Class information for:
Level 1: METFORMIN//LACTIC ACIDOSIS//BIGUANIDES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8850 1211 36.7 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
176 3       DIABETES CARE//ENDOCRINOLOGY & METABOLISM//TYPE 2 DIABETES 58057
1896 2             METFORMIN//ACARBOSE//REPAGLINIDE 5944
8850 1                   METFORMIN//LACTIC ACIDOSIS//BIGUANIDES 1211

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METFORMIN authKW 2038710 45% 15% 551
2 LACTIC ACIDOSIS authKW 585419 10% 19% 124
3 BIGUANIDES authKW 241906 4% 21% 45
4 METFORMIN ASSOCIATED LACTIC ACIDOSIS authKW 151280 0% 100% 6
5 EXTENDED RELEASE METFORMIN authKW 75640 0% 100% 3
6 BOWEL UPTAKE authKW 67233 0% 67% 4
7 NAZL INFORMAZ TOSSICOL address 56729 0% 75% 3
8 ORAL ANTI DIABETIC THERAPY authKW 56729 0% 75% 3
9 DIABETES & METABOLISM journal 51204 6% 3% 76
10 ACIDOSIS LACTIC CHEMICALLY INDUCED MORTALITY authKW 50427 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 11519 38% 0% 457
2 Pharmacology & Pharmacy 1754 24% 0% 289
3 Medicine, General & Internal 1185 16% 0% 190
4 Urology & Nephrology 125 4% 0% 45
5 Medicine, Research & Experimental 102 5% 0% 56
6 Primary Health Care 98 1% 0% 12
7 Toxicology 79 3% 0% 39
8 Peripheral Vascular Diseases 79 3% 0% 38
9 Emergency Medicine 54 1% 0% 13
10 Critical Care Medicine 46 2% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NAZL INFORMAZ TOSSICOL 56729 0% 75% 3
2 INT PHARMACOL SUPPORT 50427 0% 100% 2
3 LYONNAISE IND PHARMACEUT 50427 0% 100% 2
4 METAB CLIN DESIGN EVALUAT 50427 0% 100% 2
5 UNIT MEDICAT OUTCOMES EDUCPHARM 50427 0% 100% 2
6 COMPARAT BIOCHEM PHYSIOL 37817 0% 50% 3
7 ABT ANASTHESIOL U INTENSIVMED 25213 0% 100% 1
8 ADULT ENDOCRINOL DIABET METAB 25213 0% 100% 1
9 ALMM VET HOSP 25213 0% 100% 1
10 ALTALANOS ORVOSTUD KAR OKTATO OSZTALYA 25213 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABETES & METABOLISM 51204 6% 3% 76
2 DIABETES OBESITY & METABOLISM 16490 3% 2% 38
3 DIABETES-METABOLISM REVIEWS 8140 1% 3% 10
4 DIABETES CARE 6629 5% 0% 55
5 DIABETIC MEDICINE 6353 3% 1% 38
6 DIABETES RESEARCH AND CLINICAL PRACTICE 1873 2% 0% 20
7 METABOLISM-CLINICAL AND EXPERIMENTAL 1603 2% 0% 24
8 CLINICAL THERAPEUTICS 1442 1% 0% 17
9 HORMONE AND METABOLIC RESEARCH 1125 1% 0% 17
10 DIABETOLOGIA 955 1% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METFORMIN 2038710 45% 15% 551 Search METFORMIN Search METFORMIN
2 LACTIC ACIDOSIS 585419 10% 19% 124 Search LACTIC+ACIDOSIS Search LACTIC+ACIDOSIS
3 BIGUANIDES 241906 4% 21% 45 Search BIGUANIDES Search BIGUANIDES
4 METFORMIN ASSOCIATED LACTIC ACIDOSIS 151280 0% 100% 6 Search METFORMIN+ASSOCIATED+LACTIC+ACIDOSIS Search METFORMIN+ASSOCIATED+LACTIC+ACIDOSIS
5 EXTENDED RELEASE METFORMIN 75640 0% 100% 3 Search EXTENDED+RELEASE+METFORMIN Search EXTENDED+RELEASE+METFORMIN
6 BOWEL UPTAKE 67233 0% 67% 4 Search BOWEL+UPTAKE Search BOWEL+UPTAKE
7 ORAL ANTI DIABETIC THERAPY 56729 0% 75% 3 Search ORAL+ANTI+DIABETIC+THERAPY Search ORAL+ANTI+DIABETIC+THERAPY
