Class information for:
Level 1: DECITABINE//5 AZA 2 DEOXYCYTIDINE//ZEBULARINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5355 1635 50.2 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
563 3       DNA METHYLATION//EPIGENETICS//METHYLATION 17086
382 2             DNA METHYLATION//EPIGENETICS//METHYLATION 17086
5355 1                   DECITABINE//5 AZA 2 DEOXYCYTIDINE//ZEBULARINE 1635

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DECITABINE authKW 705427 7% 34% 112
2 5 AZA 2 DEOXYCYTIDINE authKW 578180 6% 29% 105
3 ZEBULARINE authKW 523135 3% 65% 43
4 DNA METHYLTRANSFERASE authKW 390988 8% 17% 124
5 DNMT3B authKW 356777 3% 36% 53
6 DNMT1 authKW 223292 4% 20% 59
7 DNA METHYLTRANSFERASE INHIBITOR authKW 207455 2% 37% 30
8 FAZARABINE authKW 169765 1% 91% 10
9 DNA METHYLATION authKW 168046 18% 3% 295
10 EPIGENETIC THERAPY authKW 131830 2% 22% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 14830 49% 0% 805
2 Hematology 950 8% 0% 132
3 Biochemistry & Molecular Biology 796 22% 0% 358
4 Cell Biology 698 12% 0% 202
5 Genetics & Heredity 624 9% 0% 154
6 Pharmacology & Pharmacy 534 13% 0% 211
7 Medicine, Research & Experimental 202 5% 0% 87
8 Chemistry, Medicinal 192 4% 0% 65
9 Toxicology 83 3% 0% 48
10 Pathology 48 2% 0% 37

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RECH PEDIAT 82402 1% 28% 16
2 SECT MDS 37349 0% 100% 2
3 EPIGENET GENE REGULAT CANC SECT 31117 0% 33% 5
4 GASTR COLORECTAL SURG 29221 0% 26% 6
5 LEUKEMIA EXPT THER EUT 24898 0% 67% 2
6 TRANSLAT CYT GRP 24898 0% 67% 2
7 CRUK BEATSON S 21336 0% 29% 4
8 CRDPF 21005 0% 38% 3
9 ADV TRANSLAT SCINIH 18674 0% 100% 1
10 ALLAHABAD BIOTECHNOL 18674 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL EPIGENETICS 3708 1% 2% 9
2 CANCER RESEARCH 3034 5% 0% 81
3 EPIGENOMICS 2571 0% 2% 8
4 INVESTIGATIONAL NEW DRUGS 2340 1% 1% 18
5 LEUKEMIA RESEARCH 2209 2% 0% 27
6 CIBA FOUNDATION SYMPOSIA 2193 1% 1% 18
7 INTERNATIONAL JOURNAL OF ONCOLOGY 1385 2% 0% 27
8 LEUKEMIA 1385 1% 0% 24
9 CANCER CHEMOTHERAPY AND PHARMACOLOGY 1307 1% 0% 23
10 ONCOGENE 1211 2% 0% 35

