Class information for:
Level 1: CYP1A2//CAFFEINE//CAFFEINE METABOLISM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10694 1042 34.6 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
527 3       CAFFEINE//COFFEE//GREEN TEA 20032
1588 2             CAFFEINE//ENERGY DRINKS//COFFEE 7204
10694 1                   CYP1A2//CAFFEINE//CAFFEINE METABOLISM 1042

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYP1A2 authKW 552009 10% 18% 103
2 CAFFEINE authKW 380562 26% 5% 268
3 CAFFEINE METABOLISM authKW 279224 2% 53% 18
4 PARAXANTHINE authKW 131843 1% 30% 15
5 1 METHYLXANTHINE authKW 102554 1% 50% 7
6 CYP1A2 ACTIVITY authKW 95895 1% 55% 6
7 CAFFEINE OXIDATION authKW 87909 0% 100% 3
8 CYP1A2 POLYMORPHISM authKW 87909 0% 100% 3
9 CYTOCHROME P450 1A2 authKW 69506 1% 22% 11
10 1 METHYLURATE authKW 58606 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 3686 36% 0% 371
2 Toxicology 3563 18% 0% 187
3 Developmental Biology 406 4% 0% 45
4 Obstetrics & Gynecology 295 6% 0% 61
5 Nutrition & Dietetics 276 5% 0% 51
6 Public, Environmental & Occupational Health 237 7% 0% 78
7 Reproductive Biology 103 2% 0% 24
8 Pediatrics 95 4% 0% 45
9 Veterinary Sciences 62 4% 0% 40
10 Food Science & Technology 60 4% 0% 41