8 ACIDOSIS LACTIC CHEMICALLY INDUCED MORTALITY 50427 0% 100% 2 Search ACIDOSIS+LACTIC+CHEMICALLY+INDUCED+MORTALITY Search ACIDOSIS+LACTIC+CHEMICALLY+INDUCED+MORTALITY
9 CAS 1115 70 4 50427 0% 100% 2 Search CAS+1115+70+4 Search CAS+1115+70+4
10 GLYBURIDE METFORMIN TABLETS 50427 0% 100% 2 Search GLYBURIDE+METFORMIN+TABLETS Search GLYBURIDE+METFORMIN+TABLETS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CUSI, K , DEFRONZO, RA , (1998) METFORMIN: A REVIEW OF ITS METABOLIC EFFECTS.DIABETES REVIEWS. VOL. 6. ISSUE 2. P. 89 -131 196 62% 180
2 DEFRONZO, R , FLEMING, GA , CHEN, K , BICSAK, TA , (2016) METFORMIN-ASSOCIATED LACTIC ACIDOSIS: CURRENT PERSPECTIVES ON CAUSES AND RISK.METABOLISM-CLINICAL AND EXPERIMENTAL. VOL. 65. ISSUE 2. P. 20 -29 60 81% 11
3 INZUCCHI, SE , LIPSKA, KJ , MAYO, H , BAILEY, CJ , MCGUIRE, DK , (2014) METFORMIN IN PATIENTS WITH TYPE 2 DIABETES AND KIDNEY DISEASE A SYSTEMATIC REVIEW.JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. VOL. 312. ISSUE 24. P. 2668 -2675 58 88% 81
4 CALELLO, DP , LIU, KD , WIEGAND, TJ , ROBERTS, DM , LAVERGNE, V , GOSSELIN, S , HOFFMAN, RS , NOLIN, TD , GHANNOUM, M , (2015) EXTRACORPOREAL TREATMENT FOR METFORMIN POISONING: SYSTEMATIC REVIEW AND RECOMMENDATIONS FROM THE EXTRACORPOREAL TREATMENTS IN POISONING WORKGROUP.CRITICAL CARE MEDICINE. VOL. 43. ISSUE 8. P. 1716 -1730 86 80% 6
5 SALPETER, SR , GREYBER, E , PASTERNAK, GA , SALPETER, EE , (2010) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 4. P. - 154 41% 14
6 SALPETER, SR , GREYBER, E , PASTERNAK, GA , SALPETER, EE , (2003) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS - SYSTEMATIC REVIEW AND META-ANALYSIS.ARCHIVES OF INTERNAL MEDICINE. VOL. 163. ISSUE 21. P. 2594-2602 99 65% 128
7 KAJBAF, F , DE BROE, ME , LALAU, JD , (2016) THERAPEUTIC CONCENTRATIONS OF METFORMIN: A SYSTEMATIC REVIEW.CLINICAL PHARMACOKINETICS. VOL. 55. ISSUE 4. P. 439 -459 79 65% 0
8 HOWLETT, HCS , BAILEY, CJ , (1999) A RISK-BENEFIT ASSESSMENT OF METFORMIN IN TYPE 2 DIABETES MELLITUS.DRUG SAFETY. VOL. 20. ISSUE 6. P. 489 -503 97 72% 108
9 SALPETER, S , GREYBER, E , PASTERNAK, G , SALPETER, E , (2003) RISK OF FATAL AND NONFATAL LACTIC ACIDOSIS WITH METFORMIN USE IN TYPE 2 DIABETES MELLITUS.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 3. P. - 110 63% 20
10 BAILEY, CJ , (1992) BIGUANIDES AND NIDDM.DIABETES CARE. VOL. 15. ISSUE 6. P. 755-772 81 76% 406

Classes with closest relation at Level 1


Rank Class id link
1 10287 METFORMIN//ANTIDIABETIC BIGUANIDES//PHENFORMIN
2 22786 GLICLAZIDE//ARTIFICIAL CELL MICROENCAPSULATION//BIOTECHNOL DRUG DEV
3 6705 GLIMEPIRIDE//JTT 608//SECONDARY FAILURE
4 16766 METFORMIN HYDROCHLORIDE//GLIMEPIRIDE//GLICLAZIDE
5 19276 LACTIC ACIDOSIS//TYPE B LACTIC ACIDOSIS//FLUORESCENT INTRACELLULAR H PROBE
6 3093 PIOGLITAZONE//THIAZOLIDINEDIONES//ROSIGLITAZONE
7 1970 INSULIN GLARGINE//BIPHASIC INSULIN ASPART 30//INSULIN INITIATION
8 15078 TROGLITAZONE//JTT 501//CS 045
9 16225 REPAGLINIDE//NATEGLINIDE//MITIGLINIDE
10 25009 ANTIDIABETIC PHARMACOTHERAPY//A HEFT//ACORN CSD

Go to start page