Class information for:
Level 1: ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22078 394 45.2 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
563 3       DNA METHYLATION//EPIGENETICS//METHYLATION 17086
382 2             DNA METHYLATION//EPIGENETICS//METHYLATION 17086
22078 1                   ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1 394

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ICF SYNDROME authKW 1313877 7% 63% 27
2 EXCELLENCE MOL GENET CANC HUMAN DIS address 1300955 8% 52% 32
3 COBRALINE 1 authKW 542501 2% 100% 7
4 HUMAN GENET PROGRAM SL31 address 523121 2% 75% 9
5 LINE 1 METHYLATION authKW 448387 2% 64% 9
6 DNA HYPOMETHYLATION authKW 413297 6% 22% 24
7 GLOBAL HYPOMETHYLATION authKW 407706 3% 48% 11
8 CENTROMERIC INSTABILITY authKW 379746 2% 70% 7
9 LINE 1 authKW 353594 9% 12% 37
10 HYPOMETHYLATION authKW 314865 8% 13% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Genetics & Heredity 2544 34% 0% 133
2 Oncology 2284 40% 0% 157
3 Cell Biology 279 15% 0% 60
4 Biochemistry & Molecular Biology 136 19% 0% 76
5 Pathology 133 6% 0% 23
6 Medicine, Research & Experimental 49 5% 0% 21
7 Gastroenterology & Hepatology 39 4% 0% 15
8 Medical Laboratory Technology 23 2% 0% 6
9 Toxicology 9 2% 0% 9
10 Developmental Biology 8 1% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXCELLENCE MOL GENET CANC HUMAN DIS 1300955 8% 52% 32
2 HUMAN GENET PROGRAM SL31 523121 2% 75% 9
3 INTER PROGRAM BIOMED SCI 247983 3% 27% 12
4 NUTR BIOCHEM MOL BIOL 193745 1% 50% 5
5 ASSOCIE INSERM LUMR S910 77500 0% 100% 1
6 BIOINFORMAT COMPUT BIOL 77500 0% 100% 1
7 BONE MARROW TYRANSPLANT UNIT 77500 0% 100% 1
8 BRIGHAM WOMENS HOSP MOL ONCOL PATHOL 77500 0% 100% 1
9 CANC BK21 77500 0% 100% 1
10 CANC COUNCIL CLIN TRIALS WA 77500 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL EPIGENETICS 4762 1% 1% 5
2 ASIAN BIOMEDICINE 2145 1% 1% 5
3 CYTOGENETICS AND CELL GENETICS 1844 2% 0% 9
4 EPIGENOMICS 1504 1% 1% 3
5 EPIGENETICS 1207 1% 1% 2
6 CIBA FOUNDATION SYMPOSIA 1016 2% 0% 6
7 PUERTO RICO HEALTH SCIENCES JOURNAL 905 1% 1% 2
8 HUMAN GENETICS 774 2% 0% 9
9 HUMAN GENOMICS 603 0% 1% 1
10 CYTOGENETIC AND GENOME RESEARCH 565 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ICF SYNDROME 1313877 7% 63% 27 Search ICF+SYNDROME Search ICF+SYNDROME
2 COBRALINE 1 542501 2% 100% 7 Search COBRALINE+1 Search COBRALINE+1
3 LINE 1 METHYLATION 448387 2% 64% 9 Search LINE+1+METHYLATION Search LINE+1+METHYLATION
4 DNA HYPOMETHYLATION 413297 6% 22% 24 Search DNA+HYPOMETHYLATION Search DNA+HYPOMETHYLATION
5 GLOBAL HYPOMETHYLATION 407706 3% 48% 11 Search GLOBAL+HYPOMETHYLATION Search GLOBAL+HYPOMETHYLATION
6 CENTROMERIC INSTABILITY 379746 2% 70% 7 Search CENTROMERIC+INSTABILITY Search CENTROMERIC+INSTABILITY
7 LINE 1 353594 9% 12% 37 Search LINE+1 Search LINE+1
8 HYPOMETHYLATION 314865 8% 13% 32 Search HYPOMETHYLATION Search HYPOMETHYLATION
9 ZBTB24 310000 1% 100% 4 Search ZBTB24 Search ZBTB24
10 CENTROMERE INSTABILITY 155000 1% 100% 2 Search CENTROMERE+INSTABILITY Search CENTROMERE+INSTABILITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 STERLIN, D , VELASCO, G , MOSHOUS, D , TOUZOT, F , MAHLAOUI, N , FISCHER, A , SUAREZ, F , FRANCASTEL, C , PICARD, C , (2016) GENETIC, CELLULAR AND CLINICAL FEATURES OF ICF SYNDROME: A FRENCH NATIONAL SURVEY.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 36. ISSUE 2. P. 149 -159 44 67% 2
