Class information for:
Level 1: PPAR GAMMA//PPAR RESEARCH//TROGLITAZONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9168 1182 49.7 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
66 3       LEPTIN//ADIPONECTIN//ENDOCRINOLOGY & METABOLISM 84415
1300 2             THIAZOLIDINEDIONES//PPAR GAMMA//ROSIGLITAZONE 8578
9168 1                   PPAR GAMMA//PPAR RESEARCH//TROGLITAZONE 1182

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PPAR GAMMA authKW 591892 20% 10% 236
2 PPAR RESEARCH journal 364528 7% 17% 83
3 TROGLITAZONE authKW 303859 6% 16% 75
4 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA authKW 221078 8% 9% 96
5 THIAZOLIDINEDIONES authKW 152076 7% 7% 88
6 CIGLITAZONE authKW 145682 2% 30% 19
7 ALPHA ARYLOXY ALPHA METHYLHYDROCINNAMIC ACID DERIVATIVE authKW 103328 0% 100% 4
8 TZD18 authKW 103328 0% 100% 4
9 PPAR GAMMA LIGAND authKW 103308 1% 29% 14
10 ROSIGLITAZONE authKW 83749 5% 5% 62

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 6486 39% 0% 459
2 Medicine, Research & Experimental 1023 12% 0% 141
3 Cell Biology 740 14% 0% 171
4 Biochemistry & Molecular Biology 358 18% 0% 218
5 Pharmacology & Pharmacy 279 11% 0% 135
6 Gastroenterology & Hepatology 168 4% 0% 52
7 Endocrinology & Metabolism 156 6% 0% 67
8 Pathology 106 3% 0% 40
9 Biophysics 92 4% 0% 51
10 Chemistry, Medicinal 33 2% 0% 28

