Class information for:
Level 1: PIOGLITAZONE//THIAZOLIDINEDIONES//ROSIGLITAZONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3093 2068 45.7 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
66 3       LEPTIN//ADIPONECTIN//ENDOCRINOLOGY & METABOLISM 84415
1300 2             THIAZOLIDINEDIONES//PPAR GAMMA//ROSIGLITAZONE 8578
3093 1                   PIOGLITAZONE//THIAZOLIDINEDIONES//ROSIGLITAZONE 2068

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PIOGLITAZONE authKW 1620213 17% 31% 357
2 THIAZOLIDINEDIONES authKW 1512813 18% 28% 367
3 ROSIGLITAZONE authKW 1213370 15% 26% 312
4 GLITAZONES authKW 157423 2% 27% 40
5 TROGLITAZONE authKW 134429 3% 14% 66
6 PPAR GAMMA authKW 85847 6% 5% 119
7 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA authKW 81209 4% 7% 77
8 PPAR GAMMA AGONIST authKW 77638 1% 19% 28
9 CARDIOVASC METAB MED DEV address 45206 0% 44% 7
10 RIVOGLITAZONE authKW 44292 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 12130 30% 0% 619
2 Peripheral Vascular Diseases 3905 13% 0% 275
3 Cardiac & Cardiovascular System 2319 14% 0% 293
4 Pharmacology & Pharmacy 2039 20% 0% 418
5 Medicine, General & Internal 1103 12% 0% 250
6 Urology & Nephrology 667 6% 0% 123
7 Medicine, Research & Experimental 516 7% 0% 145
8 Physiology 135 4% 0% 79
9 Hematology 129 3% 0% 67
10 Primary Health Care 39 1% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARDIOVASC METAB MED DEV 45206 0% 44% 7
2 FOR UNGSHEREICH ENDOKRINOL STOFFWECHSEL 29528 0% 100% 2
3 HOSP HEIDENHEIM 29528 0% 100% 2
4 SERV ENDOCRINOL DIABETOL MALADIES METABOL 29528 0% 100% 2
5 UIHC HYPERTENS 26573 0% 60% 3
6 D CAMPANACCI CLIN MED PL BIOTECHNOL 26561 0% 20% 9
7 VASC DIS PREVENT PROGRAM 26242 0% 44% 4
8 G DESCOVICH ATHEROSCLEROSIS STUDY 25502 1% 16% 11
9 FUNCT GENOM HYPERTENS 20433 0% 23% 6
10 COURSE ENDOCRINE SURG 19684 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PPAR RESEARCH 32885 2% 7% 33
2 DIABETES OBESITY & METABOLISM 30928 3% 3% 68
3 DIABETES CARE 7383 4% 1% 76
4 DIABETIC MEDICINE 5665 2% 1% 47
5 DIABETES & VASCULAR DISEASE RESEARCH 5252 1% 3% 12
6 CURRENT MEDICAL RESEARCH AND OPINION 4982 2% 1% 39
7 DIABETES RESEARCH AND CLINICAL PRACTICE 3968 2% 1% 38
8 JOURNAL OF DIABETES AND ITS COMPLICATIONS 3929 1% 1% 22
9 PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 2782 1% 1% 21
10 METABOLISM-CLINICAL AND EXPERIMENTAL 2740 2% 0% 41

