Class information for:
Level 1: FLORIDA TOXICOL//3 3 DICHLOROBENZIDINE//N 2 METHOXYPHENYLHYDROXYLAMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13167 856 35.3 48%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
1239 2             HETEROCYCLIC AMINES//HETEROCYCLIC AROMATIC AMINES//PHIP 9032
13167 1                   FLORIDA TOXICOL//3 3 DICHLOROBENZIDINE//N 2 METHOXYPHENYLHYDROXYLAMINE 856

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FLORIDA TOXICOL address 411257 2% 82% 14
2 3 3 DICHLOROBENZIDINE authKW 116517 1% 47% 7
3 N 2 METHOXYPHENYLHYDROXYLAMINE authKW 107012 0% 100% 3
4 N ACETYLBENZIDINE authKW 107012 0% 100% 3
5 XENOBIOTIC OXIDATION authKW 107012 0% 100% 3
6 BENZIDINE authKW 99051 2% 14% 20
7 HYDROPEROXIDASE authKW 97095 1% 39% 7
8 C NITROSO AROMATICS authKW 71341 0% 100% 2
9 CO OXIDASE authKW 71341 0% 100% 2
10 FREE RADICALS OF PHENOTHIAZINES authKW 71341 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 11715 35% 0% 300
2 Oncology 1369 22% 0% 189
3 Pharmacology & Pharmacy 1250 24% 0% 205
4 Biochemistry & Molecular Biology 330 20% 0% 172
5 Biophysics 156 6% 0% 51
6 Genetics & Heredity 124 6% 0% 55
7 Chemistry, Medicinal 124 4% 0% 37
8 Environmental Sciences 92 7% 0% 59
9 Public, Environmental & Occupational Health 81 5% 0% 46
10 Chemistry, Multidisciplinary 54 8% 0% 71

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FLORIDA TOXICOL 411257 2% 82% 14
2 PULM FUNCT TOXICOL 53503 0% 50% 3
3 13201 BRUCE B DOWNS BLVD 35671 0% 100% 1
4 BIOCHEM BIOL A 35671 0% 100% 1
5 CONTROL EFFECT EVALUAT 35671 0% 100% 1
6 GERIATR MED BIOCHEM 35671 0% 100% 1
7 GRECC11GJB 35671 0% 100% 1
8 KATZ GRP PHARM HLTH 2 043 35671 0% 100% 1
9 MICROBIOL MOL SCI 35671 0% 100% 1
10 NOVA NEMOCNI 35671 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS 27181 11% 1% 94
2 CHEMICO-BIOLOGICAL INTERACTIONS 8141 4% 1% 36
3 CHEMICAL RESEARCH IN TOXICOLOGY 6556 4% 1% 31
4 XENOBIOTICA 6195 3% 1% 26
5 MUTATION RESEARCH 4461 4% 0% 32
6 CANCER RESEARCH 2507 6% 0% 53
7 CANCER BIOCHEMISTRY BIOPHYSICS 2420 1% 1% 5
8 ARCHIVES OF TOXICOLOGY 2344 2% 0% 17
9 JOURNAL OF BIOCHEMICAL TOXICOLOGY 2213 0% 2% 4
10 DRUG METABOLISM REVIEWS 1745 1% 1% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 3 3 DICHLOROBENZIDINE 116517 1% 47% 7 Search 3+3+DICHLOROBENZIDINE Search 3+3+DICHLOROBENZIDINE
2 N 2 METHOXYPHENYLHYDROXYLAMINE 107012 0% 100% 3 Search N+2+METHOXYPHENYLHYDROXYLAMINE Search N+2+METHOXYPHENYLHYDROXYLAMINE
3 N ACETYLBENZIDINE 107012 0% 100% 3 Search N+ACETYLBENZIDINE Search N+ACETYLBENZIDINE
4 XENOBIOTIC OXIDATION 107012 0% 100% 3 Search XENOBIOTIC+OXIDATION Search XENOBIOTIC+OXIDATION
5 BENZIDINE 99051 2% 14% 20 Search BENZIDINE Search BENZIDINE
6 HYDROPEROXIDASE 97095 1% 39% 7 Search HYDROPEROXIDASE Search HYDROPEROXIDASE
7 C NITROSO AROMATICS 71341 0% 100% 2 Search C+NITROSO+AROMATICS Search C+NITROSO+AROMATICS
8 CO OXIDASE 71341 0% 100% 2 Search CO+OXIDASE Search CO+OXIDASE
9 FREE RADICALS OF PHENOTHIAZINES 71341 0% 100% 2 Search FREE+RADICALS+OF+PHENOTHIAZINES Search FREE+RADICALS+OF+PHENOTHIAZINES
10 N ACETYL DCB 71341 0% 100% 2 Search N+ACETYL+DCB Search N+ACETYL+DCB