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PERINATAL NUTR METAB 43952 0% 50% 3
2 SECT DEV ENDOCRINOL BIOLYALE CHILD HLTH CT 39069 0% 67% 2
3 4376 KAMIYOGA SETAGAYA KU 29303 0% 100% 1
4 ANGARSK AFFILIATED 29303 0% 100% 1
5 BIOLFCM 29303 0% 100% 1
6 BIRTH DEFECTS PREVENT STUDY 29303 0% 100% 1
7 CANC GENET EPIDEMIOL BRANCH 29303 0% 100% 1
8 CANC HUMAN CARCINOGENESIS 29303 0% 100% 1
9 CHAIRE MED GROSSESSE ALLAITEMENT 29303 0% 100% 1
10 CHILD MATERNAL HLTH UNIT 29303 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOGENETICS 11157 2% 2% 19
2 TERATOLOGY 11015 3% 1% 27
3 CLINICAL PHARMACOLOGY & THERAPEUTICS 5436 3% 1% 33
4 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 5029 1% 2% 11
5 DRUG METABOLISM AND DISPOSITION 3471 3% 0% 30
6 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 3209 3% 0% 30
7 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2764 2% 0% 26
8 NEUROBEHAVIORAL TOXICOLOGY AND TERATOLOGY 2541 1% 1% 7
9 BIOLOGICAL RESEARCH IN PREGNANCY AND PERINATOLOGY 1878 0% 2% 3
10 FOOD AND CHEMICAL TOXICOLOGY 1800 2% 0% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYP1A2 552009 10% 18% 103 Search CYP1A2 Search CYP1A2
2 CAFFEINE 380562 26% 5% 268 Search CAFFEINE Search CAFFEINE
3 CAFFEINE METABOLISM 279224 2% 53% 18 Search CAFFEINE+METABOLISM Search CAFFEINE+METABOLISM
4 PARAXANTHINE 131843 1% 30% 15 Search PARAXANTHINE Search PARAXANTHINE
5 1 METHYLXANTHINE 102554 1% 50% 7 Search 1+METHYLXANTHINE Search 1+METHYLXANTHINE
6 CYP1A2 ACTIVITY 95895 1% 55% 6 Search CYP1A2+ACTIVITY Search CYP1A2+ACTIVITY
7 CAFFEINE OXIDATION 87909 0% 100% 3 Search CAFFEINE+OXIDATION Search CAFFEINE+OXIDATION
8 CYP1A2 POLYMORPHISM 87909 0% 100% 3 Search CYP1A2+POLYMORPHISM Search CYP1A2+POLYMORPHISM
9 CYTOCHROME P450 1A2 69506 1% 22% 11 Search CYTOCHROME+P450+1A2 Search CYTOCHROME+P450+1A2
10 1 METHYLURATE 58606 0% 100% 2 Search 1+METHYLURATE Search 1+METHYLURATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NEHLIG, A , DERBY, G , (1994) POTENTIAL TERATOGENIC AND NEURODEVELOPMENTAL CONSEQUENCES OF COFFEE AND CAFFEINE EXPOSURE - A REVIEW ON HUMAN AND ANIMAL DATA.NEUROTOXICOLOGY AND TERATOLOGY. VOL. 16. ISSUE 6. P. 531-543 117 79% 66
2 BRENT, RL , CHRISTIAN, MS , DIENER, RM , (2011) EVALUATION OF THE REPRODUCTIVE AND DEVELOPMENTAL RISKS OF CAFFEINE.BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY. VOL. 92. ISSUE 2. P. 152 -187 83 52% 41
3 PERERA, V , GROSS, AS , MCLACHLAN, AJ , (2012) MEASUREMENT OF CYP1A2 ACTIVITY: A FOCUS ON CAFFEINE AS A PROBE.CURRENT DRUG METABOLISM. VOL. 13. ISSUE 5. P. 667 -678 70 58% 19
4 CHRISTIAN, MS , BRENT, RL , (2001) TERATOGEN UPDATE: EVALUATION OF THE REPRODUCTIVE AND DEVELOPMENTAL RISKS OF CAFFEINE.TERATOLOGY. VOL. 64. ISSUE 1. P. 51 -78 77 71% 61
5 GROSSO, LM , BRACKEN, MB , (2005) CAFFEINE METABOLISM, GENETICS, AND PERINATAL OUTCOMES: A REVIEW OF EXPOSURE ASSESSMENT CONSIDERATIONS DURING PREGNANCY.ANNALS OF EPIDEMIOLOGY. VOL. 15. ISSUE 6. P. 460-466 55 77% 55
6 NEHLIG, A , DEBRY, G , (1994) CONSEQUENCES ON THE NEWBORN OF CHRONIC MATERNAL CONSUMPTION OF COFFEE DURING GESTATION AND LACTATION - A REVIEW.JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION. VOL. 13. ISSUE 1. P. 6-21 92 69% 34
7 PERERA, V , GROSS, AS , POLASEK, TM , QIN, Y , RAO, G , FORREST, A , XU, JZ , MCLACHLAN, AJ , (2013) CONSIDERING CYP1A2 PHENOTYPE AND GENOTYPE FOR OPTIMIZING THE DOSE OF OLANZAPINE IN THE MANAGEMENT OF SCHIZOPHRENIA.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 9. ISSUE 9. P. 1115 -1137 68 38% 5
8 HAKOOZ, NMK , (2009) CAFFEINE METABOLIC RATIOS FOR THE IN VIVO EVALUATION OF CYP1A2, N-ACETYLTRANSFERASE 2, XANTHINE OXIDASE AND CYP2A6 ENZYMATIC ACTIVITIES.CURRENT DRUG METABOLISM. VOL. 10. ISSUE 4. P. 329-338 45 59% 14
9 RHEE, J , KIM, R , KIM, Y , TAM, M , LAI, YZ , KEUM, N , OLDENBURG, CE , (2015) MATERNAL CAFFEINE CONSUMPTION DURING PREGNANCY AND RISK OF LOW BIRTH WEIGHT: A DOSE-RESPONSE META-ANALYSIS OF OBSERVATIONAL STUDIES.PLOS ONE. VOL. 10. ISSUE 7. P. - 29 69% 3
10 BOYLAN, S , CADE, JE , DOLBY, VA , GREENWOOD, DC , HAY, AWM , KIRK, SFL , SHIRES, S , SIMPSON, N , THOMAS, JD , WALKER, J , ET AL (2008) MATERNAL CAFFEINE INTAKE DURING PREGNANCY AND RISK OF FETAL GROWTH RESTRICTION: A LARGE PROSPECTIVE OBSERVATIONAL STUDY.BRITISH MEDICAL JOURNAL. VOL. 337. ISSUE . P. - 27 90% 9

Classes with closest relation at Level 1


Rank Class id link
1 18665 THEOBROMINE//CAFFEINE DETERMINATION//CAFFEINE
2 21239 DOXAPRAM//RESPIRATORY STIMULANTS//APNEA OF PREMATURITY
3 6725 ENERGY DRINKS//CAFFEINE//CAFFEINE WITHDRAWAL
4 25737 PL BENCH CORE//LAURA W BUSH WOMENS HLTH//PERINATAL NUTR METAB
5 10401 MEGX//MONOETHYLGLYCINEXYLIDIDE//LIVER FUNCTION
6 35869 FOOD DRUG EVALUAT//GENOMELAB GENE EXPRESSION PROFILER GEXP//GLUCOCORTICOID INSULIN LIKE GROWTH FACTOR 1 AXIS
7 7797 COFFEE//CAFESTOL//KAHWEOL
8 17103 ERGOGENIC AID//ERGOGENIC//EXERCISE TRAINING
9 21691 EXPT TERATOL UNIT//WAVY RIBS//GREY ZONE ANOMALIES
10 6238 ARYLAMINE N ACETYLTRANSFERASE//NAT2//N ACETYLTRANSFERASE

Go to start page