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PIOGLITAZONE 1620213 17% 31% 357 Search PIOGLITAZONE Search PIOGLITAZONE
2 THIAZOLIDINEDIONES 1512813 18% 28% 367 Search THIAZOLIDINEDIONES Search THIAZOLIDINEDIONES
3 ROSIGLITAZONE 1213370 15% 26% 312 Search ROSIGLITAZONE Search ROSIGLITAZONE
4 GLITAZONES 157423 2% 27% 40 Search GLITAZONES Search GLITAZONES
5 TROGLITAZONE 134429 3% 14% 66 Search TROGLITAZONE Search TROGLITAZONE
6 PPAR GAMMA 85847 6% 5% 119 Search PPAR+GAMMA Search PPAR+GAMMA
7 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 81209 4% 7% 77 Search PEROXISOME+PROLIFERATOR+ACTIVATED+RECEPTOR+GAMMA Search PEROXISOME+PROLIFERATOR+ACTIVATED+RECEPTOR+GAMMA
8 PPAR GAMMA AGONIST 77638 1% 19% 28 Search PPAR+GAMMA+AGONIST Search PPAR+GAMMA+AGONIST
9 RIVOGLITAZONE 44292 0% 100% 3 Search RIVOGLITAZONE Search RIVOGLITAZONE
10 TYPE 2 DIABETES 42664 10% 1% 197 Search TYPE+2+DIABETES Search TYPE+2+DIABETES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GOLTSMAN, I , KHOURY, EE , WINAVER, J , ABASSI, Z , (2016) DOES THIAZOLIDINEDIONE THERAPY EXACERBATE FLUID RETENTION IN CONGESTIVE HEART FAILURE?.PHARMACOLOGY & THERAPEUTICS. VOL. 168. ISSUE . P. 75 -97 151 60% 0
2 FISHER, M , (2009) IMPROVING CARDIOVASCULAR RISK - APPLYING EVIDENCE-BASED MEDICINE TO GLUCOSE-LOWERING THERAPY WITH THIAZOLIDINEDIONES IN PATIENTS WITH TYPE 2 DIABETES.INTERNATIONAL JOURNAL OF CLINICAL PRACTICE. VOL. 63. ISSUE 9. P. 1354 -1368 82 79% 4
3 HUANG, JV , GREYSON, CR , SCHWARTZ, GG , (2012) PPAR-GAMMA AS A THERAPEUTIC TARGET IN CARDIOVASCULAR DISEASE: EVIDENCE AND UNCERTAINTY.JOURNAL OF LIPID RESEARCH. VOL. 53. ISSUE 9. P. 1738 -1754 105 50% 28
4 DOGGRELL, SA , (2008) CLINICAL TRIALS WITH THIAZOLIDINEDIONES IN SUBJECTS WITH TYPE 2 DIABETES - IS PIOGLITAZONE ANY DIFFERENT FROM ROSIGLITAZONE?.EXPERT OPINION ON PHARMACOTHERAPY. VOL. 9. ISSUE 3. P. 405-420 75 79% 13
5 MANNUCCI, E , MONAMI, M , LAMANNA, C , GENSINI, GF , MARCHIONNI, N , (2008) PIOGLITAZONE AND CARDIOVASCULAR RISK. A COMPREHENSIVE META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS.DIABETES OBESITY & METABOLISM. VOL. 10. ISSUE 12. P. 1221 -1238 70 74% 64
6 SCHERNTHANER, G , (2009) PLEIOTROPIC EFFECTS OF THIAZOLIDINEDIONES ON TRADITIONAL AND NON-TRADITIONAL ATHEROSCLEROTIC RISK FACTORS.INTERNATIONAL JOURNAL OF CLINICAL PRACTICE. VOL. 63. ISSUE 6. P. 912 -929 87 63% 20
7 ROHATGI, A , MCGUIRE, DK , (2008) EFFECTS OF THE THIAZOLIDINEDIONE MEDICATIONS ON MICRO- AND MACROVASCULAR COMPLICATIONS IN PATIENTS WITH DIABETES - UPDATE 2008.CARDIOVASCULAR DRUGS AND THERAPY. VOL. 22. ISSUE 3. P. 233 -240 65 88% 9
8 SARAFIDIS, PA , GEORGIANOS, PI , LASARIDIS, AN , (2011) PPAR-GAMMA AGONISM FOR CARDIOVASCULAR AND RENAL PROTECTION.CARDIOVASCULAR THERAPEUTICS. VOL. 29. ISSUE 6. P. 377 -384 56 90% 7
9 RIZOS, CV , KEI, A , ELISAF, MS , (2016) THE CURRENT ROLE OF THIAZOLIDINEDIONES IN DIABETES MANAGEMENT.ARCHIVES OF TOXICOLOGY. VOL. 90. ISSUE 8. P. 1861 -1881 87 49% 1
10 CIUDIN, A , HERNANDEZ, C , SIMO, R , (2012) UPDATE ON CARDIOVASCULAR SAFETY OF PPARGAMMA AGONISTS AND RELEVANCE TO MEDICINAL CHEMISTRY AND CLINICAL PHARMACOLOGY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 6. P. 585 -604 98 47% 16

Classes with closest relation at Level 1


Rank Class id link
1 15078 TROGLITAZONE//JTT 501//CS 045
2 3123 PPAR DELTA//PPAR BETA DELTA//PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
3 22786 GLICLAZIDE//ARTIFICIAL CELL MICROENCAPSULATION//BIOTECHNOL DRUG DEV
4 5985 15D PGJ2//15 DEOXY DELTA12 14 PROSTAGLANDIN J2//CYCLOPENTENONE PROSTAGLANDINS
5 25009 ANTIDIABETIC PHARMACOTHERAPY//A HEFT//ACORN CSD
6 13971 PRO12ALA POLYMORPHISM//PRO12ALA//PPAR GAMMA 2
7 9168 PPAR GAMMA//PPAR RESEARCH//TROGLITAZONE
8 1970 INSULIN GLARGINE//BIPHASIC INSULIN ASPART 30//INSULIN INITIATION
9 8850 METFORMIN//LACTIC ACIDOSIS//BIGUANIDES
10 16225 REPAGLINIDE//NATEGLINIDE//MITIGLINIDE

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