXYMORPHOLINO+DOXORUBICIN
2 AD 198 212825 1% 70% 7 Search AD+198 Search AD+198
3 MORPHOLINYLANTHRACYCLINES 130303 0% 100% 3 Search MORPHOLINYLANTHRACYCLINES Search MORPHOLINYLANTHRACYCLINES
4 RHODOMYCIN 130303 0% 100% 3 Search RHODOMYCIN Search RHODOMYCIN
5 STREPTOMYCES PURPURASCENS 130303 0% 100% 3 Search STREPTOMYCES+PURPURASCENS Search STREPTOMYCES+PURPURASCENS
6 ANNAMYCIN 115823 1% 67% 4 Search ANNAMYCIN Search ANNAMYCIN
7 AKLAVINONE 97726 0% 75% 3 Search AKLAVINONE Search AKLAVINONE
8 11 HYDROXYACLACINOMYCIN X ID 6105 86869 0% 100% 2 Search 11+HYDROXYACLACINOMYCIN+X+ID+6105 Search 11+HYDROXYACLACINOMYCIN+X+ID+6105
9 ANTHRACYCLINE ANALOGS 86869 0% 100% 2 Search ANTHRACYCLINE+ANALOGS Search ANTHRACYCLINE+ANALOGS
10 HYRUBICIN 86869 0% 100% 2 Search HYRUBICIN Search HYRUBICIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LAATSCH, H , FOTSO, S , (2008) NATURALLY OCCURRING ANTHRACYCLINES.ANTHRACYCLINE CHEMISTRY AND BIOLOGY I: BIOLOGICAL OCCURENCE AND BIOSYNTHESIS, SYNTHESIS AND CHEMISTRY. VOL. 282. ISSUE . P. 3 -74 64 58% 10
2 ARCAMONE, F , CASSINELLI, G , (1998) BIOSYNTHETIC ANTHRACYCLINES.CURRENT MEDICINAL CHEMISTRY. VOL. 5. ISSUE 5. P. 391 -419 66 72% 41
3 BROGGINI, M , (2008) NEMORUBICIN.ANTHRACYCLINE CHEMISTRY AND BIOLOGY II: MODE OF ACTION, CLINICAL ASPECTS AND NEW DRUGS. VOL. 283. ISSUE . P. 191 -206 21 88% 2
4 NIEMI, J , METSA-KETELA, M , SCHNEIDER, G , MANTSALA, P , (2008) BIOSYNTHETIC ANTHRACYCLINE VARIANTS.ANTHRACYCLINE CHEMISTRY AND BIOLOGY I: BIOLOGICAL OCCURENCE AND BIOSYNTHESIS, SYNTHESIS AND CHEMISTRY. VOL. 282. ISSUE . P. 75 -99 27 49% 1
5 LU, H , WAXMAN, DJ , (2005) ANTITUMOR ACTIVITY OF METHOXYMORPHOLINYL DOXORUBICIN: POTENTIATION BY CYTOCHROME P450 3A METABOLISM.MOLECULAR PHARMACOLOGY. VOL. 67. ISSUE 1. P. 212-219 22 59% 16
6 STRAUSS, DG , (1987) STRUCTURES OF ANTHRACYCLINE ANTITUMOR AGENTS.PHARMAZIE. VOL. 42. ISSUE 5. P. 289-303 49 52% 9
7 YOSHIMOTO, A , NAKAMURA, T , KUBO, K , JOHDO, O , TONE, H , (1995) DAUNOMYCIN BIOSYNTHESIS BY MICROBIAL CONVERSION OF PRECURSOR METABOLITES USING BIOSYNTHETICALLY BLOCKED MUTANTS.JOURNAL OF FERMENTATION AND BIOENGINEERING. VOL. 79. ISSUE 3. P. 229 -235 18 95% 3
8 WAGNER, C , ECKARDT, K , IHN, W , SCHUMANN, G , STENGEL, C , FLECK, WF , TRESSELT, D , (1991) BIOSYNTHESIS OF ANTHRACYCLINES - DISCUSSION OF THE RESULTS ON DAUNOMYCIN BIOSYNTHESIS FROM A NEW POINT-OF-VIEW.JOURNAL OF BASIC MICROBIOLOGY. VOL. 31. ISSUE 3. P. 223-240 22 85% 6
9 BEGLEITER, A , LEITH, MK , JOHNSTON, JB , (1994) ACTIVITY OF 3'-(3-CYANO-4-MORPHOLINYL)-3'DEAMINOADRIAMYCIN IN SENSITIVE AND RESISTANT L5178Y LYMPHOBLASTS IN-VITRO.CANCER RESEARCH. VOL. 54. ISSUE 2. P. 482-486 23 64% 4
10 OLSUFYEVA, EN , (1992) SYNTHESIS AND ANTITUMOR-ACTIVITY OF NEW DERIVATIVES OF ANTHRACYCLINE ANTIBIOTICS MODIFIED IN THE SUGAR MOIETY.BIOORGANICHESKAYA KHIMIYA. VOL. 18. ISSUE 2. P. 149-181 26 60% 2

Classes with closest relation at Level 1


Rank Class id link
1 11318 ANTHRACYCLINONES//441 NISHI OHNUMA//NISHI OHNUMA
2 8111 IDARUBICIN//IDARUBICINOL//MODIFIED ANTIBIOT
3 34581 MENOGARIL//DNA UNWINDING ACTIVITY//N O O TRIANGULAR PHARMACOPHORE
4 9157 SABARUBICIN//BARMINOMYCIN//ACTINOMYCIN
5 29160 PLURAMYCINS//HEDAMYCIN//ANTHRAPYRAN ANTIBIOTICS
6 26690 STREPTAZOLIN//AZALOMYCIN F 5A//CHIRAL NMR SOLVENT
7 11917 2 DEOXYGLYCOSIDES//VANCOSAMINE//2 6 ANHYDRO 2 THIO SUGAR
8 35981 ACID INDUCED INDOLE CYCLIZATION//22810 TAMAGAWA SETAGAYA KU//1 1 7 7 TETRAMETHOXY 4 HEPTANONE DERIVATIVE
9 33598 IMEXON//CYANOAZIRIDINE//AZIRIDINE 2 CARBOXAMIDE
10 1652 DOXORUBICIN//CARDIOTOXICITY//DEXRAZOXANE

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