2 HAGLEITNER, MM , LANKESTER, A , MARASCHIO, P , HULTEN, M , FRYNS, JP , SCHUETZ, C , GIMELLI, G , DAVIES, EG , GENNERY, A , BELOHRADSKY, BH , ET AL (2008) CLINICAL SPECTRUM OF IMMUNODEFICIENCY, CENTROMERIC INSTABILITY AND FACIAL DYSMORPHISM (ICF SYNDROME).JOURNAL OF MEDICAL GENETICS. VOL. 45. ISSUE 2. P. 93-99 34 89% 32
3 EHRLICH, M , JACKSON, K , WEEMAES, C , (2006) IMMUNODEFICIENCY, CENTROMERIC REGION INSTABILITY, FACIAL ANOMALIES SYNDROME (ICF).ORPHANET JOURNAL OF RARE DISEASES. VOL. 1. ISSUE . P. - 45 63% 37
4 KITKUMTHORN, N , MUTIRANGURA, A , (2011) LONG INTERSPERSED NUCLEAR ELEMENT-1 HYPOMETHYLATION IN CANCER: BIOLOGY AND CLINICAL APPLICATIONS.CLINICAL EPIGENETICS. VOL. 2. ISSUE . P. 315 -330 52 39% 38
5 EHRLICH, M , (2009) DNA HYPOMETHYLATION IN CANCER CELLS.EPIGENOMICS. VOL. 1. ISSUE 2. P. 239 -259 59 25% 209
6 BABA, Y , MURATA, A , WATANABE, M , BABA, H , (2014) CLINICAL IMPLICATIONS OF THE LINE-1 METHYLATION LEVELS IN PATIENTS WITH GASTROINTESTINAL CANCER.SURGERY TODAY. VOL. 44. ISSUE 10. P. 1807 -1816 36 38% 12
7 EHRLICH, M , SANCHEZ, C , SHAO, C , NISHIYAMA, R , KEHRL, J , KUICK, R , KUBOTA, T , HANASH, SM , (2008) ICF, AN IMMUNODEFICIENCY SYNDROME: DNA METHYLTRANSFERASE 3B INVOLVEMENT, CHROMOSOME ANOMALIES, AND GENE DYSREGULATION.AUTOIMMUNITY. VOL. 41. ISSUE 4. P. 253 -271 49 30% 54
8 VELASCO, G , WALTON, EL , STERLIN, D , HEDOUIN, S , NITTA, H , ITO, Y , FOUYSSAC, F , MEGARBANE, A , SASAKI, H , PICARD, C , ET AL (2014) GERMLINE GENES HYPOMETHYLATION AND EXPRESSION DEFINE A MOLECULAR SIGNATURE IN PERIPHERAL BLOOD OF ICF PATIENTS: IMPLICATIONS FOR DIAGNOSIS AND ETIOLOGY.ORPHANET JOURNAL OF RARE DISEASES. VOL. 9. ISSUE . P. - 21 66% 2
9 BARCHITTA, M , QUATTROCCHI, A , MAUGERI, A , VINCIGUERRA, M , AGODI, A , (2014) LINE-1 HYPOMETHYLATION IN BLOOD AND TISSUE SAMPLES AS AN EPIGENETIC MARKER FOR CANCER RISK: A SYSTEMATIC REVIEW AND META-ANALYSIS.PLOS ONE. VOL. 9. ISSUE 10. P. - 27 44% 17
10 KUTLUG, S , OGUR, G , YILMAZ, A , THIJSSEN, PE , ABUR, U , YILDIRAN, A , (2016) VESICOURETHRAL REFLUX-INDUCED RENAL FAILURE IN A PATIENT WITH ICF SYNDROME DUE TO A NOVEL DNMT3B MUTATION.AMERICAN JOURNAL OF MEDICAL GENETICS PART A. VOL. 170. ISSUE 12. P. 3253 -3257 13 100% 0

Classes with closest relation at Level 1


Rank Class id link
1 5355 DECITABINE//5 AZA 2 DEOXYCYTIDINE//ZEBULARINE
2 27163 MOL DIAGNOST RD//P16INK4A METHYLATION//TRIPLE COMBINATION ARRAY
3 10356 METHYLTRANSFERASE ACTIVITY//DNA METHYLATION//METHYL BINDING DOMAIN PROTEIN
4 19894 CHFR//RING FINGER PROTEIN 180//EPIGEN
5 5219 DNA METHYLATION//EWAS//EPIGENOME WIDE ASSOCIATION STUDY
6 14360 GSTP1//UNIDAD DOCENTE BIOQUIM BIOL MOL//DNA METHYLATION
7 31059 RLGS//RESTRICTION LANDMARK GENOMIC SCANNING//ZYGOTE ARREST 1
8 4391 DE NOVO METHYLATION//MYF 3//DNA METHYLATION
9 9828 SERRATED ADENOMA//SESSILE SERRATED ADENOMA//HYPERPLASTIC POLYP
10 1631 5 HYDROXYMETHYLCYTOSINE//DNA METHYLATION//5HMC

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