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DECITABINE 705427 7% 34% 112 Search DECITABINE Search DECITABINE
2 5 AZA 2 DEOXYCYTIDINE 578180 6% 29% 105 Search 5+AZA+2+DEOXYCYTIDINE Search 5+AZA+2+DEOXYCYTIDINE
3 ZEBULARINE 523135 3% 65% 43 Search ZEBULARINE Search ZEBULARINE
4 DNA METHYLTRANSFERASE 390988 8% 17% 124 Search DNA+METHYLTRANSFERASE Search DNA+METHYLTRANSFERASE
5 DNMT3B 356777 3% 36% 53 Search DNMT3B Search DNMT3B
6 DNMT1 223292 4% 20% 59 Search DNMT1 Search DNMT1
7 DNA METHYLTRANSFERASE INHIBITOR 207455 2% 37% 30 Search DNA+METHYLTRANSFERASE+INHIBITOR Search DNA+METHYLTRANSFERASE+INHIBITOR
8 FAZARABINE 169765 1% 91% 10 Search FAZARABINE Search FAZARABINE
9 DNA METHYLATION 168046 18% 3% 295 Search DNA+METHYLATION Search DNA+METHYLATION
10 EPIGENETIC THERAPY 131830 2% 22% 32 Search EPIGENETIC+THERAPY Search EPIGENETIC+THERAPY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KARAHOCA, M , MOMPARLER, RL , (2013) PHARMACOKINETIC AND PHARMACODYNAMIC ANALYSIS OF 5-AZA-2 '-DEOXYCYTIDINE (DECITABINE) IN THE DESIGN OF ITS DOSE-SCHEDULE FOR CANCER THERAPY.CLINICAL EPIGENETICS. VOL. 5. ISSUE . P. - 77 57% 52
2 GNYSZKA, A , JASTRZEBSKI, Z , FLIS, S , (2013) DNA METHYLTRANSFERASE INHIBITORS AND THEIR EMERGING ROLE IN EPIGENETIC THERAPY OF CANCER.ANTICANCER RESEARCH. VOL. 33. ISSUE 8. P. 2989-2996 42 86% 51
3 ERDMANN, A , HALBY, L , FAHY, J , ARIMONDO, PB , (2015) TARGETING DNA METHYLATION WITH SMALL MOLECULES: WHAT'S NEXT? MINIPERSPECTIVE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 6. P. 2569 -2583 68 51% 16
4 ZHANG, Y , XU, HS , SHEN, Y , GONG, ZM , XIAO, TL , (2015) ASSOCIATION OF DNMT3B-283 T > C AND-579 G > T POLYMORPHISMS WITH DECREASED CANCER RISK: EVIDENCE FROM A META-ANALYSIS.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE. VOL. 8. ISSUE 8. P. 13028 -13038 42 79% 0
5 GROS, C , FAHY, J , HALBY, L , DUFAU, I , ERDMANN, A , GREGOIRE, JM , AUSSEIL, F , VISPE, S , ARIMONDO, PB , (2012) DNA METHYLATION INHIBITORS IN CANCER: RECENT AND FUTURE APPROACHES.BIOCHIMIE. VOL. 94. ISSUE 11. P. 2280 -2296 75 37% 57
6 GOFFIN, J , EISENHAUER, E , (2002) DNA METHYLTRANSFERASE INHIBITORS - STATE OF THE ART.ANNALS OF ONCOLOGY. VOL. 13. ISSUE 11. P. 1699-1716 71 49% 166
7 ARTHUR, C , (2004) DECITABINE MGI PHARMA INC/SUPERGEN INC.IDRUGS. VOL. 7. ISSUE 12. P. 1113-1132 68 60% 0
8 SINGH, V , SHARMA, P , CAPALASH, N , (2013) DNA METHYLTRANSFERASE-1 INHIBITORS AS EPIGENETIC THERAPY FOR CANCER.CURRENT CANCER DRUG TARGETS. VOL. 13. ISSUE 4. P. 379 -399 72 32% 38
9 LIM, SP , NEILSEN, P , KUMAR, R , ABELL, A , CALLEN, DF , (2011) THE APPLICATION OF DELIVERY SYSTEMS FOR DNA METHYLTRANSFERASE INHIBITORS.BIODRUGS. VOL. 25. ISSUE 4. P. 227 -242 63 45% 5
10 COWAN, LA , TALWAR, S , YANG, AS , (2010) WILL DNA METHYLATION INHIBITORS WORK IN SOLID TUMORS? A REVIEW OF THE CLINICAL EXPERIENCE WITH AZACITIDINE AND DECITABINE IN SOLID TUMORS.EPIGENOMICS. VOL. 2. ISSUE 1. P. 71 -86 45 58% 27

Classes with closest relation at Level 1


Rank Class id link
1 22078 ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1
2 31935 DIETARY COMPOUNDS//MIR 1260B//3 UTR LUCIFERASE ASSAY
3 10356 METHYLTRANSFERASE ACTIVITY//DNA METHYLATION//METHYL BINDING DOMAIN PROTEIN
4 4391 DE NOVO METHYLATION//MYF 3//DNA METHYLATION
5 25695 IGLON//OPCML//NEUROTRIMIN
6 15761 LUNG CANC PROGRAM//HYPERMETHYLATION//MILTON J DANCE HEAD NECK
7 27163 MOL DIAGNOST RD//P16INK4A METHYLATION//TRIPLE COMBINATION ARRAY
8 14360 GSTP1//UNIDAD DOCENTE BIOQUIM BIOL MOL//DNA METHYLATION
9 1631 5 HYDROXYMETHYLCYTOSINE//DNA METHYLATION//5HMC
10 19894 CHFR//RING FINGER PROTEIN 180//EPIGEN

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