Class information for:
Level 1: ARYLAMINE N ACETYLTRANSFERASE//NAT2//N ACETYLTRANSFERASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6238 1509 37.3 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
1239 2             HETEROCYCLIC AMINES//HETEROCYCLIC AROMATIC AMINES//PHIP 9032
6238 1                   ARYLAMINE N ACETYLTRANSFERASE//NAT2//N ACETYLTRANSFERASE 1509

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARYLAMINE N ACETYLTRANSFERASE authKW 1605497 6% 85% 93
2 NAT2 authKW 1550035 9% 58% 131
3 N ACETYLTRANSFERASE authKW 1473181 11% 44% 167
4 N ACETYLTRANSFERASE 2 authKW 918855 5% 64% 71
5 2 AMINOFLUORENE authKW 621025 4% 57% 54
6 NAT1 authKW 469465 2% 63% 37
7 N ACETYL 2 AMINOFLUORENE authKW 345038 1% 95% 18
8 ACETYLATION POLYMORPHISM authKW 332013 1% 86% 19
9 N ACETYLTRANSFERASE 1 authKW 304342 1% 79% 19
10 ACETYLATOR PHENOTYPE authKW 288019 1% 65% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 5139 35% 0% 528
2 Toxicology 1989 11% 0% 173
3 Oncology 1547 18% 0% 274
4 Genetics & Heredity 490 9% 0% 133
5 Biochemistry & Molecular Biology 263 15% 0% 231
6 Public, Environmental & Occupational Health 118 5% 0% 76
7 Medicine, Research & Experimental 71 4% 0% 57
8 Medical Laboratory Technology 55 1% 0% 19
9 Rheumatology 35 1% 0% 18
10 Chemistry, Medicinal 33 2% 0% 33

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EA 1553 101169 0% 100% 5
2 UMR7000 60701 0% 100% 3
3 UFR BIOCHIM 48928 1% 16% 15
4 ENVIRONM GENOM INTEGRAT BIOL 39229 1% 24% 8
5 UNITE BIOL FONCT AD TAT 28764 1% 18% 8
6 MED TECHNOL OPTOMETRY 26977 0% 67% 2
7 POST BIOTECHNOL PROGRAM 26977 0% 67% 2
8 REPONSES MOL CELLULAI XENOBIOT 26977 0% 67% 2
9 UMR 7000 25593 1% 14% 9
10 JAMES GRAHAM BROWN CANC 22129 3% 3% 39

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOGENETICS 123533 5% 8% 76
2 CARCINOGENESIS 7069 4% 1% 64
3 DRUG METABOLISM AND DISPOSITION 5640 3% 1% 46
4 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 4115 2% 1% 36
5 PHARMACOGENETICS AND GENOMICS 2992 1% 1% 13
6 PHARMACOGENOMICS 2897 1% 1% 16
7 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2703 2% 0% 31
8 CURRENT DRUG METABOLISM 2640 1% 1% 12
9 CLINICAL PHARMACOLOGY & THERAPEUTICS 1962 2% 0% 24
10 BIOCHEMICAL PHARMACOLOGY 1605 3% 0% 39