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ZENSER, TV , LAKSHMI, AM , HSU, FF , DAVIS, BB , (2002) METABOLISM OF N-ACETYLBENZIDINE AND INITIATION OF BLADDER CANCER.MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. VOL. 506. ISSUE . P. 29-40 42 62% 38
2 GOLKA, K , KOPPS, S , MYSLAK, ZW , (2004) CARCINOGENICITY OF AZO COLORANTS: INFLUENCE OF SOLUBILITY AND BIOAVAILABILITY.TOXICOLOGY LETTERS. VOL. 151. ISSUE 1. P. 203-210 24 77% 186
3 ELING, TE , THOMPSON, DC , FOUREMAN, GL , CURTIS, JF , HUGHES, MF , (1990) PROSTAGLANDIN-H SYNTHASE AND XENOBIOTIC OXIDATION.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 30. ISSUE . P. 1-45 63 35% 255
4 KULKARNI, AP , (2001) ROLE OF BIOTRANSFORMATION IN CONCEPTAL TOXICITY OF DRUGS AND OTHER CHEMICALS.CURRENT PHARMACEUTICAL DESIGN. VOL. 7. ISSUE 9. P. 833 -857 59 32% 18
5 LAKSHMI, VM , HSU, FF , DAVIS, BB , ZENSER, TV , (2000) SULFINAMIDE FORMATION FOLLOWING PEROXIDATIC METABOLISM OF N-ACETYLBENZIDINE.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 13. ISSUE 2. P. 96-102 28 70% 0
6 HOVER, CG , KULKARNI, AP , (2000) LIPOXYGENASE-MEDIATED HYDROGEN PEROXIDE-DEPENDENT N-DEMETHYLATION OF N,N-DIMETHYLANILINE AND RELATED COMPOUNDS.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 124. ISSUE 3. P. 191 -203 27 66% 10
7 STIBOROVA, M , ASFAW, B , FREI, E , SCHMEISER, HH , (1996) OXIDATION OF AZO DYES BY PEROXIDASE: ADDITIONAL EVIDENCE OF A ONE-ELECTRON MECHANISM OF OXIDATION OF DIMETHYLAMINOAZOBENZENE AND SUDAN I (SOLVENT YELLOW 14).COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS. VOL. 61. ISSUE 6. P. 962-972 21 95% 15
8 HU, JA , KULKARNI, AP , (2000) METABOLIC FATE OF CHEMICAL MIXTURES. I. "SHUTTLE OXIDANT" EFFECT OF LIPOXYGENASE-GENERATED RADICAL OF CHLORPROMAZINE AND RELATED PHENOTHIAZINES ON THE OXIDATION OF BENZIDINE AND OTHER XENOBIOTICS.TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS. VOL. 20. ISSUE 4. P. 195 -208 24 73% 11
9 LAKSHMI, VM , ZENSER, TV , DAVIS, BB , (1998) N '-(3 '-MONOPHOSPHO-DEOXYGUANOSIN-8-YL)-N-ACETYLBENZIDINE FORMATION BY PEROXIDATIVE METABOLISM.CARCINOGENESIS. VOL. 19. ISSUE 5. P. 911 -917 31 58% 9
10 ZENSER, TV , LAKSHMI, VM , DAVIS, BB , (1998) N-GLUCURONIDATION OF BENZIDINE AND ITS METABOLITES - ROLE IN BLADDER CANCER.DRUG METABOLISM AND DISPOSITION. VOL. 26. ISSUE 9. P. 856-859 24 71% 27

Classes with closest relation at Level 1


Rank Class id link
1 25968 HUMAN S9//1 1 DIBROMOBENZENE//1 METHYL 2 ARYLETHYL HYDROXYLAMINE
2 28737 4 4 METHYLENEBIS2 CHLOROANILINE//METHYLENEDIANILINE//MBOCA
3 28642 DIRECT DYES//NONMUTAGENIC//4 4 DIAMINOBENZANILIDE
4 35388 PHENAZOPYRIDINE HYDROCHLORIDE//PHENAZOPYRIDINE//2 3 6 TRIAMINOPYRIDINE
5 20908 N 2 ACETYLAMINOFLUORENE//AMINOFLUORENE//ACETYLAMINOFLUORENE
6 5782 DNA ADDUCTS//I COMPOUNDS//P 32 POSTLABELING
7 23311 SUCCINIMIDES//N 3 5 DICHLOROPHENYLSUCCINIMIDE//SPLENIC TOXICITY
8 14891 NITRENIUM ION//NITRENIUM//ANOMERIC AMIDES
9 6238 ARYLAMINE N ACETYLTRANSFERASE//NAT2//N ACETYLTRANSFERASE
10 28644 O AMINOAZOTOLUENE//GLUCOCORTICOID INDUCTION//2 METHOXY 4 NITROANILINE

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