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AFFILIATED WUJIN PEOPLES HOSP 59041 0% 57% 4
2 BIOMED MOL SCI PHARMACOL TOXICOL 58121 0% 75% 3
3 EA SIGNALISAT GENOM RECH TRANSLAT ONCOL SIGRETO 51664 0% 100% 2
4 AFFILIATED HOSPTONGJI MED 25832 0% 100% 1
5 ALIMENTAT CANCEROGENESE COL 25832 0% 100% 1
6 ALLEID HLTH SCI 25832 0% 100% 1
7 ANHUI DRUG CLIN EVALUAT 25832 0% 100% 1
8 ASAN LIFE SCI PATHOL 25832 0% 100% 1
9 AXIOM PLATFORM 25832 0% 100% 1
10 BIOL CELLULAIRE MOLEQUIPE ACCUEIL 3181 25832 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PPAR RESEARCH 364528 7% 17% 83
2 MOLECULAR CANCER THERAPEUTICS 1807 1% 0% 17
3 INTERNATIONAL JOURNAL OF ONCOLOGY 1794 2% 0% 26
4 MOLECULAR CARCINOGENESIS 1109 1% 0% 11
5 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 862 1% 1% 6
6 MOLECULAR PHARMACOLOGY 828 2% 0% 18
7 CLINICAL CANCER RESEARCH 807 2% 0% 22
8 ANTI-CANCER DRUGS 774 1% 0% 10
9 INTERNATIONAL JOURNAL OF CANCER 760 2% 0% 25
10 ENDOCRINE-RELATED CANCER 753 1% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PPAR GAMMA 591892 20% 10% 236 Search PPAR+GAMMA Search PPAR+GAMMA
2 TROGLITAZONE 303859 6% 16% 75 Search TROGLITAZONE Search TROGLITAZONE
3 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 221078 8% 9% 96 Search PEROXISOME+PROLIFERATOR+ACTIVATED+RECEPTOR+GAMMA Search PEROXISOME+PROLIFERATOR+ACTIVATED+RECEPTOR+GAMMA
4 THIAZOLIDINEDIONES 152076 7% 7% 88 Search THIAZOLIDINEDIONES Search THIAZOLIDINEDIONES
5 CIGLITAZONE 145682 2% 30% 19 Search CIGLITAZONE Search CIGLITAZONE
6 ALPHA ARYLOXY ALPHA METHYLHYDROCINNAMIC ACID DERIVATIVE 103328 0% 100% 4 Search ALPHA+ARYLOXY+ALPHA+METHYLHYDROCINNAMIC+ACID+DERIVATIVE Search ALPHA+ARYLOXY+ALPHA+METHYLHYDROCINNAMIC+ACID+DERIVATIVE
7 TZD18 103328 0% 100% 4 Search TZD18 Search TZD18
8 PPAR GAMMA LIGAND 103308 1% 29% 14 Search PPAR+GAMMA+LIGAND Search PPAR+GAMMA+LIGAND
9 ROSIGLITAZONE 83749 5% 5% 62 Search ROSIGLITAZONE Search ROSIGLITAZONE
10 EFATUTAZONE 68883 0% 67% 4 Search EFATUTAZONE Search EFATUTAZONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KOSTAPANOS, MS , ELISAF, MS , MIKHAILIDIS, DP , (2013) PIOGLITAZONE AND CANCER: ANGEL OR DEMON?.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 27. P. 4913-4929 133 62% 11
2 FROHLICH, E , WAHL, R , (2015) CHEMOTHERAPY AND CHEMOPREVENTION BY THIAZOLIDINEDIONES.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 104 76% 3
3 KRISHNAN, A , NAIR, SA , PILLAI, MR , (2007) BIOLOGY OF PPAR GAMMA IN CANCER: A CRITICAL REVIEW ON EXISTING LACUNAE.CURRENT MOLECULAR MEDICINE. VOL. 7. ISSUE 6. P. 532-540 66 83% 58
4 PETERS, JM , SHAH, YM , GONZALEZ, FJ , (2012) THE ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS IN CARCINOGENESIS AND CHEMOPREVENTION.NATURE REVIEWS CANCER. VOL. 12. ISSUE 3. P. 181 -195 85 39% 115
5 PANIGRAHY, D , SHEN, LQ , KIERAN, MW , KAIPAINEN, A , (2003) THERAPEUTIC POTENTIAL OF THIAZOLIDINEDIONES AS ANTICANCER AGENTS.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 12. ISSUE 12. P. 1925-1937 86 62% 57
6 SHU, LJ , HUANG, RH , WU, ST , CHEN, ZZ , SUN, K , JIANG, Y , CAI, XX , (2016) PPAR GAMMA AND ITS LIGANDS: POTENTIAL ANTITUMOR AGENTS IN THE DIGESTIVE SYSTEM.CURRENT STEM CELL RESEARCH & THERAPY. VOL. 11. ISSUE 3. P. 274 -281 63 65% 0
7 YOUSSEF, J , BADR, M , (2011) PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS AND CANCER: CHALLENGES AND OPPORTUNITIES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 164. ISSUE 1. P. 68 -82 75 55% 27
8 BOJKOVA, B , ORENDAS, P , KUBATKA, P , PEC, M , KASSAYOVA, M , KISKOVA, T , KAJO, K , (2014) POSITIVE AND NEGATIVE EFFECTS OF GLITAZONES IN CARCINOGENESIS: EXPERIMENTAL MODELS VS. CLINICAL PRACTICE.PATHOLOGY RESEARCH AND PRACTICE. VOL. 210. ISSUE 8. P. 465 -472 74 55% 0
9 FERRARI, SM , MATERAZZI, G , BALDINI, E , ULISSE, S , MICCOLI, P , ANTONELLI, A , FALLAHI, P , (2016) ANTINEOPLASTIC EFFECTS OF PPAR GAMMA AGONISTS, WITH A SPECIAL FOCUS ON THYROID CANCER.CURRENT MEDICINAL CHEMISTRY. VOL. 23. ISSUE 7. P. 636 -649 68 52% 1
10 GROMMES, C , LANDRETH, GE , HENEKA, MT , (2004) ANTINEOPLASTIC EFFECTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS.LANCET ONCOLOGY. VOL. 5. ISSUE 7. P. 419-429 52 67% 302

Classes with closest relation at Level 1


Rank Class id link
1 5985 15D PGJ2//15 DEOXY DELTA12 14 PROSTAGLANDIN J2//CYCLOPENTENONE PROSTAGLANDINS
2 3123 PPAR DELTA//PPAR BETA DELTA//PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
3 29356 REPROD METAB//ADIPQ//AIB3
4 13971 PRO12ALA POLYMORPHISM//PRO12ALA//PPAR GAMMA 2
5 15078 TROGLITAZONE//JTT 501//CS 045
6 3093 PIOGLITAZONE//THIAZOLIDINEDIONES//ROSIGLITAZONE
7 3761 PEROXISOME PROLIFERATOR//PEROXISOME PROLIFERATION//3 THIA FATTY ACIDS
8 6406 ADIPOGENESIS//ADIPOCYTE DIFFERENTIATION//MITOTIC CLONAL EXPANSION
9 10287 METFORMIN//ANTIDIABETIC BIGUANIDES//PHENFORMIN
10 17640 12S HETE//LY293111//ZYFLAMEND

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