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ARYLAMINE N ACETYLTRANSFERASE 1605497 6% 85% 93 Search ARYLAMINE+N+ACETYLTRANSFERASE Search ARYLAMINE+N+ACETYLTRANSFERASE
2 NAT2 1550035 9% 58% 131 Search NAT2 Search NAT2
3 N ACETYLTRANSFERASE 1473181 11% 44% 167 Search N+ACETYLTRANSFERASE Search N+ACETYLTRANSFERASE
4 N ACETYLTRANSFERASE 2 918855 5% 64% 71 Search N+ACETYLTRANSFERASE+2 Search N+ACETYLTRANSFERASE+2
5 2 AMINOFLUORENE 621025 4% 57% 54 Search 2+AMINOFLUORENE Search 2+AMINOFLUORENE
6 NAT1 469465 2% 63% 37 Search NAT1 Search NAT1
7 N ACETYL 2 AMINOFLUORENE 345038 1% 95% 18 Search N+ACETYL+2+AMINOFLUORENE Search N+ACETYL+2+AMINOFLUORENE
8 ACETYLATION POLYMORPHISM 332013 1% 86% 19 Search ACETYLATION+POLYMORPHISM Search ACETYLATION+POLYMORPHISM
9 N ACETYLTRANSFERASE 1 304342 1% 79% 19 Search N+ACETYLTRANSFERASE+1 Search N+ACETYLTRANSFERASE+1
10 ACETYLATOR PHENOTYPE 288019 1% 65% 22 Search ACETYLATOR+PHENOTYPE Search ACETYLATOR+PHENOTYPE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BOUKOUVALA, S , FAKIS, G , (2005) ARYLAMINE N-ACETYLTRANSFERASES: WHAT WE LEARN FROM GENES AND GENOMES.DRUG METABOLISM REVIEWS. VOL. 37. ISSUE 3. P. 511 -564 253 81% 78
2 SIM, E , ABUHAMMAD, A , RYAN, A , (2014) ARYLAMINE N-ACETYLTRANSFERASES: FROM DRUG METABOLISM AND PHARMACOGENETICS TO DRUG DISCOVERY.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 171. ISSUE 11. P. 2705 -2725 158 84% 20
3 HEIN, DW , DOLL, MA , FRETLAND, AJ , LEFF, MA , WEBB, SJ , XIAO, GH , DEVANOBOYINA, US , NANGJU, NA , FENG, Y , (2000) MOLECULAR GENETICS AND EPIDEMIOLOGY OF THE NAT1 AND NAT2 ACETYLATION POLYMORPHISMS.CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. VOL. 9. ISSUE 1. P. 29 -42 149 86% 437
4 SIM, E , LACK, N , WANG, CJ , LONG, H , WESTWOOD, I , FULLAM, E , KAWAMURA, A , (2008) ARYLAMINE N-ACETYLTRANSFERASES: STRUCTURAL AND FUNCTIONAL IMPLICATIONS OF POLYMORPHISMS.TOXICOLOGY. VOL. 254. ISSUE 3. P. 170-183 119 94% 62
5 HEIN, DW , (2006) N-ACETYLTRANSFERASE 2 GENETIC POLYMORPHISM: EFFECTS OF CARCINOGEN AND HAPLOTYPE ON URINARY BLADDER CANCER RISK.ONCOGENE. VOL. 25. ISSUE 11. P. 1649-1658 108 86% 117
6 SIM, E , WESTWOOD, I , FULLAM, E , (2007) ARYLAMINE N-ACETYLTRANSFERASES.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 3. ISSUE 2. P. 169-184 106 84% 35
7 BUTCHER, NJ , MINCHIN, RF , (2012) ARYLAMINE N-ACETYLTRANSFERASE 1: A NOVEL DRUG TARGET IN CANCER DEVELOPMENT.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 1. P. 147 -165 132 57% 23
8 AGUNDEZ, JAG , (2008) POLYMORPHISMS OF HUMAN N-ACETYLTRANSFERASES AND CANCER RISK.CURRENT DRUG METABOLISM. VOL. 9. ISSUE 6. P. 520 -531 134 57% 75
9 WALKER, K , GINSBERG, G , HATTIS, D , JOHNS, DO , GUYTON, KZ , SONAWANE, B , (2009) GENETIC POLYMORPHISM IN N-ACETYLTRANSFERASE (NAT): POPULATION DISTRIBUTION OF NAT1 AND NAT2 ACTIVITY.JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS. VOL. 12. ISSUE 5-6. P. 440 -472 93 79% 45
10 FAKIS, G , BOUKOUVALA, S , VAGENA, E , (2008) ARYLAMINE N-ACETYLTRANSFERASES IN PROKARYOTIC AND EUKARYOTIC GENOMES: A SURVEY OF PUBLIC DATABASES.CURRENT DRUG METABOLISM. VOL. 9. ISSUE 7. P. 628 -660 129 62% 7

Classes with closest relation at Level 1


Rank Class id link
1 16470 ISONIAZID//ANTITUBERCULOSIS DRUG INDUCED HEPATOTOXICITY//DRUG REASSESSMENT
2 1419 GSTM1//GSTT1//GSTP1
3 13167 FLORIDA TOXICOL//3 3 DICHLOROBENZIDINE//N 2 METHOXYPHENYLHYDROXYLAMINE
4 2424 HETEROCYCLIC AMINES//HETEROCYCLIC AROMATIC AMINES//PHIP
5 10694 CYP1A2//CAFFEINE//CAFFEINE METABOLISM
6 15918 DIHYDRALAZINE SULFATE//DRUG INDUCED LUPUS//HYDRALAZINE HYDROCHLORIDE
7 25968 HUMAN S9//1 1 DIBROMOBENZENE//1 METHYL 2 ARYLETHYL HYDROXYLAMINE
8 28360 LOBUND//3 2 DIMETHYL 4 AMINOBIPHENYL//PROSTATE SEMINAL VESICLE CANCER
9 5782 DNA ADDUCTS//I COMPOUNDS//P 32 POSTLABELING
10 20908 N 2 ACETYLAMINOFLUORENE//AMINOFLUORENE//ACETYLAMINOFLUORENE

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